ライフサイエンスコーパス: interstitium

1 cells and promote inflammation in the renal interstitium.

2 tween the urinary space and the hyperosmotic interstitium.

3 eas HeV initiated infection primarily in the interstitium.

4 tments are defined: the testis cords and the interstitium.

5 individuals and can gain access to the brain interstitium.

6 sors and LHX9 to the coelomic epithelium and interstitium.

7 or secreted ligands that traffic through the interstitium.

8 f amyloid-beta (Abeta) peptides in the brain interstitium.

9 ewer F4/80 positive cells in the peritubular interstitium.

10 the accumulation of scar tissue in the lung interstitium.

11 P (positional isomer of 3',5'-cAMP) into the interstitium.

12 aces at the same time limiting flow into the interstitium.

13 inant involvement of glomeruli and medullary interstitium.

14 RESUS + VH favors fluid flux into the interstitium.

15 yaluronan on diffusive hindrance through the interstitium.

16 hways between connected cells and within the interstitium.

17 rs is limited by diffusion through the tumor interstitium.

18 iderable leakage of the probe into the islet interstitium.

19 e examples of stromal cells within the renal interstitium.

20 net fatty acid flow between the cell and the interstitium.

21 lin may promote its own movement into muscle interstitium.

22 the reduced tonicity of the renal medullary interstitium.

23 AM cells, that form nodules in the pulmonary interstitium.

24 was mainly scattered in damaged tubules and interstitium.

25 eases the concentration of NEi in the muscle interstitium.

26 on of tubular cells through the TBM into the interstitium.

27 the tubular epithelium and excluded from the interstitium.

28 of potential tubular stem cells in the renal interstitium.

29 sonance (CMR) can assess abnormal myocardial interstitium.

30 r compartment into the noninflamed pulmonary interstitium.

31 Sertoli cells and to a lesser extent in the interstitium.

32 MP-9 were concomitantly induced in the renal interstitium.

33 ycocalyx was significantly lower than in the interstitium.

34 st likely due to increased mixing within the interstitium.

35 y located within the mesangium and the renal interstitium.

36 esting activation of eosinophils in the lung interstitium.

37 oping coronary vasculature in the myocardial interstitium.

38 vessels and colocalized with vimentin in the interstitium.

39 with calcium, cross the endothelium into the interstitium.

40 ion of toxic materials from the lumen to the interstitium.

41 vement and/or activation within the inflamed interstitium.

42 ed by persistence of thickened intersaccular interstitium.

43 mplex II-positive macrophages in the ovarian interstitium.

44 e is little accumulation of potassium in the interstitium.

45 olve both the cardiomyocytes and the cardiac interstitium.

46 as myofibroblasts accumulate in the tubular interstitium.

47 es were unable to extravasate into the tumor interstitium.

48 allowed access of the 160 kD Crry-Ig to the interstitium.

49 ore biopsies had lymphocytes in 5-30% of the interstitium.

50 olecules from the bloodstream into the tumor interstitium.

51 e were predominantly restricted to the graft interstitium.

52 reased OPN mRNA and protein primarily in the interstitium.

53 iseases involving the airways, including the interstitium.

54 d transport of albumin from the blood to the interstitium.

55 partial reflection of hyaluronan by synovial interstitium.

56 n the peripheral lung tissue in the alveolar interstitium.

57 omes were able to extravasate into the tumor interstitium.

58 ssed in the endothelium of the glomerulus or interstitium.

59 tantial amounts of MP into the pericapillary interstitium.

60 n the relative volume of the alveolar septal interstitium.

61 une response that results in a damaged renal interstitium.

62 contribute to progenitor cells in the testis interstitium.

63 0 to 700 kDa or 10 to 200 nm into the kidney interstitium.

64 within lymph nodes (LNs) draining the tumor interstitium.

65 profile intermediate between epithelium and interstitium.

66 onal migration through cell barriers and the interstitium.

67 CXCL1 chemotactic gradient accurately in the interstitium.

68 n the immune cells that infiltrate the renal interstitium.

69 of infection, injury, and stress within the interstitium.

70 transport through the vasculature and tumor interstitium.

