ライフサイエンスコーパス: intermediary metabolism

1 triggered by sulfhydration of key enzymes in intermediary metabolism.

2 nous compound with well-established roles in intermediary metabolism.

3 NOS may have important implications for the intermediary metabolism.

4 ganisms, carnitine has specific functions in intermediary metabolism.

5 endogenous activator that is a component of intermediary metabolism.

6 s for several cytosolic kinases important in intermediary metabolism.

7 lified by adaptive changes in the enzymes of intermediary metabolism.

8 or encephalopathies associated with impaired intermediary metabolism.

9 cancers with mutations of genes involved in intermediary metabolism.

10 otype provides productive insight into human intermediary metabolism.

11 cial steering function for the regulation of intermediary metabolism.

12 f ATP, and are involved in many reactions of intermediary metabolism.

13 essential cofactors for enzymes required in intermediary metabolism.

14 refore assessed the role of LRH-1 in hepatic intermediary metabolism.

15 circadian clock in the regulation of hepatic intermediary metabolism.

16 ylation regulates mitochondrial function and intermediary metabolism.

17 e cell's regulatory systems and its state of intermediary metabolism.

18 in iron metabolism, cell communication, and intermediary metabolism.

19 autophagy, is at least partially fulfilling intermediary metabolism.

20 obutyric acid (GABA) served as indicators of intermediary metabolism.

21 n-sensing and oxygen-dependent modulation of intermediary metabolism.

22 eses in liver, as well as for modeling liver intermediary metabolism.

23 f virtually all macromolecular synthesis and intermediary metabolism.

24 ute in parallel to an increasingly conserved intermediary metabolism.

25 grates environmental redox signals with core intermediary metabolism.

26 key link between inflammatory processes and intermediary metabolism.

27 phogluconolactonase, are also part of normal intermediary metabolism.

28 thioesters involved in different branches of intermediary metabolism.

29 tance to oxidative stress, iron storage, and intermediary metabolism.

30 ransmission and the short-term regulation of intermediary metabolism.

31 vitamin D handling in the skin or gut or its intermediary metabolism.

32 ed from metabolites that are at key nodes of intermediary metabolism.

33 Pyruvate plays a central role in intermediary metabolism.

34 dehydrogenase complexes that are central to intermediary metabolism.

35 , was postulated to extend life by affecting intermediary metabolism.

36 compartment that are involved in central and intermediary metabolism, a subset of which are required

37 regulates gene transcription associated with intermediary metabolism, adipocyte differentiation, and

38 rs have seen a resurgent interest in cardiac intermediary metabolism and a dramatic increase in our u

39 utaminase suggests a unique reprogramming of intermediary metabolism and a potential therapeutic stra

40 ydrogenase (Lpd), an enzyme central to Mtb's intermediary metabolism and antioxidant defense.

41 zing Cofactor for HNF1) acts as an enzyme in intermediary metabolism and as a binding partner of the

42 constituents, chemotaxis/motility machinery, intermediary metabolism and cellular physiology.

43 Numerous connections between products of intermediary metabolism and chromatin proteins have rece

44 r the hepatocytes express markers of hepatic intermediary metabolism and detoxification, we investiga

45 clones (61/115) encoded proteins involved in intermediary metabolism and electron transport, suggesti

46 geo/+) mice, suggesting preserved control of intermediary metabolism and energy balance.

47 Their crucial role in intermediary metabolism and energy conversion makes them

48 ansferases, thus representing a link between intermediary metabolism and epigenetic mechanisms of tra

49 monstrate that SIRT3 modulates mitochondrial intermediary metabolism and fatty-acid use during fastin

50 members of the family have defined roles in intermediary metabolism and generally perform these func

51 of the glycolytic pathway and other parts of intermediary metabolism and hence are called glycosomes.

52 ted by the insulin receptor, which regulates intermediary metabolism and its organization in cells.

53 ria play a central role in the regulation of intermediary metabolism and maintenance of normoglycemia

54 s the plasma membranes of organs involved in intermediary metabolism and storage.

55 a surprising number of proteins involved in intermediary metabolism and stress response were observe

56 Surprisingly, representative enzymes of intermediary metabolism and structural proteins do not a

57 o genetic networks, that of the E. coli core intermediary metabolism and that of the yeast protein-in

58 yl-CoA affects histone acetylation and links intermediary metabolism and transcriptional regulation.

59 K), I postulate that the association between intermediary metabolism and tumours varies over time.

60 er formalism describes key pathways of tumor intermediary metabolism and yields dynamic curves for po

61 al tRNA and rRNA genes, 3) genes involved in intermediary metabolism, and 4) an eclectic group of oth

62 Methylmalonyl-CoA mutase is a key enzyme in intermediary metabolism, and children deficient in enzym

63 hepatic functions, including bile formation, intermediary metabolism, and endobiotic/xenobiotic detox

64 ganization, excitation-contraction coupling, intermediary metabolism, and immune response.

65 xpression, transport of sugars and peptides, intermediary metabolism, and pH homeostasis.

66 ternate substrates for energy generation and intermediary metabolism, and remodeling of the cell enve

67 thways in the regulation of eating behavior, intermediary metabolism, and the onset of puberty.

68 available, the flexibility of the organism's intermediary metabolism, and the substrate specificity o

69 bon metabolism, cell wall synthesis, central intermediary metabolism, and transport.

70 recent studies and the relationships between intermediary metabolism, antibody production, and lifesp

71 lthough the metabolism and role of biotin in intermediary metabolism are well established, biotin rem

72 regulation of enzyme substrates involved in intermediary metabolism are well known.

