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1 ly receptor transmembrane activator and CAML interactor.
2 found that U1 snRNP is the most abundant FUS interactor.
3 dulation of CRISPR-Cas activity by a protein interactor.
4 or and calcium-modulating cyclophilin ligand interactor.
5 dentified tumor suppressor p27 as a PCTAIRE1 interactor.
6 nine kinase [8], as a putative novel anillin interactor.
7 t chain-related protein-1 (KLCR1) as an IQD1 interactor.
8 mbrane scaffolding protein, CASK, as a FRMD7 interactor.
9 L3MBTL3 (also known as MBT1) as a novel RBPJ interactor.
10 oprocessor component DROSHA as a novel DNMT1-interactor.
11 d DNA (ssDNA)-binding protein, as a novel G4 interactor.
12 th SR34 as bait and discovered SR45 as a new interactor.
13 ctions of PLEKHA7, we looked for new PLEKHA7 interactors.
14 echanism for bringing together their diverse interactors.
15 nexplored, as well as the discovery of novel interactors.
16 creened a siRNA library targeting known CFTR interactors.
17 ral sclerosis perturb a defined community of interactors.
18 unctions, likely via recruitment of specific interactors.
19 to be important for binding to many of these interactors.
20 nt for either PKA or PKG and their secondary interactors.
21 nvironments containing a myriad of potential interactors.
22 des to isolate each kinase and its secondary interactors.
23 damaged DNA (translesion synthesis) as TRIP interactors.
24 oup-level traits are neither replicators nor interactors.
25 stinct diseases, identified disease-specific interactors.
26 e mutations identified 50 disease-associated interactors.
27 raction with FD or 14-3-3 proteins, known FT interactors.
28 uency of both mutation genes and their close interactors.
29 t together with some of the newly identified interactors.
30 brid screen to identify potential substrates/interactors.
31 me, identifying 37 high-confidence candidate interactors.
32 eled cell lysates to quantitatively identify interactors.
33 ously identified to be in vivo genetic CLASP interactors.
34 sically linked to each other in vivo are LBC interactors.
35 subsequently validated many putative zDHHC17 interactors.
36 ating RNAPII, while P-TEFb was not among the interactors.
37 roteins, here we sought to identify new PP1c interactors.
38 affimer" reagents as high-affinity ubiquitin interactors.
39 independent experiments, to filter bona fide interactors.
42 the association of the adapter protein c-Abl interactor 1 (Abi1) with neuronal Wiskott-Aldrich syndro
43 identified mitofusin2 (MFN2) and Rab and Ras Interactor 1 (RIN1) as new Smad2 binding partners requir
45 anonical synaptic vesicle SNAREs Vps10p-tail-interactor-1a (vti1a) and vesicle-associated membrane pr
46 PPIs included both previously characterized interactors, along with a large subset of interactors th
48 tantly, we determined that a subset of these interactors also modified hLRRK2(I2020T) induced dopamin
50 a tomato UspA, is, to our knowledge, a novel interactor and phosphorylation target of a member of the
51 re mimicked by downregulation of OSBP, a VAP interactor and PI4P transporter that participates in VAP
52 -S100A10 protein complex as a novel Munc13-4 interactor and show that AnxA2-S100A10 participates in r
54 fied the tumor suppressor Pdcd4 as IBtkalpha interactor and ubiquitylation substrate of CRL3(IBTK) fo
55 tified several proteins including known BAK1 interactors and a previously uncharacterized LRR-RLP tha
56 f G-protein signaling (RGS) proteins are key interactors and critical modulators of the Galpha protei
57 sought to identify additional WW domain host interactors and demonstrate that the PPxY L domain motif
58 identify 638 individual high-confidence CFTR interactors and discover a F508 deletion-specific intera
59 ckdowns of sixteen previously identified Tat interactors and found that a novel E3 ligase, PJA2, ubiq
61 ge analysis revealed that although some HP1a interactors and regulators are broadly distributed withi
62 ority of the over four hundred putative HP1a interactors and regulators identified were previously un
63 performed a proteomic screen for novel HEG1 interactors and report that HEG1 binds directly to Rasip
64 a systematic map of disease-relevant lamin A interactors and suggest loss of tissue-specific lamin A
65 rane activator and calcium modulating ligand interactor, and B cell maturation antigen, at a stoichio
66 Ag (BCMA), transmembrane activator and CAML interactor, and BAFF receptor, in sorted human immune ce
67 cription, longer canonical transcripts, more interactors, and a higher number and more types of post-