71 units, the nephrons, surrounded by the renal interstitium.

72 n of ammonium in the medullary and papillary interstitium.

73 lar total volume exclusion properties in the interstitium.

74 ge of the contrast agent into the islet cell interstitium.

75 of amyloid-beta peptide (Abeta) in the brain interstitium.

76 oth muscle actin-positive cells in the renal interstitium.

77 sion-dependent albumin shifts from plasma to interstitium.

78 cs and were significantly faster than in the interstitium.

79 t can permit passive accumulation into tumor interstitium.

80 ctor CD8(+) T cells within the infected lung interstitium.

81 regulating Abeta fibril growth in the brain interstitium.

82 ught to be too slow for an adaptation to the interstitium [3], is an important second route allowing

83 route to modulate solute transport from the interstitium according to biomechanical cues.

84 that microspheres can readily pass from the interstitium across the endothelium into the lumen of th

85 n that neural stem cells can penetrate tumor interstitium, actively migrating even to hypoxic tumor c

86 In murine renal interstitium after obstructive injury, tPA and alpha-SMA

87 n the nuclei of renal tubular epithelium and interstitium after obstructive injury.

88 d cells collectively accumulated in the lung interstitium along with the successful metastatic cells

89 (PMNs) from the vascular space into the lung interstitium and airspace is an early step in the host i

90 uited from the circulation and patrolled the interstitium and airspaces of the lung.

91 to the bronchoalveolar lavage fluid and lung interstitium and airway goblet cell metaplasia, smooth m

92 infiltration of inflammatory cells into the interstitium and airways, and production of inflammatory

93 lar TG2 colocalized with Sdc4 in the tubular interstitium and basement membrane, where TG2 also coloc

94 ts that non-satellite cell types from muscle interstitium and bone marrow also give rise to myonuclei

95 our locations (i.e. intracellular, membrane, interstitium and circulation) are similar: opsonization,

96 P is also released basolaterally, toward the interstitium and circulation, to inhibit tubular inflamm

97 chains or transthyretin (TTR) in the cardiac interstitium and conducting system, represent an importa

98 limit macrophage accumulation in the tubular interstitium and disease progression.

99 ge amounts of trypsinogen are present in the interstitium and drain via the portal and lymphatic circ

100 hog readout) in postnatal Six2creFrs2alphaKO interstitium and ectopic sonic hedgehog (Shh) in subsets

101 rier proteins Cp, like albumin in plasma and interstitium and Fatty Acid-Binding Proteins within endo

102 ve discovered molecular heterogeneity in the interstitium and have characterized new markers of disti

103 tes that were spatially confined to the lung interstitium and heterogenous in their expression of CD1

104 effect accompanied by a hypotonic medullary interstitium and impaired countercurrent multiplication.

105 fficking of T lymphocytes from the pulmonary interstitium and into the large airways, during the onse

106 activity exists within the human myocardial interstitium and is a dynamic process under conditions s

107 n with amber light acidified the surrounding interstitium and led to activation of endogenous ASIC1a

108 expansion of alpha-SMA-positive cells in the interstitium and loss of tubular area occur via encroach

109 in the extravascular compartment, within the interstitium and lymph, in health and disease, and we he

110 TR-dextran remained confined by surrounding interstitium and myofibroblasts.

111 When present, they are limited to the tubulo-interstitium and often subtle despite profound dysfuncti

112 , on both T-cell number in the glomeruli and interstitium and on cytokine expression characteristic o

113 uced T cell responses in the airway and lung interstitium and protection in B cell-depleted wild-type

114 ble clinicians and researchers to assess the interstitium and quantify ECM expansion using extracellu

115 semipermeable barrier between blood and the interstitium and regulates various critical biochemical

116 nsplanted into host rat testes, colonize the interstitium and subsequently differentiate in vivo.

