ライフサイエンスコーパス: interindividual

1 dual) and among the bulbs of different mice (interindividual).

2 Interindividual and ethnic variation in glycated hemoglo

3 orticoid receptor gene promoter is linked to interindividual and gender-specific differences in memor

4 d with clearance (P < 0.01), explaining both interindividual and interoccasional variability.

5 Although genetic factors contribute to interindividual and interpopulation variation in reprodu

6 Ten studies that examined interindividual and intraindividual patterns of activity

7 For interindividual comparison, glaucoma patients at various

8 mal eyes (57 subjects) were enrolled for the interindividual comparison.

9 Mean intra- and interindividual CVs were 20% and 25%, respectively.

10 In addition to establishing the interindividual degree of variation within a broad panel

11 ers, but the neurogenetic mechanisms driving interindividual differences are largely unknown.

12 Yet, the mechanisms underlying these interindividual differences are largely unknown.

13 ion differentially drive intraindividual and interindividual differences in altruistic behavior.

14 rsion might provide the functional basis for interindividual differences in behavior and cognition.

15 A compartmental model that allowed for interindividual differences in cis- and all-trans-lycope

16 a better understanding of the mechanisms of interindividual differences in cognition.

17 onship informs about the biological basis of interindividual differences in cognitive control.

18 individuals into 2 distinct groups based on interindividual differences in concentrations of differe

19 EBA); activity in the PMv moreover reflected interindividual differences in congruent arm ownership.

20 al events mediating the relationship between interindividual differences in cortical surface area and

21 control, and recent studies have shown that interindividual differences in dACC anatomy are associat

22 ggesting that quantitating and understanding interindividual differences in DNA repair capacity (DRC)

23 y within the oxytocin gene appear to explain interindividual differences in dopaminergic responses to

24 help to evaluate potential CYP2D6-dependent interindividual differences in drug response in the cont

25 The first-principles model better quantifies interindividual differences in food intake, shows how as

26 ask-based fMRI data, these two DCS predicted interindividual differences in frequency of behavioral l

27 her candidate genes that are associated with interindividual differences in humoral immunity to rubel

28 only during TLR signalling and contribute to interindividual differences in immune response.

29 dy how experience and genetics contribute to interindividual differences in learned song.

30 idual variability in GABA level is linked to interindividual differences in many aspects of visual pe

31 Interindividual differences in many behaviors are partly

32 ) in metallothionein (MT) genes may underlie interindividual differences in mercury biomarker levels.

33 Furthermore, the interindividual differences in methylation seen across t

34 of plasma CK-M and CA-3 revealed changes and interindividual differences in muscle tissue proteome dy

35 sms in HLA-DPB1 are strongly associated with interindividual differences in neutralizing antibody lev

36 h the host genetic background contributes to interindividual differences in other determinants of HIV

37 Interindividual differences in response to diet exist, b

38 However, large interindividual differences in responses to rTMS have be

39 ked activity in the pre-SMA was predicted by interindividual differences in risk-aversion attitudes e

40 These results suggest widespread interindividual differences in RNA stability related to

41 f parietal and occipital cortices related to interindividual differences in size, orientation, and br

42 ect brain development, contributing to shape interindividual differences in stress vulnerability and

43 rks (Delta connectivity lFPN-rFPN) predicted interindividual differences in task performance more acc

44 Interindividual differences in the amplitude of this ele

45 "compensation" for underlying genetic-driven interindividual differences in the baseline chromatin an

46 We found large interindividual differences in the degree of model-based

47 etic and environmental influences explaining interindividual differences in the developmental course

48 Interindividual differences in the effects of reward on

49 ance imaging and tractography, could explain interindividual differences in the effects of rTMS.

50 Single-subject analysis revealed clear interindividual differences in the extension of such per

51 We show that interindividual differences in the extension of the PPS

52 absorbed in the jejunum but with substantial interindividual differences in the extent of absorption.