68 on, we purified Drosophila melanogaster HP1a interactors, and performed a genome-wide RNAi screen to
72 itially identified in DNA damage repair, ATM-interactor (ATMIN) further functions as a transcriptiona
76 ork are discussed, with the most significant interactors being responses to hypoxia, regulation of ce
77 ence) of hnf4 and its predicted gene pathway interactors beta-catenin and hh Interestingly, the model
79 bonucleoprotein (hnRNP)-A2/B1 and hnRNP-R as interactors binding directly to the ASCL1 mRNA 5'- and 3
80 the affinity of RAB11B to a series of binary interactors, both effectors and guanine nucleotide excha
82 ort, we identified additional host WW-domain interactors by screening for potential interactions betw
83 , providing high-certainty identification of interactors by their direct access during cycling infect
86 g properties of each SH3 domain to the known interactor Casitas B-lineage lymphoma protein (c-CBL), c
88 kinase1 (BAK1) and several other known BRI1 interactors coimmunoprecipitated with BRL3, no evidence
90 , we show that Dyrk2 kinase, a reported UBR5 interactor, cooperates with UBR5 in mediating MOAP-1 ubi
93 sues and reproducibly retrieved at least one interactor for 81.4 % of the baits screened for in callu
95 y, our TAP protocol enables the discovery of interactors for low abundance proteins in rice and opens
96 ndidate synaptic cell-adhesion molecules, as interactors for the lectin-like domain of latrophilins.
97 deficient in several of the newly identified interactors for their capacity to secrete CCL22 in respo
101 metry generated a roster of disease-specific interactors functionally linked to lipid metabolism.
102 c protein partners were identified, with the interactors functioning mainly in DNA maintenance and mi
107 x protein CHD4, and the repressive chromatin interactor HP1BP3, by co-immunoprecipitation combined wi
109 e the downstream analysis of >2000 potential interactors identified in high-throughput experiments.
112 -specific Lyn substrate-1) is a cytoskeletal interactor in the B-cell receptor (BCR) signaling pathwa
116 ity to detect proximal proteins and putative interactors in intact tissues, and to quantify changes c
117 ealed several TCR adaptor proteins acting as interactors in stimulated cells, of which LAT and Trat1
124 analysis of four ncRNAs captures key protein interactors, including a U1-specific link to the 3' RNA
125 lar RNAs (snoRNAs) were identified as coilin interactors, including numerous unannotated mouse and hu
126 suppression, since the expression of several interactors, including some of the above-noted transcrip
127 coimmunoprecipitates with several key Atg11 interactors, including the Atg1/Unc-51-like autophagy ac
129 thus able to discover a number of novel Rif1 interactors, involved in chromatin metabolism and phosph
130 e assembly of complexes comprising the Cdc42-interactor IQGAP1, the Rho GTPase-activating protein ARH
133 A list of non-specific and false positive interactors is presented, based on re-occurrence over mo
134 orted that expression of NMI (N-myc and STAT interactor) is compromised in invasive breast cancers.
137 identified a novel and functional EBOV VP40 interactor, ITCH, that regulates VP40-mediated egress.
138 y described functions of several known CLASP interactors, its multiparametric resolution reveals more
139 IM-actin-MKL1 sequence, we identify the MKL1 interactor Jumonji domain demethylase 1A (JMJD1A) as a n
140 aging, we identified the Kif1B motor and its interactor Kif1 binding protein (KBP) as critical for SC
141 conformation, which prevents its binding to interactors known to be involved in membrane fission and
143 and identity of component species, as strong interactors like foundation species have the potential t
147 e possibility that targeting NRP1 or its NCD interactors may be a useful therapeutic strategy in neov
148 ural response appeared not influenced in the interactor mutants katA and acnB in steady-state behavio
149 Phenotyping of 124 Arabidopsis effector-interactor mutants revealed a correlation between intras
150 bind to either the LIM cofactor nuclear LIM interactor (NLI) or another LIM homeodomain factor, Isl1
151 Based on this approach, we identified N-Myc interactor (NMI) as an IRE1alpha-interacting/modulator p
152 e have observed that the expression of N-myc interactor (NMI) decreases significantly during progress
154 giectasia mutated) phosphorylation-dependent interactor of 53BP1 and show that absence of Rif1 result
