ライフサイエンスコーパス: interneuronal

1 pike timing, potentially as a consequence of interneuronal abnormalities reflected by reduced parvalb

2 nism for hetero- and homosynaptic control of interneuronal activity and acetylcholine release in the

3 ed during seizures increases hippocampal CA3 interneuronal activity and suggests that a loss or impai

4 tamatergic and GABAergic inputs, synchronous interneuronal activity can produce a depolarizing synapt

5 ol of sympathetic preganglionic activity and interneuronal activity in the rat.

6 to the observed delay of firing, so that the interneuronal activity leads the burst cycle.

7 are thus important in initiating the intense interneuronal activity triggered by kainate, which in tu

8 Pyramidal and interneuronal activity was phase-locked not only to larg

9 ttributable to competition between segmental interneuronal and descending bulbospinal inputs, which r

10 d no direct synaptic connections between the interneuronal and motoneuronal elements that generate th

11 auditory epithelial cell synapses resembles interneuronal and nerve-muscle synapses, thereby definin

12 n is a bioactive neuropeptide that modulates interneuronal and neuromuscular synaptic transmission in

13 x depends on the preponderant involvement of interneuronal and principal cell networks, respectively.

14 ppocampus studied here, the profound loss of interneuronal and principal cell populations and consequ

15 pressed on a variety of cholinergic sensory, interneuronal, and motor neurons in myenteric ganglia.

16 s suggest that RGS4-dependent attenuation of interneuronal autoreceptor signaling is a major factor i

17 first documentation of gap junctions between interneuronal axon terminals in the mammalian forebrain.

18 Dephrin or DEph causes the abberant exit of interneuronal axons from the CNS, whereas ectopic expres

19 Both inhibitors caused interneuronal axons that normally would grow along the l

20 on and is also required for guidance of some interneuronal axons The involvement of Dock in the conve

21 gions of the GABAergic perisomatic-targeting interneuronal axons, including the parvalbumin-expressin

22 BLA via actions on both projection cells and interneuronal cell populations.

23 V1 INs differentiates as Renshaw cells, the interneuronal cell type that mediates recurrent inhibiti

24 lls biased to the production of cones and an interneuronal cell type, the horizontal cell (HC).

25 e mechanisms that generate these specialized interneuronal cell types from multipotential spinal prog

26 psychiatric disorders and encompass multiple interneuronal cell types.

27 n (1 sec) of a peripheral nerve activates an interneuronal central pattern generator that produces th

28 dal locomotion and may reflect activation of interneuronal central pattern-generating circuits.

29 The first might reflect interneuronal changes linked by gap junctions, whereas t

30 egulation of fast excitatory transmission at interneuronal cholinergic synapses in Drosophila.

31 Through live imaging of interneuronal cilia, we show that migrating interneurons

32 changes in the strength of a specific spinal interneuronal circuit: spinally mediated reciprocal Ia i

33 ss of SCN timekeeping is further enhanced by interneuronal, circuit-level coupling.

34 Deciphering the interneuronal circuitry is central to understanding brai

35 To determine the extent to which interneuronal circuitry studied with one approach can tr

36 Moreover, the ability to modulate local interneuronal circuits by tACS in a behaviorally relevan

37 ons to explore the possible ramifications of interneuronal circuits containing separate classes of GA

38 n of hip-mediated sensory feedback to spinal interneuronal circuits during dynamic conditions in peop

39 The expression of these spinal interneuronal circuits during imposed sinusoidal hip mov

40 serve coincidence detection, these cortical interneuronal circuits may be essential for salience sel

41 recordings, we found two previously unknown interneuronal circuits that link cortical layer 1-3 (L1-

42 ynchronization of oscillations in inhibitory interneuronal circuits, supporting the hypothesis that t

43 We propose that spinal GABAb-ergic interneuronal circuits, which are sensitive to baclofen,

44 cally depend on synaptic interactions within interneuronal circuits.

45 ts indicate that OPCs are a direct target of interneuronal collaterals and that the GABA-induced Cl(-

46 ethyl-D-aspartate receptors (NMDARs) mediate interneuronal communication and are broadly involved in

47 ation is critical for efficient and coherent interneuronal communication and, as revealed in animal s

48 channel and its associated impairment of SCN interneuronal communication lead to major deficits in th

49 y role for CaM-KII in shaping and regulating interneuronal communication, regardless of its modality.

50 tify V1- and V2b-derived neurons as the core interneuronal components of the limb central pattern gen

51 n Renshaw cell raises the possibility that R-interneuronal connections are formed precisely from the

52 ect evidence for a decrease in plasticity of interneuronal connections as animals make the transition

53 ctly on GnRH-1 neurons or indirectly through interneuronal connections.

