ライフサイエンスコーパス: interrogation

1 putative lncRNAs for downstream experimental interrogation.

2 full extrusion of every encountered base for interrogation.

3 rge magnitude at any particular frequency of interrogation.

4 diagnostic training and to permit additional interrogation.

5 a resource of candidate PD genes for future interrogation.

6 a change in redox current upon voltammetric interrogation.

7 cated tumour vulnerabilities for therapeutic interrogation.

8 work and provide an interactive web-tool for interrogations.

9 effective tool that supports unique digital interrogation and analysis of kidney tissue from animal

10 ith NH3 are established through experimental interrogation and computational analysis of materials ac

11 ety of forms, offering new approaches to the interrogation and control of polarization-sensitive ligh

12 blockade and the compelling need for greater interrogation and data integration of both host and tumo

13 r/effector expression for functional circuit interrogation and in vivo genome editing in targeted neu

14 cates that the mechanisms of nonspecific DNA interrogation and protein oligomer formation elucidated

15 ifted the emphasis of research toward causal interrogations and increased the demand for more precise

16 utility of systematic routine CIED removal, interrogation, and analysis at autopsy.

17 esources will enable widespread utilisation, interrogation, and refinement of candidate naive cells.

18 has previously proven refractory to genetic interrogation, and the parasite exported kinase FIKK10.1

19 The candidate region interrogation approach identified two of the nine loci p

20 using both genome-wide and candidate region interrogation approaches and to evaluate gene-environmen

21 iated protein 9 (Cas9) guide RNAs and target interrogation are not well defined in living cells.

22 antable electronic device (CIED) removal and interrogation are recommended at autopsy in suspected ca

23 ding a mechanism for molecular detection and interrogation at the ring-frame interface.

24 or entities diagnosed in children, including interrogations at the level of the genome, epigenome, an

25 During the interrogation, bases in the dsDNA attempt to form Watson

26 selves through differential responses to its interrogation between stable and unstable substrates.

27 , of dynamical DNA distortions during search/interrogation beyond base pair breathing.

28 timore, Maryland) underwent CIED removal and interrogation by an electrophysiologist for clinical ale

29 arifies some molecular aspects of the genome interrogation by CRISPR RNA-guided Cas9 proteins.

30 o retain the structural integrity of MPs for interrogation by electrospray ionization-ion mobility sp

31 porating DNA nanoswitches to enable repeated interrogation by force of single molecular pairs, we dem

32 otospacer base pairs allowing initial target interrogation by guide RNA.

33 While the range of proteins amenable to interrogation by HDX MS continues to expand at an accele

34 he clinical relevance of the former warrants interrogation.Clinical Trials Registration.

35 mplexes, assigned as search complex (SC) and interrogation complex (IC), both at target lesions and u

36 tween August 2005 and January 2014 with CIED interrogation data following RT at an academic cancer ce

37 Here, in vitro and in vivo interrogation demonstrate that DNA-PKcs functions as a s

38 Functional interrogation demonstrated altered cytokine responsivene

39 confined to two dimensions or limited to an interrogation depth of approximately 15 mum.

40 uctures, we used ultradeep confocal imaging (interrogation depths, >4 mm).

41 TSF-mediated genome interrogation distinguishes naturally recombination-cold

42 coupled with continuous (extrahelical) base interrogation during lesion search by DNA glycosylases.

43 tion, and enables massively parallel droplet interrogation for applications, such as monitoring react

44 een preimplant ambulatory monitoring and ICD interrogation for detecting NSVT was poor (kappa=0.18).

