ライフサイエンスコーパス: interferon-stimulated gene

1 IV infection, consistent with its role as an interferon-stimulated gene.

2 eral other PML-NB proteins, is encoded by an interferon-stimulated gene.

3 ation while simultaneously activating type I interferon-stimulated genes.

4 STAT2 phosphorylation and the expression of interferon-stimulated genes.

5 local antiviral states through expression of interferon-stimulated genes.

6 The 30 upregulated genes included 25 interferon-stimulated genes.

7 shown that ribavirin increases induction of interferon-stimulated genes.

8 ted genes, and block antiviral activities of interferon-stimulated genes.

9 pathway, and to interfere with induction of interferon-stimulated genes.

10 regulatory factors (IRFs), which upregulate interferon-stimulated genes.

11 facilitates the expression of interferon and interferon-stimulated genes.

12 y was associated with elevated expression of interferon-stimulated genes.

13 pectedly, both groups were also enriched for interferon-stimulated genes.

14 recruit RNA polymerase II to the promoter of interferon-stimulated genes.

15 h d109 induced the expression of a number of interferon-stimulated genes.

16 CP0, d106, also resulted in the induction of interferon-stimulated genes.

17 ing it as a positive regulator of alpha/beta interferon-stimulated genes.

18 nd initiation of mRNA translation of type II interferon-stimulated genes.

19 ed synthesis of IFN-beta and upregulation of interferon-stimulated genes.

20 tiviral mechanism, without expression of the interferon-stimulated genes.

21 downregulates mRNA levels of type I IFN and interferon-stimulated genes.

22 cted mice revealed the induction of multiple interferon-stimulated genes.

23 the expression of type I IFNs and antiviral interferon-stimulated genes.

24 ing to enhance the expression of a subset of interferon-stimulated genes.

25 n from highly regulated genes, including the interferon-stimulated genes.

26 We report that the protein encoded by interferon stimulated gene 12 (ISG12), is a novel intera

27 Interferon stimulated gene 15 (ISG15) is a ubiquitin-lik

28 The signature's genes are: Interferon Stimulated Gene 15 (ISG15), Interleukin 16 (I

29 n-mediated transcriptional activation of the interferon-stimulated gene 15 (ISG 15) promoter, and the

30 eport that vIRF1 interacts with the cellular interferon-stimulated gene 15 (ISG15) E3 ligase, HERC5,

31 This report reveals that interferon-stimulated gene 15 (ISG15) mitigates MNV-1 re

32 on of the oncogenic Kirsten-Ras (Ki-Ras) and interferon-stimulated gene 15 (ISG15) pathways is common

33 Accumulation of the interferon-stimulated gene 15 (ISG15) protein product, w

34 ce deficient in free and conjugated forms of interferon-stimulated gene 15 (ISG15) revealed that ISG1

35 virus replication through expression of the interferon-stimulated gene 15 (ISG15), a dimer homologue

36 We investigated interferon-stimulated gene 15 (ISG15), a poorly understo

37 virus (CCHFV), to cleave the Ub-like protein interferon-stimulated gene 15 (ISG15), a protein involve

38 s to coexpress PLpro and a substrate, murine interferon-stimulated gene 15 (ISG15), and found that PL

39 approach, we identified a ubiquitin homolog, interferon-stimulated gene 15 (ISG15), as having antivir

40 Cellular activation induced expression of interferon-stimulated gene 15 (ISG15), tripartite motif

41 FN-alpha/beta]) stimulates the expression of interferon-stimulated gene 15 (ISG15), which encodes a u

42 We report three genes (ISG15 [interferon-stimulated gene 15 kd], DSP [Desmoplakin], an

43 lpha- or IFNgamma-inducible proteins (ISG15 (interferon-stimulated gene 15) and CXCL10) that mediate

44 t conjugation of the ubiquitin-like species, interferon-stimulated gene, 15-kDa protein (ISG15), also

45 cluding computational docking studies and an interferon-stimulated gene 54 (ISG54)-luciferase reporte

46 The interferon-stimulated gene 56 (ISG56) family is induced

47 upregulation of IRF3 primary response genes (interferon-stimulated gene 56 [ISG56], beta IFN [IFN-bet

48 ol 25-hydroxylase (CH25H) is expressed as an interferon-stimulated gene and mediates antiviral activi

49 virus blocked the transcription of multiple interferon-stimulated genes and also downregulated a net

50 Trisomy 21 cells show increased induction of interferon-stimulated genes and decreased expression of

51 that the transcription factor PLZF activates interferon-stimulated genes and facilitates natural kill

52 including the induction of a large number of interferon-stimulated genes and histological evidence of

53 ranscripts in expression of TNF-alpha, other interferon-stimulated genes and induction of apoptosis.

