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3 lly higher under canopies compared to canopy interspaces, but converged toward the end of the study.
4 cribe movement as a series of straight steps interspaced by turns, and implicitly assume no turn cost
5 ) single-scan spectra reveals a preferential interspacing for the components and their anticorrelatio
6 ected adjacent GGAA repeats by converting an interspaced GGAT motif into a GGAA motif, thereby increa
7 , the inspiratory intercostal muscles in all interspaces in anaesthetized dogs were severed so that t
8 e dermal destruction as well as in important interspace necrosis in control animals, whereas burn pro
10 d uniform film structure, with no detectable interspaces or micropores; probiotic inclusion did not s
11 scovery of the bacterial clustered regularly interspaced palindromic repeat (CRISPR) system and its s
12 Here we develop pooled clustered regularly interspaced palindromic repeat (CRISPR)-Cas9 guide RNA l
13 w the history of CRISPR (clustered regularly interspaced palindromic repeat) biology from its initial
15 on architecture based on clustered regularly interspaced palindromic repeats (CRISPR) system and exam
17 rammable nuclease termed clustered regularly interspaced palindromic repeats (CRISPR)-associated prot
19 AMPK in RPE cells using Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 did not ab
20 like effector nucleases, clustered regularly interspaced palindromic repeats (CRISPR)/CRISPR-associat
23 ococcus pyogenes CRISPR (clustered regularly interspaced palindromic repeats) pathway, requiring only
24 The prokaryotic CRISPR (clustered regularly interspaced palindromic repeats)-associated protein, Cas
25 RATIONALE: CRISPR/Cas9 (clustered regularly interspaced palindromic repeats/CRISPR-associated protei
26 a-2), using CRISPR/Cas9 (clustered regularly interspaced palindromic repeats/CRISPR-associated) homol
28 protection was associated with an increased interspace perfusion with EPO 500, but not with EPO 2500
29 mental stress on pinon survival: Survival of interspace pinon juveniles was positively associated wit
33 uence typing (MLST), and clustered regularly interspaced short palindromic repeat (CRISPR) analysis.
34 ALEs) and the RNA-guided clustered regularly interspaced short palindromic repeat (CRISPR) associated
38 0-base-pair lengths into clustered regularly interspaced short palindromic repeat (CRISPR) loci as sp
39 smid) DNA fragments into clustered regularly interspaced short palindromic repeat (CRISPR) loci in pr
40 DNA are integrated into Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) loci, prov
43 pared RNAi technology to clustered regularly interspaced short palindromic repeat (CRISPR)-based knoc
45 rinciple work shows that clustered regularly interspaced short palindromic repeat (CRISPR)-Cas system
46 RNA (siRNA) knockdown or clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9 genom
47 in endothelial cells by clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9 revea
48 genome editing with the clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9 syste
49 ut (KO) cells by using a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9 syste
50 present study, we used a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9 techn
51 virus antigenicity, and clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9-media
52 synthetic constructs and clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9-media
53 a or lacking Cdc42 using clustered regularly interspaced short palindromic repeat (CRISPR)-caspase 9
55 ny prokaryotes, type III clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-ass
56 he bacterial and archeal clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-ass
58 new technologies such as clustered regularly interspaced short palindromic repeat (CRISPR)-derived ge
59 The recently discovered clustered regularly interspaced short palindromic repeat (CRISPR)-mediated v
60 rokaryotic immune system clustered regularly interspaced short palindromic repeat (CRISPR)/Cas evolve
61 of analysis of cellular clustered regularly interspaced short palindromic repeat (CRISPR)/Cas loci a
62 luding the emergence of clustered regulatory interspaced short palindromic repeat (CRISPR)/Cas-based
63 stine, a Cryptosporidium clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 syste
65 tor nuclease (TALEN) and clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 techn
66 2 in hearing, we applied clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9-media
67 MUC1-C with silencing by clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-ass
68 r nucleases (TALENs) and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-ass
71 gies in combination with clustered regularly-interspaced short palindromic repeat (CRISPR)/CRISPR-ass
73 an insertion in the 3rd clustered regularly interspaced short palindromic repeat (CRISPR3) in M. xan
77 , the RNA-guided CRISPR (clustered regularly interspaced short palindromic repeat)-associated Cas9 nu
78 e Cmr/type III-B CRISPR (clustered regularly interspaced short palindromic repeat)-Cas (CRISPR-associ
80 that utilize the CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9 (CRISPR-assoc
83 t diabetes using CRISPR (clustered regularly interspaced short palindromic repeat)/Cas9-mediated geno
84 se using the CRISPR-Cas (clustered regularly interspaced short palindromic repeat, CRISPR associated)
85 ere, we packaged SaCas9 (clustered regularly interspaced short palindromic repeat-associated 9 from S
86 genetically modified by clustered regularly interspaced short palindromic repeat-Cas9 (CRISPR-Cas9)
87 ase from the CRISPR-Cas (clustered regularly interspaced short palindromic repeat-CRISPR-associated)
88 the tool CRISPR-ERA, for clustered regularly interspaced short palindromic repeat-mediated editing, r
92 like effector nucleases, clustered regularly interspaced short palindromic repeat/CAS9 RNA-guided nuc
93 onally ablated using the clustered regularly interspaced short palindromic repeat/Cas9 technology.