45 dia project, we performed an unbiased global interrogation for the presence of a panel of 740 viruses

46 gning more versatile microfluidics, cellular interrogation holds promise as a systematic strategy tha

47 trait domains that are candidates for joint interrogation in future genetic studies (for example, la

48 ing this genetic marker offers direction for interrogation in subsequent genomic and experimental stu

49 ecision-cut slices of in vivo tumours permit interrogation in vitro of heterogeneous cells from solid

50 Here we use physiological and genetic interrogations in D. melanogaster to uncover the 'glucom

51 pment of improved reaction conditions and an interrogation into the fate of the metal center during t

52 ogies have enabled an unprecedented level of interrogation into the impact of DNA variation (genotype

53 Further interrogation into this class of therapy is warranted.

54 Theoretical interrogations into correlations based on ring size and

55 ese data show that T-REX allows quantitative interrogations into the extent to which the Nrf2 transcr

56 o fabricate simple MCF interferometers whose interrogation is carried out with light sources, detecto

57 RNA "seed" sequence required for initial DNA interrogation is preordered in an A-form conformation.

58 t the development towards a space-compatible interrogation laser system for a strontium lattice clock

59 evelopment of their components including the interrogation lasers of the clock transitions towards be

60 Spectral interrogation method is used for the characterization of

61 Spectral interrogation method is used for the characterization of

62 or the integration of multiple materials and interrogation modalities into neural probes.

63 ms have turned to either angular or spectral interrogation modes, which both offer very accurate real

64 ents Rad4 interconverting between search and interrogation modes.

65 trategies to enhance precision in biological interrogation, modulation and in therapy.

66 actile dysfunction at a level of noninvasive interrogation not previously available in humans.

67 Through interrogation of >10,000 organoids, we systematically op

68 Interrogation of a "druggable" pocket in the second zinc

69 Interrogation of a dataset comprising new environmental

70 Through interrogation of a genome-wide association study, we exa

71 Interrogation of accessory elements revealed that each c

72 f caspase and granzyme biosensors will allow interrogation of additional features of granzyme activit

73 Given the insights already gained from the interrogation of African genomes, it is imperative to co

74 This study represents the first metagenomic interrogation of Antarctic permafrost and polar cryptoen

75 More generally, this outcome suggests that interrogation of bioactive natural products is likely to

76 s strong potential for molecular studies and interrogation of biological functions.

77 lular processes and facilitate unprecedented interrogation of biological systems.

78 molecular nanoscopy are greatly desired for interrogation of biological, organic, and inorganic obje

79 resonator arrays and nanodiscs enables rapid interrogation of biomolecular binding interactions at mo

80 d, microfluidics offers a ready platform for interrogation of biophysical properties.

81 ience tools that have enabled high-precision interrogation of brain circuitry linked with REM sleep c

82 issue response to achieve chronic multimodal interrogation of brain circuits with high fidelity.

83 uencing technology to permit high-throughput interrogation of brain circuits.

84 h-throughput monitoring technologies enables interrogation of cancer samples at various levels of cel

85 tical functional role for type I IFNs led to interrogation of candidate innate immune sensing pathway

86 Replication and interrogation of causal relationships are needed to subs

87 multicomponent imaging and enable the direct interrogation of cell networks not currently possible wi

88 surements of individual cells as well as the interrogation of cell population heterogeneity.

89 plicable to a range of systems, enabling the interrogation of changes in a protein's conformation req

90 roduce a flexible method for high-resolution interrogation of circuit function, which combines simult

91 clinical utility of BBBs, allowing in depth interrogation of clinically relevant CTCs.

92 has enabled the development of tools for the interrogation of complex biological systems.

93 ly, retention of sample architecture enables interrogation of complex environments such as cellular c

94 ide unprecedented opportunities for detailed interrogation of complex genomic loci, examples of which

95 s approach permits more detailed single-cell interrogation of complex organs and tissues.

96 Interrogation of deep-sequencing data from MYB-overexpre

97 Spatial information is critical to the interrogation of developmental and tissue-level regulati

98 he use of induced pluripotent stem cells for interrogation of disease pathophysiology, analysis of dr

99 GS)-based technologies allow for genome-wide interrogation of diverse biological processes.

100 we report the synthesis and electrochemical interrogation of DNA-like molecular wires.

