ライフサイエンスコーパス: intermediary

1 can manifest without a lymph node metastatic intermediary.

2 ized binding to methylated chromatin without intermediary.

3 lated that this may occur through an unknown intermediary.

4 utes by quantitatively drawing off TCA cycle intermediaries.

5 e controlled indirectly, via transcriptional intermediaries.

6 ochemically damaging the DNA through radical intermediaries.

7 ents from autothrophs via fungal mycorrhizal intermediaries.

8 sensitive to concentration effects of these intermediaries.

9 stablish interactions with various signaling intermediaries.

10 cid-base equilibrium distributions of energy intermediaries.

11 e of its interactions with various signaling intermediaries.

12 recipient through long paths of hundreds of intermediaries.

13 of principal neuronal activity via astrocyte intermediaries.

14 n enabling the repair process by recognizing intermediary abasic sites cleaving the phosphodiester ba

15 ream acetyl coenzyme A formation module; the intermediary acetyl-CoA activation module; and the downs

16 ibiting phosphorylation of the intracellular intermediaries AKT and extracellular signal-regulated ki

17 owth by introducing the CTC population as an intermediary and assuming dependency.

18 Genes involved in intermediary and secondary metabolism in fungi are frequ

19 ion, environmental perturbations, regulatory intermediaries, and molecular sequelae that ultimately l

20 therapies targeting 6 PAH-specific molecular intermediaries are used clinically.

21 t complexes (COA complexes) to form the Cox1 intermediary assembly module.

22 h Domain Criteria position these deficits as intermediaries between molecular and cellular mechanisms

23 that emphasize the role of astrocytes as key intermediaries between peripheral immune events, neurona

24 kinase activation, suggesting that Lbc is an intermediary between 5-HT and RhoA/ROCK, but not ERK.

25 we propose that Lpd is the hitherto unknown intermediary between Abl and Ena/VASP proteins.

26 ex has the requisite dynamics to serve as an intermediary between brain regions generating different

27 d phosphatase receptor (PTPRF) as a putative intermediary between extracellular glycosylated CSPGs an

28 the coding genome and provides an efficient intermediary between functional genomics data and revers

29 ism-not brain structure-that is the critical intermediary between genetics and the childhood risk to

30 organizing, self-replicating, auto-catalytic intermediary between macromolecules and cellular life.

31 Importantly, the phenotype of 3d mice was intermediary between MyD88(-/-) (highly susceptible) and

32 ogenesis and suggest that macrophages are an intermediary between neovascularization and organ archit

33 o the membrane, invokes the translocon as an intermediary between the fully hydrated and the fully in

34 Viral structural proteins form the critical intermediary between viral infection cycles within and b

35 osynthetic fuel-producing organism(s) or via intermediary biomass polymers that were previously deriv

36 nism-outcome propositions that postulate how intermediaries can contribute to promoting best practice

37 at certain individuals, collectively termed 'intermediaries', can contribute to implementation proces

38 This transformation probably involves an intermediary carbocation, based on observations with add

39 large variety of functions, such as being an intermediary carrier of the genetic information, transla

40 showed that IL-4-responsive monocytes are an intermediary cell, responding to IL-4 by elevating their

41 Rac1-GTPases serve as intermediary cellular switches, which conduct transient

42 derived the flow of resources from source to intermediary channel to recipient.

43 urine neutrophils led to a strongly impaired intermediary chemotaxis after CXCR2 activation which is

44 els play a pronounced role in CXCR2-mediated intermediary chemotaxis, whereas N-formyl-methionine-leu

45 ific role of TRPC6 channels in CXCR2-induced intermediary chemotaxis.

46 ral and hydrodynamic information revealed an intermediary compactness of the protein between globular

47 These data reveal p115 to be a critical intermediary component in the regulated secretion of MIF

48 s of PaaF and PaaG are adapted to accept the intermediary components of the Paa pathway, different fr

49 hese tumors formed without a benign polypoid intermediary, consistent with the lack of aberrant WNT s

50 Finally, the same intermediaries control the signaling response in tissues

51 and implements a desired limb trajectory, an intermediary control process between the behavioral goal

52 ness centrality measurements to identify key intermediary countries.