54 for primary cilia-mediated GPCR signaling in interneuronal connectivity and inhibitory circuit format

55 ndrite elaboration influences the pattern of interneuronal connectivity and network function.

56 Interneuronal connectivity patterns and laminar distribu

57 Excitatory interneuronal connectivity within lamina II exhibited a

58 is associated with changes in the pattern of interneuronal connectivity within the segmental spinal c

59 disinhibition can be achieved despite dense interneuronal connectivity, even with random connections

60 e with a knockout of the neuronal (primarily interneuronal) connexin36.

61 oncomitant with an increase in the number of interneuronal contacts and cessation of neurite growth.

62 The results identify the pattern of interneuronal correlation in neural populations as a tar

63 by an ensemble of hundreds of neurons whose interneuronal correlation mimics that of the visual cort

64 Previously, we reported the strength of interneuronal correlation of spike count on the time sca

65 We analyzed the magnitude and interneuronal correlation of the variability in the acti

66 vity or variability of the response, nor the interneuronal correlation unexplained by the stimulus ("

67 We found that weak interneuronal correlation, or synchrony, allows the vari

68 visual fixation) influences the structure of interneuronal correlations and the accuracy of populatio

69 Interneuronal correlations and the representation of dif

70 model, choice probability and task-specific interneuronal correlations emerge from plasticity of top

71 We tested whether training changes interneuronal correlations in the dorsal medial superior

72 stimulus-specific changes in the pattern of interneuronal correlations that enhance the ability of n

73 correlated variability, and that using these interneuronal correlations yields oculomotor predictions

74 al and perceptual sensitivity, strengthening interneuronal correlations, and facilitating correlation

75 o supraoptic nucleus (SON) neurons increases interneuronal coupling in slices from lactating but from

76 Additionally, activation results in interneuronal coupling increases that are capable of bei

77 We show that interneuronal cytosolic coupling is severely reduced by

78 lyses and some genetic studies have reported interneuronal deficits and involvement of the DISC1, NRG

79 y using laser ablations or mutant lines with interneuronal deficits.

80 rites, the structural changes we observed in interneuronal dendritic arbors suggest that optic tectal

81 As interneuronal dendritic electrical coupling is almost ab

82 ent postsynaptic to asymmetrical contacts on interneuronal dendritic shafts.

83 g rate of a single MI cell; however, we find interneuronal dependencies in MI to be much more locked

84 , and/or (3) not incorporated the effects of interneuronal dependencies on firing rate.

85 A surprising feature of interneuronal development is the large extent of structu

86 Finally, we show that interneuronal DISC1 affects NRG1-ErbB4-mediated phenotyp

87 Neither a blockade of interneuronal discharge nor antagonists of several neuro

88 ed in several respects from previous data on interneuronal discharge patterns in anesthetized animals

89 ion was necessary for the synchronization of interneuronal discharge, which strongly supports a synap

90 enia in relation to neuronal orientation and interneuronal distance.

91 image analysis computer software we measured interneuronal distances and neuronal orientation.

92 There was no accompanying alteration of interneuronal distances, neuronal orientation.

93 ork coherence, indicating that plasticity of interneuronal diversity is likely to be an important mec

94 rneurons and neurogliaform cells, as well as interneuronal diversity itself, as important factors in

95 Interneuronal diversity reflects the division of labor b

96 tworks, and suggest a physiological role for interneuronal diversity.

97 on will likely be important in understanding interneuronal dysfunction following excitotoxic injury.

98 riety of conditions attributed to inhibitory interneuronal dysfunction, such as epilepsy, anxiety dis

99 In conclusion, the PRC possesses specific interneuronal equipment with unusually high proportion o

100 synaptic principal cells, and the control of interneuronal excitability is an important regulator of

101 During the late preictal phase, interneuronal excitability was high, but IPSCs, evoked b

102 These data demonstrate that interneuronal excitatory cholinergic synapses in Drosoph

103 nct anatomical and neurochemical features of interneuronal excitatory synapses.

104 fng is not required for the role of Notch in interneuronal fate choice, which we show is mediated by

105 ymmetric type: one is Engrailed positive (of interneuronal fate); and one is Engrailed negative (of e

106 These observations suggest that interneuronal firing elicits a GABAB-receptor-mediated e

107 However, what controls interneuronal firing remains incompletely understood.

108 tial of OPC GABA(A) currents was -43 mV, and interneuronal firing was correlated with transient depol

109 OS-evoked hyperpolarizations closely matched interneuronal firing, suggesting that HVc interneurons m

110 e over excitatory actions and thus moderates interneuronal firing.