101 Moreover, further genetic interrogation of ductal carcinoma in situ might lead to

102 ssion quantitative trait locus analyses, and interrogation of Encyclopedia of DNA Elements, Roadmap,

103 genetic pharmacology toolkit allows scalable interrogation of endogenous GABA(A) receptor function wi

104 ystem that allows for the identification and interrogation of ensembles of neurons.

105 Interrogation of environmental microbial communities com

106 Advancing technology allowing genome-scale interrogation of epigenetic marks provides a rapidly exp

107 Interrogation of established autoantigens revealed highl

108 Thus, through genomic interrogation of experimental endotoxemia, we identified

109 C.2b, 3C.3, 3C.3a, and 3C.3b is based on the interrogation of five single nucleotide polymorphisms (S

110 e analysis pipeline, permitting quantitative interrogation of functional implications of heterogeneou

111 h-throughput, flexible and long-term optical interrogation of functionally defined neural circuits wi

112 a comprehensive comparative transcriptomics interrogation of gene expression among floral organs of

113 ess into an era in which the high-throughput interrogation of gene expression is commonplace and our

114 Systematic interrogation of gene function requires the ability to p

115 s biology approach based on the assembly and interrogation of gene regulatory networks, or interactom

116 s, which will allow for genetic analysis and interrogation of gene-environment interactions.

117 Interrogation of genes induced in the absence of Rev-erb

118 reens are powerful tools for high-throughput interrogation of genome function, but can be confounded

119 Interrogation of genome-wide gene expression in virgin a

120 flexible, giving a choice of algorithms for interrogation of genomes with motifs from many public so

121 h post-marketing surveillance or through the interrogation of healthcare databases.

122 Map to assist in exploration and statistical interrogation of high-dimensional complex "omics" data i

123 The interrogation of highly diverse repertoires of heterogen

124 Our observations present a molecular-scale interrogation of host-guest interactions in a disordered

125 l only be discovered by direct physiological interrogation of human astrocytes.

126 Interrogation of human cancer gene expression data revea

127 These 3D cultures should allow a detailed interrogation of human cortical development, function an

128 ic resonance (DT-CMR) may enable noninvasive interrogation of in vivo cardiac microstructural dynamic

129 Functional interrogation of individual antibodies (Antibodyomics9)

130 of 1 using purified enzymes and biochemical interrogation of individual biochemical steps, we show t

131 MSI, images are created through a grid-wise interrogation of individual spots by mass spectrometry a

132 g gate-controlled charging and spectroscopic interrogation of individual tetrafluoro-tetracyanoquinod

133 g technologies have facilitated the agnostic interrogation of insect vector genomes, giving medical e

134 Interrogation of international cohorts identified additi

135 Interrogation of intracellular Ca(2+) handling highlight

136 Systematic interrogation of iron flux determined that CSCs preferen

137 Direct interrogation of iron uptake demonstrated that CSCs pote

138 d may offer a valuable research tool for the interrogation of KATP channel function in health and T2D

139 In the present work, the structural interrogation of kinetically trapped intermediates of cy

140 Interrogation of knockout mouse phenotype resources prov

141 Interrogation of known transcription factor-lncRNA inter

142 This technique allows interrogation of large volumes intact brain samples for

143 This study motivates the interrogation of larger samples with full genome coverag

144 The lack of systematic interrogation of late development leaves large aspects o

145 on scheme for fast online mass spectrometric interrogation of levitated droplets is presented.

146 rk to recent developments, we review how the interrogation of LHA cells and circuits is contributing

147 on in a minimally invasive manner by optical interrogation of light-sensitive reporters and actuators

148 Our study provides a framework to guide the interrogation of macrophage phenotypes in the context of

149 Interrogation of mechanism showed that testosterone regu

150 Here we provide a systematic interrogation of mechanisms by which single amino acid c

151 electron transfer (PeT) trigger for optical interrogation of membrane voltage.

