ライフサイエンスコーパス: interprotein

1 ndicated that a significant component of the interprotein affinity is contributed by FVIIIa subunits

2 buffered diffusion of intracellular Ca(2+), interprotein allosteric interactions also contribute to

3 Interprotein and enzyme-substrate couplings in interfaci

4 These data suggest that perturbing interprotein associations with urea in situ allowed the

5 l beta, whereas the entropy-driven aspect of interprotein binding appears to be contributed by the 31

6 ransglutaminases, which introduce intra- and interprotein chain cross-links.

7 as the terminal leucine zipper domains form interprotein coiled-coil cross-links, and (2) it express

8 n to be active, suggests the hypothesis that interprotein complementation by two individually nonfunc

9 mimic the spacing in the FGF4 enhancer, the interprotein contact surface is reduced, and the translo

10 A majority of the most probable interprotein contacts are also native contacts, suggesti

11 These results suggest that formation of interprotein contacts by NC is essential to the normal H

12 that changes in distance across hydrophobic interprotein contacts have similar effects on both elect

13 vely, the capacity of NC to bind RNA or make interprotein contacts might affect particle assembly.

14 replacement of NC by polypeptides which form interprotein contacts permitted efficient virus particle

15 We identified intra- and interprotein cross-links for all editosome subunits that

16 are located on the surface of subtilisin at interprotein crystal contacts.

17 (2) The interprotein distance at which the transition occurs sug

18 -protein interface causes an increase in the interprotein distance within the protein complex.

19 GR can catalyze isomerization of protein and interprotein disulfide bonds and localized this function

20 nteractions, and leads to formation of novel interprotein disulfide bonds.

21 ndently activated by oxidation that involves interprotein disulfide formation within this homodimeric

22 Cys-55) is paired with Cys-46 of Trx in the interprotein disulfide intermediate of the overall oxida

23 The Ialpha isoform, PKGIalpha, formed an interprotein disulfide linking its two subunits in cells

24 Fluorescence spectroscopy implicates interprotein dityrosine as one of the dimerization motif

25 tion between their static structures and the interprotein dynamics: i.e., the consequence of the exte

26 eV higher than the experimental estimate for interprotein electron self-exchange in cytochrome b5.

27 mains on CcP has been probed by photoinduced interprotein electron transfer (ET) between zinc-substit

28 Interprotein electron transfer (ET) occurs between the t

29 Interprotein electron transfer (ET) reactions play an im

30 ibe the first observations of photoinitiated interprotein electron transfer (ET) within sol-gels.

31 Theoretical study of interprotein electron transfer across an aqueous interfa

32 and the rate-limiting step appears to be the interprotein electron transfer from heme in QHNDH to the

33 Interprotein electron transfer is a likely rate-limiting

34 ytochrome c-551i form a complex within which interprotein electron transfer occurs.

35 cture of the complex allows us to propose an interprotein electron transfer pathway involving the hig

36 Interprotein electron transfer plays an important role i

37 Interprotein electron transfer underpins the essential p

38 nges that control component protein docking, interprotein electron transfer, and substrate reduction.

39 To investigate interprotein electron transfer, chemically reduced MMOR

40 and the structure and function of intra- and interprotein electron transfer, we have determined the c

41 n mediates the coupling of ATP hydrolysis to interprotein electron transfer, whereas the active site

42 ism to minimize the reorganization energy of interprotein electron transfer.

43 p is essential to the biological function of interprotein electron transfer.

44 rotein interaction and determine the rate of interprotein electron transfer.

45 apsulated metalloproteins, and establish the interprotein electron transfer.

46 a physiologic complex which is required for interprotein electron transfer.

47 reorganizational energy associated with this interprotein electron-transfer reaction is also discusse

48 2 complex: (i) Docking calculations based on interprotein electrostatic interactions identified possi

49 Interprotein ET from quinol MADH to the high-valent bis-

50 duced by a generalized kinetic model for the interprotein ET photocycle.