73 major impact on the hepatic redox state and intermediary metabolism as a consequence of ethanol meta

74 thways of amino acid consumption and central intermediary metabolism as part of its transcriptome res

75 in response, has long been known to regulate intermediary metabolism, but the details are poorly work

76 thodology was used to follow the kinetics of intermediary metabolism by monitoring flux of 13C-labele

77 Additionally, they participate in intermediary metabolism, calcium signaling, and apoptosi

78 n basic cellular physiology, underlining how intermediary metabolism can affect the regulation of vir

79 formation about a whole range of pathways of intermediary metabolism can help to identify biomarkers

80 enzymes that participate in key pathways in intermediary metabolism: carbamoylphosphate synthetase 1

81 of secretory pathway components, enzymes of intermediary metabolism, cell-signaling components, and

82 g number of physiologic processes, including intermediary metabolism, cellular proliferation, and neu

83 contend that this Janus-faced relation with intermediary metabolism contributes to carcinogenesis; i

84 olved in specialized metabolism not found in intermediary metabolism databases, and thus can assist i

85 ides); genes that encode enzymes involved in intermediary metabolism, energy metabolism (tricarboxyli

86 oluble enzymes, amino acid biosynthesis, and intermediary metabolism evolve in a concentrated autocat

87 ctors, the cell envelope, energy metabolism, intermediary metabolism, fatty acid and phospholipid bio

88 )H/(13)C metabolic flux analysis to quantify intermediary metabolism fluxes in both sedentary and tre

89 Histone acetylation depends on intermediary metabolism for supplying acetyl-CoA in the

90 review new information on the regulation of intermediary metabolism gathered from the analysis of MI

91 Intermediary metabolism generates substrates for chromat

92 the obvious read out of hypoxia, effects on intermediary metabolism, has not been investigated.

93 o mitochondria represents a critical step in intermediary metabolism impacting numerous diseases.

94 portunity to deepen our understanding of how intermediary metabolism impacts tumorigenesis.

95 The core of intermediary metabolism in autotrophs is the citric acid

96 The study of intermediary metabolism in biomolecules has been given n

97 ystem, plays an important role in regulating intermediary metabolism in Escherichia coli ("catabolite

98 These findings warrant future studies of intermediary metabolism in patients treated with beta-la

99 pus) to further understand the regulation of intermediary metabolism in protein-rich versus oil-rich

100 idgut, and oenocytes: the principal sites of intermediary metabolism in the fly.

101 nd NADP(+) play a pivotal role in regulating intermediary metabolism in the heart.

102 NAD(+)/NADH and NADP(+)/NADPH in regulating intermediary metabolism in the heart.

103 molog 1 (LRH-1) is an important regulator of intermediary metabolism in the liver, but its role in re

104 convenient "chemical biopsy" for evaluating intermediary metabolism in the liver.

105 Analysis of genes encoding enzymes of intermediary metabolism indicated that low glucose broug

106 synthesis and of gluconeogenesis, such that intermediary metabolism is primarily catabolic; a crucia

107 erations of in vivo flux through pathways of intermediary metabolism leading to the differential prod

108 s identified are all enzymes, mostly serving intermediary metabolism, lipid metabolism, and/or antiox

109 We propose a model whereby defects in intermediary metabolism may be a causative factor of the

110 w metabolic imaging technique that can probe intermediary metabolism nondestructively.

111 ombines information about the genome and the intermediary metabolism of E.coli.

112 ombines information about the genome and the intermediary metabolism of E.coli.

113 ombines information about the genome and the intermediary metabolism of Escherichia coli.

114 glutamate, and thereby has a key role in the intermediary metabolism of glucose and amino acids.

115 raphy-mass spectrometry methodology to study intermediary metabolism of SUR1 knock-out (SUR1(-/-)) an

116 However, little is known about Mtb's intermediary metabolism or antioxidant defences.

117 st dynamic proteins appear to be enriched in intermediary metabolism proteins, cytoskeletal proteins,

118 the human system, including the pathways of intermediary metabolism, regulatory pathways, and signal

119 The data suggest that differences in intermediary metabolism render tumor cells susceptible t

120 and post-translational network that affects intermediary metabolism, ribosomal biogenesis, and prote

121 These results demonstrate how intermediary metabolism serves to connect biochemistry w

122 MV) infection causes dramatic alterations of intermediary metabolism, similar to those found in tumor

123 in complexes, as well as enzymes involved in intermediary metabolism, such as pyruvate dehydrogenase

124 coding capacity for biosynthesis and central intermediary metabolism than do free-living bacteria.

125 ts (e.g. p38MAPK and Rel A), and products of intermediary metabolism that are regulated by oxidative

126 f acute-phase proteins as well as changes in intermediary metabolism that provide substrate and energ

127 rturbations in amino acid, carbohydrate, and intermediary metabolism that were only transiently ameli

128 ATP-sensitive K+ channels (KATP) couple intermediary metabolism to cellular activity, and may pl

129 y intracellular ATP, allowing them to couple intermediary metabolism to cellular excitability, wherea

130 ination with a mass-balance model of hepatic intermediary metabolism to generate a comprehensive map

131 triking pattern of global underexpression of intermediary metabolism transcripts in BPH.

132 purines and pyrimidine biosynthesis, central intermediary metabolism, transport and binding.

133 nes normally associated with DNA metabolism, intermediary metabolism, transport, cellular redox, prot

134 in cofactor and small molecule biosyntheses, intermediary metabolism, transport, nitrogen fixation, r

135 A survey of selected pathways of central intermediary metabolism was also carried out, and genes

136 wall structure/function, cell division, and intermediary metabolism were also evident.

137 The fluxes through intermediary metabolism were then quantified by computer

138 adaptations are likely to involve Mtb's core intermediary metabolism, whose enzymes have been little