111 As a test, the impact of dopamine on interneuronal GABA(A) receptor function was studied by c

112 gm model to evaluate the correlation between interneuronal GABAergic network activity and seizure-lik

113 fast onset pattern is mainly contributed by interneuronal (gamma-aminobutyric acidergic) signaling,

114 Interneuronal gap junctional coupling is a hallmark of n

115 After injury, interneuronal gap junctional coupling may mediate signal

116 nt of selective blockers of connexin36-based interneuronal gap junctions could be of therapeutic valu

117 This suggests that Cx36 interneuronal gap junctions selectively contribute to ga

118 Furthermore, the results indicate that interneuronal heterogeneity can change in neurological d

119 tial, indicating that lasting alterations in interneuronal heterogeneity can take place in real neuro

120 response profiles varied depending on their interneuronal horizontal distances.

121 In contrast, interneuronal inhibition was readily detected, comprisin

122 relatively weak--in contrast to feedforward interneuronal inhibition, which exerts strong effects on

123 s, in what way the spatiotemporal pattern of interneuronal input affects principal cell activity, and

124 ns in the peri-LC dendritic zone may provide interneuronal integration for LC noradrenergic neurons.

125 embrane protein-2 (VAMP-2) in neurons at the interneuronal junction of the central nervous system.

126 raffics from peripheral nerve endings to the interneuronal junction, there is limited understanding o

127 is is due to the fast activation kinetics of interneuronal K(+) currents.

128 Interneuronal kainate receptors (KARs) regulate GABAergi

129 organized hierarchically and contains three interneuronal levels, including two upper levels of "com

130 etinin (CalR) and GABA, markers that suggest interneuronal lineage.

131 s and overexpression of the early motor- and interneuronal marker islet.

132 labeled by using antibodies to a variety of interneuronal markers including parvalbumin (PV), vasoac

133 onally, Y1r-ir was also colocalized with the interneuronal markers studied.

134 period of corticogenesis and colocalize with interneuronal markers, suggesting that they play a role

135 inhibition of granule cells may provide the interneuronal mechanism for CFR-induced SS modulation.

136 ovide evidence for this by investigating the interneuronal mechanisms mediating behavioral choice bet

137 Our findings suggest that hippocampal interneuronal microcircuits are preferentially active du

138 reveals specific deficits in the patterns of interneuronal migration along the top of the developing

139 in interactions, modulate distinct routes of interneuronal migration and the consequent positioning o

140 of the Arx gene impairs GABA and cholinergic interneuronal migration but results in a neonatal lethal

141 hat the guidance cue receptors essential for interneuronal migration localize to interneuronal primar

142 n to cause Joubert syndrome induce defective interneuronal migration, suggesting that defects in cili

143 teracts with alpha3beta1 integrin to promote interneuronal migration.

144 Finally, an in silico interneuronal model incorporating the Kidins220-induced

145 iliary GTPase Arl13b in interneurons impairs interneuronal morphology and synaptic connectivity, lead

146 eizures in the entorhinal cortex starts with interneuronal network activity accompanied by a fast and

147 racellular potassium increases associated to interneuronal network activity consistently preceded the

148 We conclude that in the 4-AP seizure model, interneuronal network activity occurs before 4-AP-induce

149 th reduction of neuronal firing and enhanced interneuronal network activity.

150 In turn, the interneuronal network can presumably maintain subthresho

151 Inhibitory interneuronal network gamma (ING) oscillations may arise

152 Here we describe an interneuronal network in the marine mollusk Tritonia dio

153 rons may serve as an important mechanism for interneuronal network plasticity.

154 rhythmic activity, presumably arising in the interneuronal network, was blocked by the GABA(A) recept

155 her depends on the reconfiguration of shared interneuronal networks [1].

156 Interneuronal networks in neocortex underlie feedforward

157 s could constitute an important component of interneuronal networks in the ABL.

158 Our data demonstrate the involvement of interneuronal networks in the initiation of low-voltage

159 e bilateral, possibly related to commissural interneuronal networks involved in central pattern gener

160 nd developmental disorders, the diversity of interneuronal networks is compromised because of disturb

161 st time, we provide evidence that the spinal interneuronal networks linking the forelimbs and hindlim

162 work indicated that many pattern-generating interneuronal networks may have a modular organization a

163 ave predicted that the stable states of such interneuronal networks will be either synchrony (near ze

164 Simulated interneuronal networks with fast and slow synaptic kinet

165 lbar projection neurons by way of inhibitory interneuronal networks, allowing the projection neurons

166 parameters influence the firing patterns of interneuronal networks.