53 In contrast to its role at organ boundaries, intermediary CUP activity leads to growth promotion rath

54 ut and its mirror image were aligned with an intermediary cut-through polyester film and then thermal

55 Under limiting IsdC conditions, the IsdC intermediary cycles between heme-free and heme-containin

56 diffusion, use RNA cleavage to recover from intermediary depths, and are unable to recover from exte

57 but preceding swimming, making it a discrete intermediary developmental behavior.

58 For 2a (R = TMS), a 1,3-silyl shift gave an intermediary disilene, which was trapped as unique NHC-d

59 wall of cochlear outer hair cells and had an intermediary distribution (both cytoplasmic and cortical

60 d heterogeneous nuclear ribonucleoprotein as intermediary effectors in this feedback loop was interro

61 tosis, and microglial activation, as well as intermediary effects on cytokine upregulation.

62 studies, including bone turnover markers as intermediary endpoints.

63 tients based on baseline characteristics and intermediary events.

64 the dynamic nature of AAC as fast, slow, and intermediary exchanges between apoenzyme- and coenzyme-b

65 erum antibodies to oral bacteria might be an intermediary explanatory variable linking the associatio

66 Intermediary expression of CUP homologs is also observed

67 the absence of Foxo1, insulin signals via an intermediary extrahepatic tissue to regulate liver gluco

68 e sumoylation process by using transcription intermediary factor (TIF)-1gamma as a substrate.

69 E3 ubiquitin-protein ligase transcriptional intermediary factor 1 gamma (TIF1gamma) from binding SMA

70 s have been developed for anti-transcription intermediary factor 1 gamma, anti-MDA5 and anti-nuclear

71 c TH cells and identified that transcription intermediary factor 1 regulator-alpha (Tif1alpha)/tripar

72 , 2.01-119.90), whereas anti-transcriptional intermediary factor 1-gamma antibodies were protective (

73 d negatively associated with transcriptional intermediary factor 1-gamma antibodies.

74 that 4-mo-old mice deleted for transcription intermediary factor 1gamma (Tif1gamma) in HSCs developed

75 Transcriptional intermediary factor 1gamma (TIF1gamma; alias, TRIM33/RFG

76 e transcriptional regulator, transcriptional intermediary factor 1gamma, TIF1gamma, as an APC/C-inter

77 t, but instead statistically depended on the intermediary factor of diminished NREM SWA.

78 ed an essential role for the transcriptional intermediary factor TIF1gamma in erythropoiesis by regul

79 ng 28 (TRIM28; also known as transcriptional intermediary factor1beta and Kruppel-associated box-asso

80 Manipulation of the M factor and possible intermediary factors may result in female-to-male conver

81 anthropometric measurements, adjustment for intermediary factors, and exclusion of early deaths or p

82 CHMP4 when ESCRT-II and CHMP6 are present as intermediary factors.

83 These arise from intermediary fluorescent chlorophyll catabolites (FCCs)

84 Deeper understanding of the anatomical intermediaries for disease and other complex genetic tra

85 frequency, they could also serve as a unique intermediary for transferring quantum information betwee

86 ining primordial precursor, a "missing link" intermediary form of the ribonucleotide reductase family

87 ependent (per)oxidase reaction involving the intermediary formation of stable cysteine sulfenates.

88 The folding properties of intermediary forms in this deconstruction agree precisel

89 ntified where 4MI acts as a proton transport intermediary from the active site to ionizable residues

90 the transporter legacy of prestin, and this intermediary gateway, which shuttles anion-bound molecul

91 These orbital interactions involve the SOMO (intermediary generated from the stannyl radical addition

92 demographic characteristics, depression) and intermediary (health behaviors, health conditions) varia

93 ction of participants and increases in these intermediary hormones.

94 swine, and swine have been postulated as an intermediary host for the emergence of pandemic strains.

95 ase coupled cleavage (TREC) with yeast as an intermediary host for the genome editing.

