ライフサイエンスコーパス: intercellular junction

1 -mediated feedback is a global effect on the intercellular junction.

2 actin polymerization complex at the podocyte intercellular junction.

3 tern of receptor proteins (a synapse) in the intercellular junction.

4 is a major component of the endothelial cell intercellular junction.

5 with IL-4, suggesting that IL-4 modifies the intercellular junction.

6 in and actin filaments are enriched near the intercellular junction.

7 mediated redistribution of occludin from the intercellular junctions.

8 ity complexes participate in the assembly of intercellular junctions.

9 diate adhesion and signaling at a variety of intercellular junctions.

10 with host membrane protrusions located near intercellular junctions.

11 ) are a family of adhesion proteins found in intercellular junctions.

12 hat Src and Cas associate with each other at intercellular junctions.

13 protein-tagged UNC-9 was localized to muscle intercellular junctions.

14 d vesicles and the consequent disassembly of intercellular junctions.

15 ll contacts and facilitated the formation of intercellular junctions.

16 pitates with ZO-1 and partially localizes to intercellular junctions.

17 sed throughout the nephron, predominantly at intercellular junctions.

18 oskeleton and proper positioning/assembly of intercellular junctions.

19 olocalized with cadherins and connexin 43 in intercellular junctions.

20 having inclusion bodies now, retained normal intercellular junctions.

21 r barrier and the re-establishment of apical intercellular junctions.

22 from the intracellular compartment into the intercellular junctions.

23 ractions on the organization and function of intercellular junctions.

24 ctivation, thus changing the organization of intercellular junctions.

25 ar overlap, catalyzing new sites for nascent intercellular junctions.

26 expression of p0071 could displace p120 from intercellular junctions.

27 -1 forms during assembly of endothelial cell intercellular junctions.

28 to the membrane ruffles and the loosening of intercellular junctions.

29 ested by membrane ruffling and disruption of intercellular junctions.

30 al inoculation was overcome by disruption of intercellular junctions.

31 last- (NRK-49F) or epithelial-like (NRK-52E) intercellular junctions.

32 ranuclear speckles, and unexpectedly also in intercellular junctions.

33 elial cell monolayers, prior to formation of intercellular junctions.

34 sphorylated Cx43 signal occurred at sites of intercellular junctions.

35 d localization of cadherin and connexin43 at intercellular junctions.

36 nd with a putative role in the disruption of intercellular junctions.

37 an emphasis on regulation of the specialized intercellular junctions.

38 diate adhesion and signaling at a variety of intercellular junctions.

39 luminal surfaces; alpha(v) and VLA-1 were on intercellular junctions.

40 ssary to stabilize the receptors at sites of intercellular junctions.

41 43 phosphorylation and the loss of Cx43 from intercellular junctions.

42 ns/hour, indicating no appreciable damage to intercellular junctions.

43 ls and as clusters of cells held together by intercellular junctions.

44 cell proliferation, signaling pathways, and intercellular junctions.

45 ed the coupling coefficient (KC), across the intercellular junctions.

46 uding a lacunar system and multiple types of intercellular junctions.

47 ation and proper organization of VE-cadherin intercellular junctions.

48 in cadherin-specific mechanotransduction at intercellular junctions.

49 RNA miR-199a-5p as an important regulator of intercellular junctions.

50 TC-dextran leakage, indicating disruption of intercellular junctions.

51 At P30, staining was localized to intercellular junctions.

52 in length before failing through rupture of intercellular junctions.

53 ocyanate-dextran flux; P < .05) and impaired intercellular junctions.

54 unction proteins occludin and claudin-2 from intercellular junctions.

55 how ECM affects the spatial organization of intercellular junctions.

56 rentially spread from cell-to-cell at unique intercellular junctions.

57 ons and recruited by the cadherin complex to intercellular junctions.

58 ocated the chief sites of insulin release to intercellular junctions.