117 eliminated, the putative SLCs colonized the interstitium and subsequently expressed 3betaHSD, demons

118 GF)-beta 1, particularly within the fibrotic interstitium and the fibroblastic focus, and prominently

119 both trans-endothelial migration to the lung interstitium and trans-epithelial migration into the air

120 ed to the capillary endothelium and neuronal interstitium and, in two cases, within the nucleus of th

121 sement membrane, were not found in the renal interstitium, and did not express alpha-smooth muscle ac

122 Phd3 were differentially expressed in renal interstitium, and heterozygous deficiency for Phd1 and P

123 phrogenic cortex, glomerular tufts, cortical interstitium, and medulla including vessels in the vasa

124 ed in interacinar capillaries (IAC), islets, interstitium, and small- and medium-size vessels.

125 d, microdialysis sampling of skeletal muscle interstitium, and stable isotope methodology, to assess

126 corbate concentrations expected in the brain interstitium, and was stimulated by cobalt ions.

127 ry arteries, veins, lymphatics, and the lung interstitium are all represented at the level of the sec

128 GPIb alpha-positive cells within the dermal interstitium are demonstrated to represent factor XIIIa-

129 ex cell-cell interactions among cells in the interstitium are involved in testis morphogenesis.

130 and prediction of drug delivery to the tumor interstitium are of critical importance in cancer chemot

131 ronevironment - both the vasculature and the interstitium - are needed to maximize the effects of che

132 a) and steroidogenic cells (Leydig and theca-interstitium) are two major somatic cell types in mammal

133 the salinity/tonicity of the renal medullary interstitium as a result of inhibition of active sodium

134 Spirochetes in the cardiac interstitium associated with collagen fibers and co-loca

135 flammatory response was present in the renal interstitium at 28 days postinfection, LPS and OmpL1 wer

136 ic col(V) in bronchoalveolar lavage and lung interstitium because of MMP-mediated matrix degradation.

137 evalent mononuclear cell infiltration in the interstitium beginning at day 2 p.i. and peaking at day

138 in expression in renal tubular cells and the interstitium but not glomeruli.

139 ing Ab had suppressed Smad activation in the interstitium but not in myocytes, and noncanonical (TGF-

140 ificant reduction of eosinophils in the lung interstitium but not in the airway lumen.

141 -positive cells are located within the renal interstitium, but are negative for Foxd1, an established

142 o bronchoalveolar lavage fluid and into lung interstitium, but CXCR2-/- mice reconstituted with CXCR2

143 sodium channel, and is pumped into the lung interstitium by basolaterally located Na/K-ATPase, thus

144 very and up to 34% as quantified in the lung interstitium by cytokeratin 18 immunostaining.

145 would be more easily cleared from the brain interstitium by diffusion than by bulk flow.

146 (+) channels (ENaC) and is extruded into the interstitium by Na,K-ATPase.

147 sinophilia (bronchoalveolar lavage fluid and interstitium) by half, indicating that CXCR4-mediated si

148 lular matrix (ECM) within the glomerulus and interstitium characterizes renal fibrosis, but the mecha

149 rolonged accumulation of eosinophils in lung interstitium concomitant with a delayed increase in eosi

150 tia, and 30+/-7 percent of such cells in the interstitium contained the Y-chromosomal marker, indicat

151 Inasmuch as myocardial interstitium contains angiotensinogen and angiotensin-co

152 oss the capillary endothelium from plasma to interstitium continues to be debated.

153 Volume fraction of interstitium correlated with creatinine clearance (r = -

154 d in which the NDL tumor cells and the tumor interstitium could no longer be detected.

155 ealed that the cells that accumulated in the interstitium derived from nephron progenitor cells and e

156 presenting delivery of the contrast to tumor interstitium, determined from the kinetic curves of GdDT

157 EPDCs, which colonize the cardiac interstitium during embryogenesis, massively differentia

158 ), PGE(2) and PGI(2), also accumulate in the interstitium during exercise, and breathing 40% O(2) abo

159 ent to establish bulk flow through the brain interstitium during infusion.

160 Water accumulation in the interstitium (edema) and the peritoneum (ascites) of nep

161 neutralization of CXCL2 but not CXCL1 in the interstitium effectively reduced neutrophil recruitment.

162 cells forming a network throughout the renal interstitium expressed macrophage-specific markers.

