ライフサイエンスコーパス: intermediate filament protein

1 is the gene that encodes the major astrocyte intermediate filament protein.

2 ates expression of nestin, an embryonic cell intermediate filament protein.

3 ween the eye lens proteins and the ancestral intermediate filament protein.

4 treatments with serotonin, appeared to be an intermediate filament protein.

5 e intermediate filament protein vimentin, an intermediate filament protein.

6 y provide a novel nonmechanical function for intermediate filament proteins.

7 e up the type I (K9-K20) and type II (K1-K8) intermediate filament proteins.

8 nd keratin 18 (K18), two epithelial-specific intermediate filament proteins.

9 ined heptad repeat domains characteristic of intermediate filament proteins.

10 rminal domain, all common features of type 6 intermediate filament proteins.

11 keratins 8 (K8) and 18 (K18) as their major intermediate filament proteins.

12 otic cytoskeleton belonging to the family of intermediate filament proteins.

13 s and probably the most abundant of neuronal intermediate filament proteins.

14 keratins 8 (K8) and 18 (K18) as their major intermediate filament proteins.

15 all three tektin polypeptides is similar to intermediate filament proteins.

16 vement of the auxiliary beta subunit through intermediate filament proteins.

17 (K8/18) are simple epithelial cell-specific intermediate filament proteins.

18 ions at late times, containing predominantly intermediate filament proteins.

19 t function shared by K6, other keratins, and intermediate filament proteins.

20 nuclear organization, such as lamin nuclear intermediate filament proteins.

21 Other neuronal intermediate filament proteins (alpha-internexin, periph

22 Tax-binding protein as the neuronal specific intermediate filament protein, alpha-internexin.

23 patterns and function of internexin neuronal intermediate filament protein-alpha a (inaa), the encodi

24 nvestigate the roles of vimentin, a type III intermediate filament protein and a marker of epithelial

25 a previously unsuspected association between intermediate filament proteins and the adaptor complex A

26 ffer to those found both in the invertebrate intermediate filament proteins and the vertebrate lamins

27 Experiments with pan-specific antibodies to intermediate filament proteins and to cytokeratins sugge

28 ted the LNDR to LNDS in vimentin, a Type III intermediate filament protein, and have examined the imp

29 ures, (2) a comparison of their structure to intermediate filament proteins, and (3) their possible o

30 ined heptad repeat domains characteristic of intermediate filament proteins, and several of the mutat

31 ed its interactions with 14-3-3 and vimentin intermediate filament proteins, and vimentin depletion i

32 tive cancer cells, suggesting that these two intermediate filament proteins are necessary for fulvest

33 ich the type VI nestin and type III vimentin intermediate filament proteins are replaced by a series

34 defg) found in the alpha-helical sections of intermediate-filament proteins are hydrophobic, and the

35 Lamins, the type V nuclear intermediate filament proteins, are reported to function

36 eved to be a characteristic of the ancestral intermediate filament protein as it is found in many inv

37 protein as it is found in many invertebrate intermediate filament proteins but has been lost from al

38 mbiguous assignment to any existing class of intermediate filament protein, but exhibits a gene struc

39 unterparts of eukaryotic actin, tubulin, and intermediate filament proteins, but they also have cytos

40 Lengsin and lens intermediate filament proteins co-localize at the plasma

41 AP-3 and intermediate filament proteins cosedimented and coimmuno

42 Importantly, dL5 fusions to an intermediate filament protein CreS are significantly les

43 urvature in a manner similar to deleting the intermediate filament protein crescentin, but it does no

44 ntified a novel association of AIRE with the intermediate filament protein cytokeratin 17 (K17) in th

45 ile, TGF-beta1 induced the expression of the intermediate filament protein desmin and interstitial ma

46 Here we describe the muscle-specific intermediate filament protein desmin as a novel caspase

47 Mice lacking the intermediate filament protein desmin demonstrate abnorma

48 The intermediate filament protein desmin is encoded by the g

49 ticular, we show that S-nitrosylation of the intermediate filament protein desmin is significantly in

50 Mutations in the DES gene coding for the intermediate filament protein desmin may cause skeletal

51 easured being loss of immunostaining for the intermediate filament protein, desmin.