59 ))-beta(1) co-precipitation and strengthened intercellular junctions.

60 ture can regulate stability and tightness of intercellular junctions.

61 "leaky" tight junction protein claudin-2 at intercellular junctions.

62 transition, leading to transient opening of intercellular junctions.

63 otes localized accumulation of E-cadherin at intercellular junctions.

64 adhesive plasma membrane structures known as intercellular junctions.

65 mple, CD46 and Her2/neu, that are trapped in intercellular junctions.

66 s an important early step in the assembly of intercellular junctions.

67 ted remodeling of the actin cytoskeleton and intercellular junctions.

68 ntemporaneous with the development of stable intercellular junctions [1].

69 ymphatic endothelial cell quiescence through intercellular junction and cytoskeleton stabilization an

70 and Connexin 30 from epidermal keratinocyte intercellular junctions and accumulation in cytoplasm.

71 ed at high concentration at endothelial cell intercellular junctions and at moderate density on the s

72 ial monolayers also developed focal adherens intercellular junctions and became more permeable when c

73 ical role because it controls cadherin-based intercellular junctions and cell polarity in many specie

74 present at dermal microvascular endothelial intercellular junctions and colocalizes with VE-cadherin

75 thereby increasing pore size of endothelial intercellular junctions and enhancing movement across th

76 or "edge" cells, as the hepatocytes acquire intercellular junctions and form islands with time in cu

77 ionships between assembly and maintenance of intercellular junctions and highlight unappreciated role

78 e encodes a CDM family member that regulates intercellular junctions and is disrupted during tumorige

79 otifs responsible for ZO-1's localization to intercellular junctions and its newly demonstrated local

80 c protein alpha-catenin from E-cadherin-rich intercellular junctions and loss of adhesion.

81 s in regulating the formation of endocardial intercellular junctions and maintaining endocardial iden

82 odeling, interconversion of autocellular and intercellular junctions and migration over a luminal ext

83 PKPs localize to the cytoplasmic plaque of intercellular junctions and participate in linking the i

84 porting cell processes with normal-appearing intercellular junctions and portions of extruded hair ce

85 eraction of the GAS capsule with CD44 opened intercellular junctions and promoted tissue penetration

86 et formation, a polarized network of nascent intercellular junctions and radial actin cables assemble

87 VCAM-1 increased cortical actin filaments at intercellular junctions and reduced stress fibers across

88 VE)-cadherin, a key regulator of endothelial intercellular junctions and survival.

89 s play an important role in the formation of intercellular junctions and the control of intermembrane

90 n, branching, anastomosis, and maturation of intercellular junctions and the surrounding basement mem

91 ve mutant, disrupted the formation of apical intercellular junctions and their reassembly, impaired t

92 -1 was important for Scribble recruitment to intercellular junctions and TJ reassembly.

93 reduction in the capacity to maintain tight intercellular junctions and to actively reabsorb sodium.

94 agA appears to target H. pylori to host cell intercellular junctions and to disrupt junction-mediated

95 other tube; the two cells adhere and form an intercellular junction, and they become doughnut-shaped

96 s of neighboring cells maintain integrity of intercellular junctions, and alterations in the beta(1)

97 arrier, including keratinocyte cytoskeleton, intercellular junctions, and cell adhesion.

98 bin-induced hyperpermeability, disruption of intercellular junctions, and formation of stress fibers

99 revealed colocalization of Rap1 with JAM1 at intercellular junctions, and knockdown of JAM1 resulted

100 epithelial cells with prominent microvilli, intercellular junctions, and normal chromosomal characte

101 cortex-specifically the actin cytoskeleton, intercellular junctions, and protein complexes that dete

102 Intercellular junctions are crucial for mechanotransduct

103 ertoli cell membrane upon its secretion when intercellular junctions are formed.