163 l flux cause unstable oxygen levels in tumor interstitium, extravascular oxygenation of R3230Ac mamma

164 to size-related molecular reflection at the interstitium-fluid interface.

165 of equilibration between microdialysate and interstitium for each probe to accurately estimate conce

166 raction of renal cortical volume occupied by interstitium from baseline to 5 years or ESRD from IF/TA

167 ATP is released into the interstitium from muscle fibres, at least in part throug

168 ing bone spicules, which limit the amount of interstitium from which mural myofibroblasts can be recr

169 of effector T cells from the vascular to the interstitium functions through a pertussis toxin-sensiti

170 pHLIP also maps the renal cortical interstitium; however, kidney accumulation can be reduce

171 levels, fluid and protein loss in pulmonary interstitium, impaired lung expansion, and alveolar-capi

172 T cells were present in tubules and tubular interstitium in acute rejection.

173 /around mast cells within the fibrotic renal interstitium in all samples.

174 yofibroblasts and macrophages in the tubular interstitium in Alport's syndrome mice and delays diseas

175 e IV collagen, were reduced in glomeruli and interstitium in anti-VLA-1-treated animals (P = 0.0006).

176 ADPKD, monocytes accumulate within the renal interstitium in association with increased levels of mon

177 t, in the heart, mast cells are found in the interstitium in close proximity to nerves and myocytes,

178 S2 protein increased in the renal interstitium in diabetes and regulated TGF-beta-mediated

179 hing of the epithelium and thickening of the interstitium in embryonic lungs.

180 n the endothelial capillary walls and neural interstitium in GBCA-injected rats, but not in control r

181 beta chain protein is primarily in the renal interstitium in healthy and regenerating kidney.

182 and of fibrillar collagen I in the adjacent interstitium in the dual infection may facilitate dissem

183 e morphologic characteristics of the cardiac interstitium in the hibernating human myocardium and eva

184 y epithelial cell layer and also in the lung interstitium in the sites of leukocytic infiltration tha

185 es loss of CTSK expression in the myocardial interstitium in vivo.

186 53), Fg immunoreactivity in the tubules and interstitium increased remarkably and was able to distin

187 Renal interstitium inflammatory infiltrates were observed in 5

188 lved in the movement of neutrophils from the interstitium into alveoli.

189 ion of megakaryocytic PP extensions from the interstitium into BM sinusoids and triggering the subseq

190 gression of inflammatory cells from the lung interstitium into the airway lumen is critical for the r

191 system that permits fluid to enter from the interstitium into the initial lymph channels but prevent

192 ux of an extracellular marker from the renal interstitium into the proximal tubule of the rat.

193 f CD4(+) T regulatory cells to the allograft interstitium is a final common pathway for metastable re

194 of the neutralizing superoxide flow into the interstitium is associated with the activation of mitoch

195 Infiltration of immune cells into the renal interstitium is characteristic of chronic inflammatory k

196 Leukocyte infiltration of the cortico-interstitium is characteristic of many forms of progress

197 The hyperosmolality in the renal medullary interstitium is of major importance as a driving force f

198 n, the principal component of the myocardial interstitium, is hypothesized to be essential for this m

199 ion and increased collagen deposition in the interstitium, is often considered an autoimmune disease.

200 uman hearts, LOXL2 is upregulated in cardiac interstitium; its levels correlate with collagen crossli

201 contrast reagent transfer between plasma and interstitium (K(trans)) and interstitial space volume fr

202 ure but did not appreciably migrate into the interstitium, leading to a 56% increase in MR signal at

203 The accumulation of collagen within the lung interstitium leads to impaired respiratory function.

204 ephron cells but can switch fates into renal interstitium-like cell types.

205 mulation of fluid and cysts in the medullary interstitium, loss of medullary vascular bundles, and de

206 eposition of Fg in subendothelial matrix and interstitium making the immobilized Fg a readily accessi

207 Refocusing on the interstitium may potentially improve care through the id

208 ption of water into the hypertonic medullary interstitium mediated by collecting ducts.

209 estis cords (epithelium) and the surrounding interstitium (mesenchyme).