54 pigenomic changes and augments expression of interferon-stimulated genes and ligands for multiple T c

55 The expression of interferon-stimulated genes and selected mediators were

56 ed by virus than are several other classical interferon-stimulated genes and that viral induction of

57 mice exhibited a defect in the expression of interferon-stimulated genes and were unable to clear the

58 ability to activate STAT1, the expression of interferon stimulated genes, and ultimately to the anti-

59 rt Jak-STAT signaling to limit expression of interferon-stimulated genes, and block antiviral activit

60 downregulating the translation of antiviral interferon-stimulated genes, and by co-opting SG protein

61 In MDMs, viperin was the most up-regulated interferon-stimulated genes, and it significantly inhibi

62 y be involved in transcription repression of interferon-stimulated genes, and its association with se

63 ic cells, to distinct expression patterns of interferon-stimulated genes, and to the expression of th

64 Vitamin D related and interferon stimulated genes are good candidates as they

65 NAi components and homologs of antiviral and interferon-stimulated genes are also dsRNA-activated gen

66 First, the pretreatment level of interferon-stimulated genes as well as genetic determina

67 iptional induction of a subset of alpha/beta interferon-stimulated genes by a pathway distinct from t

68 The induction of interferon-stimulated genes by d109 could also be inhibi

69 ding induction of inflammatory cytokines and interferon-stimulated genes characteristic of innate imm

70 G37S mutation led to increased expression of interferon-stimulated genes dependent on the cGAS-STING

71 ' ability to express type I IFN and activate interferon-stimulated genes during subsequent infection

72 cases identified the limited upregulation of interferon-stimulated genes early in infection in severe

73 Consistently, transcription of interferon-stimulated genes (eg, OAS1, ISG15, Mx1; each

74 A novel interferon-stimulated gene encoding a 43-kDa ubiquitin-s

75 increases in the intrahepatic transcripts of interferon-stimulated genes, even in animals exhibiting

76 e that acted on host histone H2BJ to promote interferon-stimulated gene expression and on viral 3C pr

77 edia from HPAIV-infected cells, p38 controls interferon-stimulated gene expression by coregulating ST

78 expression was necessary for high levels of interferon-stimulated gene expression in HEL cells.

79 A striking absence of interferon-stimulated gene expression in patients with K

80 ngle cell transcriptomics, we establish that interferon-stimulated gene expression is induced in micr

81 Interferon-stimulated gene expression is mediated by tra

82 nterferon regulatory factor 3 activation and interferon-stimulated gene expression, but the requireme

83 aramyxovirus infection to activate IRF-3 and interferon-stimulated gene expression, but they failed t

84 d the following pharmacodynamics parameters: interferon-stimulated gene expression, cytokine and chem

85 proach revealed a link between: 1) increased interferon-stimulated gene expression, IFNalpha levels,

86 MEM173)-IRF3-dependent signalling to elevate interferon-stimulated gene expression, potentiate type I

87 ctors in vivo is to closely monitor signs of interferon-stimulated gene expression, since a narrow wi

88 in a novel role in the regulation of type 1 interferon-stimulated gene expression.

89 d CXCL10, as well as type I interferons, and interferon-stimulated gene expression.

90 at hPNPase(old-35) is a direct target of the interferon stimulated gene factor 3 (ISGF3) complex.

91 ements, including the Stat components of the interferon-stimulated gene factor 3 (ISGF-3).

92 in regulating IFN-dependent STAT activation, interferon-stimulated gene factor 3 (ISGF3) and c-sis-in

93 ponse element site in the first intron binds interferon-stimulated gene factor 3 (ISGF3) and confers

94 Although IFN-I signal via the interferon-stimulated gene factor 3 (ISGF3) complex cons

95 ever, IFN alpha stimulation failed to induce interferon-stimulated gene factor 3 (ISGF3) complex form

96 ormation of the transcription factor complex interferon-stimulated gene factor 3 (ISGF3) in response

97 tact Stat2 site did not lead to induction of interferon-stimulated gene factor 3 (ISGF3) or an antivi

98 he canonical type I IFN transcription factor interferon-stimulated gene factor 3 (ISGF3) was necessar

99 f mediating interferon alpha- (IFNalpha) and interferon-stimulated gene factor 3 (ISGF3)-specific tra

100 ng in activation of the transcription factor interferon-stimulated gene factor 3 (ISGF3).