104 Epithelial intercellular junctions are important components of the

105 s the presence of specialized low-resistance intercellular junctions as found in other embryos and nu

106 ation, can trigger DSG-2-mediated opening of intercellular junctions as shown by studies with recombi

107 Cadherin-mediated intercellular junctions as well as focal adhesions were

108 ent through a profound redistribution of the intercellular junctions, as well as recruitment and asse

109 determine the effects of EGFR inhibition on intercellular junction assembly and adhesion in oral squ

110 entral facet of organogenesis that relies on intercellular junction assembly to create functionally d

111 e Triton X-100 insoluble cytoskeleton during intercellular junction assembly, prior treatment with 10

112 n a Madin-Darby canine kidney cell model for intercellular junction assembly, TG treatment inhibited

113 and E-cadherin failed to redistribute to the intercellular junctions; assembly of the apical F-actin

114 anization at the SC cell cortex and promotes intercellular junctions at the level of the inner wall o

115 ing the molecular components of the podocyte intercellular junction, because several of these compone

116 defect-driven extrusion mechanism depends on intercellular junctions, because the weakening of cell-c

117 receptors have been shown to cluster at the intercellular junction between a B cell and an antigen-p

118 rn to a more "normal" localization at mainly intercellular junctions between intestinal epithelial ce

119 lular N-cadherin was accumulated in bands at intercellular junctions between SCs and was clustered at

120 tn/plakophilin family proteins interact with intercellular junction binding partners to differentiall

121 on required for blastocoel formation include intercellular junction biogenesis and a directed ion tra

122 c calcium alone is not sufficient for normal intercellular junction biogenesis if intracellular store

123 which increased the component attributed to intercellular junctions but not sarcoplasmic resistivity

124 show that EGFR inhibition stabilizes Dsg2 at intercellular junctions by interfering with its accumula

125 s whose role could be essential to stabilize intercellular junctions by shifting cadherin clusters fr

126 and inhibited the disruption of endothelial intercellular junctions by the IL-2RVE-cadcyto mutant.

127 Adherens junctions (AJs) are the major intercellular junctions by which cells sense and exert m

128 receptors and ligands form a pattern in the intercellular junction called the immunological synapse,

129 d desmocollins, make up the adhesive core of intercellular junctions called desmosomes.

130 ll scattering encompasses the dissolution of intercellular junctions, cell-cell dissociation, cell sp

131 nbeta is essential for the redistribution of intercellular junction components from the lateral punct

132 crest cells and its ability to down-regulate intercellular junctions components.

133 do not form desmosomes, they possess unusual intercellular junctions composed of DP, PG and VE-cadher

134 Accordingly, disruption of intercellular junctions decreased the amount of co-preci

135 F-actin turnover in connecting actomyosin to intercellular junctions, defining a dynamic process requ

136 sive interactions between PMN and epithelial intercellular junctions (desmosomes) that regulate PMN t

137 ion has been given to the possibility of new intercellular junctions developing between cardiocytes w

138 nd patterns (several microns in size) in the intercellular junction during immunological synapse form

139 modeling their cytoskeletal architecture and intercellular junctions during a process known as efface

140 rcalated disk implies a possible role at the intercellular junctions during cardiac ischemia.

141 reorganization of occludin and ZO-1 into the intercellular junctions during the calcium-induced reass

142 ight into p120-catenin's role as guardian of intercellular junction dynamics.

143 In the absence of mXinbeta, the intercellular junctions failed to be restricted to the t

144 However, the onset of defects in intercellular junction formation precedes the onset of e

145 Endothelial cell intercellular junction formation was characterized by im

146 data support the model that during podocyte intercellular junction formation, engagement of the neph

147 se and tensin homolog (PTEN), which impaired intercellular junction formation, prolactin receptor tra

148 egulation of rho-signalling, cytokinesis and intercellular junction formation, we investigated the ef

149 eficient endocardium, indicating a defect in intercellular junction formation.