96 dence suggests that dromedary camels are the intermediary host for the Middle East respiratory syndro

97 switching (mu-->gamma-->epsilon) in which an intermediary IgG phase is necessary for the affinity mat

98 These findings implicate miRs as intermediaries in aldosterone signaling in principal cel

99 Findings offer a new lens on the role of intermediaries in bridging the evidence to practice gap.

100 A20 captures polyubiquitinated signaling intermediaries in insoluble aggresomes, thus reducing th

101 im of this study was to evaluate the role of intermediaries in promoting infection prevention, and pr

102 geted mainly onto tufted cells, which act as intermediaries in the excitation between olfactory senso

103 We propose instead that EpsW is an intermediary in a multistep phosphorelay that regulates

104 either a common source of infection or as an intermediary in a transmission chain for hosts infected

105 of renal proximal tubule IL-11 is a critical intermediary in A1 adenosine receptor-mediated renal pro

106 sphatase receptor CD148 is shown to be a key intermediary in cell adhesion to S2ED, with downstream b

107 aB and stress kinase pathways and thus a key intermediary in cellular survival.

108 ane progestin receptor alpha (mPRalpha), the intermediary in DHP induction of OM.

109 rapies aimed at targeting its function as an intermediary in EGFR, MAPK and mTOR activation.

110 ansformed HMECs, implicating FAM83B as a key intermediary in EGFR/RAS/MAPK signaling.

111 Pyruvate is a key intermediary in energy metabolism and can exert antioxid

112 owth factor independent-1 (Gfi1), as a novel intermediary in glucocorticoid-induced IL-7Ralpha up-reg

113 zation of amorphous calcium carbonate, a key intermediary in synthetic, biological and environmental

114 d prostaglandin E2 has been implicated as an intermediary in the effects of UV radiation on BM cells.

115 the T4P assembly ATPase PilB functions as an intermediary in the EPS regulatory pathway composed of t

116 We further show that MAP3K2 is an intermediary in the signaling pathways that initiate lyt

117 Moreover, p53 is an intermediary in this regulation, as p38delta expression

118 cular inflammation is regulated by signaling intermediaries, including p38 mitogen-activated protein

119 s conformational change through a network of intermediary interactions.

120 ents include excessive channeling of glucose intermediaries into various metabolic pathways with gene

121 , mirroring the DeltaqseC strain, and has an intermediary intramacrophage replication defect in compa

122 indirect relationship with an algal biomass intermediary is plausible under some circumstances.

123 reas in high yields without the formation of intermediary isocyanates.

124 de is mediated by Hpo/Mst acting through the intermediary kinase Wts/Lats to phosphorylate the transc

125 d an ordered adhesive/antiadhesive composite intermediary layer between the medical tape backing and

126 Whether enhanced coupling through intermediary layers can also influence T(c) in the new h

127 (2) plane coupling through heavy metal oxide intermediary layers.

128 Particular styles and approaches used by intermediaries led to individual staff feeling personall

129 have a higher predominance in countries with intermediary levels of vaccine coverage.

130 a-induced pyridinoline (PYR) cross-links via intermediaries like LOX.

131 ole invasion (PTVI) pathway may represent an intermediary link between the endocytic and the penetrat

132 NA oligonucleotides using streptavidin as an intermediary linker.

133 n be established when paraphyly exists, (ii) intermediary links can be excluded when multiple lineage

134 o infer, and that the existence of unsampled intermediary links or common sources can never be exclud

135 ection of transmission and whether unsampled intermediary links or common sources existed make very d

136 tle is known about the metabolic fate of the intermediary long-chain (LC) n-3 polyunsaturated fatty a

137 te tea exposure assessment, and include both intermediary markers of risk as well as morbidity and mo

138 o many neurodegenerative conditions, but the intermediary mechanism is unclear.

139 ests that additional signalling molecules or intermediary mechanisms must be involved in the actual i

140 ively extrahepatic process, disrupts hepatic intermediary metabolic homeostasis after high fat mother

141 Moreover, the intermediary metabolic pathway of de novo lipogenesis, w

142 Nearly all changes in genes related to intermediary metabolic regulation were replicated in cul

143 rs have seen a resurgent interest in cardiac intermediary metabolism and a dramatic increase in our u

144 utaminase suggests a unique reprogramming of intermediary metabolism and a potential therapeutic stra

145 ydrogenase (Lpd), an enzyme central to Mtb's intermediary metabolism and antioxidant defense.

146 constituents, chemotaxis/motility machinery, intermediary metabolism and cellular physiology.