52 or as a chaperone for the reorganization of intermediate filament proteins during terminal different

53 The A-type lamins, nuclear intermediate filament proteins encoded by the LMNA gene,

54 oteins but has been lost from all vertebrate intermediate filament proteins except the nuclear lamins

55 nt sedimentation (VGS) indicate that soluble intermediate filament protein exists as an approximately

56 terphase cell, approximately 5% of the total intermediate filament protein exists in a soluble form.

57 been well characterized as an intracellular intermediate filament protein expressed broadly in mesen

58 ive cells was also positive for vimentin, an intermediate filament protein expressed by mesenchymal c

59 d by alteration of the repertoire of keratin intermediate filament proteins expressed within neoplast

60 Vimentin, a member of the intermediate filament protein family, is regulated both

61 The lens fiber cell-specific intermediate filament protein filensin is essential for

62 purified proteins revealed the lens-specific intermediate filament proteins filensin and CP49.

63 Mutations in intermediate filament protein genes are responsible for

64 ic inclusions in astrocytes that contain the intermediate filament protein GFAP in association with s

65 Although there was loss of expression of the intermediate filament proteins GFAP and vimentin, the ex

66 der resulting from missense mutations of the intermediate filament protein, GFAP.

67 aused by mutations in the astrocyte-specific intermediate filament protein glial fibrillary acidic pr

68 cells as determined by the expression of the intermediate filament proteins glial fibrillary acidic p

69 Insights into the role of the astrocyte intermediate filament protein, glial fibrillary acidic p

70 s in GFAP, which encodes the major astrocyte intermediate filament protein, glial fibrillary acidic p

71 The accumulation of the intermediate filament protein, glial fibrillary acidic p

72 ilated cardiomyopathy and indicate that this intermediate filament protein has an important role in c

73 Several hair-specific keratin intermediate filament proteins have been characterized,

74 Intermediate filament proteins have been reported to be

75 bules and microfilaments, but its effects on intermediate filament proteins (IFs) are unknown.

76 In addition, an increase in intermediate filament protein immunoreactivity (vimentin

77 Alpha-internexin, a neuronal intermediate filament protein implicated in neurodegener

78 Peripherin, a neuronal intermediate filament protein implicated in neurodegener

79 Simple-type epithelial keratins are intermediate filament proteins important for mechanical

80 nthesis may contribute to its function as an intermediate filament protein in radial glia.

81 Desmin is an intermediate filament protein in skeletal muscle that fo

82 understanding the role of Akt signaling and intermediate filament proteins in autophagy and cancer.

83 embly dynamics of neurofilament and vimentin intermediate filament proteins in cultured cells using c

84 lates the more than 20 keratin type I and II intermediate filament proteins in epithelial cells.

85 The changes in the expression levels of intermediate filament proteins in response to these trea

86 carboxyl-terminal ends of the rod domains of intermediate filament proteins in reverse transcriptase-

87 the E1B 19K protein is found associated with intermediate filament proteins in the cytoplasm and the

88 in 8 (K8) and keratin-18 (K18) are the major intermediate filament proteins in the intestinal epithel

89 Mutations in lamins A and C, nuclear intermediate-filament proteins in nearly all somatic cel

90 ns of the expression of vimentin, a type III intermediate filament protein, in alveolar epithelial ce

91 consisting of phosphorylated 14-3-3 binding intermediate filament proteins, including keratins, coup

92 from the brush border, and redistribution of intermediate filament proteins into the brush border.

93 Desmin, the muscle-specific intermediate filament protein is one of the earliest kno

94 at aberrant hyperphosphorylation of neuronal intermediate filament proteins is involved in AD.

95 The expression of intermediate filament proteins is remarkably tissue spec

96 Vimentin, an intermediate filament protein, is an M phase substrate f

97 6 (KRT16 in human, Krt16 in mouse), a type I intermediate filament protein, is constitutively express

98 peripherin gene, encoding a neuron-specific intermediate filament protein, is transcriptionally indu

99 Nestin, an intermediate filament protein, is widely used as stem ce

100 Expression of the intermediate filament protein keratin 17 (K17) is robust

101 The intermediate filament protein keratin 17 (Krt17) shows h

102 of the 14-3-3 protein family bind the human intermediate filament protein keratin 18 (K18) in vivo,

103 The intermediate filament protein keratin 8 (K8) and its cro

104 The intermediate filament protein keratin 8 (K8) is critical

105 between tTG and the breast-cancer marker and intermediate filament protein keratin-19.