53 dence also suggests a potential link between interindividual differences in the gut microbiota and va

54 Interindividual differences in the linear change in hype

55 ange in representational similarity predicts interindividual differences in the malleability of subje

56 Strong interindividual differences in the microbial conversion

57 This new evidence hints that interindividual differences in the microbiome may accoun

58 sed on loss aversion with the aim to address interindividual differences in the neural bases of choic

59 Traditionally, interindividual differences in the population are accoun

60 has become clear that there are substantial interindividual differences in the risk of HIV acquisiti

61 Previous work has shown high interindividual differences in the susceptibility to the

62 Capturing interindividual differences in the translated genome wil

63 Moreover, AhR-deficient mice had higher interindividual differences in their microbiome.

64 amyloid biomarker measurements may be due to interindividual differences in total amyloid-beta produc

65 The aim of this study was to elucidate interindividual differences in trans-resveratrol metabol

66 We found large interindividual differences in TSP responses, which were

67 als, and this variability is associated with interindividual differences in visual perception.

68 c proactive interference (PI) contributes to interindividual differences in working memory (WM) capac

69 occur periodically in each brain, or marked interindividual differences that may persist throughout

70 Strong interindividual differences were also observed for rhyth

71 Although interindividual differences were detected, animals prese

72 Are interindividual differences, for example in tract latera

73 In addition, interindividual differences, including genetic variation

74 tive enhancement has neglected the effect of interindividual differences, such as traits, on stimulat

75 Examining interindividual differences, we find the benefit of proa

76 ism by human gut microbiota shows pronounced interindividual differences, which should be taken into

77 n toward the periphery in presence of marked interindividual differences.

78 y explain 18.7% of the variation seen in the interindividual distance of microbial composition.

79 e cards and follow-up samplings, we identify interindividual DNA methylation variation that is presen

80 We show that FM-HCR can measure interindividual DRC differences in a panel of 24 cell li

81 function, which would be expected to affect interindividual drug disposition and response.

82 great degree of interlocus, intertissue, and interindividual epigenetic variation in most of the anal

83 Interindividual epigenetic variation that occurs systemi

84 ective strategy for studying the dynamics of interindividual epigenomic variation in a range of commo

85 Genes exhibiting high interindividual expression variation include disease can

86 ween individuals and its contribution to the interindividual expression variation remain unknown.

87 bodies, suggesting epigenetic regulation of interindividual expression variation.

88 proportion of variance in cancer risk due to interindividual genetic differences) with follow-up via

89 Subtle interindividual genetic variation as well as viral and e

90 understanding and controlling the impact of interindividual gut microbe variability on the dispositi

91 We analyzed this interindividual heterogeneity and provide a predictive m

92 Interindividual heterogeneity in drug response is a cent

93 xtual measures (i.e., the share of the total interindividual heterogeneity in health that appears at

94 gression analyses likely conceal substantial interindividual heterogeneity in postdeployment alcohol-

95 Interindividual heterogeneity in the disease progression

96 in the management of asthma, but substantial interindividual heterogeneity is observed in the respons

97 al blood, with an ultimate goal of examining interindividual heterogeneity of endothelial biology.

98 tients are difficult to interpret because of interindividual heterogeneity, reflecting variations in

99 ples analyzed, and the results revealed high interindividual heterogeneity, with most of the reactivi

100 intraindividual pathological homogeneity and interindividual heterogeneity.

101 activation associated with LV scar with high interindividual heterogeneity.

102 individuals; such variability likely affects interindividual inflammatory/autoimmune disease suscepti

103 nisms might be involved in the regulation of interindividual lipid level variability and thus may con

104 Their interindividual pharmacokinetic variability is remarkabl

105 These loci explained up to 66% of interindividual plasma protein-level variation and, on a

106 amygdala and dorsal putamen activity steered interindividual preferences in competition avoidance and

107 In mice and humans, there is a wide interindividual range in Treg frequency, but little is k

108 For 32 g oil, the interindividual rank order of the chylomicron AUCs was c

109 Accumulating evidence about variable interindividual response to dietary intake of these caro

110 Differences in the interindividual response to dietary intervention could b

111 rol levels in large studies and the observed interindividual response variability may be partially ex

112 In genes presenting interindividual RNA half-life differences, higher coding

113 develop personalized toxicology to determine interindividual susceptibility to adverse drug reactions

114 gate the genetic architecture underlying the interindividual TGP variability, we conducted a genome-w

115 th the magnitude of and molecular causes for interindividual toxicodynamic variability.

116 for subsequent infection and a key event in interindividual transmission.