147 Numerous connections between products of intermediary metabolism and chromatin proteins have rece

148 Their crucial role in intermediary metabolism and energy conversion makes them

149 ansferases, thus representing a link between intermediary metabolism and epigenetic mechanisms of tra

150 monstrate that SIRT3 modulates mitochondrial intermediary metabolism and fatty-acid use during fastin

151 of the glycolytic pathway and other parts of intermediary metabolism and hence are called glycosomes.

152 ria play a central role in the regulation of intermediary metabolism and maintenance of normoglycemia

153 yl-CoA affects histone acetylation and links intermediary metabolism and transcriptional regulation.

154 er formalism describes key pathways of tumor intermediary metabolism and yields dynamic curves for po

155 formation about a whole range of pathways of intermediary metabolism can help to identify biomarkers

156 )H/(13)C metabolic flux analysis to quantify intermediary metabolism fluxes in both sedentary and tre

157 Histone acetylation depends on intermediary metabolism for supplying acetyl-CoA in the

158 Intermediary metabolism generates substrates for chromat

159 o mitochondria represents a critical step in intermediary metabolism impacting numerous diseases.

160 portunity to deepen our understanding of how intermediary metabolism impacts tumorigenesis.

161 These findings warrant future studies of intermediary metabolism in patients treated with beta-la

162 nd NADP(+) play a pivotal role in regulating intermediary metabolism in the heart.

163 NAD(+)/NADH and NADP(+)/NADPH in regulating intermediary metabolism in the heart.

164 molog 1 (LRH-1) is an important regulator of intermediary metabolism in the liver, but its role in re

165 w metabolic imaging technique that can probe intermediary metabolism nondestructively.

166 rturbations in amino acid, carbohydrate, and intermediary metabolism that were only transiently ameli

167 triking pattern of global underexpression of intermediary metabolism transcripts in BPH.

168 wall structure/function, cell division, and intermediary metabolism were also evident.

169 ternate substrates for energy generation and intermediary metabolism, and remodeling of the cell enve

170 recent studies and the relationships between intermediary metabolism, antibody production, and lifesp

171 in response, has long been known to regulate intermediary metabolism, but the details are poorly work

172 the obvious read out of hypoxia, effects on intermediary metabolism, has not been investigated.

173 and post-translational network that affects intermediary metabolism, ribosomal biogenesis, and prote

174 MV) infection causes dramatic alterations of intermediary metabolism, similar to those found in tumor

175 purines and pyrimidine biosynthesis, central intermediary metabolism, transport and binding.

176 lified by adaptive changes in the enzymes of intermediary metabolism.

177 or encephalopathies associated with impaired intermediary metabolism.

178 cancers with mutations of genes involved in intermediary metabolism.

179 otype provides productive insight into human intermediary metabolism.

180 cial steering function for the regulation of intermediary metabolism.

181 f ATP, and are involved in many reactions of intermediary metabolism.

182 essential cofactors for enzymes required in intermediary metabolism.

183 refore assessed the role of LRH-1 in hepatic intermediary metabolism.

184 circadian clock in the regulation of hepatic intermediary metabolism.

185 ylation regulates mitochondrial function and intermediary metabolism.

186 e cell's regulatory systems and its state of intermediary metabolism.

187 key link between inflammatory processes and intermediary metabolism.

188 ed from metabolites that are at key nodes of intermediary metabolism.

189 triggered by sulfhydration of key enzymes in intermediary metabolism.

190 enzymes that participate in key pathways in intermediary metabolism: carbamoylphosphate synthetase 1

191 ar Cell, Weinert et al. demonstrate that the intermediary metabolite acetyl-phosphate is an important

192 ly in the thalamus, but did not increase the intermediary metabolite, 7,8-BH(2).

193 he important role played by cross-feeding of intermediary metabolites (in particular lactate, succina

194 r machinery that controls the homeostasis of intermediary metabolites in mitochondria.

195 alizes the levels of a wide array of hepatic intermediary metabolites in multiple chemical classes, i

196 ss spectrometry-based platform to profile 63 intermediary metabolites in serial paired peripheral art

197 including glucose, amino acids, and various intermediary metabolites.

198 ope tracing of glycolytic and tricyclic acid intermediary metabolites.

