ライフサイエンスコーパス: interleukin-1beta converting enzyme

1 atively termed ERICE (Evolutionarily Related Interleukin-1beta Converting Enzyme).

2 Mch3, a human enzyme that is related to the interleukin 1beta converting enzyme.

3 31-kDa interleukin 1beta precursor by human interleukin 1beta-converting enzyme.

4 trate for the proapoptotic cysteine protease interleukin 1beta-converting enzyme.

5 tor interacting protein (RIP)-RIP-associated interleukin-1beta converting enzyme and CED-3 homolog-1/

6 e ced-3, which encodes a protease similar to interleukin-1beta converting enzyme and related proteins

7 t caspases, showing the highest affinity for interleukin-1beta-converting enzyme and the second highe

8 Activated caspase-1 (interleukin-1beta converting enzyme) and caspase-3 (Yama

9 ed on the cysteine proteases, caspase-1 ICE (interleukin-1beta converting enzyme) and caspase-3 YAMA.

10 Actin cleaved by interleukin 1beta-converting enzyme can neither inhibit

11 Other caspases, namely interleukin-1beta-converting enzyme (caspase-1) and Ich-

12 or gene product Ced-3 is homologous to human interleukin-1beta-converting enzyme (caspase-1) has led

13 Yama belongs to the interleukin 1beta converting enzyme/ced-3 family of cyst

14 tudies have implicated the activation of the interleukin 1beta-converting enzyme/Ced-3 (ICE/Ced-3) fa

15 iation-specific patterns of expression of an interleukin-1beta converting enzyme/CED-3 (Caspase) fami

16 cation to occur and found that inhibition of interleukin-1beta converting enzyme/CED-3 family proteas

17 elling evidence that members of the caspase (interleukin-1beta converting enzyme/CED-3) family of cys

18 an Asp, suggesting involvement of a caspase (interleukin-1beta-converting enzyme/CED-3) family protea

19 Caspase-7 was the only detected interleukin 1beta converting enzyme family protease with

20 ot directly dependent upon activation of the interleukin 1beta-converting enzyme family of cell death

21 nstrate that peptide-based inhibitors of the interleukin 1beta-converting enzyme family of cysteine p

22 easured by viability, DNA fragmentation, and interleukin 1beta-converting enzyme family-mediated clea

23 a stoichiometric inhibitor of members of the interleukin-1beta converting enzyme family of cysteine p

24 Next, Bcl-2, interleukin-1beta converting enzyme family(CPP32-like) p

25 tion of the Bcl-2 family of proteins and the interleukin-1beta-converting enzyme family of proteases

26 s with differential sensitivity to Bcl-2 and interleukin-1beta-converting enzyme family protease inhi

27 In contrast, interleukin-1beta-converting enzyme family protease inhi

28 a cell extract known to contain CPP-32-like (interleukin-1beta-converting enzyme family) protease act

29 The ICE (Interleukin-1beta Converting Enzyme) family-recently nam

30 To determine whether the ICE [interleukin 1beta converting enzyme] family of proteases

31 tivation is dependent on caspase-8/FADD-like interleukin-1beta converting enzyme (FLICE)-mediated pro

32 and the initiating death protease FADD-like interleukin-1beta-converting enzyme (FLICE) (caspase-8).

33 and Fas-associated death domain (FADD)-like interleukin-1beta-converting enzyme (FLICE) inhibitory p

34 otein with death domain (FADD) and FADD-like interleukin-1beta-converting enzyme (FLICE), to induce a

35 te expression of the antiapoptotic FADD-like interleukin-1beta-converting enzyme (FLICE)-like inhibit

36 ontaining protein (FADD)/MORT1, or FADD-like interleukin-1beta-converting enzyme (FLICE)/caspase-8 in

37 t Fas-associated death domain protein (FADD) interleukin-1beta-converting enzyme (FLICE)/MACH was rec

38 The interleukin 1beta converting enzyme (ICE) family plays a

39 tion of several caspases including CPP32 and interleukin 1beta-converting enzyme (ICE or caspase 1),

40 apoptotic signal that requires activation of interleukin 1beta-converting enzyme (ICE) and CPP32beta,