106 Mutation of the cytoskeletal intermediate filament proteins keratin 8 and keratin 18

107 ility of the nucleus comes from meshworks of intermediate filament proteins known as lamins forming t

108 of the nuclear membrane is enriched with the intermediate filament protein lamin A.

109 We report that the intermediate filament protein lamin B, a component of th

110 The intermediate filament protein lamin B2 (LB2), normally a

111 in the LMNA gene, which encodes the nuclear intermediate filament proteins lamin A and C, two major

112 f glial fibrillary acidic protein (GFAP), an intermediate filament protein located within their cytop

113 c interaction of Tax and a neuronal specific intermediate filament protein may provide a clue to the

114 Cytokeratins, members of the family of intermediate filament proteins, may represent a new clas

115 transglutaminase-dependent reaction of this intermediate filament protein might influence the shape

116 4 residues in the otherwise highly conserved intermediate filament protein motif LNDR.

117 Among these is expression of the intermediate filament protein nestin and the brain fatty

118 We also have determined that the intermediate filament protein nestin correlates with tum

119 The intermediate filament protein Nestin identifies stem/pro

120 The intermediate filament protein Nestin labels populations

121 We found that the intermediate filament protein nestin physically interact

122 The intermediate filament protein Nestin serves as a biomark

123 These cells expressed the type VI intermediate filament protein nestin whose expression wa

124 IDE is known to bind the cytoplasmic intermediate filament protein nestin with high affinity.

125 to neurons and astrocytes, and expressed the intermediate filament protein nestin, a marker for proge

126 The intermediate filament protein, nestin, marks progenitor

127 Vimentin is an intermediate filament protein normally expressed in cell

128 ibrillary acidic protein (GFAP) is the major intermediate filament protein of astrocytes in the verte

129 pinal fluid that is specific for a cytosolic intermediate filament protein of astrocytes.

130 ere we examine the role of desmin, the major intermediate filament protein of muscle in organizing co

131 in keratin 8 (K8) and keratin 18 (K18), the intermediate filament proteins of hepatocytes, predispos

132 that 4.1R interacts with the characteristic intermediate filament proteins of postsynaptic densities

133 polypeptides 8 and 18 (K8/18) are the major intermediate filament proteins of simple-type epithelia.

134 How alterations in A-type lamins, intermediate filament proteins of the nuclear envelope e

135 Keratins 8 and 18 (K8/K18) are the intermediate filaments proteins of simple-type digestive

136 ysfunctional mutations in desmin, a type III intermediate filament protein, or alphaB-crystallin, a c

137 They also show that NF-M can partner with intermediate filament proteins other than the NF-H and N

138 Aberrant induction of expression of the intermediate filament protein peripherin, which is assoc

139 rker doublecortin and of the neuron-specific intermediate filament protein, peripherin, and by RA-sti

140 A- and alphaB-crystallins, the lens-specific intermediate filament proteins phakinin (CP49) and filen

141 All intermediate filament proteins possess three distinct do

142 Keratin 8 (K8) is a major intermediate filament protein present in enterocytes and

143 Vimentin, an abundant intermediate filament protein, presumably has an importa

144 Keratins are cytoplasmic intermediate filament proteins providing crucial structu

145 Here we show that keratin 17, an intermediate filament protein rapidly induced in wounded

146 clusion formation might extend to nonkeratin intermediate filament protein-related diseases.

147 We deleted the genes encoding two intermediate filament proteins required for astrocyte ac

148 st consistently is desmin, a muscle-specific intermediate-filament protein responsible for the struct

149 region of CP49 (BFSP2; phakinin), a related intermediate filament protein specific to the lens.