117 ean, 0.0276 L/hour/kg) showed remarkably low interindividual variability (32.4% coefficient of variat

118 expressed in blood cells with a substantial interindividual variability (seven-fold variation in mRN

119 increases into adulthood and no significant interindividual variability across development, and was

120 Thus, interindividual variability affects the fundamental immu

121 To better understand the interindividual variability associated with the majority

122 model could explain a large fraction of the interindividual variability by variations in the initial

123 gions revealed no changes with age, although interindividual variability decreased with development,

124 Wide interindividual variability exists in response to tissue

125 However, marked interindividual variability exists in the degree to whic

126 Substantial interindividual variability exists in the maximal rate o

127 nformation and models relevant for assessing interindividual variability for application to human hea

128 The genetic contribution to interindividual variability has emerged as a promising a

129 ce from emerging data streams for addressing interindividual variability in a range of decision-makin

130 MED23, Arg1, and AGXT2) associated with the interindividual variability in ADMA, l-arginine, and SDM

131 l was to investigate processes that underlie interindividual variability in age-related changes in th

132 nd one-carbon metabolism in the mechanism of interindividual variability in alcoholic liver injury.

133 The results demonstrate large interindividual variability in alpha-carotene conversion

134 ults reveal a neurogenetic pathway mediating interindividual variability in anticipatory responses to

135 rior parietal, and visual cortices predicted interindividual variability in attentional capacity.

136 ion serial reversal procedure to investigate interindividual variability in behavioral flexibility in

137 ed that genetic variants could contribute to interindividual variability in blood concentrations of t

138 oid signalling pathway may contribute to the interindividual variability in clinical response to ICS

139 erty can be further explored to overcome the interindividual variability in clopidogrel therapy.

140 clinical symptom severity; incorporation of interindividual variability in cognitive impairment asso

141 However, interindividual variability in fecal menaquinone concent

142 ed intake, which is likely mediated via wide interindividual variability in flavonoid absorption and

143 This interindividual variability in GABA level is linked to i

144 uence of GABA raises the question of whether interindividual variability in GABA reflects an overall

145 sponse is important for the understanding of interindividual variability in human pathologies.

146 Here we show that interindividual variability in human visual cortical sur

147 genetics and review the emerging evidence of interindividual variability in humoral and cell-mediated

148 ments using human genotyped livers showed an interindividual variability in hydroxytyrosol formation

149 e TRBV repertoire clearly contributes toward interindividual variability in immune responses and is p

150 archical Gaussian filter model that captures interindividual variability in learning under uncertaint

151 the amygdala and accounts for virtually all interindividual variability in long-term fear memory str

152 We characterized the interindividual variability in lutein bioavailability in

153 at distal regulatory elements may affect the interindividual variability in microRNA expression level

154 The interindividual variability in MTX kinetics had a substa

155 should focus on the mechanisms and levels of interindividual variability in OA response, so that we c

156 or neurocognitive problems, with significant interindividual variability in outcome.

157 We report that interindividual variability in patients' lesions led to

158 timates fail to account for the considerable interindividual variability in pre-clinical risk status.

159 cotherapy for its treatment; however, marked interindividual variability in response and few clinical

160 The interindividual variability in response to brain stimula

161 BI) is a multifactorial pathology with great interindividual variability in response to injury and ou

162 However, significant interindividual variability in risk suggests a role for

163 The human cochlea shows considerable interindividual variability in size and morphology.

164 on within each eye; however, it showed large interindividual variability in size, shape, location, an

165 Here, we examine interindividual variability in skin MC responses to Fcep

166 Interindividual variability in statin exposure in patien

167 Despite high interindividual variability in terms of relative tissue

168 egies with SD OCT that account for the large interindividual variability in the angle between the fov

169 be thought of as a connectome disease, with interindividual variability in the brain's adaptation to

170 modest but independent contributions to the interindividual variability in the capacity to oxidize f

171 Interindividual variability in the dose-dependent associ

172 tification-and extent of characterization-of interindividual variability in the human population.

173 contribution of a self-selected diet to the interindividual variability in the MFO requires further

174 A total of 44.4% of the interindividual variability in the MFO was explained by

175 oscopic gamma frequency may be attributed to interindividual variability in the microscopic architect

176 ain activities together accounted for 81% of interindividual variability in the modulation of movemen

177 There was large interindividual variability in the reductions of LDL-C,

178 These results suggest that interindividual variability in the response of monocytes

179 copic resolution and observed an astonishing interindividual variability in the shape.

180 However, there is substantial interindividual variability in the specificity of these

181 findings provide evidence that, in mammals, interindividual variability in trait anxiety is causally

182 trajectories, and variables that predict any interindividual variability in trajectories.