155 ALG-2 interacting protein X (Alix/AIP1), an interactor of apoptosis-linked gene protein 2 (ALG-2).
157 identify a protein named TSSC1 as a specific interactor of both GARP and EARP and as a novel componen
158 d heat shock protein 70 (HSP70) as a protein interactor of both wild type and Crohn mutant NOD2.
159 ntified the RING finger protein RNF181 as an interactor of CARD11, a key signaling scaffold in the an
160 olvement of the RHO of Plants (ROP) effector INTERACTOR of CONSTITUTIVELY active ROP 1 (ICR1) in regu
161 5' RNA degradation machinery, as a physical interactor of CP190-dependent chromatin insulator comple
163 ting protein 2 (Cyfip2) was identified as an interactor of FMRP, and its mRNA is a highly ranked FMRP
164 Subsequently, we identified Sp110 as a novel interactor of HBx and found this association to be essen
168 All three lines harbored mutations in Novel Interactor of JAZ (NINJA), which encodes part of a repre
170 at NS5A protein represents the most probable interactor of M3R or that this viral protein could elici
172 a screening assay, we identified CRKII as an interactor of oncogenic EGFR(L858R) and showed that CRKI
174 main-containing protein 11 (PDZD11) as a new interactor of PLEKHA7 by yeast two-hybrid screening and
175 dentified cortactin as a novel substrate and interactor of proline-rich tyrosine kinase 2 (Pyk2).
176 ET) we identified alpha-synuclein as a novel interactor of PSEN1 in wild-type mouse brain tissue.
178 he signaling protein TIF1gamma as a specific interactor of SnoN1 but not the closely related isoform
181 on experiments established DGCR8 as a direct interactor of Tcf7l1 mRNA, a core component of the pluri
185 RGO-1 pathway, including eri-12, encoding an interactor of the RNAi-defective protein RDE-10, and ntl
186 alling and identify Axin1 as a novel protein interactor of the widely-expressed gamma-Pcdh-C3 isoform
187 like (Mid1ip1l), previously identified as an interactor of the X-linked Opitz G/BBB syndrome gene pro
192 vidence for existence of Gly-Trp (GW) repeat interactors of AGO proteins acting in the plant microRNA
193 mass spectrometry analysis for brain-derived interactors of ArPIKfyve-Sac3 and unraveled the alpha-sy
196 eleton regulators as previously unrecognized interactors of complexes associated with the Hermansky-P
197 rtin (IMP) family of nuclear transporters as interactors of Ei24 and characterize an IMPbeta-binding-
199 mary tissue as well as the identification of interactors of insoluble proteins that form higher-order
203 hermore, transposon mutagenesis of oxa-23 or interactors of Oxa-23 demonstrates changes in meropenem
204 finity-purification and mass spectrometry of interactors of the centrosomal and ciliopathy protein, C
207 pressed genes showed enrichment for putative interactors of the first three identified COPD GWAS gene
210 we found differential expression of putative interactors of these genes, and we replicated previous h
211 domain-containing proteins and ALKBH5, known interactors of this modification, we find that FMR1 and
212 were also detected between BRCA1 and certain interactors of TONSL, including both members of the FACT
214 and calcium modulator and cyclophilin ligand interactor) on GC B cells, thus limiting their capacity
215 xpressing AMLs, that Hoxa genes and selected interactors or downstream targets are required for survi
219 -3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4
220 h diverse proteins, and its most predominant interactors play important roles in postsynaptic recepto
221 ion, disease association, protein structure, interactors, posttranslational modifications, and inhibi
224 ppGpp, but not the previously described YfgM interactors RcsB and PpiD, influence YfgM degradation.
