ライフサイエンスコーパス: intestinal organoid

1 heroids were pre-organoids that matured into intestinal organoids.

2 ath in the intestinal epithelium of mice and intestinal organoids.

3 r stem cells (CSCs) and attenuated growth of intestinal organoids.

4 the more promiscuous transformation of small intestinal organoids.

5 ablishing a robust protocol for high quality intestinal organoids.

6 t to promote maintenance of Lgr5(+) IESCs in intestinal organoids, an effect mainly mediated by Greml

7 regulates differentiation of goblet cells in intestinal organoid and enterocyte cell cultures; differ

8 Remarkably, inhibition of MAPK signaling in intestinal organoids and cultured cells changed the rela

9 suppression of cell proliferation in murine intestinal organoids and human CRC lines.

10 We characterized the role of ATP7B in mouse intestinal organoids and tissues.

11 induced human pluripotent stem cell-derived intestinal organoids, and confirm in vivo that GH suppre

12 ly relevant targets of HECT E3s in cells and intestinal organoids, and in a genetic screen that ident

13 rom inducible pluripotent stem cells (termed intestinal organoids) are being applied to study human i

14 rk states, and vulnerabilities of transgenic intestinal organoids as a novel approach to understandin

15 n this issue of Cell Stem Cell, using murine intestinal organoids, Basak et al. (2017) induce stem ce

16 nzazepine increased the number of L cells in intestinal organoid-based mouse and human culture system

17 d new cultures can be induced to form mature intestinal organoids by exposure to Wnt3a.

18 The resulting three-dimensional intestinal 'organoids' consisted of a polarized, columna

19 We used mouse and human ex vivo 3D intestinal organoid cultures and in vivo mouse models to

20 In studies of intestinal organoid cultures and mice with inducible del

21 We generated intestinal organoid cultures from a subset of samples an

22 Intestinal organoid cultures from patient biopsies displ

23 Depletion of RIPK1 in intestinal organoid cultures sensitized them to TNF-indu

24 Like a HFD, ex vivo treatment of intestinal organoid cultures with fatty acid constituent

25 Using intestinal organoid cultures, we found that, compared wi

26 fluid secretion in two complementary models: intestinal organoids derived from subjects with CF and a

27 For molecular studies, we used intestinal organoids derived from these mice.

28 YAMC cells, and mouse and human intestinal organoids, died rapidly in response to TNF.

29 Gastric and small intestinal organoids differentiated from human pluripote

30 We investigated intestinal organoid emergence, focusing on measurable pa

31 cell cycle and circadian clock in 3D murine intestinal organoids (enteroids).

32 Using intestinal organoids from a CF mouse model, we determine

33 Intestinal organoids from Atoh1 mutant mice did not grow

34 ical Wnt/beta-catenin signalling, and induce intestinal organoid growth in vitro and Lgr5(+) ISCs in

35 erentiation of PSCs into 3-dimensional human intestinal organoids (HIOs) in vitro.

36 Here, we generated human intestinal organoids (HIOs) produced in vitro from human

37 luripotent stem cell (PSC) technology, human intestinal organoids (HIOs) with remarkably similarity t

38 rate potential applications in imaging human intestinal organoids (HIOs), colon mucosa, and retina.

39 Here, we asked if human intestinal organoids (HIOs), which are derived from plur

40 ural crest cells (NCCs) and developing human intestinal organoids (HIOs).

41 Here we exploited intestinal "organoids" (iHOs) generated from human induc

42 t PrP(c) is required for proper formation of intestinal organoids, indicating that it contributes to

43 of human pluripotent stem-cell-derived human intestinal organoids is globally similar to the immature

44 Intestinal organoids lacking ATG16L1 reproduced this los

45 Intestinal organoids offer great promise for modeling in

46 To generate intestinal organoids, pluripotent stem cells are first d

47 gr5-positive stem cells, isolated from small intestinal organoids, require Cdx2 to maintain their int

48 Intestinal organoid studies confirmed that high CIN does

49 Based on a previously described intestinal organoid swelling model, we established a 3D-

50 shes their ability to form long-term growing intestinal organoids that differentiate into intestinal

51 ric neural crest cells into developing human intestinal organoids, thereby restoring ENS cell types a

52 sions using high-resolution imaging and used intestinal organoids to identify underlying mechanisms.

53 We used intestinal organoids to quantitatively study the potency

54 mvent this limitation by exploiting cultured intestinal organoids together with single-cell measureme

55 Biodegradable polymer scaffolds seeded with intestinal organoid units were implanted into syngenic r

56 degradable polymers seeded with neonatal rat intestinal organoid units were implanted into the omenta

57 Using human embryonic stem cell-derived intestinal organoids, we demonstrate that the duration o

58 Intestinal organoids were cultured on tissue matrices.

59 When intestinal organoids were stimulated with IL-4, tuft cel