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1 sequence length polymorphic markers in an F2 intercross.
2 F(2) rats generated from an SR/JrHsd x SHRSP intercross.
3 h some unexpected differences from the B x A intercross.
4 geny from an Itgb2(tm1Bay) (PL/J x C57BL/6J) intercross.
5 r's yeast from a multiparent 12th generation intercross.
6 ession data from a cohort of F2 female mouse intercross.
7 ntified in a B6-Tulp1(tm1Pjn/tm1Pjn) x AKR/J intercross.
8 at this block on albumin excretion in an F2 intercross.
9 re accurately than is possible with standard intercrosses.
10 re generated from Aqp11 +/sjds and Aqp11 +/- intercrosses.
11 e 2 congenic strains and three additional F2 intercrosses.
12 correlated with body weight in two of the F2 intercrosses.
13 to analyze individual embryos from Asah1 +/- intercrosses.
14 pressure QTLs detected in equivalent genetic intercrosses.
15 ood pressure QTLs in equivalent (Dahl S x R)-intercrosses.
16 ygous offspring were observed from PINCH1+/- intercrosses.
17 more than do conventional backcrosses and F2 intercrosses.
18 sis occurs in the F2 generation following F1 intercrosses.
19 allelic chimeric mice without further strain intercrossing.
20 utcrossing to C57BL/10J, and backcrossing or intercrossing.
23 ncreasingly complex genetic structure: an F2 intercross, a heterogeneous stock (HS) formed by crossin
25 te-selective Smad2/Smad3 double knockouts by intercrossing AlbCre/Smad2(f/f) (S2HeKO) and Smad3-defic
26 expression between sexes, and the use of an intercross allowed analysis of the genetic control of se
27 e through application to a set of four mouse intercrosses among five inbred strains, with data on HDL
29 linkage analyses on the progeny of a B6CBAF1 intercross and a CBAxB6CBAF1 backcross were performed.
30 ved (avg. spacing 1.77 cM) in a single large intercross and anchored in the rat genomic sequence (avg
32 g chromosomes with no significant QTL in the intercross and, in some cases (CSS-1, CSS-17), effects t
33 status of suckling offspring from LFKO(-/-) intercrosses and from wild-type (WT) intercrosses showed
34 arbitrary sequence of selfing, backcrossing, intercrossing and haploid-doubling steps that includes m
35 on as new allelic combinations arose through intercrossing and inbreeding to create new stable geneti
37 the major loci previously identified in this intercross, and with SSLPs covering chromosomes 12 and 1
39 clinically affected are 90% greater for F(2) intercross animals injected in the summercompared to tho
40 ock-out, and knock-in mouse models and their intercrosses are more recent developments that mirror de
42 generated from G alpha(12)+/- G alpha(13)+/- intercrosses, at least one intact G alpha(12) allele is
43 using C57Bl/6 (B6), 129S6/SvEvTac (129), and intercross (B6 x 129)F2 mice on a low- or high-fat diet.
46 d a humanized mouse model of HD, Hu97/18, by intercrossing BACHD and YAC18 mice with knockout of the
48 bility locus on chromosome 19 revealed in an intercross between atherosclerosis-susceptible C57BL6 an
49 ale F(2) mice (n=266) were generated from an intercross between B6.Apoe(-/-) and BALB.Apoe(-/-) mice
50 HC) was performed in wan/wan mice from an F2 intercross between C3H/HeJ(+/wan) and CAST/Ei(+/+) F1 hy
51 FeJ strain, F2 Eya1(bor/bor) mutants from an intercross between C3HeB/FeJ-Eya1(bor/+) and C57BL/6J sh
56 somatic tissues of 334 mice derived from an intercross between inbred mouse strains C57BL/6J and C3H
57 inants and mechanisms underlying MetS, an F2 intercross between Lyon hypertensive and Lyon normotensi
58 cross with QTL identified in a previous F(2) intercross between M. m. musculus and M. m. domesticus a
59 uivalent to the Kauai population-an advanced intercross between Red Junglefowl and domestic layer bir
61 t locus (QTL) analysis of schooling in an F2 intercross between strongly schooling marine and weakly
62 and validation of network connections: an F2 intercross between the C57BL/6 J and C3H/HeJ mouse strai
63 position traits in the F(3) generation of an intercross between the Large (LG/J) and Small (SM/J) inb
66 titative trait locus (QTL) analysis using an intercross between the two strains carrying the apoE-/-
70 mice in the F(2) generation produced from an intercross between two inbred strains (C57BL/6J and AKR/
72 solation in house mice, we conducted an F(2) intercross between wild-derived inbred strains from Mus
73 key reproductive barrier, we conducted an F2 intercross between wild-derived inbred strains from two