199 drazine resulted in the formation of a black intermediary mixture that converted to a four-coordinate

200 d to guide the design and development of new intermediary models in healthcare, to promote best pract

201 nhibitor, we observed that ERK is a critical intermediary molecule for Ras-Raf-induced HO-1 expressio

202 Here, mRNA serves as a transient intermediary molecule in the information network, whilst

203 In addition, an intermediary monomer, bis(2-hydroxyethyl)terephthalate,

204 tion and thereby influences the formation of intermediary MR products as well as radicals.

205 neighbors from indirect junctions involving intermediary, multiply connected cells.

206 -cell responses both directly and through an intermediary nonlymphoid cell population.

207 te and dynamic time course data on signaling intermediaries, normally and in diabetes, we developed a

208 tart of the reaction (G-protein.GEF.GDP), an intermediary nucleotide-free binary complex (G-protein.G

209 lators and antioxidants, including important intermediaries of the tricarboxylic acid (TCA) cycle, am

210 otein association generally proceeds via the intermediary of a transient, lowly populated, encounter

211 ect of proline was mimicked by glutamate, an intermediary of proline metabolism.

212 Succinate, in addition to its role as an intermediary of the citric acid cycle, acts as an alarmi

213 less of the genotype (wild type, evolved, or intermediary) of the infecting virus.

214 The structure and properties of the intermediary oligomers have been difficult to study due

215 d discusses the impact of lead firms and key intermediaries on smallholders in different chain situat

216 en orthogonal DNA enantiomers via an achiral intermediary, opening the door for "heterochiral" DNA na

217 s of very similar frequency, but by using an intermediary optical mode, non-degenerate modes can inte

218 tivity or by inhibiting osteoclast signaling intermediaries or through negative feedback loops.

219 Using a metabolomics platform that analyzes intermediary organic acids, purines, pyrimidines, and ot

220 per A only via the reference list of a newer intermediary paper B, which has previously cited A.

221 phils in the healthy oral cavity occur in an intermediary parainflammatory state that allows them to

222 he viral-induced autophagic machinery via an intermediary partner, TUFM.

223 occur through the activation of alternative intermediary pathways.

224 y attenuated, while the double mutant has an intermediary phenotype.

225 tory responses and levels of the coagulation intermediary plasminogen activator inhibitor 1 in three

226 Here we provide an intermediary platform between HTS and mice by adapting m

227 ctural and electronic characteristics of the intermediary platinum arsenide layers.

228 Regulating intermediary polysulfide dissolution by understanding th

229 10 min) transformed jarosite to a green rust intermediary, prior to the subsequent precipitation of g

230 The intermediary processes in the assembly of MCC are not su

231 -nucleotide polymorphisms, affect particular intermediary processes such as gene expression.

232 e/paracrine C3ar1/C5ar1 signaling as crucial intermediary processes that link TLR stimulation to DC m

233 The concept of a long, intermediary, prodromal phase between the first appearan

234 and strongly basic conditions to convert the intermediary product 5,6-dihydrouridine-6-sulfonate (dhU

235 Analysis of intermediary products (neutralized, bleached and deodori

236 t understanding exactly what happens and how intermediaries promote best practice is unclear.

237 ugh an endochondral process with a cartilage intermediary prompting the hypothesis that hypoxic signa

238 00 and the p160 coactivator, transcriptional intermediary protein 2 (TIF2).

239 ctions of TSP2 may also include a role as an intermediary protein that facilitates transcellular rece

240 ng possible that Grb2 serves as a docking or intermediary protein.

241 ion on the channel protein or is mediated by intermediary proteins affecting the channel.

242 es, and can interact with membranes both via intermediary proteins and directly via its microtubule-b

243 e cilium to downstream effectors may require intermediary proteins that are largely unknown.

244 is that MreB accomplishes this feat through intermediary proteins that tether peptidoglycan synthase

245 To identify intermediary proteins, we isolated EBER2-PAX5-containing

246 ation, obviating any requirement for soluble intermediary proteins.

247 interactions and the metallic nature of its intermediary Pt(4)As(8) layer.

248 anin and madanin-1, without the need for any intermediary purification.

249 EGCG) inhibited formation of highly reactive intermediary radicals appearing during the Maillard reac

250 to be more efficient than EC as inhibitor of intermediary radicals during the MR.