183 Thus, interindividual variability in ventral striatal presynap

184 and complex metabolic pathways suggest that interindividual variability in vitamin D metabolism may

185 K; however, there is still large unexplained interindividual variability in vitamin K status.

186 A similar proportion of the interindividual variability in warfarin dose is explaine

187 al factors explain approximately half of the interindividual variability in warfarin dose requirement

188 Evaluation of interindividual variability is a challenging step in ris

189 In standard learning models, interindividual variability is often explained by variat

190 lcal length metrics, our data illustrate the interindividual variability of Broca's area homologue in

191 Analysis of scedasticity showed that interindividual variability of DNA methylation increased

192 ns of pharmacokinetic profiles, resulting in interindividual variability of drug toxicity and/or effi

193 We show that interindividual variability of hippocampal volumes in a

194 Little is known about interindividual variability of histone modification leve

195 rm infants; in addition, intraindividual and interindividual variability of human milk protein and en

196 genetics, and cellular heterogeneity on the interindividual variability of immune responses and cons

197 disease, and understanding genetic causes of interindividual variability of immune responses is vital

198 f this meta-analysis was to evaluate: 1) the interindividual variability of reductions in low-density

199 e environmental and genetic contributions to interindividual variability of these biomarkers.

200 al level, for example, in differences in the interindividual variability of these brain volumes relat

201 ular mechanisms as potential explanation for interindividual variability of thiopurine response, we d

202 participants developed algorithms to predict interindividual variability of toxic response from genom

203 Drug RO data showed low interindividual variability per dose (mean RO SD, 2.1%),

204 e, within-subject stability and a remarkable interindividual variability that correlates with functio

205 ility of lutein is assumed to display a high interindividual variability that has been hypothesized t

206 In these data-based models, interindividual variability was quantified by a key para

207 Population pharmacokinetic parameters and interindividual variability were estimated for each mode

208 ysymptomatic nature of motion sickness, high interindividual variability, and the extensive brain reg

209 We observed interindividual variability, most marked for cytokine tr

210 eat promise, its signal exhibits substantial interindividual variability, which needs to be accounted

211 smaller than the differences that are due to interindividual variability.

212 nt a complex ecosystem with a high degree of interindividual variability.

213 9 mm, and histologic composition showed high interindividual variability.

214 ypical sensory processing, with considerable interindividual variability.

215 to verify the microarray results and assess interindividual variability.

216 obiotic exposure, natural senescence, and/or interindividual variability.

217 henotypical traits, thus integrating genetic interindividual variability.

218 ese two features were combined could explain interindividual variability.

219 e in an individual, there is a high level of interindividual variability.

220 rait locus (QTL), accounting for half of the interindividual variability.

221 y exist between these pathologies and normal interindividual variability.

222 lower maximum decrease of TXB2, with marked interindividual variability.

223 (GluA2:GluN1; GluN2A:GluN2B), and determined interindividual variability.

224 ied young childhood as a stage of heightened interindividual variability.

225 s yields unsatisfactory results due to great interindividual variability.

226 thy donors, with minimal intraindividual and interindividual variability.

227 ogether, these findings explained 55% of the interindividual variance in WM capacity when combined wi

228 ion factor, kinase, or phosphatase with high interindividual variance of the expression level in adja

229 Interindividual variances of H3K4me3, H3K9ac, and H3K9me

230 Interindividual variant Creutzfeldt-Jakob disease (vCJD)

231 ithin individuals but exhibited considerable interindividual variation and was influenced by T1D-asso

232 PK showed little interindividual variation and were neither dose nor time

233 ion of miRNAs to human evolution, especially interindividual variation associated with miRNAs, is onl

234 ded to better define the dose effect and its interindividual variation for carotenoids and fat-solubl

235 There is interindividual variation in arsenic metabolism efficien

236 tween 1.7% (Ang-2) and 11.2% (sTie-2) of the interindividual variation in biomarker levels.

237 Lp(a) levels were higher with wider interindividual variation in blacks (median [interquarti

238 bolic end points, very little is known about interindividual variation in circadian-regulated metabol

239 Interindividual variation in cytosine modifications coul

240 0 GL-contributing food groups explained less interindividual variation in dietary GI (R(2): 0.376 com

241 We demonstrate systemic and stochastic interindividual variation in DNA methylation at the VTRN

242 hat average results may conceal considerable interindividual variation in drug response, leading to a

243 al role of noncoding RNAs as determinants of interindividual variation in drug response.