167 combinations of a small number of modules in interneuronal networks.

168 ion and re-engagement of rostrocaudal spinal interneuronal networks.

169 In particular, interneuronal neuropeptides appear to play roles in cogn

170 euronal density suggests that a reduction in interneuronal neuropil may constitute the anatomical sub

171 nal loss, neuronal metabolic dysfunction, or interneuronal neuropil reduction in the hippocampal regi

172 ed activity is complicated by the effects of interneuronal "noise" correlations between sensory neuro

173 ctural analysis revealed that in addition to interneuronal nuclei, ERalpha-I was affiliated with the

174 ulin-like growth factor-1 partially restored interneuronal number and reduced hypertrophy in some sub

175 is partially suppressed by the dentate gyrus interneuronal output in the intact brain.

176 caudal medulla serves as the final premotor interneuronal output system for vocalization.

177 This suggests that convergent interneuronal pathways exist which generate CMMCs.

178 En expression contributes to some aspect of interneuronal phenotype.

179 as Abeta1-40/42 and phospho-tau may increase interneuronal plaques and intraneuronal tangles, present

180 We report a mechanism of interneuronal plasticity that leads to the functional en

181 ental data demonstrate that modifications in interneuronal population variance influence the behaviou

182 e of cell to cell variability within defined interneuronal populations and the application of the Sha

183 ablish the pyramidal, granule, and GABAergic interneuronal populations as consisting of 7000, 400, an

184 A life-long turnover of sensory and interneuronal populations has been documented in the olf

185 ect some convergence of pathways on the same interneuronal populations involved in the regulation of

186 ituation where the axons of new afferent and interneuronal populations must insert into a highly spec

187 We identified spinal interneuronal populations targeted by the CST in the cer

188 These studies identified several interneuronal populations that may be involved in the hi

189 out the identity and contribution of defined interneuronal populations to mammalian locomotor behavio

190 ter construct differentiates between the two interneuronal populations.

191 ce of a particular parameter within specific interneuronal populations.

192 regulating the variance of key parameters in interneuronal populations.

193 s that distinguish excitatory and inhibitory interneuronal populations.

194 loping cortical plate, resulting in aberrant interneuronal positioning throughout the cerebral cortex

195 s in the olfactory bulb and continue to form interneuronal precursors into adulthood.

196 influences the differentiation of olfactory interneuronal precursors.

197 tial for interneuronal migration localize to interneuronal primary cilia, but their concentration and

198 laminar restriction of RGC dendrites and the interneuronal processes that synapse on them were not de

199 To test these hypotheses, we compared interneuronal progenitors in the medial ganglionic emine

200 ycine treatment did not affect the number of interneuronal progenitors.

201 (Even-skipped), and defects in serotonergic interneuronal projections.

202 The interneuronal propagation of aggregated tau is believed

203 e hypothesis that changes in the variance of interneuronal properties (e.g. in the degree of scatteri

204 ic afferent forms multiple contacts with the interneuronal proximal dendritic arbor, preferentially n

205 The stability of interneuronal pseudorabies virus labeling patterns follo

206 tation is commonly attributed to the loss of interneuronal regulation by inhibitory D(2) dopamine rec

207 s demonstrate that the plastic nature of the interneuronal resting membrane potential underlies a uni

208 lices suggests that synergy does not rely on interneuronal signaling and may occur within single subc

209 Hence, neuropeptidergic interneuronal signaling confers a canonical property upo

210 Finally, we show that interneuronal signaling is sufficiently powerful to main

211 Neurotransmitters are essential for interneuronal signalling, and the specification of appro

212 To characterize interneuronal signals responsible for robust pacemaking

213 capable of exerting cell-specific effects on interneuronal signals?

214 ostsynaptic inhibition of several downstream interneuronal sites in the startle circuit.

215 y underlying habituation occurs primarily at interneuronal sites.

216 itive firing evoked by the activation of the interneuronal somatic/dendritic KA receptors.

217 c tectum, which are distributed with a wider interneuronal spacing than in Neognathae.

218 erneuronal subtypes might change, and entire interneuronal species can be lost from the network.

219 of labor between numerous highly specialized interneuronal species, each performing a set of specific

220 ment of the number and relative abundance of interneuronal species.

221 ses the evoked IPSC indirectly by increasing interneuronal spiking and GABA release, leading to activ

222 ntaneous GABA release through an increase in interneuronal spiking.

