ライフサイエンスコーパス: intercellular bridge

1 o the midbody and direct the severing of the intercellular bridge.

2 scission until chromatin is cleared from the intercellular bridge.

3 roposed to attach the cleavage furrow to the intercellular bridge.

4 body structure, located at the center of the intercellular bridge.

5 r abscission to an integral component of the intercellular bridge.

6 e of the midbody matrix in the middle of the intercellular bridge.

7 nd keeps the daughter cells connected via an intercellular bridge.

8 into separate cells or formation of a stable intercellular bridge.

9 rce subsequently mediates cytofission of the intercellular bridge.

10 ase, staining shifted to the midbody and the intercellular bridge.

11 identifying molecular mechanisms regulating intercellular bridges.

12 erring stability and elasticity to germ cell intercellular bridges.

13 to a shared cytoplasm core (the rachis) via intercellular bridges.

14 gether to prevent abscission and form stable intercellular bridges.

15 ls that are interconnected by TEX14-positive intercellular bridges.

16 a novel protein that localizes to germ cell intercellular bridges.

17 whereby cells remain interconnected by long intercellular bridges.

18 d throughout the group by spread through the intercellular bridges.

19 regulatory molecules cannot occur via these intercellular bridges.

20 anillin and non-muscle myosin II (NMM-II) to intercellular bridges.

21 ytokinetic rings are enriched on stably open intercellular bridges [1, 3, 4].

22 s are held together by a combination of fine intercellular bridges, a shared extracellular matrix, an

23 Germ cells in most animals are connected by intercellular bridges, actin-based rings that form stabl

24 nillin RNAi caused gradual disruption of the intercellular bridge after furrowing; citron-kinase RNAi

25 rovides both structural support for a narrow intercellular bridge and a platform that orchestrates th

26 targeting, which promotes maturation of the intercellular bridge and abscission.

27 that CEP55 becomes a stable component of the intercellular bridge and that an evolutionarily conserve

28 nd ANI-2 loss resulted in destabilization of intercellular bridges and germ cell multinucleation defe

29 ve information about the morphology of these intercellular bridges and the extent of their distributi

30 apoptosis during cytokinesis with unresolved intercellular bridges, and rescue experiments show that

31 Intercellular bridges are a conserved feature of multice

32 Although these findings demonstrate that intercellular bridges are essential for spermatogenesis,

33 In the absence of TEX14, intercellular bridges are not observed by using electron

34 Intercellular bridges are proposed to arise from stabili

35 Ring canals, also known as stable intercellular bridges, are derived from the contractile

36 force propels the fission complex along the intercellular bridge away from the midbody until it reac

37 ial core of the Stan system is an asymmetric intercellular bridge between Stan in one cell and Stan a

38 owth of actin-rich ring canals, which act as intercellular bridges between germ cells.

39 rst 52 amino acids (CHMP6-N), arrives at the intercellular bridge, blocks abscission, and subsequentl

40 N does not interfere with its arrival at the intercellular bridge but almost completely abolishes the

41 itosis, centralspindlin is maintained at the intercellular bridge by anillin, and CYK-4 is localized

42 ms an arrested cleavage furrow into a stable intercellular bridge by the addition of several proteins

43 Intercellular bridges called "ring canals" (RCs) resulti

44 structure known as a fusome extrudes through intercellular bridges called ring canals.

45 ular fungi, cells are connected directly via intercellular bridges called septal pores.

46 ts these midbody matrix proteins into stable intercellular bridge components.

47 osophila ovarian follicles, cytoplasm-filled intercellular bridges connect epithelial cells.

48 germ cell cytokinesis results in a permanent intercellular bridge connecting the daughter cells throu

49 oteins form highly ordered structures at the intercellular bridge during abscission progression.

50 of CaBP7 with lysosomes that cluster at the intercellular bridge during cytokinesis in HeLa cells.

51 to other germ cell proteins to form a stable intercellular bridge essential for male reproduction.

52 e of Drosophila melanogaster is required for intercellular bridge formation during cytokinesis in mal

53 o proteins essential for mammalian germ cell intercellular bridge formation have been identified.

54 to the conceptus through persistence of the intercellular bridge formed during its abstriction, and

55 sequentially recruited to the center of the intercellular bridge, forming a series of cortical rings

56 family scaffold protein ANI-2 is enriched at intercellular bridges from the onset of germ cell specif

57 vity exhibit two distinct defects: disrupted intercellular bridges (fusomes) and premature centriole

58 ntial components of the vertebrate germ cell intercellular bridge have until now not been described.

59 es to the spindle midzone and the subsequent intercellular bridge in mammalian cells and is also enri

60 zation and function at a stable, postmitotic intercellular bridge in the Caenorhabditis elegans gonad

61 own that targeted deletion of TEX14 disrupts intercellular bridges in all germ cells and causes male

62 lts, negative regulators of NMM-II stabilize intercellular bridges in the Drosophila egg chamber [10,

63 find that mouse germ cells are connected by intercellular bridges in the ovaries of 11.5 to 17.5 day

64 Thus, TEX14 is required for intercellular bridges in vertebrate germ cells, and thes

65 ring spermatogenesis, proposed roles for the intercellular bridge include germ cell communication, sy

66 sis concludes with the formation of a stable intercellular bridge interconnecting daughter cells in a

67 and these studies provide evidence that the intercellular bridge is essential for spermatogenesis an

68 We have shown that the stability of the intercellular bridge is essential for successful cytokin

69 duces lysosome mislocalization, extension of intercellular bridge lifetime, and cytokinesis failure.

70 complex generates bending deformation of the intercellular bridge membrane.

71 Fibrinogen-dependent intercellular bridging occurred in venules, but not in a

72 ing body and thinning of microtubules in the intercellular bridge of cells depleted of LARG is consis

73 letely separate and remain interconnected by intercellular bridges or ring canals.

74 s isolated, coincident with formation of the intercellular bridge; proper progression through this st

75 Although intercellular bridges resulting from incomplete cytokine

76 M-3, a known binding partner [9], to promote intercellular bridge stability and limit localization of

77 Given this inconsistency, the mechanism of intercellular bridge stabilization is unclear.

78 t with the localization of NMHC II-C1 to the intercellular bridge that attaches the two dividing cell

79 conserved mechanism for the stabilization of intercellular bridges that can occur by diverse molecula

80 Instead, daughter cells remain connected by intercellular bridges that contain bundled microtubules

81 the extent and distribution of follicle cell intercellular bridges to be confined to arrays of no mor

82 Using TEX14 as a marker for the germ cell intercellular bridge, we show that TEX14 co-localizes wi

83 g a biochemical enrichment of male germ cell intercellular bridges, we identified additional bridge p

84 t tension contributes to the severing of the intercellular bridge when cytokinesis is completed.

85 ed to the spindle midzone and the subsequent intercellular bridge, where it plays an essential role i

86 cle with daughter cells connected by a large intercellular bridge with a prominent midbody.

87 ds until the formation of a microtubule-rich intercellular bridge with the midbody at its centre.