101 ngs imply that type I IFN signaling [through interferon-stimulated gene factor 3 (ISGF3)] is surprisi

102 (STAT1) and STAT2, which form heterotrimers (interferon-stimulated gene factor 3 [ISGF3]) with interf

103 ted in the absence of IKKepsilon because the interferon-stimulated gene factor 3 complex (ISGF3) does

104 e I infection also inhibits IFN-beta-induced interferon-stimulated gene factor 3-mediated gene expres

105 roteins that participate in the formation of interferon-stimulated gene factor 3.

106 n-regulatory factor 1 (IRF-1), also known as interferon-stimulated-gene factor 2 (ISGF-2), is synergi

107 ittle is known about the mechanisms by which interferon-stimulated genes function to inhibit viral re

108 MMR-related febrile seizures, harboring the interferon-stimulated gene IFI44L (rs273259: P = 5.9 x 1

109 gulated expression of type I interferons and interferon-stimulated genes in both the duodenum and lun

110 ments provoked lower levels of expression of interferon-stimulated genes in cells than wild type-deri

111 HIV-1(BaL) induced a subset of interferon-stimulated genes in monocyte-derived macropha

112 tance protein A in the skin and induction of interferon-stimulated genes in peripheral blood cells de

113 pe STAT2 in mediating the expression of many interferon-stimulated genes, in protecting cells against

114 ase state is associated with upregulation of interferon-stimulated genes, indicating a possible role

115 Among the most highly induced is a set of interferon-stimulated genes, indicative of a type I inte

116 rent MOIs are correlated with differences in interferon-stimulated gene induction, indicating that th

117 ection that can also be enhanced by blocking interferon-stimulated gene induction.

118 rus concentrations also resulted in distinct interferon-stimulated gene induction.

119 Here, we examine the influence of the interferon-stimulated gene IRAV (FLJ11286) on dengue vir

120 Whether the expression of interferon-stimulated genes is a marker of ongoing virem

121 compound 54 effectively induced a transient interferon stimulated gene (ISG) response in mice and cy

122 S-CoV with aberrant cytokine, chemokine, and Interferon Stimulated Gene (ISG) responses in patients p

123 in humanized mice and modelled intrahepatic interferon stimulated gene (ISG) responses.

124 Interferon-stimulated gene (ISG) 15 mediates antiviral r

125 Human myxovirus resistance 2 (MX2/MXB) is an interferon-stimulated gene (ISG) and was recently identi

126 antiviral signaling protein (MAVS)/TBK1/IRF3/interferon-stimulated gene (ISG) axis, causing either an

127 type I IFN receptor IFNAR exhibited impaired interferon-stimulated gene (ISG) expression and, in the

128 Viral kinetics and interferon-stimulated gene (ISG) expression in periphera

129 -infected chimpanzees in whose livers type I interferon-stimulated gene (ISG) expression is strongly

130 served in females are associated with higher interferon-stimulated gene (ISG) expression levels in T

131 directs alpha/beta interferon production and interferon-stimulated gene (ISG) expression, which limit

132 ytomegalovirus (CMV) is a potent elicitor of interferon-stimulated gene (ISG) expression.

133 Cholesterol 25-hydroxylase (CH25H) as an interferon-stimulated gene (ISG) has recently been shown

134 ce, we defined the antiviral function of the interferon-stimulated gene (ISG) Ifit2 in limiting infec

135 resent evidence that MHV infection can delay interferon-stimulated gene (ISG) induction mediated by b

136 III IFNs differed greatly in their level of interferon-stimulated gene (ISG) induction with a clearl

137 ody, we studied the role of virion fusion in interferon-stimulated gene (ISG) induction.