244 These results show that interindividual variation in glycated hemoglobin levels

245 Genetic variation contributes to the interindividual variation in growth factor levels and ex

246 methods confound the ability to investigate interindividual variation in gut microbiome profiles.

247 Interindividual variation in inosine monophosphate dehyd

248 Interindividual variation in mean leukocyte telomere len

249 ubstance in the world and presents with wide interindividual variation in metabolism.

250 ty to understand the genetics underlying the interindividual variation in metformin responses in orde

251 However, interindividual variation in methylation can also be a c

252 atocrit were strong phenotypic correlates of interindividual variation in multiple sterols and vitami

253 r results reveal common alleles that explain interindividual variation in pathogen sensing and provid

254 , LDLR and PCSK7), which in turn may promote interindividual variation in phenotypes.

255 There is considerable interindividual variation in platelet FcgammaRIIA activa

256 in vitro model of RSV infection to evaluate interindividual variation in response to RSV and identif

257 at single-neuron responses were sensitive to interindividual variation in scallop sequences, raising

258 cally highlighting the fornix as a source of interindividual variation in scene discrimination in hum

259 y aging population, but the genetic basis of interindividual variation in senescence remains largely

260 ifferences in RNA editing activity generates interindividual variation in silencing state within a po

261 There is substantial interindividual variation in smoking-related lung cancer

262 al strong heritable genetic contributions to interindividual variation in song tempo but that the deg

263 xplaining an additional 1.4% and 2.0% of the interindividual variation in systolic and diastolic BP,

264 factors contributing to the well-recognized interindividual variation in the progression and outcome

265 ndividualizing the current amplitude reduced interindividual variation in the stimulation focality by

266 investigated this heterogeneity by defining interindividual variation in the transcriptome of patien

267 Humans and animals exhibit substantial interindividual variation in this chemosensory reflex re

268 The DO mice display interindividual variation in toxicity response and, as s

269 85+ Study to investigate the extent of, and interindividual variation in, age-related changes in DNA

270 Interindividual variation is only partly accounted for b

271 Interindividual variation of band 3 and CD45 was low, 6

272 mparatively little is known about intra- and interindividual variation of condition in marine systems

273 Interindividual variation was much greater than that att

274 sed a similar increase in DOPAC/DA ratio but interindividual variation was significantly reduced.

275 CD protein concentration and calculation of interindividual variation which is difficult by other me

276 in chronic disease could be a consequence of interindividual variation, caused by factors such as xen

277 re more pronounced, but also exhibit greater interindividual variation, in IgG(+) and IgA(+) than in

278 Although there was some interindividual variation, in many patients suppression

279 ical response to desmopressin, showing large interindividual variation, may limit its clinical use.

280 We report a high level of interindividual variation, with low longitudinal variati

281 hypotheses about mechanisms contributing to interindividual variation.

282 ained in the pancreas of the HVs, with large interindividual variation.

283 achieved with statin therapy displayed large interindividual variation.

284 mine the contributions of the food groups to interindividual variations in dietary GI and GL.Overall,

285 Although a relatively rare phenomenon, interindividual variations in DM structure and compositi

286 ays an important role in accounting for such interindividual variations in drug response.

287 Data were also obtained on interindividual variations in flavanone bioavailability.

288 the dominant role that diet plays in shaping interindividual variations in host-associated microbial

289 and circuitry, of relevance to understanding interindividual variations in regulation of responses to

290 ng of the mechanism of action of analgesics, interindividual variations in responses to anesthetics a

291 We find that, even though interindividual variations in specific cell population f

292 The guppy is known to exhibit remarkable interindividual variations in spectral sensitivity of mi

293 pts at personalized medicine should consider interindividual variations in the active human gut micro

294 the A118G OPRM1 polymorphism contributes to interindividual variations in the function of neurotrans

295 Mammals exhibit marked interindividual variations in their gut microbiota, but

296 Interindividual variations in vaccine-induced immune res

297 irments with a personalised approach, taking interindividual variations into account, will further im

298 and successfully estimated and showed large interindividual variations of concentrations (2-3 orders

299 d in psychiatric disorders and predictive of interindividual variations of functional responses in he

300 We also found fewer interindividual variations using SUVmean as a quantitati