210 the seminiferous tubules and the testicular interstitium of busulfan-treated wild-type or c-kit muta

211 macrophages in the alveolar spaces and lung interstitium of COPD patients and controls.

212 ific T cell responses in the airway and lung interstitium of genetic B cell-deficient (Jh(-/-) knocko

213 hat the overexpression and deposition in the interstitium of high-molecular-weight hyaluronan (HA) is

214 mM to 10 mM, a level observed in the muscle interstitium of humans during exercise.

215 l mice, neutrophils remained confined in the interstitium of injured lungs and did not advance into t

216 nkeys were concentrated in the glomeruli and interstitium of kidneys, and in the portal triads and pa

217 Both glomeruli and interstitium of patients with SVV strongly expressed CD1

218 sion in vessels, respiratory epithelium, and interstitium of phosphatase-deficient lung.

219 crogram/kg per h) was infused into the renal interstitium of rats fed a normal phosphate diet (0.7% p

220 , GFP-positive donor cells were found in the interstitium of recipient testes, and they expressed the

221 ery of drug molecules of similar size to the interstitium of solid tumors.

222 ence of continuous remodeling in the cardiac interstitium of the hibernating myocardium, an important

223 l fibrosis, myofibroblasts accumulate in the interstitium of the kidney, leading to massive depositio

224 lenge reduced the collagen deposition in the interstitium of the lung that usually follows challenge.

225 The exit of lymphocytes from the interstitium of the lung, across the bronchial epitheliu

226 to four times more likely to migrate to the interstitium of the myocardium than AdlacZ-infected epic

227 Mamu-AG stained few cells, primarily in the interstitium of the testis, there was consistent immunos

228 r survival of fetal Leydig precursors in the interstitium of the XY gonad.

229 of administered fluid accumulate in the lung interstitium of these patients.

230 WF+, alpha-SMA+ cells and were found in the "interstitium" of the scaffold.

231 arriers, drawing particular attention to the interstitium operating as a dynamic interface for water

232 R, uric acid was associated with doubling of interstitium or ESRD from IF/TA (OR 1.83, 95% CI, 1.06-3

233 the primary composite outcome of doubling of interstitium or ESRD from interstitial fibrosis and tubu

234 ran-retaining cells did not migrate into the interstitium or express alpha-smooth muscle actin.

235 and (5) numbers of monocytes/macrophages in interstitium or glomeruli, and (6) arterial proliferatio

236 ver, little is known about the origin of the interstitium or the molecular and cellular diversity wit

237 is involved in tau clearance from the brain interstitium, our results suggest that regional disrupti

238 creased, while fractional volume of cortical interstitium (P <0.00001) and atrophic tubules (P <0.01)

239 a-catenin from the underlying Wnt-responsive interstitium phenocopies the medullary deficiency of Wnt

240 ted to multiple cell types within the muscle interstitium, primarily endothelial cells.

241 deposition of type I collagen in the cardiac interstitium provides a noninvasive way to quantify myoc

242 lung development, leading to thickened lung interstitium, reduced airway branching, and perinatal de

243 was that mast cells within the inflammatory interstitium release chymase, an enzyme capable of effic

244 proliferation and resulting expansion of the interstitium remain largely unknown.

245 logy, particularly in the distal airways and interstitium, remains poorly described.

246 t from the IMCD lumen to the inner medullary interstitium, resulting in osmotic diuresis.

247 rolonged accumulation of eosinophils in lung interstitium results in prolonged, heightened airway hyp

248 Morphometric analysis of renal tubules and interstitium revealed a marked attenuation of tubular in

249 d by tumor cells and secreted into the tumor interstitium (secreted protein acid rich in cysteine).

250 The skin interstitium sequesters excess Na+ and Cl- in salt-sensi

251 ematopoietic origin within the infected lung interstitium serve as antigen presenting cells (APC) for

252 Reuptake of neurotransmitters from the brain interstitium shapes chemical signaling processes and is

253 of tumor vessels, oncotic pressure in tumor interstitium should be close to that in plasma.