138 Interferon-stimulated gene (ISG) products take on a numb

139 al model of disease, identifying significant interferon-stimulated gene (ISG) transcript upregulation

140 UL46-expressing cell lines did not activate interferon-stimulated gene (ISG) transcription following

141 with tetratricopeptide repeats 2 (Ifit2), an interferon-stimulated gene (ISG) with possible RNA-bindi

142 ruses did not evoke a detectable IFN-beta or interferon-stimulated gene (ISG; MX1, oligoadenylate syn

143 replication, and assayed host expression of interferon-stimulated genes (ISG) by microarray and reve

144 us-induced expression of IFN-beta, IRF-7 (an interferon-stimulated gene [ISG] that further induces IF

145 by MKK7-JNK1beta included a number of known interferon-stimulated genes (ISG12, ISG15, IGTP, and GTP

146 We demonstrate that the interferon-stimulated gene ISG15 is induced by p53 and t

147 in-activating enzyme (UBE1L) associates with interferon-stimulated gene ISG15 that binds and represse

148 emonstrates that expression of a single host interferon-stimulated gene, ISG15, restricts HCMV replic

149 hepatitis C (CHC) have ongoing expression of interferon stimulated genes (ISGs) in the liver.

150 The induced IFNs activate many interferon stimulated genes (ISGs) that have direct anti

151 feron alpha (IFN-alpha) and the induction of interferon stimulated genes (ISGs), as well as the expre

152 induced steady increases in levels of known interferon stimulated genes (ISGs), whereas IFN-alpha IS

153 between IFN-alpha and IL28B stimulation for interferon stimulated genes (ISGs).

154 4 hours before each IFN injection to measure interferon stimulated genes (ISGs).

155 Interferon-stimulated genes (ISGs) act in concert to pro

156 Activation of cellular interferon-stimulated genes (ISGs) after infection with

157 lture system to inducibly express individual interferon-stimulated genes (ISGs) and determined their

158 ction of type I interferons, which activates interferon-stimulated genes (ISGs) and directs a multifa

159 nstant includes the coordinate activation of interferon-stimulated genes (ISGs) and immune effector f

160 type specific expression patterns of hepatic interferon-stimulated genes (ISGs) and single nucleotide

161 st response to viral infections, hundreds of interferon-stimulated genes (ISGs) are induced.

162 bsence of virus infection, microRNAs repress interferon-stimulated genes (ISGs) associated with cell

163 The expression of hundreds of interferon-stimulated genes (ISGs) causes the cellular "

164 Interestingly, interferon-stimulated genes (ISGs) encoding proteins suc

165 tetratricopeptide repeats (IFIT), which are interferon-stimulated genes (ISGs) implicated in regulat

166 fibroblast cells activates a large number of interferon-stimulated genes (ISGs) in a viral envelope-c

167 tion of interferons (both type I and II) and interferon-stimulated genes (ISGs) in CH10273.

168 IFN-lambda can induce antiviral interferon-stimulated genes (ISGs) in epithelia, while t

169 sts that ribavirin augments the induction of interferon-stimulated genes (ISGs) in patients treated f

170 Cells express a plethora of interferon-stimulated genes (ISGs) in response to viral

171 ctivated JAK/STAT pathways and expression of interferon-stimulated genes (ISGs) is upregulated.

172 The interferon-stimulated genes (ISGs) ISG56 and ISG54 are s

173 duction of type I IFN, type III IFN, and the interferon-stimulated genes (ISGs) Mx and ISG56 by infec

174 d the resulting up-regulation of hundreds of interferon-stimulated genes (ISGs) provide an immediate

175 a1 (IL-29), IFN-lambda2/3 (IL-28A/B) and the interferon-stimulated genes (ISGs) such as myxovirus res

176 ssion of interferon-alpha/beta and antiviral/interferon-stimulated genes (ISGs) that limit infection.

177 s C virus (HCV) infection, yet the component interferon-stimulated genes (ISGs) that mediate the anti

178 HCMV is known to repurpose the interferon-stimulated genes (ISGs) viperin and tetherin

179 The role of IMPDH and interferon-stimulated genes (ISGs) was investigated in t

180 The expression of six interferon-stimulated genes (ISGs) was measured by quant

181 Known interferon-stimulated genes (ISGs) were induced in treat

182 amma interferon (IFN-gamma) and 16 antiviral interferon-stimulated genes (ISGs) were upregulated 3.1-

183 tiviral effects through upregulation of many interferon-stimulated genes (ISGs) whose protein product

184 we also show that IL-1 can induce one of the interferon-stimulated genes (ISGs), 1-8U, which exhibits