152 Techniques are available that allow the interrogation of memory B cell response to pathogen re-e

153 We establish its efficiency for high-density interrogation of methylome variability by systematic com

154 owerful tool for the systematic atomic-scale interrogation of molecular adsorbates.

155 and natural product libraries, allowing the interrogation of more diverse chemical space in efforts

156 Informatic interrogation of mRNA sequence databases revealed upregu

157 Interrogation of murine cytomegalovirus (MCMV)-encoded c

158 Systematic interrogation of mutation or protein modification data i

159 In addition to an all-optical interrogation of nanoscale mechanical properties, our re

160 g the 1970s and beyond set the stage for the interrogation of nearly every step in the reproductive c

161 Optogenetic interrogation of neural pathways relies on delivery of l

162 ion with focused light beams, enable precise interrogation of neuronal function, even at the level of

163 d here is generally applicable to functional interrogation of non-coding genomic elements.

164 offer investigators a toolkit for functional interrogation of not only protein-coding genes but also

165 DESI enabled the direct, rapid, native state interrogation of oil samples on steel surfaces without s

166 web-based platform that facilitates the easy interrogation of omics datasets holistically to improve

167 Furthermore, continued interrogation of oncogenes in benign developmental disor

168 This work enables the interrogation of other bacterial acyltransferases' struc

169 ional preference, and X-ray crystallographic interrogation of our model systems did not suggest the p

170 Further interrogation of our previously described microarray dat

171 This is optimally done by interrogation of paired H chain V region (VH) and L chai

172 t of AF during follow-up was identified from interrogation of permanent pacemakers.

173 The Omni-ATAC protocol enables the interrogation of personal regulomes in tissue context an

174 capture Hi-C (PCHi-C) allows the genome-wide interrogation of physical interactions between distal DN

175 ovel noninvasive techniques can add detailed interrogation of plaque composition, activity, and overa

176 ovided 1 new diagnostic finding, and allowed interrogation of posited disease genes.

177 oach for bisulfite-converted DNA that allows interrogation of pre-defined genomic locations, allowing

178 probes into proteomic workflows enables the interrogation of protein activity, rather than abundance

179 llular function, however, tools enabling the interrogation of protein dynamics within native lipid en

180 Doppler interrogation of pulmonary artery flow may provide an in

181 les simultaneous fluorescence and absorbance interrogation of rapidly moving droplets in a fully auto

182 ll library assay that affords multiparameter interrogation of rare Ag-reactive CD4(+) T cells was app

183 ptide phage library using the phage-assisted interrogation of reactivity method.

184 e here a technique which is suitable for the interrogation of regions at specified distances below th

185 sed multiplex strategy for direct functional interrogation of RNA cis-regulatory elements in a native

186 allowing for the first time a chemical-based interrogation of RNA splicing processes.

187 CryptSplice interrogation of sequence data from six individuals with

188 n of Mt/AFM-SECM enables the electrochemical interrogation of several hundreds of individual nanodots

189 Spatiotemporal interrogation of signal transduction at the single-cell

190 nts covering the biological response permits interrogation of signaling through thousands of quantifi

191 Interrogation of single SFs with subcellular laser ablat

192 for high-throughput quantitative volumetric interrogation of spatially-irregular and friable tissue

193 Finally, interrogation of stem-cell-derived motor neurons produce

194 Using a multimodal, circuit-level interrogation of striatal-cortical connections, it was d

195 oaches have opened the way for comprehensive interrogation of such orchestrated responses.

196 y, AK023948 is upregulated in breast cancer; interrogation of TCGA data set indicates that upregulati

197 Interrogation of the 5q trans-effects against the Librar

198 Bioinformatic interrogation of the acetylome from diabetic animals sho

199 Interrogation of the Akt signaling pathway suggested tha

200 echanism and serves as a launching point for interrogation of the biology of specific lincRNAs in car

201 Importantly, interrogation of the Cancer Genome Atlas breast invasive

202 in mice and represents a novel approach for interrogation of the cellular and molecular mechanisms u

203 behavior and provides an avenue for refined interrogation of the circuits involved in human memory.