74 veying viability of Egfrtm1Mag mutants using intercrosses between 129S6/SvEvTAC-Egfrtm1Mag and nine S
78 c linkage maps constructed from experimental intercrosses between closely related house mouse subspec
83 on-complementation of aganglionosis in mouse intercrosses between Ret null and the Ednrb hypomorphic
84 nduced pituitary tumorigenesis in reciprocal intercrosses between the genetically related ACI and Cop
85 ote mutations that reduce the probability of intercrossing between populations carrying different rea
89 found among progeny of A1cf and Ago2 mutant intercrosses but not in backcrosses and without fetal lo
90 assic complement pathway in atherogenesis by intercrossing C1q-deficient mice (C1qa-/-) with low-dens
91 through only four (backcross case) or nine (intercross case) independent standard normal random vari
93 d into a single strain by "endoreduplication intercross." Chemically synthesized genomes like Sc2.0 a
96 fied by other network analyses of this mouse intercross data-set, but all have been previously associ
97 tal parasite infections of advanced mosquito intercrosses demonstrated a strong association between t
98 chromosome 19 in a leptin-deficient obese F2 intercross derived from C57BL/6 (B6) and BTBR T+ tf/J (B
100 MHC genes controlling EBA susceptibility, we intercrossed EBA-susceptible MRL/MpJ with EBA-resistant
101 In this article, motivated by a mosquito intercross experiment involving two selected lines that
102 es are further illustrated with data from an intercross experiment to identify QTL contributing to va
104 gly, although diabetes was evident in the F1 intercross expressing rat insulin promoter (RIP)-TNF, of
105 The AR trial phenotype of BALB/cJ x SWR/J intercross F(1) and F(2) mice was consistent with BALB/c
107 9(+/-) mice were generated, but heterozygous intercrosses failed to yield Mrad9(-/-) pups, since embr
109 specks revealed a compact network of highly intercrossed filaments, whereas pyrin domain (PYD) or ca
110 to hepcidin independently of each other, we intercrossed Hjv(-/-) and Bmp6(-/-) mice and compared th
111 sis were determined in C57BL/6J, BALB/cJ, F1 intercross identical with C57BL/6J X 129S3/SvIM, and 129
112 s analysis performed on F2 C57; Eln(+/-)x129 intercrosses identified highly significant peaks on chro
113 onents of this autoimmune disorder, we first intercrossed IL-2-deficient mice with mice lacking CD28
114 binant inbred lines derived from an advanced intercross, in which multiple generations of mating have
117 ng power calculations for backcross and F(2) intercross incorporating selective genotyping and marker
118 uantitative trait locus (QTL) analysis of an intercross involving the inbred mouse strains NZB/BlNJ a
119 he JNK2 isoform in metabolic homeostasis, we intercrossed Jnk1(-/-) and Jnk2(-/-) mice and examined b
120 n this family segregated either in 1:2:1 (F2 intercross-like segregation) or 1:1 ratio (backcross-lik
122 econd was the 10th generation of an advanced intercross line (AIL) derived from a broiler-layer cross
123 in mice, we used a 34th generation advanced intercross line (AIL) derived from two inbred strains (S
124 We generated a large (n = 815) advanced intercross line of mice (G(4)) derived from a line selec
126 position in a large (n = 645) mouse advanced intercross line originating from a cross between C57BL/6
127 n of this four-way autoimmune-prone advanced intercross line were immunized with a fragment of murine
131 ly developed F(11) generation mouse advanced intercross lines (AIL) to fine map Pas1-3 quantitative t
134 derived from inbred lines, such as advanced intercross lines and heterogeneous stocks, can be used t
135 is thaliana (multiparent advanced generation intercross lines) in controlled conditions simulating fo
136 lectron transfer dissociation (ETD)-MS/MS of intercross-linked peptides (two peptides connected with
139 sions of the multiparent advanced generation intercross (MAGIC) population showed that significant na
140 al stiffness in six-week old F2 (Dahl S x R)-intercross male and female rats characterized for abdomi
142 groups have developed multi-parent advanced intercross mapping panels in different model organisms i
147 er loss of Mbd2 increases lymphomagenesis by intercrossing Mbd2 deficient mice with p53 deficient and
148 were found to be different in female BS x BS intercross mice as compared with females from the three
150 ion restricted cohorts of (B10.S x SJL/J) F2 intercross mice in an effort to identify such linkages.