41 We demonstrate that granzyme B processes interleukin 1beta-converting enzyme (ICE) and the ICE-re

42 Interleukin 1beta-converting enzyme (ICE) is a member of

43 Recently, we have demonstrated that interleukin 1beta-converting enzyme (ICE), a mammalian h

44 Inhibition of Fas killing by an interleukin 1beta-converting enzyme (ICE)-like protease

45 DLD1 colon carcinoma cells by up-regulating interleukin 1beta-converting enzyme (ICE)/caspase-1 and

46 ed by BaP, we studied the involvement of the interleukin 1beta-converting enzyme (ICE)/Ced-3 family o

47 ration- and time-dependent activation of the interleukin 1beta-converting enzyme (ICE)/CED-3-related

48 Inhibitors of interleukin-1beta converting enzyme (ICE) and a related

49 In contrast, members of the human interleukin-1beta converting enzyme (ICE) family of cyst

50 The Interleukin-1beta converting enzyme (ICE) family of prot

51 y differences in the biological roles of the interleukin-1beta converting enzyme (ICE) family proteas

52 the precursor and the mature polypeptides of interleukin-1beta converting enzyme (ICE) or a highly ho

53 ell death gene, ced-3, as a prototype of the interleukin-1beta converting enzyme (ICE) protease famil

54 port the preparation and characterization of interleukin-1beta converting enzyme (ICE) refolded from

55 similarities between Ced-3 and the mammalian interleukin-1beta converting enzyme (ICE) suggest that t

56 In contrast, no activation of caspase-1 (interleukin-1beta converting enzyme (ICE)) was observed.

57 infected persons by CH11 increased levels of interleukin-1beta converting enzyme (ICE), a protein ass

58 ned the role of two CRCP families-CPP32- and interleukin-1beta converting enzyme (ICE)-like cysteine

59 fector arm of which is composed of mammalian interleukin-1beta converting enzyme (ICE)-like cysteine

60 lso known as caspase 8 and FLICE, encodes an interleukin-1beta converting enzyme (ICE)-related cystei

61 ch-3 protein shares 54% identity with murine interleukin-1beta converting enzyme (ICE).

62 e proteases first defined by CED-3 and human interleukin-1beta converting enzyme (ICE).

63 es using selective peptide inhibitors of the interleukin-1beta converting enzyme (ICE)/caspase family

64 Although the interleukin-1beta converting enzyme (ICE)/CED-3 family o

65 eolytic processing of CPP32, a member of the interleukin-1beta converting enzyme (ICE)/CED-3 protease

66 We have sequenced the chicken interleukin-1beta-converting enzyme (ICE) and ced-3 homo

67 ct with CED-3 and its mammalian counterparts interleukin-1beta-converting enzyme (ICE) and FLICE.

68 d2/Ich-1), that encodes a protein similar to interleukin-1beta-converting enzyme (ICE) and the produc

69 In contrast to Fas expression, interleukin-1beta-converting enzyme (ICE) expression inc

70 r delays apoptosis, whereas proteases of the interleukin-1beta-converting enzyme (ICE) family are req

71 ng receptors CD95 (Fas/APO-1) and TNFR 1 and interleukin-1beta-converting enzyme (Ice) family members

72 CPP32, a member of the interleukin-1beta-converting enzyme (ICE) family of cyst

73 d the role of lipopolysaccharide priming, of interleukin-1beta-converting enzyme (ICE) inhibition, of

74 UV-induced apoptosis was blocked by interleukin-1beta-converting enzyme (ICE) inhibitor z-VA

75 Interleukin-1beta-converting enzyme (ICE) is a novel cys

76 Active interleukin-1beta-converting enzyme (ICE) is composed of

77 Members of the CED-3/interleukin-1beta-converting enzyme (ICE) protease (casp

78 In contrast, the CED-3/interleukin-1beta-converting enzyme (ICE) protease inhib

79 s of transfectants expressed a high level of interleukin-1beta-converting enzyme (ICE) protein and un

80 e family member similar or equivalent to the interleukin-1beta-converting enzyme (ICE) was implicated

81 ced-3 encodes a protein similar to mammalian interleukin-1beta-converting enzyme (ICE), a cysteine pr

82 is occurred without a detectable increase in interleukin-1beta-converting enzyme (ICE)-like or cystei

83 ligation resulted in the cleavage of common interleukin-1beta-converting enzyme (ICE)-protease targe

84 of a family of cysteine proteases related to interleukin-1beta-converting enzyme (ICE)-related protea

85 that it shares with members of the emerging interleukin-1beta-converting enzyme (ICE)/CED-3 family o

86 Interleukin-1beta-converting enzyme (ICE)/Ced-3 protease

87 Interestingly, although caspase-1 [interleukin-1beta-converting enzyme (ICE)], caspase-2, c

88 Interleukin-1beta-converting enzyme (ICE, caspase-1) reg

89 wpox virus (CPV), is reported to inhibit the interleukin-1beta-converting enzyme (ICE, caspase-1).