185 in the robust expression of type I IFNs and interferon-stimulated genes (ISGs), a strong activation

186 lpha induces the expression of more than 300 interferon-stimulated genes (ISGs), and this blunts infl

187 and IFNbeta genes, as well as of a number of interferon-stimulated genes (ISGs), as a result of viral

188 restriction factors against CSFV, including interferon-stimulated genes (ISGs), have been characteri

189 he expression of type I interferon (IFN) and interferon-stimulated genes (ISGs), including a variety

190 he expression of type I interferon (IFN) and interferon-stimulated genes (ISGs), including a variety

191 e initial transcription of multiple critical interferon-stimulated genes (ISGs), including IFITM3 and

192 ponses and with the up-regulation of several interferon-stimulated genes (ISGs), including those invo

193 the utility of this system, we show that two interferon-stimulated genes (ISGs), ISG20 and tetherin,

194 nterferon response factor 3 (IRF3)-dependent interferon-stimulated genes (ISGs), ISG54 and ISG56, in

195 s associated with intrahepatic expression of interferon-stimulated genes (ISGs), known to influence t

196 al state through upregulation of hundreds of interferon-stimulated genes (ISGs), most of which have u

197 As expected, expression of Rb1 and interferon-stimulated genes (ISGs), plasma soluble CD163

198 from viral infection by inducing hundreds of interferon-stimulated genes (ISGs), some of which encode

199 ants induce moderate levels of expression of interferon-stimulated genes (ISGs), suggesting either th

200 nus can antagonize the antiviral activity of interferon-stimulated genes (ISGs), we pretreated cells

201 esulting in the transcription of hundreds of interferon-stimulated genes (ISGs), which define the ant

202 uced expression of interferon (IFN)-beta and interferon-stimulated genes (ISGs), while knockdown of T

203 TAT1 activation, and diminished induction of interferon-stimulated genes (ISGs).

204 induction of beta interferon (IFN-beta) and interferon-stimulated genes (ISGs).

205 antiviral pathways through the induction of interferon-stimulated genes (ISGs).

206 on of which is required for transcription of interferon-stimulated genes (ISGs).

207 hat mediate this defence are the products of interferon-stimulated genes (ISGs).

208 r, RelA directly regulates a small subset of interferon-stimulated genes (ISGs).

209 is revealed a heightened basal expression of interferon-stimulated genes (ISGs).

210 ables the virus to circumvent the effects of interferon-stimulated genes (ISGs).

211 cytokines, type I interferons, and numerous interferon-stimulated genes (ISGs).

212 or 3 (IRF3), a cofactor for the induction of interferon-stimulated genes (ISGs).

213 to activation of a large number of cellular interferon-stimulated genes (ISGs).

214 which induces the expression of hundreds of interferon-stimulated genes (ISGs).

215 to suppress the mRNA expression of selected interferon-stimulated genes (ISGs).

216 the expression of IFN-gamma and 16 antiviral interferon-stimulated genes (ISGs).

217 ctions by inducing expression of hundreds of interferon-stimulated genes (ISGs).

218 ne responses through the concerted action of interferon-stimulated genes (ISGs).

219 acellular actions of the proteins encoded by interferon-stimulated genes (ISGs); among these are the

220 in granule cell neurons, we identified three interferon-stimulated genes (ISGs; Ifi27, Irg1 and Rsad2

221 led to a relative decrease in expression of interferon-stimulated genes (ISGs; MX1 and IFIT5) and in

222 specific CD8(+) T cells correlated with both interferon-stimulated gene levels in T cells and hepatic

223 Increased expression of interferon-stimulated genes may favor the persistence of

224 ther cytokines and chemokines, and activated interferon-stimulated genes, natural killer cells, and l

225 robust interferon response and induction of interferon-stimulated genes observed during later stages

226 ated the role of the ubiquitin-like modifier interferon-stimulated gene of 15 kDa (ISG15) in the path

227 One interferon-stimulated gene of particular interest was UB

228 not regulate IFN-inducible transcription of interferon-stimulated genes or generation of antiviral r

229 of Toll-like receptor 7 and upregulation of interferon-stimulated genes play a central role.

230 on of phosphorylated STAT1 and the classical interferon-stimulated gene produces MxA and OAS.