150 man medulloblastoma, including expression of intermediate filament proteins specific for neurons and

151 In addition, several intermediate filament proteins such as vimentin and anne

152 same or very similar sites in multiple other intermediate filament proteins, suggests that the proces

153 d that vimentin, a leucine zipper-containing intermediate filament protein, suppresses ATF4-dependent

154 The intermediate filament protein synemin is present in astr

155 Taken together, Nes-S is a new neuronal intermediate filament protein that exerts a cytoprotecti

156 BioID to lamin-A (LaA), a well-characterized intermediate filament protein that is a constituent of t

157 Keratin 17 (K17) is a type I intermediate filament protein that is constitutively exp

158 Keratin polypeptide 19 (K19) is a type I intermediate filament protein that is expressed in strat

159 GFAP is an intermediate filament protein that is expressed predomin

160 It is composed mainly of lamins, which are intermediate filament proteins that assemble into a fila

161 Lamins are intermediate filament proteins that assemble into a mesh

162 Lamins are intermediate filament proteins that form a scaffold, ter

163 A-type lamins are intermediate filament proteins that provide a scaffold f

164 ds hnRNP K, with that of peripherin, another intermediate filament protein, the RNA for which does no

165 he three major domains that characterize all intermediate filament proteins, the carboxyl-terminal ta

166 evelopment and function depend on the type V intermediate filament proteins, the lamins, which are ma

167 ast few years it has become evident that the intermediate filament proteins, the types A and B nuclea

168 ive slime of hagfishes contains thousands of intermediate filament protein threads that are manufactu

169 mutation in the gene for CP49 (phakinin), an intermediate filament protein thus far demonstrated only

170 P49 gene is the first vertebrate cytoplasmic intermediate filament protein to be described with an ex

171 Nestin is an intermediate filament protein, transiently and abundantl

172 mined the gene expression of two radial glia intermediate filament proteins, transitin and vimentin,

173 key cytoskeletal proteins, including several intermediate filament proteins, triggers the dramatic di

174 All three proteins have the basic intermediate filament protein tripartite structure, whic

175 anes, we identified by mass spectrometry the intermediate filament protein vimentin and the microtubu

176 ized GST-Raf-1 as bait, we have isolated the intermediate filament protein vimentin as a Raf-1-associ

177 was paralleled by the redistribution of the intermediate filament protein vimentin as well as by the

178 se to perform superresolution imaging of the intermediate filament protein vimentin by stimulated emi

179 The intermediate filament protein vimentin is involved in th

180 tor for activated C kinase 1 (RACK1) and the intermediate filament protein vimentin that correlated w

181 tion is accompanied by redistribution of the intermediate filament protein vimentin to form a cage su

182 All cells expressed the intermediate filament protein vimentin, an intermediate

183 dine salvage pathway, is associated with the intermediate filament protein vimentin, in NIH 3T3 fibro

184 The intermediate filament protein vimentin, which has been p

185 Focusing on the intermediate filament protein vimentin, which is frequen

186 both for desmin and the structurally related intermediate filament protein vimentin.

187 3-3 with a 55-kDa protein, identified as the intermediate filament protein vimentin.

188 elastic behavior of in vitro networks of the intermediate filament protein vimentin.

189 een the head domain and rod domain 1A of the intermediate filament protein vimentin.

190 llular histone proteins H2A, H3, and H4; the intermediate filament protein vimentin; the major HSV-1

191 onin significantly differed from that of the intermediate filament proteins vimentin and desmin as we

192 (ALYEQEIR, EAEEEKKVEGAGEEQAAAK) and another intermediate filament protein, vimentin (FADLSEAANR).

193 The intermediate filament protein, vimentin, was upregulated

194 d interaction between SspC and an eukaryotic intermediate filament protein was identified.

195 pping clones were identified that encoded an intermediate filament protein we subsequently named desm

196 nated alpha-tubulin associates strongly with intermediate filament proteins, we examined the contribu

197 or subdomains of murine vimentin, a Type III intermediate filament protein, were fused with either th

198 Vimentin is an intermediate filament protein whose 3'untranslated seque

199 Vimentin is an intermediate filament protein whose expression correlate

200 Keratin 9 (K9) is a type I intermediate filament protein whose expression is confin

201 Keratin polypeptide 20 (K20) is an intermediate filament protein with preferential expressi