204 Interrogation of the clinical record of 23 relapsed HCL

205 pamine (DA) release in the retina allows the interrogation of the complex neural circuits within this

206 Interrogation of the current vs time (i-t) traces when t

207 open access, web-based interface for further interrogation of the data.

208 ge and cellular compartment to focus further interrogation of the drivers of lymphoid cell loss with

209 g the 7 surviving affected individuals, with interrogation of the entire genome excluding other poten

210 In vivo interrogation of the function of genes implicated in tum

211 These data provide a resource for the interrogation of the global molecular connections that l

212 Here, systematic interrogation of the HLA-G locus using massively paralle

213 treatment with Rova-T based on a noninvasive interrogation of the in vivo status of DLL3 expression u

214 Structural interrogation of the linear and macrocyclic peptides usi

215 However, direct interrogation of the link between this putative synaptic

216 To permit the interrogation of the macrophage pathogen response pathwa

217 Here we report a detailed interrogation of the mechanism of TRL lowering by the AP

218 Under these conditions, interrogation of the N. europaea proteome revealed incre

219 volution in genetic technologies has allowed interrogation of the nuclear genome in a manner that has

220 Finally, interrogation of the Oncomine(TM) database suggests that

221 identifies a model that will permit in depth interrogation of the pathogenesis of rheumatoid arthriti

222 Interrogation of the PEDF sequence identified a conserve

223 Interrogation of the protein/DNA interface by DNA footpr

224 In contrast, the interrogation of the quiescent memory B cell compartment

225 Here, we report direct experimental interrogation of the reaction coordinate for the [Formul

226 Our interrogation of the reaction mechanism suggests a disul

227 f substituted radicals allows for the direct interrogation of the rebound process, providing insight

228 Further interrogation of the receptor tyrosine kinase activity i

229 (CA II) inhibitor design that enables close interrogation of the regions of the CA active site where

230 Based on quantitative interrogation of the relationship between SERRS performa

231 ls therefore provide a foundation for future interrogation of the relationships between chromosome st

232 C virus (HCV) replication, yet a systematic interrogation of the repertoire of miRNAs impacting HCV

233 periments in mouse barrel cortex demonstrate interrogation of the same neuronal population during dif

234 Molecular interrogation of the sciatic nerve reveals that aged Sch

235 d (Leydig cell AR knockout mice), permitting interrogation of the specific roles of autocrine Leydig

236 e exposure in mice, enabling pharmacological interrogation of the specificity of the offspring respon

237 ght promising new research tools for ongoing interrogation of the stem cell-material interface.

238 selective inhibitors as chemical probes for interrogation of the structural and dynamic features tha

239 ere we present a biophysical and biochemical interrogation of the structure of the full length CTD of

240 Here, we describe a high-resolution interrogation of the transcriptomes (available at www.dd

241 tracing of mPFC projections and optogenetic interrogation of their synaptic connections with neurons

242 n, preclinical models of ELNs are needed for interrogation of these chemokines.

243 ic modeling, hold promise for the systematic interrogation of these complex pathways.

244 all GTPases and protein phosphorylation make interrogation of these key processes of great importance

245 Chemical interrogation of these primary human specimens revealed

246 fining the "commitment proteome." Functional interrogation of this data set identified Nek-related ki

247 Functional interrogation of this network uncovered a critical RhoA/

248 Microarrays have allowed the interrogation of thousands of common genetic markers in

249 l challenges, but is significant for optical interrogation of three-dimensional objects.