150 Our data suggest that intercellular junctions formed by neurexins, such as jun

151 ly up-regulated during the redistribution of intercellular junction from the lateral membrane of card

152 influenced the expression of genes encoding intercellular junction (IJ) proteins, whereas the loss o

153 apparatus that can apply mechanical force to intercellular junction in a confluent monolayer of cells

154 e describe the discovery of actin-associated intercellular junctions in Dictyostelium.

155 to DSG2, triggered the transient opening of intercellular junctions in epithelial cells.

156 l dynamics of N-cadherin interactions across intercellular junctions in living cells using a genetica

157 These findings demonstrate the plasticity of intercellular junctions in lymphatics during development

158 es identify PMP22 as an early constituent of intercellular junctions in the developing and mature rat

159 to recent electron microscopical studies of intercellular junctions in the early chick embryo.

160 Synapses are specialized intercellular junctions in which cell adhesion molecules

161 is a transmembrane component of specialized intercellular junctions, including the myocardial interc

162 gulate cell functions directly influenced by intercellular junctions, including the strength of cell

163 g and regulating assembly and disassembly of intercellular junctions is a subject of intensive resear

164 Because dissolution of intercellular junctions is frequently an initial step in

165 t with the host cell membranes that comprise intercellular junctions is not known.

166 Intermediate filament (IF) attachment to intercellular junctions is required for skin and heart i

167 ollins (Dscs), comprise the adhesive core of intercellular junctions known as desmosomes.

168 Alpha(v) and VLA-1 on intercellular junctions may participate in re-establishi

169 tion was not required, indicating that other intercellular junctions mediated this growth regulatory

170 Axl depletion altered expression of intercellular junction molecules increasing cell-cell ad

171 as a cell adhesion molecule at the podocyte intercellular junction necessary for maintaining glomeru

172 uring prostate and mammary involution is the intercellular junction of adjacent secretory epithelium.

173 The tight junction is the most apical intercellular junction of epithelial cells and regulates

174 in homophilic intermolecular interaction at intercellular junctions of apoptotic cells and macrophag

175 on of JAM-A was observed in human RPE and in intercellular junctions of ARPE-19 monolayers.

176 Here T2-TrpRS was shown to bind at intercellular junctions of endothelial cells (ECs).

177 These studies support a role for PMP22 at intercellular junctions of epithelia and may indicate a

178 ing of lymphocyte transmigration through the intercellular junctions of high endothelial venules is l

179 tial cell-cell adhesions and that the stable intercellular junctions of nontransformed epithelial cel

180 Therefore, we studied intercellular junctions of primary human MFs derived fro

181 The intercellular junctions of the endothelial cells of SC w

182 nn cells is unknown, the protein is found at intercellular junctions of various epithelia and endothe

183 v) no orosomucoid molecules are found in the intercellular junctions or at the abluminal exits of int

184 Spirochetes were not observed within intercellular junctions or membrane-bound compartments i

185 properly established and maintained podocyte intercellular junction, or slit diaphragm, is a necessar

186 omerular basement membrane, and the podocyte intercellular junction, or slit diaphragm.

187 Synapses are highly specialized intercellular junctions organized by adhesive and scaffo

188 ed as a key modulator of cadherin-containing intercellular junctions, particularly in tumors that ove

189 uent double-cell calculations then yield the intercellular junction permeability, which is translated

190 by transducing from the specialized podocyte intercellular junction phosphorylation-mediated signals

191 that ECM affects the degree of stability of intercellular junction positioning and the magnitude of

192 CM in the mechanical regulation of cells and intercellular junction positioning.

193 demonstrate that cell intercalations remodel intercellular junctions predominantly between the mediol

194 Desmosomes are adhesive intercellular junctions prominent in the skin and heart.

195 and diseased tissue samples were studied for intercellular junction protein distribution with confoca

196 se data suggest that stiff substrates change intercellular junction protein localization and degradat

197 cell line MIN6, each of which expressed key intercellular junction proteins (connexin-36, E-cadherin

198 tigated the effects of IL-4 on expression of intercellular junction proteins and whether such effects

199 d a C-terminal region that is similar to the intercellular junction proteins dlg-A, PSD95/SAP90, SAP9

200 barrier function and mislocalization of key intercellular junction proteins in the tight junction an

201 ct from those regulating expression of other intercellular junction proteins.

