ライフサイエンスコーパス: interleukin-7 receptor

1 ineage potential was largely associated with interleukin 7 receptor alpha (IL-7R(alpha)) expression a

2 Up-regulation of the B-cell line 2, interleukin 7 receptor alpha and interleuking 2 receptor

3 face expression and RNA levels of CD127, the interleukin 7 receptor alpha chain (IL-7Ralpha).

4 n of a polymorphism in the gene encoding the interleukin 7 receptor alpha chain (IL7R) as a significa

5 o1 deficiency resulted in a severe defect in interleukin 7 receptor alpha-chain (IL-7Ralpha) expressi

6 udy we show that increased expression of the interleukin 7 receptor alpha-chain (IL-7Ralpha) identifi

7 The interleukin 7 receptor alpha-chain (IL-7Ralpha) is essen

8 nnate lymphoid cells (ILCs) that express the interleukin 7 receptor alpha-chain (IL-7Ralpha).

9 only high levels of PD-1 but also decreased interleukin-7 receptor alpha (CD127), an exhausted pheno

10 factor receptor (G-CSFR); and were uniformly interleukin-7 receptor alpha (IL-7Ralpha(-)) AA4.1(Lo),

11 e memory cells without undergoing changes in interleukin-7 receptor alpha (IL-7Ralpha) expression, di

12 Interleukin-7 receptor alpha (IL-7Ralpha) is essential f

13 (Th) cell subsets, ILC subsets positive for interleukin-7 receptor alpha (IL-7Ralpha) produce distin

14 The interleukin-7 receptor alpha (IL-7Ralpha) signaling path

15 ular or to the transmembrane domain (TMD) in interleukin-7 receptor alpha (IL7R) or cytokine receptor

16 elayed T cell responses and decreased CD127 (interleukin-7 receptor alpha [IL-7Ralpha] chain) convers

17 onstrated to regulate the gene expression of interleukin-7 receptor alpha chain (IL-7Ralpha) and post

18 t critically regulates the expression of the interleukin-7 receptor alpha chain (IL-7Ralpha) in T cel

19 Interleukin-7 receptor alpha chain (IL-7Ralpha) is induc

20 increased MS risk is the soluble form of the interleukin-7 receptor alpha chain gene (sIL7R) produced

21 of CD45RB and upregulated expression of the interleukin-7 receptor alpha chain, indicating a transit

22 Furthermore, expression of the interleukin-7 receptor alpha chain, which has been propo

23 x10(-8)), as were a nonsynonymous SNP in the interleukin-7 receptor alpha gene (IL7RA) (P=2.94x10(-7)

24 , a c-Kit(hi) progenitor subset positive for interleukin 7 receptor-alpha (IL-7Ralpha) emerged that h

25 pro-B cell stage due to a failure to express interleukin 7 receptor-alpha.

26 vitamin D(3), including genetic variants in interleukin-7 receptor-alpha (IL7RA*C), interleukin-2 re

27 ated STAT5 and high expression levels of the interleukin-7 receptor-alpha and interleukin-15 receptor

28 Functional studies validated interleukin-7 receptor-alpha as a Foxo1 target gene esse

29 d- (CD62L-) CC chemokine receptor 7- (CCR7-) interleukin-7 receptor alphaLo (IL-7RalphaLo) phenotype.

30 cells had markedly reduced expression of the interleukin 7 receptor and exhibited shorter survival.

31 memory precursors (expressing high levels of interleukin-7 receptor and low levels of killer cell lec

32 cell expansion is driven by signals from the interleukin-7 receptor and the pre-B-cell receptor and i

33 w) cells express B cell leukemia/lymphoma 2, interleukin-7 receptor, and CD5.

34 Mice lacking interleukin-7 receptor are lymphopenic, due to a defect

35 ed fraction of CD8(+) T cells expressing the interleukin 7 receptor at the peak of the response.

36 have demonstrated that downregulation of the interleukin-7 receptor (CD127) distinguishes Treg cells

37 e show that neonatal thymi transplanted into interleukin 7 receptor-deficient hosts harbor population

38 Thus ligands of the interleukin-7 receptor deliver an extrinsic signal that

39 f PU.1 as a transcriptional regulator of the interleukin-7 receptor has established one mechanism by

40 haracterized by selective down-regulation of interleukin-7 receptor, heightened apoptosis, and poor a

41 We show that activating mutations in the interleukin-7 receptor identified in human pediatric ETP

42 set by the proper signaling function of the interleukin 7 receptor (IL-7R) and the pre-T-cell antige

43 The molecular crosstalk between the interleukin 7 receptor (IL-7R) and the precursor to the

44 he pre-B cell antigen receptor (pre-BCR) and interleukin 7 receptor (IL-7R) coordinate pre-B cell pop

45 t to express TCRs can be subdivided based on interleukin 7 receptor (IL-7R) expression.

46 Mice lacking the interleukin 7 receptor (IL-7R) generate alpha/beta T cel

47 (pre-BCR) and escape from signaling via the interleukin 7 receptor (IL-7R).

48 In interleukin 7 receptor (IL-7R)alpha-/- murine thymocytes

49 hed by progressively lower expression of the interleukin-7 receptor (IL-7R alpha) and by lower IL-7 r

50 One unexpected result was the high level of interleukin-7 receptor (IL-7R) gene expression in HS-27a

51 Interleukin-7 receptor (IL-7R) levels are tightly contro

52 group is enriched for genes involved in the interleukin-7 receptor (IL-7R) pathway and T cell recept

53 The interleukin-7 receptor (IL-7R), via its activation of th

54 Here, we show that c-Kit and interleukin-7 receptor (IL-7R)-mediated signals support

55 Expression of the interleukin-7 receptor (IL-7Ralpha) chain marks function

56 tes from mice lacking the alpha-chain of the interleukin-7 receptor (IL-7Ralpha).

57 There was downregulation of interleukin 7 receptor (IL7R) (P = .0001) and chemokine

58 The interleukin 7 receptor (IL7R), which contains a unique a

59 apid apoptosis, and failed to upregulate the interleukin-7 receptor, known to be important for T cell

60 , effector CD8(+) T cells differentiate into interleukin-7 receptor(lo) (IL-7R(lo)) short-lived effec

61 Accordingly, populations of CD62L(high) interleukin-7 receptor-positive progenitor central memor

62 ated polyfunctional T helper cells with high interleukin-7 receptor, rapid clonal expansion, and pote

63 ), a linchpin in the pre-B-cell receptor and interleukin 7 receptor signaling pathways critical to B-

64 Human soluble interleukin-7 receptor (sIL7R)alpha circulates in high m