94 CN2 knockout by means of clustered regularly interspaced short palindromic repeat/CRISPR-associated 9
95 lease from the microbial clustered regularly interspaced short palindromic repeats (CRISPR) adaptive
96 interference, as well as clustered regularly interspaced short palindromic repeats (CRISPR) and assoc
97 et al, 2014), as well as clustered regularly interspaced short palindromic repeats (CRISPR) and assoc
98 une system consisting of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISP
103 NA endonuclease found in clustered regularly interspaced short palindromic repeats (CRISPR) bacterial
108 NA-guided, RNA-targeting clustered regularly interspaced short palindromic repeats (CRISPR) effector
109 tely using an engineered clustered regularly interspaced short palindromic repeats (CRISPR) endoribon
110 alyses revealed that the clustered regularly interspaced short palindromic repeats (CRISPR) genes as
111 ghput approach that uses clustered regularly interspaced short palindromic repeats (CRISPR) interfere
115 s for producing multiple clustered regularly interspaced short palindromic repeats (CRISPR) single gu
116 erfering RNA (siRNA) and clustered regularly interspaced short palindromic repeats (CRISPR) studies d
117 Using the bacterial clustered regularly interspaced short palindromic repeats (CRISPR) system, w
118 evoted to three distinct clustered regularly interspaced short palindromic repeats (CRISPR) systems m
119 cell model of CHS using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technolog
121 or nucleases (TALEN) and clustered regularly interspaced short palindromic repeats (CRISPR) with CRIS
123 coded within CRISPR-cas [clustered regularly interspaced short palindromic repeats (CRISPR)-associate
124 ) with nuclease-inactive clustered regularly interspaced short palindromic repeats (CRISPR)-associate
125 hly effective autonomous Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associate
126 -cell gene editing using clustered regularly interspaced short palindromic repeats (CRISPR)-associate
127 on of a trait gene using clustered regularly interspaced short palindromic repeats (CRISPR)-associate
130 ng using bacterial Type II cluster regularly interspaced short palindromic repeats (CRISPR)-associate
132 ted virus (AAV)-mediated clustered regularly interspaced short palindromic repeats (CRISPR)-associate
133 the nuclear dynamics of clustered regularly interspaced short palindromic repeats (CRISPR)-associate
134 ystem, which is based on clustered regularly interspaced short palindromic repeats (CRISPR)-associate
136 sequencing (RNA-seq) and clustered regularly interspaced short palindromic repeats (CRISPR)-based per
137 n from a high-efficiency Clustered regularly interspaced short palindromic repeats (CRISPR)-based phe
142 9 nucleases derived from clustered regularly interspaced short palindromic repeats (CRISPR)-Cas syste
144 hat the machinery of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 bact
145 ssociated virus (AAV) of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 endo
146 The recently discovered clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 endo
147 wo key components of the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 geno
148 r nucleases (TALENs) and clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 nucl
149 ent activity (GenERA), a clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 plat
152 d the recently developed clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 syst
153 was used to deliver the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 syst
154 s (TALENs) or RNA-guided clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 toge
155 f endogenous proteins by clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9-medi
156 gene was knocked out by clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9.
158 to deliver a functional clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-as
161 ne disruption induced by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-As
162 pabilities, we developed clustered regularly interspaced short palindromic repeats (CRISPR)-Display (
163 lin B1 gene promoter via clustered regularly interspaced short palindromic repeats (CRISPR)-enzymatic
164 ase that participates in clustered regularly interspaced short palindromic repeats (CRISPR)-mediated
165 The high efficiency of clustered regularly interspaced short palindromic repeats (CRISPR)-mediated
168 ith S-HSCR, and used the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene
169 genetic information with clustered regularly-interspaced short palindromic repeats (CRISPR)/Cas9 geno
170 r nucleases (TALENs) and clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 in m
171 cleases (TALENs) and the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 syst
172 The barcode, an array of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 targ
173 luding in particular the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 tech
174 d the recently developed clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 tech
176 genomic MARCH6 locus by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-medi
177 intestinal tissue using clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-medi
178 , Enhancer L Strikingly, clustered regularly-interspaced short palindromic repeats (CRISPR)/Cas9-medi
179 or nuclease (TALEN)- and clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-stim
184 he recipient cells using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
187 tuted nuclease-deficient clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
189 r genome editing using a clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
190 the type II prokaryotic clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
191 immune defenses, termed clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
192 sed transgenesis and the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
195 ive cotransformation and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
196 in macrophages using the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-as
197 ions were generated with clustered regularly interspaced short palindromic repeats (CRISPR-Cas9)-medi
200 to gene knockouts using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) and Tran