202 Essential roles for FLNA in intercellular junctions provide a mechanism for the dive

203 Because podocyte intercellular junction receptor Nephrin plays a role in

204 ent progress in understanding the role of an intercellular junction referred to as the apical junctio

205 on is primarily regulated by the apical most intercellular junction referred to as the tight junction

206 Intestinal epithelial intercellular junctions regulate barrier properties, and

207 that S1P induced the translocation of Rac to intercellular junctions, resulting in junctional sealing

208 cting components of the specialized podocyte intercellular junction, results in abnormal podocyte mor

209 reased MT density and altered MT dynamics at intercellular junction sites.

210 ondria-rich varicosities and the presence of intercellular junctions suggest that the varicosities ma

211 ellular enclosed lumens with autocellular or intercellular junctions, suggesting that heterogeneous m

212 protein kinases and in proteins specific for intercellular junctions, suggesting that it may be a sig

213 tial pattern of receptors and ligands in the intercellular junction (synapse) is different during thy

214 In addition, withdrawal of cadherins from intercellular junctions temporally precedes the removal

215 HIV to their target CD4(+) cells through an intercellular junction, termed the virologic synapse.

216 at the calyceal membrane resembles a type of intercellular junction that is rare in vertebrates, the

217 The chemical synapse is a specialized intercellular junction that operates nearly autonomously

218 on factor that is regulated by components of intercellular junctions that are affected by cytokines a

219 ing components of the desmosome, specialized intercellular junctions that confer mechanical strength

220 s represents a hyper-adhesive state of these intercellular junctions that is crucial for the maintena

221 Synapses are highly specialized intercellular junctions that mediate the transmission of

222 Desmosomes are critical elements of intercellular junctions; they are punctate structures ma

223 that might interact across the foot process intercellular junction through interactions between Neph

224 Collagen I also disrupted VE-cadherin from intercellular junctions through a Src-dependent mechanis

225 ing the structure and function of epithelial intercellular junctions through direct and indirect mech

226 progression of CCM lesions by destabilizing intercellular junctions through increased cell contracti

227 Rac1 regulate formation of stress fibers and intercellular junctions, thus modulating endothelial mon

228 in intestinal epithelial cells are gated by intercellular junctions (tight junctions and adherens ju

229 nisms that coordinate their trafficking into intercellular junctions to regulate their proper ratio a

230 and switched expression of beta-catenin from intercellular junctions to the nucleus and cytoplasm, in

231 ved from their off-centered position next to intercellular junctions toward extracellular matrix adhe

232 identified immunohistochemically at apparent intercellular junctions was phosphorylated.

233 ted to a defect in the number or assembly of intercellular junctions, we cultured Hailey-Hailey disea

234 thin the left ventricle appeared normal, but intercellular junctions were ill-formed or absent, consi

235 tosols of the testis and epididymis when the intercellular junctions were not previously disrupted, s

236 Intercellular junctions were permanently displaced, and

237 redistribution of occludin and ZO-1 from the intercellular junctions were prevented by PP2.

238 or concentrating PECAM-1 at endothelial cell intercellular junctions, where it functions to facilitat

239 Ab) used to treat solid tumors is limited by intercellular junctions which tightly link epithelial tu

240 In coculture, PMFs developed intercellular junctions with ECs and enhanced the format

241 d diminished VE-cadherin and beta-catenin at intercellular junctions, with resultant intercellular ga

242 omain proteins usually localized at sites of intercellular junctions, yet little is known about their