90 precursor (proIL-1beta) at an Asp-X site by interleukin-1beta-converting enzyme (ICE, recently terme

91 r ability to inhibit caspases, including the interleukin-1beta-converting enzyme (ICE; caspase-1).

92 re resistant to cell death induced either by interleukin-1beta-converting enzyme (*ICE) and ICE homol

93 at both EGF and IFN-gamma induced caspase 1 (interleukin-1beta converting enzyme [ICE]) gene expressi

94 The caspase-1 (interleukin 1beta-converting enzyme; ICE) titrant 3-[2-(

95 Based on the ability of CrmA to inhibit the interleukin-1beta converting enzyme in vitro, it has bee

96 hat one member of this group, hILP, inhibits interleukin-1beta-converting enzyme-induced apoptosis vi

97 or cellular Fas-associated death domain-like interleukin 1beta-converting enzyme inhibitory protein (

98 P (cellular Fas-associated death domain-like interleukin 1beta-converting enzyme inhibitory protein)

99 and Fas-associated death domain protein-like interleukin-1beta-converting enzyme inhibitory protein (

100 with target Fas-associated death domain-like interleukin-1beta-converting enzyme inhibitory protein e

101 of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme inhibitory protein i

102 s-associated protein with death domain)-like interleukin-1beta-converting enzyme inhibitory protein,

103 lar Fas-associated death domain protein-like interleukin-1beta-converting enzyme inhibitory protein-l

104 s-associating protein with death domain-like interleukin-1beta-converting enzyme) inhibitory protein

105 FLICE (Fas-associated death domain-like interleukin 1beta-converting enzyme)-inhibitory protein

106 gous FLICE (Fas-associated death-domain-like interleukin 1beta-converting enzyme)-inhibitory protein.

107 SHV protein Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein (

108 pression of Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein (

109 (FasL), and Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein (

110 ry protein, Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein (

111 nd cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein (

112 nd cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein (

113 only observed labeled fragment catalyzed by interleukin 1beta-converting enzyme is fragment 28-116 f

114 the expression of cellular FLICE (FADD-like interleukin-1beta-converting enzyme)-like inhibitory pro

115 e that the mdm2 oncoprotein is cleaved by an interleukin 1beta-converting enzyme-like protease (caspa

116 (CrmA), a competitive inhibitor of caspases, interleukin 1beta-converting enzyme-like proteases, whic

117 of some members of the bcl-2 family and the interleukin-1beta-converting enzyme-like cysteine protea

118 ular Fas-associated death domain (FADD)-like interleukin-1beta-converting enzyme-like inhibitory prot

119 ning in an amplifying cascade, with upstream interleukin-1beta-converting enzyme-like proteases activ

120 depletion of GSH is dependent on activity of interleukin-1beta-converting enzyme-like proteases but i

121 d after infection, suggesting that caspases (interleukin-1beta-converting enzyme-like proteases) were

122 chloromethyl ketone, a peptide inhibitor of interleukin-1beta-converting enzyme-like proteases, wher

123 specialized proteolytic cascade catalyzed by interleukin-1beta-converting enzyme-like proteases.

124 led yeast via a process that did not require interleukin-1beta-converting enzyme-like proteases.

125 rected against specific apoptotic proteases (interleukin 1beta converting enzyme, Nedd-2, and Apopain

126 ILPIP moderately protects against interleukin-1beta converting enzyme- or Fas-induced apop

127 he specific inhibitor of cysteine proteases (interleukin 1beta-converting enzyme protease family) blo

128 thesis inhibitors as well as Ac-YVAD-cmk, an interleukin 1beta-converting enzyme protease inhibitor,

129 The interleukin 1beta converting enzyme-protease-activating

130 enzyme in vitro, it has been speculated that interleukin-1beta converting enzyme-related proteases (c

131 which triggers cleavage and secretion of the interleukin 1beta converting enzyme substrate, pro-inter

132 mRNAs for inhibitory factor kappaBalpha and interleukin-1beta converting enzyme were found and quant