151 n the susceptibility of (B10.S x SJL/J) F(2) intercross mice to experimental allergic encephalomyelit
152 s deleted in macrophages and neutrophils, we intercrossed mice carrying a loxP-flanked (floxed) IL-4R
155 that were preserved in the iWAT of B6x129 F1-intercrossed mice, with an imbalance favoring the 129-de
156 ficient) CaR(-/-) mice (Pth(-/-)CaR(-/-)) by intercrossing mice heterozygous for the null CaR allele
159 ogy was rescued and viable mice generated by intercrossing MRTF-B mutants with mice expressing Cre re
161 were detected in the F(2) generation of the intercross (n = 510), where no maternal genetic effect v
162 rive from 8 founder inbred strains by serial intercrossing (n>60), resulting in fine-grained genetic
163 atically pair the recombinant gametes of two intercrossed natural genomes into an array of diploid hy
166 hscy, 1,160 F(2) mice were produced from an intercross of (C57BL/6-hscy x CAST/EiJ) F(1) hybrids, an
168 ls could also be recovered following a blind intercross of G1 progeny, yielding several new white-eye
170 ns affecting mouse skeletal morphology in an intercross of LG/J and SM/J inbred strains (N = 1040), u
171 our methods to data on gut length in a large intercross of mice carrying the Sox10Dom mutation, a mod
173 congenic WF.iddm4 rats and report that in an intercross of N5 generation WF.iddm4 rats, approximately
175 a quantitative trait locus analysis using an intercross of PERA/Ei and I/LnJ inbred strains of mice.
176 otyped >3100 hearts from a second-generation intercross of the inbred mouse strains C57BL/6 and FVB/N
178 F(3) population of mice originating from an intercross of the LG/J (Large) and SM/J (Small) inbred s
179 arly growth in mice using a three-generation intercross of the Small (SM/J) and Large (LG/J) inbred m
180 nic mouse strains by performing a reciprocal intercross of the strains HcB-8 and HcB-23, phenotyped f
185 rabidopsis thaliana individuals derived from intercrosses of 30 parents in a half diallel mating sche
186 apoB-27.6 homozygotes (Apob(27.6/27.6)) from intercrosses of Apob(27.6/+) was 7-fold lower than that
187 Homozygous null mice were produced from intercrosses of heterozygous null mice at the expected M
191 rdbp(+/-)) mice are fertile and healthy, but intercrosses of Tardbp(+/-) mice yielded no viable homoz
192 Interval mapping in the F(2) generation from intercrosses of the LG/J and SM/J strains revealed 33 QT
202 imately 30% smaller than that from GPR4(+/+) intercrosses on N3 and N5 C57BL/6 genetic backgrounds.