225 ed that caveolin 1 (CAV1), a well-known eNOS interactor, regulates eNOS activity in sinusoidal endoth
226 We have identified a conserved protein and interactors required for maintaining cell adhesion durin
229 mutants did not depend on the SHR functional interactor SCARECROW and the sugar signaling component A
230 alysis of Arabidopsis homologs of BjNRAMP4.1 interactors showed enrichment of many protein components
231 Quantitative proteomic analysis of polyQ interactors showed that expression of Gts1p reduced the
232 F-dependent transmembrane activator and CAML interactor signals in atherosclerosis pathogenesis, of p
235 ding the transcriptional repressor and MeCP2 interactor switch-insensitive 3 family member A (SIN3A;
236 or and calcium-modulating cyclophilin ligand interactor (TACI) are found in 8% to 10% of subjects wit
237 gen (BCMA), transmembrane activator and CAML interactor (TACI) but not to the BAFF receptor (BAFFR).
238 or and calcium-modulating cyclophilin ligand interactor (TACI) controls differentiation of long-lived
239 How mutant transmembrane activator and CAML interactor (TACI) influences wild-type TACI function is
240 brane activator and calcium modulator ligand interactor (TACI) is important for T-independent antibod
242 and calcium-modulator and cyclophilin ligand interactor (TACI) was severely reduced in XID B cells.
243 ro of CD86, transmembrane activator and CAML interactor (TACI), and CD23 activation markers after TLR
244 and calcium-modulator and cyclophilin ligand interactor (TACI), is a key molecule for plasma cell mai
249 n 102 (SAP102) was identified as a candidate interactor that bound to the A2A receptor C terminus.
250 unconventional prefoldin, RNA polymerase II interactor that functions as a transcriptional repressor
251 roduced to enlarge the range of proteins and interactors that can be assayed by hybrid-based approach
252 ed interactors, along with a large subset of interactors that have not been previously identified as
253 e of which are potential stage-specific mRNA interactors that likely reflect the dynamics of RNA-prot
256 viability, we uncovered a novel role for its interactor, the ESCRT-I protein TSG101: it directly part
259 ty-regulated cytoskeleton-associated protein interactors, the fragile X mental retardation protein co
261 tellite proteins localize their cognate MCPH interactors to centrosomes and also promote centriole du
262 Harnessing the ability of these protein interactors to transform the oncogenic mutant p53 to the
265 monstrate that unconventional prefoldin RPB5 interactor (URI) expression in hepatocytes leads to hepa
266 expression of unconventional prefoldin RPB5 interactor (URI) leads to a multistep process of HCC dev
267 in 6 (DPP6) was first identified as a PrP(C) interactor using in vivo formaldehyde cross-linking of w
268 P, we sought to identify direct IRF6 protein interactors using a combination of yeast 2-hybrid screen
269 tome of PAX3-FOXO1 and screened 60 candidate interactors using siRNA-mediated depletion to identify c
270 AF patients, with CSDA and PDE5A being novel interactors validated by bioinformatics, immunocytochemi
271 identified polypeptides represent bona fide interactors versus those that are background contaminant
272 ins, including several highly specific ACTN4 interactors, was globally decreased in the patient-deriv
275 From a screen for functionally relevant ERG interactors, we identify the arginine methyltransferase
282 ore proteins ABC1K3, PES1, and CCD4 as PGM48 interactors, whereas several other PG-localized proteins
283 rification allowed copurifying PSBS with its interactors, which were identified by mass spectrometry
286 interactome remodelling identifies key novel interactors, whose loss promote F508 CFTR channel functi
287 g approaches, we demonstrate that the N-WASP-interactors WIP and WICH/WIRE play non-redundant roles i
288 transferase, which we identified as a strong interactor with all three TET proteins, catalyzes the ad
291 ment binding protein superfamily, as a DELLA interactor with physiological relevance in the context o
292 analysis identified annexinA2 as a potential interactor with the extracellular domains of PLA2R.
293 d the ubiquitin-modifying enzyme TRAF6 as an interactor with the integrin beta1 subunit and regulator
294 ting Protein 1 (Cnrip1) was discovered as an interactor with the intracellular region of Cannabinoid
295 ow that Scribble PDZ1 and PDZ3 are the major interactors with beta-PIX and reveal a distinct binding
299 Here we used mAb technology to identify interactors with Z alpha1-antitrypsin that comply with b
300 d 69 negative and 82 positive common genetic interactors, with functions related to cellular growth a
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