223 etected in the brain on day 1 PI, with rapid interneuronal spread of infection leading to death by da

224 he flow of descending signals to the modular interneuronal structures of the spinal cord.

225 GAD67 downregulation occurs in multiple interneuronal sub-populations, including the parvalbumin

226 addition to the complete or partial loss of interneuronal subgroups, heterogeneity can also be alter

227 min-positive (PV+) interneurons are the main interneuronal subpopulation exhibiting alpha1 immunoreac

228 parvalbumin-positive INs (PV-INs), the major interneuronal subpopulation in BLA, in the disinhibitory

229 PV) was used as a marker for the predominant interneuronal subpopulation in this nucleus.

230 e is known about the synaptic outputs of the interneuronal subpopulation that expresses somatostatin

231 Although previous studies have shown that interneuronal subpopulations containing parvalbumin (PV)

232 and calbindin-D28K (CB) labeled two separate interneuronal subpopulations in the ABL.

233 dicate that there are at least four distinct interneuronal subpopulations in the ABL: (1) PV+ neurons

234 e is known about the connections of specific interneuronal subpopulations in this region.

235 pendent protein kinase II, whereas different interneuronal subpopulations were labeled by using antib

236 o regulating the excitability of the primary interneuronal subtype in the bulb, M1 receptors regulate

237 A similar interneuronal subtype was also found in GAD65-EGFP-negat

238 These newly identified interneuronal subtypes appeared to be closely related to

239 Immunocytochemical analysis for different interneuronal subtypes demonstrates that ectopia contain

240 auma and seizures, the relative abundance of interneuronal subtypes might change, and entire interneu

241 r properties of GABAergic input on different interneuronal subtypes might have important consequences

242 e mammalian cerebral cortex the diversity of interneuronal subtypes underlies a division of labour su

243 scillation-dependent discharges by two major interneuronal subtypes, the perisomatically projecting p

244 romiscuous gap junctions formed with various interneuronal subtypes, volume transmission, and the abi

245 tion, specification or migration of specific interneuronal subtypes.

246 To test roles for agrin in interneuronal synapse formation, we studied hippocampi f

247 it targets specific receptor subtypes to the interneuronal synapse in vivo.

248 sis coli protein (APC) as a key regulator of interneuronal synapse maturation.

249 etylcholine receptors (nAChRs) at developing interneuronal synapses and report the isolation of trans

250 The kinetics of cholinergic currents at interneuronal synapses are dictated by the peripheral ta

251 ce in the mechanisms that govern assembly of interneuronal synapses as compared to the neuromuscular

252 erlies the formation of the diverse types of interneuronal synapses but differs from that responsible

253 Moreover, interneuronal synapses exhibited higher rates of spontan

254 on was connected to another neuron, not only interneuronal synapses, but also the autaptic synapses o

255 At interneuronal synapses, neuregulin ErbB receptors associ

256 atterning of a presynaptic marker at certain interneuronal synapses.

257 acetylcholine receptor (nAChR) targeting to interneuronal synapses.

258 etal neuromuscular junctions and cholinergic interneuronal synapses.

259 amplitude, charge, and RRP size compared to interneuronal synapses.

260 Neuronal pairs formed both interneuronal synaptic and autaptic connections indiscri

261 hat both acetylcholine and GABA mediate fast interneuronal synaptic transmission in Drosophila.

262 rons may modulate gamma frequency by shaping interneuronal synchronization.

263 potentials may be a critical determinant of interneuronal synchronous bursting in the hippocampus.

264 ate connections of afferents to a functional interneuronal system are clearly present by the eighth i

265 e and physiological actions suggest that the interneuronal system of neuropeptides is crucial for mai

266 r neurons of the pharynx via a glutamatergic interneuronal system.

267 rain, relegating muscle activation to spinal interneuronal systems.

268 s, which may spread throughout the cortex by interneuronal tau transfer.

269 escence and electron microscopy suggest that interneuronal terminals are in direct contact with OPCs,

270 monstrations that the secretion, uptake, and interneuronal transfer of tau can be modulated by diseas

271 observed between cells of differing putative interneuronal type, arguing against gap junctions as the

272 rence to arbors of an abundant, well-defined interneuronal type.

273 GABAergic interneuronal types are silenced or fire during these ev

274 nd phase-preferential discharges of distinct interneuronal types spontaneously emerged from the isola

275 Interneuronal unitary IPSCs are several times larger bec

276 there were parameter ranges where increased interneuronal variance decreased the inhibition of princ