ライフサイエンスコーパス: interleukin-1 receptor-associated kinase

1 of the LPS signaling pathway at the level of interleukin-1 receptor-associated kinase.

2 of EGFR and the NF-kappaB regulatory kinase interleukin 1 receptor-associated kinase 1 (IRAK-1).

3 This included a Phe196Ser change in the interleukin 1 receptor-associated kinase 1 (IRAK1).

4 Interleukin 1 receptor-associated kinase 1(IRAK1), a key

5 We also demonstrate that MyD88, interleukin 1 receptor-associated kinase 1, and tumor ne

6 s study, we examined the contribution of the interleukin-1 receptor-associated kinase 1 (IRAK-1) to L

7 id differentiation primary response (MyD88), interleukin-1 receptor-associated kinase 1 (IRAK-1), and

8 ion with NF-kappaB-inducing kinase (NIK) and interleukin-1 receptor-associated kinase 1 (IRAK-1), deg

9 Here we report that interleukin-1 receptor-associated kinase 1 (IRAK1) is ov

10 Inhibition of BTK or interleukin-1 receptor-associated kinase 1 and 4 (IRAK-1

11 use of TMP with Bruton's tyrosine kinase or interleukin-1 receptor-associated kinase 1 and 4 inhibit

12 74 x 10(-6)) and a C203S polymorphism in the interleukin-1 receptor-associated kinase 1 gene (IRAK1)

13 rvival pathway, leading to downregulation of interleukin-1 receptor-associated kinase 1.

14 rvival pathway, leading to downregulation of interleukin-1 receptor-associated kinase 1.

15 main containing adaptor protein)-MyD88-IRAK (interleukin-1 receptor-associated kinase)1/4-TRAF6 (TNF

16 s undertaken to test the candidacy of IRAK1 (interleukin-1 receptor associated kinase-1) as an X chro

17 cts, we have identified a role for MyD88 and interleukin-1 receptor-associated kinase-1 (IRAK-1) in m

18 o-1 actions were likely to be independent of interleukin-1 receptor-associated kinase-1 (IRAK-1) regu

19 miRNA-146a down-regulates expression of the interleukin-1 receptor-associated kinase-1 (IRAK-1), an

20 h diminished IL-1beta-induced degradation of interleukin-1 receptor-associated kinase-1 (IRAK-1).

21 We report that B. vulgatus induced interleukin-1 receptor-associated kinase-1 degradation,

22 pression, myeloid differentiation factor 88, interleukin-1 receptor-associated kinase-1, and nuclear

23 ed NFkappaB activation, via interaction with interleukin-1 receptor-associated kinase 2 (IRAK2).

24 a series of pyrrolopyrimidine inhibitors of interleukin-1 receptor associated kinase 4 (IRAK4) using

25 B cells isolated from patients deficient for interleukin-1 receptor-associated kinase 4 (IRAK-4), mye

26 onse was reversed in the patient, but not in interleukin-1 receptor-associated kinase 4 (IRAK-4)-defi

27 Interleukin-1 receptor-associated kinase 4 (IRAK4) plays

28 ying very rare loss-of-function mutations in interleukin-1 receptor-associated kinase 4 (IRAK4), a cr

29 Interleukin-1 receptor-associated kinase 4 (IRAK4), a ma

30 diminished degradation and interaction with interleukin-1 receptor-associated kinase 4 (IRAK4).

31 he Toll-like receptor (TLR) pathway, such as interleukin-1 receptor-associated kinase 4 deficiency, h

32 Interleukin-1 receptor-associated kinase-4 (IRAK-4) is a

33 iation factor 88-dependent signaling through interleukin-1 receptor-associated kinase-4 and p38 leadi

34 l as GD1a itself inhibited flagellin-induced interleukin-1 receptor-associated kinase activation as w

35 nitude of flagellin signaling as measured by interleukin-1 receptor-associated kinase activation or t

36 ression induced by CpG DNA, and suggest that interleukin-1 receptor-associated kinase and/or TRAF6 ma

37 had impaired S aureus-induced activation of interleukin-1 receptor-associated kinase, c-Jun NH2 term

38 regulation of 2 inhibitors of TLR signaling: Interleukin 1 Receptor Associated Kinase (IRAK) M, and S

39 canonical downstream signaling intermediates interleukin 1 receptor-associated kinase (IRAK) and Ikap

40 demonstrate an NGF-dependent association of interleukin 1 receptor-associated kinase (IRAK) with the

41 n primary murine macrophages, dependent upon interleukin 1 receptor-associated kinase (IRAK-1).

42 In particular, a family of four interleukin 1 receptor-associated kinases (IRAK) regulat

43 tate level of toll-like receptor 5 (TLR5) or interleukin-1 receptor associated kinase (IRAK), but it

44 gh tyrosine nitration-mediated impairment of interleukin-1 receptor associated kinase (IRAK)4, a sign

45 Interleukin-1 receptor-associated kinase (IRAK) -1 plays

46 pathway involving the MyD88 adapter and the interleukin-1 receptor-associated kinase (IRAK) complex.

47 IRAK2, a member of the interleukin-1 receptor-associated kinase (IRAK) family,

48 nes encoding non-RD kinases belonging to the interleukin-1 receptor-associated kinase (IRAK) family.

49 L-1) stimulation leads to the recruitment of interleukin-1 receptor-associated kinase (IRAK) to the I

50 -1 stimulation, the majority of the cellular interleukin-1 receptor-associated kinase (IRAK) transloc

51 The interleukin-1 receptor-associated kinase (IRAK) was firs

52 Interleukin-1 receptor-associated kinase (IRAK), a signa

53 pretreatment in vivo inhibited expression of interleukin-1 receptor-associated kinase (IRAK)-1 while

54 , antisense JNK and dominant negative MyD88, interleukin-1 receptor-associated kinase (IRAK)-1, IRAK4

55 le, a Drosophila homolog of the human kinase interleukin-1 receptor-associated kinase (IRAK).

56 Here, we show that the interleukin-1 receptor-associated kinase (IRAK)/Pelle-li

57 receptor-4 (TLR4) and its signaling molecule interleukin-1 receptor-associated kinase (IRAK-1) play a

58 R4-mediated signaling pathway (reduced MyD88-interleukin-1 receptor-associated kinase [IRAK] interact

59 mammals and overlaps with the 5' UTR of the interleukin 1 receptor-associated kinase (IRAK1) gene.

60 Within innate immune signaling pathways, interleukin-1 receptor-associated kinases (IRAKs) fulfil

61 its DD and TIR domain and interacts with the interleukin-1 receptor-associated kinases (IRAKs) to for

62 mber 6, and rhophilin 2) and three proteins (interleukin 1 receptor-associated kinase-like 2, glutama

63 y factor-1, tumor necrosis factor-alpha, and interleukin-1 receptor-associated kinase-M mRNA in human

64 ly member, the mouse Pelle-like kinase/human interleukin-1 receptor-associated kinase (mPLK/IRAK), ha

65 Abs induced activation of TLR4 and triggered interleukin-1 receptor-associated kinase phosphorylation