204 ) is a newly developed multifounder advanced intercross panel consisting of >1600 recombinant inbred
205 om the same parental cross: the IBM advanced intercross population and a conventional recombinant inb
206 gene expression data from an MRL/MpJ x SM/J intercross population and predicted a previously unchara
207 e Panel (DGRP) and a large outbred, advanced intercross population derived from 40 DGRP lines (Flylan
208 ative trait locus GWA on an outbred advanced intercross population derived from extreme DGRP lines, a
209 squito Aedes albopictus and examined an F(1) intercross population for quantitative trait loci (QTL)
210 e mandibular molars in house mice from an F2 intercross population generated from crossing the Large
211 he DGRP and a DGRP-derived outbred, advanced intercross population identified candidate genes and gen
213 otypes derived from a multiparental advanced-intercross population, mapping three moderate-effect loc
217 eference Panel (DGRP) and replicate advanced intercross populations derived from the most and least a
218 thanol/sucrose in the F2 offspring of a B6D2 intercross positively correlates with Ucn immunoreactivi
221 n effects influence EAE, using reciprocal F2 intercross progeny generated between EAE-susceptible SJL
223 lionosis as a quantitative trait in Sox10Dom intercross progeny to investigate the contribution of st
227 random mating, we constructed a new advanced intercross recombinant inbred line (RIL) population deri
228 ted B73 x Mo17 (IBM) population, an advanced intercross recombinant inbred line population derived fr
230 t of early 2-cell embryos from the Asah1 +/- intercrosses rescued Asah1-/- embryos, and enabled their
231 tlSl-20J mice display a white belly spot and intercrossing results in an embryonic lethal phenotype i
236 r 150 offspring or embryos from heterozygous intercrosses revealed an absence of Asah1(-/-) individua
238 be a new approach, called recombinant inbred intercross (RIX) mapping, that extends the power of reco
240 er, total genome-analysis of an F2[Dahl RxS]-intercross selected for contrasting parental strain susc
241 KO(-/-) intercrosses and from wild-type (WT) intercrosses showed that lactoferrin is not essential fo
243 the design and analysis of traditional F(2) intercross studies allows high-confidence prediction of
246 Our inability to predict the results of CSS intercrosses suggests that additional complexity will be
252 the chromosome 10 locus in F2 mice from this intercross, the observations now reported suggest that p
253 research in these two areas and propose that intercrossing them and increasing funding to guide resea
255 ertional mutagenesis screen was performed by intercrossing these mice with those carrying a Sleeping
257 finding significant differences in RD, an F1 intercross to determine rd3 QTLs that influence this inh
259 6.NODc1t mice carrying Idd5 were crossed and intercrossed to generate a C57BL/6.NODc3.NODc1t mouse li
260 and fibromodulin-null heterozygous mice were intercrossed to obtain wild-type (Lum(+/+)Fmod(+/+)), lu
261 The late-generation Tert(+/-) mice were intercrossed to produce genotypically wild-type Tert(+/+
262 backcrosses produced N10F1 rats, which were intercrossed to produce rats that were homozygous for GH
263 x 129)F1 x 129 backcross 1 mice, which were intercrossed to select for homozygosity of particular re
265 ompared a classical intercross and three CSS intercrosses to examine the genetic architecture underly
266 plications have extended beyond experimental intercrosses to outbred populations by exploiting long-r
267 nase using biolistics, lentivirus or genetic intercrosses triggered heterologous expression of TRPV1
269 t consists of 32 BXD strains of mice made by intercrossing two progenitor strains--C57BL/6J and DBA/2
270 ltiple generations, and the breeding scheme (intercrossing vs. outcrossing) drastically affected the
271 thyroidism-induced hearing impairment, an F1 intercross was generated between DW/J-Pou1f1dw/+ carrier
274 eny from a CAST.B6 Mom1(R/S) x B6 Apc(Min/+) intercross were 110 or 200 days of age and screened for
275 mice from a B6-Tulp1(tm1Pjn/tm1Pjn) x AKR/J intercross were genotyped with a panel of single nucleot
279 Offspring of LSL-KRAS(G12D) x PDX-1-Cre intercrosses were randomly allocated to a diet supplemen
280 and linkage analysis in a large F2(DA x PVG) intercross, which identified quantitative trait loci reg
281 erneurons evident in NCAM-EC transgenic mice intercrossed with a reporter line expressing green fluor
282 Floxed beta-catenin (exons 2-6) mice were intercrossed with Albumin-Cre recombinase transgenic mic
285 report here that when Foxo1(KR/KR) mice are intercrossed with low density lipoprotein receptor knock
286 rsion of tcfap2a which has subsequently been intercrossed with mice expressing Cre recombinase under
287 ment in vivo, TgE-LMP2A-transgenic mice were intercrossed with mice expressing loxP-flanked Notch1 ge
288 homozygous for a conditional Apc allele were intercrossed with mice transgenic for Cre recombinase un
290 al cells (LPCs; IKKalpha/beta(LPC-KO) ) were intercrossed with RIPK1(LPC-KO) or RIPK3(-/-) mice to ex
291 54) exhibit a mild disorder, whereas animals intercrossed with SJL/J mice (F1.Q54) have a severe phen
293 of another CD1-defective strain, as well as intercrosses with C57BL/6 mice, indicated that the impai
294 PPP family phosphatases (e.g. PP2A and PP4), intercrosses with mouse lines that ubiquitously express
296 ion of this gene in any tissue of choice, by intercrossing with mice in which Cre-recombinase express
298 ow generated a companion model, Hu128/21, by intercrossing YAC128 and BAC21 mice on the Hdh-/- backgr
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