250 f publicly available NGS data for the direct interrogation of transcriptional programmes that regulat

251 Systematic interrogation of tumor-infiltrating lymphocytes is key t

252 spatial changes in protein expression before interrogation of tumour slices by pharmacological or oth

253 This detailed interrogation of tyrosines in HCA II by NMR and neutron

254 However, real-time interrogation of unstable plaque remains an unmet clinic

255 Raman spectroscopy also allows simultaneous interrogation of various pigments in plants.

256 The results should allow facile interrogation of various targets by type I-E CRISPR-Cas

257 The utilization of DEX screening allowed the interrogation of very large compound libraries (10(11) u

258 monstrate the mechanistic value of stringent interrogation of well-defined sets of genes as a complem

259 lastoma on the basis of rigorous statistical interrogation of what is, to the best of our knowledge,

260 lastoma on the basis of rigorous statistical interrogation of what is, to the best of our knowledge,

261 molecules thus opens the door to functional interrogations of intracellular physicochemical paramete

262 -binding proteins to minimize time-consuming interrogations of non-target sites.

263 ivity or filament formation and allowing for interrogations of respiratory syncytial virus virion ass

264 ssful application of HiTES will allow future interrogations of the biological regulation and chemical

265 scaling, can be probed through quantitative interrogations of the properties of morphogen gradients

266 of kinases would enable fine spatiotemporal interrogation or manipulation of these various functions

267 Adverse events were identified by ICD interrogations, patient reports, and medical charts.

268 particles/cells as they pass through a laser interrogation region.

269 eg suppressive function, and pharmacological interrogation revealed a set of genes having causative e

270 Genomic and molecular interrogation reveals an atypical VEGF-based vasculogene

271 In surface interrogation scanning electrochemical microscopy (SI-SE

272 nvestigation of the CoPi catalyst by surface interrogation scanning electrochemical microscopy (SI-SE

273 ong period grating (LPG) and a basic optical interrogation scheme using off the shelf components is u

274 After almost a century of scientific interrogation, significant progress has been made in und

275 Chemical interrogation spotlights IAV HA as a major druggable tar

276 followed by reversible transitions into DNA interrogation states.

277 ht to elucidate the mechanism of initial DNA interrogation steps that precede the pairing of target D

278 , chemogenetic, genetic, and pharmacological interrogation suggested that downregulation of cortico-S

279 ay time between substrate generation and tip interrogation (tdelay) is crucial because tdelay defines

280 The sensor works on the wavelength interrogation technique and is capable of detecting trac

281 tammetry (from 0 to 0.8 V) was chosen as the interrogation technique to impose the exhaustive oxidati

282 ltammetry or chronoamperometry as the sensor interrogation technique, all three sensors, each passiva

283 inity pulldown, a gold-standard in vitro PPI interrogation technique, to perform nanoscale pulldowns

284 This validates electromagnetic interrogation techniques as a potential detection tool f

285 tical approach provides HT means of cellular interrogation, that is, allows for dynamic testing of >6

286 The CIED interrogation, the manufacturer's technical analysis, an

287 Combined with the long interrogation times afforded by ion traps, a broad range

288 6 family members may be hidden by inadequate interrogation timescales, and that revelation of such ac

289 ta transmission coupled with automated image interrogation to assure protocol adherence.

290 Here, using an array of intact-brain circuit interrogation tools, including CLARITY, COLM, optogeneti

291 ut (HT), cellular-level electrophysiological interrogation tools.

292 pecial nuclear materials is by use of active interrogation using an external radiation source.

293 Here, we develop a method of cellular interrogation using programmable microfluidic devices wh

294 iva contains molecular information worthy of interrogation via EWAS.

295 Through combinatorial interrogation, we find that simultaneous repression of m

296 Through this comprehensive interrogation, we succeeded in isolating the cloche gene

297 Predefined outcomes for interrogation were all-cause mortality, composite end po

298 The two models that survived the double interrogation were mathematically different but schemati

299 Submillisecond interrogation with preferential stalling at cognate site

300 eriment), enabling comprehensive statistical interrogations with respect to underlying tunneling char