202 small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associat
203 fense system composed of clustered regularly interspaced short palindromic repeats (CRISPRs), togethe
204 e of virulence genes and clustered regularly interspaced short palindromic repeats (CRISPRs), we prev
205 contrast to that of the clustered regularly interspaced short palindromic repeats (CRISPRs), which t
207 ger nucleases (ZFNs) and clustered regularly interspaced short palindromic repeats (CRISPRs)/Cas9 are
209 ting, recent advances in clustered regularly interspaced short palindromic repeats and clustered regu
211 ) analysis (MLVA), (iii) clustered regularly interspaced short palindromic repeats combined with mult
215 une systems use CRISPRs (clustered regularly interspaced short palindromic repeats) and CRISPR-associ
217 a core family of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) associated protei
218 ved from type II CRISPR (clustered regularly interspaced short palindromic repeats) bacterial immune
220 (where CRISPR indicates clustered regularly interspaced short palindromic repeats) gene mutation, to
221 om the microbial CRISPR (clustered regularly interspaced short palindromic repeats) immune system has
222 invader DNA into CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) loci, termed 'Ada
225 archaea rely on CRISPR (clustered regularly interspaced short palindromic repeats) RNA-guided adapti
228 has two complete CRISPR (clustered regularly interspaced short palindromic repeats) systems that serv
229 used engineered CRISPR (clustered regularly interspaced short palindromic repeats) to efficiently mu
230 mplexes that use CRISPR (clustered regularly interspaced short palindromic repeats)-associated (Cas)
231 ve immunity uses CRISPR (clustered regularly interspaced short palindromic repeats)-associated (Cas)
232 ng involving the CRISPR (clustered regularly interspaced short palindromic repeats)-associated (Cas)
233 programming the CRISPR (clustered regularly interspaced short palindromic repeats)-associated nuclea
235 hat the type I-E CRISPR (clustered regularly interspaced short palindromic repeats)-Cas system of Esc
236 , especially the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 (CRISPR-asso
237 riants using the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 system.
239 utic efficacy of CRISPR (clustered regularly interspaced short palindromic repeats)-mediated genome e
240 e II prokaryotic CRISPR (clustered regularly interspaced short palindromic repeats)/Cas adaptive immu
241 e the use of the CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-asso
242 tor nuclease and CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-asso
243 disruption using CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-asso
244 Recently, the CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 system, firs
245 e effector nucleases and clustered regularly interspaced short palindromic repeats, provide a platfor
246 palindromic repeats and clustered regularly interspaced short palindromic repeats-associated 9 techn
247 ndromic repeats (CRISPR)/clustered regularly interspaced short palindromic repeats-associated protein
248 rats using CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-associated protein
249 e effector nucleases, or clustered regularly interspaced short palindromic repeats-based nucleases) r
250 hese are the CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR associated)
252 tems, called CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR associated)
253 RNA-guided CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR-associated
255 ased on the CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR-associated
257 mmune system CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated)
259 ector protein (TALE) and clustered regularly interspaced short palindromic repeats/Cas9 transcription
261 We used CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR associated
262 (eEF-2) gene] using the Clustered Regularly Interspaced Short Palindromic Repeats/Crispr associated
264 taking advantage of the clustered regularly interspaced short palindromic repeats/CRISPR-associated
265 g seed development using Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated
267 on using the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated
268 ystem is the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated
271 by the emergence of the clustered, regularly interspaced, short palindromic repeat (CRISPR) technolog
272 me targeting by type II clustered, regularly interspaced, short palindromic repeat (CRISPR)-Cas9 nucl
273 ctor nucleases, and the clustered, regularly interspaced, short palindromic repeat/Cas system) and de
275 ents of the prokaryotic clustered, regularly interspaced, short palindromic repeats (CRISPR) loci hav
276 flies mutated using the clustered, regularly interspaced, short palindromic repeats (CRISPR) tool sho
277 c acids are silenced by clustered, regularly interspaced, short palindromic repeats (CRISPR)--CRISPR-
279 We report the use of clustered, regularly interspaced, short palindromic repeats (CRISPR)-associat
282 Genome editing with the clustered, regularly interspaced, short palindromic repeats (CRISPR)-Cas9 nuc
283 fectors (TALEs) and the clustered, regularly interspaced, short palindromic repeats (CRISPR)-Cas9 sys
284 iting based on type II, clustered, regularly interspaced, short palindromic repeats (CRISPR)-CRISPR-a
285 m bacteria [the type II clustered, regularly interspaced, short palindromic repeats (CRISPR)-CRISPR-a
288 r nucleases (TALENs) or clustered, regularly interspaced, short palindromic repeats (CRISPR/Cas9), re
291 lexes guided by CRISPR (clustered, regularly interspaced, short palindromic repeats) RNAs (crRNAs) to
292 ethod that uses CRISPR (clustered, regularly interspaced, short palindromic repeats) to build mapping
293 diting with the CRISPR (clustered, regularly interspaced, short palindromic repeats)-Cas9 platform is
294 ially used dual-CRISPR (clustered, regularly interspaced, short palindromic repeats)-Cas9 targeting t
297 oximately 3 nm in thickness), with a tunable interspace, we achieve 10 C charge/discharge rate with r
299 , the inspiratory intercostal muscles in all interspaces were severed in anaesthetized dogs, so that
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