254 thin or administered directly into the tumor interstitium, such as cytokines, chemokines, proteases,

255 s in transport properties of the vessels and interstitium that are associated with antiangiogenic the

256 dle-shaped cells were seen in the testicular interstitium that differed from the precursor cells in t

257 tropism to the basement membrane (BM)-renal interstitium that enables the bacteria to cause chronic

258 ts prime biologic importance for the cardiac interstitium that may rank highly in the hierarchy of va

259 haracterized cell types differentiate in the interstitium (the space between testis cords).

260 and 50% urea (to simulate in vivo papillary interstitium), the collected fluid osmolality was decrea

261 Many animals permanently inhabit the marine interstitium, the space between sand grains [1, 2].

262 of Henle and spreads from there through the interstitium to beneath the urothelium.

263 fibroblast population, relays signals to the interstitium to promote myofibroblast differentiation an

264 use protein and fluid extravasation into the interstitium to reduce the vascular volume.

265 articles tested to be delivered to the tumor interstitium to some degree.

266 ary plasma through the endothelial cells and interstitium to the cardiomyocyte, applying standard phy

267 re that serves to retrieve components of the interstitium to the lymph system.

268 ellular backflux of lanthanum from the renal interstitium to the proximal tubule lumen in association

269 ely), and the delivery of adenosine into the interstitium (to 290+/-80 and 299+/-143 nmol/L for the l

270 ased RIHP by 37% (Delta1.8 +/- 0.2 mmHg) and interstitium-to-lumen La backflux by 32% (Delta40.2 +/-

271 The net paracellular interstitium-to-lumen lanthanum backflux was measured be

272 rity of urinary ammonium; it is driven by an interstitium-to-lumen NH3 gradient due to the accumulati

273 blasts to express and secrete Loxl2 into the interstitium, triggering fibrosis, systolic and diastoli

274 utral macromolecules that equilibrate in the interstitium under various degrees of hydration.

275 mic changes in the metabolic profiles of the interstitium, urinary lumen, and glomerulus-areas that a

276 nce of tubular damage that exposes the renal interstitium, uromodulin becomes an endogenous danger si

277 vity was directly measured in the myocardial interstitium using a validated inline digital fluorogeni

278 um (La), was infused directly into the renal interstitium via a chronically implanted matrix.

279 rculating immune complexes "pumped" into the interstitium via trans-endothelial transport and trigger

280 on of ACE inhibitors directly into the renal interstitium, via the microdialysis probe, either did no

281 and the mean cleft path length from lumen to interstitium was 411 nm.

282 opically xenografted into the intrapulmonary interstitium was examined.

283 imilarly, staining of islets and parenchymal interstitium was not statistically associated with AMR.

284 tion in the capillary endothelium and neural interstitium was observed only in the contrast group.

285 sis of the medullary vasa recta and cortical interstitium was seen, but glomeruli were unaffected.

286 ge trace pericyte-like cells in the alveolar interstitium, we show that this population proliferates

287 Invading cells in the lung interstitium were also quantified after immunohistochemi

288 ercise, metabolites accumulate in the muscle interstitium where they stimulate chemosensitive afferen

289 ively charged glycosaminoglycans in the skin interstitium, where sodium is bound to glycosaminoglycan

290 l Wnt signaling in the surrounding medullary interstitium, where the capillaries reside.

291 cts to dilated proximal tubules and expanded interstitium, whereas active caspase-3 was mainly scatte

292 (int) macrophages are located throughout the interstitium, whereas F4/80(lo)/CD11c(hi) dendritic cell

293 ormation, and transported these ICs into the interstitium, whereas neutrophil depletion drastically r

294 ation was a T cell infiltration in the renal interstitium, which affected some tubules.

295 ts with acute AAV had more mast cells in the interstitium, which correlated with the severity of tubu

296 of NF-kappaB-positive nuclei to cells in the interstitium, which stained positive for the pericyte ma

297 he brain, suggesting that reaching the brain interstitium will be sufficient to ensure therapeutic ef

298 the atrial endothelium, penetrating into the interstitium, with increased collagen deposition.

299 MP appears in the pericapillary interstitium within 30 s of initiation of its intravenou

300 Although neutrophils locomote through the interstitium without pericellular collagen degradation,