251 ective differentiation from CD103(-)CD11b(+) intermediaries, rather than an isolated loss of CD103 ex

252 well as that whose translocation requires an intermediary receptor.

253 d and the low-energy azo pi* orbitals in the intermediary redox state and additional stabilization of

254 CUP is activated by dorsoventral genes in an intermediary region of the corolla.

255 ndirectly increases ltxA expression, but the intermediary regulator is unknown.

256 We propose that MgrA can serve as an intermediary regulator through which agr exerts its regu

257 A key intermediary regulator, the role of which had not previo

258 reviously unidentified structure type has an intermediary relationship between MB2 and MB12 type bori

259 embryo via the placenta, the maternal-fetal intermediary responsible for maintaining intrauterine ho

260 est that the endocannabinoid system plays an intermediary role in regulating rapid glucocorticoid eff

261 Bifurcated and intermediary salt-bridge and hydrogen-bond interactions

262 ism, but does not require nitric oxide as an intermediary signal.

263 d by a combined regulation of MET levels and intermediary signaling through mitogen-activated protein

264 The rings of intermediary size served as generalization stimuli, crea

265 The intermediary slow transition probably relates to the tra

266 protein expression of BMPR-II, the signaling intermediary Smad1, and the downstream genes, inhibitors

267 ype I and II BMP receptors and the signaling intermediaries (Smads), we demonstrated a key role for A

268 simple on-farm interventions like RBF can be intermediary solutions for communities in urbanizing wat

269 or of esophageal adenocarcinoma (EA) with an intermediary stage of dysplasia.

270 dence on whether these polymorphisms predict intermediary stage outcomes such as cognitive changes in

271 revious computational results implicating an intermediary state between formation of the first and se

272 ancers but of uncertain origin, served as an intermediary step in MV reversion to normal microvessels

273 Moreover, it can be used as an intermediary step in protein structure predictions eithe

274 They can be used as an intermediary step in protein structure predictions.

275 xes with high on and off rates, an important intermediary step in the HLA-I maturation process.

276 5D may be involved in modulating DMP-1 in an intermediary step.

277 Finally, minimal use of intermediary steps as well as direct, late stage C-7 hyd

278 a high-resolution imaging assay to visualize intermediary steps of the lateral to end-on conversion p

279 e from evolutionary processes, through which intermediary steps these arise, and whether they embody

280 ontent, were vacuum packing and freezing for intermediary storage times (24-32weeks) with a reported

281 sly characterized mutant, referred to as the intermediary strain, was isolated and characterized.

282 mologous DNA molecules that arise as central intermediary structures during homologous recombination

283 point confirmed these elements as the likely intermediary substrates that sponsored inversion formati

284 ional target prediction and found a putative intermediary TF, namely ETS1 in allergen-challenged CD4(

285 e strain (i.e. possible infectors) had fewer intermediaries than predicted by chance (P < 0.001), a f

286 vation induced cofilin dephosphorylation via intermediaries that include phosphatidylinositol 3-kinas

287 ates and activates Akt, an insulin signaling intermediary that regulates glucose and lipid metabolism

288 The lithosphere acts as the intermediary that transfers the effects of mantle dynami

289 o pathway cooperate to regulate, via rosette intermediaries, the intercalation of post-mitotic neuron

290 ble adjustment for confounders and potential intermediaries, the relative risk of SCD was significant

291 ike motif-containing domain functions as the intermediary through which the 14-3-3 protein modulates

292 zations were empowered to serve as financial intermediaries to pay the upfront recovery expenses for

293 loping new interventions/programmes that use intermediaries to plug the gap between theory and practi

294 ing our understanding about the potential of intermediaries to promote best practice.

295 e use of kernel functions that represent the intermediary transformation of the data into a different

296 ocess involves modification of the signaling intermediary tumor necrosis factor receptor-associated f

297 Findings showed that the ways in which intermediaries watch over practice (their human surveill

298 the FRET relay, the QD served as a critical intermediary where (1) an excited-state Tb donor transfe

299 erse activities must require tissue-specific intermediaries, which are largely unknown.

300 is high to replenish the TCA cycle with the intermediaries withdrawn for ectoines biosynthesis.