231 result, the interface of MERS-CoV and human interferon-stimulated gene product 15 (hISG15) was probe

232 athways through the removal of ubiquitin and interferon-stimulated gene product 15 (ISG15) from targe

233 l modification by ubiquitin (Ub) and Ub-like interferon-stimulated gene product 15 (ISG15) to stabili

234 dification of host proteins by ubiquitin and interferon-stimulated gene product 15 (ISG15), subsequen

235 ugated with either ubiquitin (Ub) or Ub-like interferon-stimulated gene product 15 (ISG15).

236 f alpha and gamma interferons, the antiviral interferon-stimulated gene product 2'-5' oligoadenylate

237 were more sensitive to the expression of the interferon-stimulated gene product IFIT2 than the parent

238 were more sensitive to the expression of the interferon-stimulated gene product IFIT2 than the parent

239 Protein kinase R (PKR), a classical interferon-stimulated gene product, phosphorylates the e

240 E The results of this study demonstrate that interferon-stimulated gene products PARP7, PARP10, and P

241 ich prevents the induction of interferon and interferon-stimulated gene promoters.

242 sults suggest that SAMHD1 is a non-classical interferon-stimulated gene regulated through cell type-d

243 anscription decreased in MDA5(-/-) mice, the interferon-stimulated gene response remained intact.

244 n-specific elements were a time shift of the interferon-stimulated gene response, selective induction

245 protein 1 were quantified as measures of the interferon-stimulated genes response.

246 In search of the interferon-stimulated gene(s) that is responsible for th

247 ects HCV clearance, IFN-lambda3 up-regulates interferon-stimulated genes, similar to IFN-alpha and IF

248 The induced levels of known interferon-stimulated genes such as the 2'5'-oligoadenyl

249 tiviral response measured by upregulation of interferon-stimulated genes, such as CXCL10 and DAI.

250 In a previous screen of putative interferon-stimulated genes, SUN2 was shown to inhibit H

251 xpression of types I and III interferons and interferon-stimulated genes than do cells from children

252 Taking into account the wide range of interferon stimulated genes that may be induced by the S

253 Viperin is an interferon-stimulated gene that exerts antiviral effects

254 transmembrane protein 3 (IFITM3) gene is an interferon-stimulated gene that inhibits the replication

255 he zinc finger antiviral protein (ZAP) is an interferon-stimulated gene that restricts the replicatio

256 ignaling pathways, inducing a vast number of interferon-stimulated genes that are overlapping but dis

257 ly increase the expression of several genes (interferon-stimulated genes) that are known to be strong

258 aling pathways that induce the expression of interferon-stimulated genes; the proteins encoded by the

259 TLR4 can induce both IFNbeta and interferon-stimulated genes through its adapter molecule

260 roducts correlated with the amplification of interferon-stimulated genes to up to 10 times above norm

261 ytokines was correlated with elevated type I interferon-stimulated gene transcripts.

262 ponding MxA and USP18 mRNAs, suggesting that interferon-stimulated gene translation is inhibited in s

263 As also repressed the induction of antiviral interferon-stimulated genes upon IFNalpha- treatment.

264 IL28B acts on interferon-stimulated genes via the JAK-STAT pathway, wh

265 In the liver and brain, expression of interferon-stimulated genes was detected by 1 to 3 h fol

266 I interferon receptor, strong expression of interferon-stimulated genes was observed in the lungs of

267 were normal; however, the early induction of interferon-stimulated genes was selectively and severely

268 By systematic screening using a panel of interferon-stimulated genes we identify two siblings and

269 n effects of each virus on the expression of interferon-stimulated genes were also investigated in A5

270 Many interferon-stimulated genes were detected in the bronchi

271 (IFITM3) messenger RNA (the transcript of an interferon-stimulated gene) were measured in the same he

272 dritic cells, and the expression patterns of interferon-stimulated genes, were most closely linked to

273 city of TRIF/IRF3 signaling and suggest that interferon-stimulated genes, whether induced by IFNbeta

274 ally and significantly enriched for a set of interferon-stimulated genes which on further in silico a

275 These data serve to characterize an interferon-stimulated gene with antiviral activity again

276 Nalpha induces the expression of an array of interferon-stimulated genes within minutes of receptor e

277 and spread in brain cells if not blocked by interferon-stimulated genes within the brain.IMPORTANCE

278 Activating interferon-stimulated genes without the need for prior s