51 eas the R65A and R310A mutations lowered the interprotein ET rate by 20-30-fold without perturbing th

52 lobin (Mb) and cytochrome b(5) (b(5)) reveal interprotein ET rates comparable to those observed withi

53 To examine the precise role of Met51 in this interprotein ET reaction, Met51 was converted to Ala, Ly

54 is also related to mechanisms of other gated interprotein ET reactions.

55 n the kinetic mechanism of regulation of the interprotein ET with effects that are intermediate betwe

56 viscosity independence is indicative of true interprotein ET, rather than dynamic gating as seen in p

57 se states conformational fluctuations enable interprotein ET.

58 Interprotein fluorescence resonance energy transfer expe

59 This method depends solely on interprotein gradients in amino acid usage.

60 H2O2 induces a 50-kDa DJ-1 interprotein homodimer disulfide, known to form between

61 Asn M187, Asn M188, and Gln L258 which form interprotein hydrogen bonds to cyt in the cyt-RC complex

62 ons responsible for the dramatic increase in interprotein interaction and promoting the formation of

63 e and temperature dependence of the relevant interprotein interaction energies.

64 l changes influence protein size, shape, and interprotein interaction strength.

65 alpha-synuclein misfolded states by enhanced interprotein interaction.

66 rdered surface epitopes capable of mediating interprotein interactions and is not strongly influenced

67 Significant changes occur in the interprotein interactions as a result of differences in

68 left-handed beta helix are all critical for interprotein interactions between eIF2B subunits necessa

69 ernal side of the DNA loop and have numerous interprotein interactions that increase the stability an

70 re carried out, and detailed analysis of the interprotein interactions undertaken.

71 eic acid, HIV-1 Gag displays moderately weak interprotein interactions, existing in monomer-dimer equ

72 is explicable in terms of highly anisotropic interprotein interactions, which are averaged out in the

73 s features to the magnitude of the effective interprotein interactions.

74 g protein concentration because of favorable interprotein interactions.

75 e the ability to accurately model intra- and interprotein interactions.

76 Misfolding is accompanied by an increase in interprotein interactions; however, near the folding tem

77 s, navigating intraprotein intersections and interprotein interfaces efficiently, remains a mystery t

78 ds on strain energy distribution at specific interprotein interfaces.

79 We propose that LC form fibrils via an interprotein loop swap and that the underlying conformat

80 s also formed as the major product of direct interprotein metal exchange between Cd7MT and Ag12MT.

81 Interprotein metal exchange between Cu12-MT and Cd7MT le

82 ement reactions of Cd7MT with Ag+ or Cu+ and interprotein metal exchange reactions between Cd7MT and

83 to donate Ag+ to Zn7MT and Zn4Ag6MT via slow interprotein metal exchange reactions.

84 e reactions revealed the existence of a slow interprotein metal redistribution process that follows i

85 To better determine the role of MT in interprotein metal transfer, we describe a procedure tha

86 usivity, local protein segment dynamics, and interprotein packing as a function of aggregation time,

87 so use the scaling parameter of the obtained interprotein rate distribution to construct a rooted who

88 proteins encoded in 19 complete genomes (the interprotein rate distribution).

89 We demonstrate that the interprotein rate distributions inferred from the genome

90 Each interprotein reaction now occurs in two steps: a mobile

91 y to match interacting paralogs, to identify interprotein residue-residue contacts and to discriminat

92 r stabilization of the protein complex by an interprotein salt bridge between Arg99 of amicyanin and

93 terminus are observed, depicting an array of interprotein salt bridges between Trx and the strictly c

94 rom Natronobacterium pharaonis (phR) and the interprotein spectral shift between them.

95 tropic attraction strongly affects the local interprotein structure and leads to an anomalously large

96 Because of interprotein subunit clashes, only a few families of TA