ライフサイエンスコーパス: intestine

1 portant in the nervous system, germ line and intestine.

2 can influence the replication of CVB3 in the intestine.

3 pidly increase in both lymph nodes (LNs) and intestine.

4 h as the brain, the lung, the kidney, or the intestine.

5 delivery of nutrients to the proximal small intestine.

6 mary site of injury, namely the distal small intestine.

7 iting enteric virus replication in the human intestine.

8 ct anthocyanins were absorbed from the small intestine.

9 ontaining vesicles or Fe agglomerates in the intestine.

10 an IL-23-driven inflammatory response in the intestine.

11 on in skin, joints, and eyes, but not in the intestine.

12 frequencies are maintained in the blood and intestine.

13 ong the proximal-to-distal axis of the small intestine.

14 can be formed even at neutral pH, as in the intestine.

15 ion increases L. monocytogenes growth in the intestine.

16 meability and absorption marker drugs in the intestine.

17 ctional adaptations of the gills, kidney and intestine.

18 exerting its immunomodulatory effect on the intestine.

19 ing it is an effective radioprotector of the intestine.

20 nfect specific cell populations in the human intestine.

21 ose-induced GLP-1 secretion from human small intestine.

22 coxsackievirus to infect mice, bypassing the intestine.

23 necessary to more closely approximate normal intestine.

24 lesterol transporters, in the proximal small intestine.

25 gut wall form an oxygen gradient within the intestine.

26 of TR in the control and T3-treated tadpole intestine.

27 differentiate, or survive within the distal intestine.

28 icient C. jejuni colonization of the chicken intestine.

29 er age, but reduces clearance from the small intestine.

30 s that mediate the colonization of the human intestine.

31 led to increased retinoid production in the intestine.

32 e stable during 8h passage through the upper intestine.

33 gion-specific manner in the developing human intestine.

34 ntenance of protective PCs for life in human intestine.

35 and lacks many of the complexities of normal intestine.

36 and exacerbates chronic inflammation in the intestine.

37 influences development of the immature human intestine.

38 lphaalpha intraepithelial lymphocytes in the intestine.

39 roximal-distal absorption gradient along the intestine.

40 E2), the most important COX-2 product in the intestine.

41 smooth muscle contraction in the bladder and intestine.

42 B regulates vesicular storage of Cu in mouse intestine.

43 ipid homeostasis in fat body/adipose and the intestine.

44 ies and chronic inflammatory diseases of the intestine.

45 tigate coxsackievirus replication within the intestine.

46 suggestive of a role for TM6SF2 in the small intestine.

47 ontrasted with what is known about the small intestine.

48 nificant reduction in loss of fluid into the intestine.

49 s its principal protein partner in the small intestine.

50 the segmentation motor pattern of the small intestine.

51 the aquatic environment and within the human intestine.

52 ion of the metabolizing enzyme, IDO1, in the intestine.

53 tine interaction, and huNoV infection in the intestine.

54 F-2alpha, and HIF-3alpha, are present in the intestine.

55 in looping morphogenesis of the avian small intestine.

56 ically in large lymphoid follicles along the intestine.

57 regulating the proliferative capacity of the intestine.

58 microbiota and SCFA production in the small intestines.

59 gene expression in the mouse small and large intestines.

60 helium and reduced bile re-absorption in the intestines.

61 treatments for melanoma metastasized to the intestines.

62 al barrier and secretomotor functions of the intestines.

63 ntenance of innate immune homeostasis in the intestines.

64 n repressing developmental maturation of the intestines.

65 und in the subepithelial region of the small intestine 24h after pollens were gavaged to mice.

66 ly digested food causes bloating, overfilled intestines, abdominal pain, excessive feces, steatorrhea

67 hymal cells are programmed to develop in the intestine after birth to constitute a specialized microe

68 conductance in epithelial cell cultures and intestine after cAMP agonists, cholera toxin, or heat-st

69 As a consequence, loss of SEDT2 in the intestine aggravated Wnt/beta-catenin signaling effects,

70 ging epithelial and mesenchymal cells in the intestine, airways, and skin and discuss how immune comm

71 ated that microcapsules released Lf in small intestine allowing 6.5 times higher concentration than i

72 Transport of fluid and electrolytes in the intestine allows for appropriate adjustments in luminal

73 The intestine also expresses ATP7B, but little is known abou

74 ntestinal samples were taken from 4 isolated intestine and 3 multivisceral transplant recipients at t

75 ecific knockout of the TMEM16A gene in mouse intestine and airways not only eliminates Ca(2+)-activat

76 imary cultures of enteroids from human small intestine and anion current in enteroid monolayers.

77 Survivin could be detected in the small intestine and ascending colon of the normoxia group.

78 s detected in the ischemically damaged small intestine and ascending colon.

79 mesenteric ischemia/reperfusion in the small intestine and by dextran sulfate sodium in the colon.

80 estinal epithelial cells (IECs) in the small intestine and colon is required for enteric IFN-lambda a

81 We used 3-dimensional small intestine and colon organoids, along with RNA-Seq and ge

82 membrane, damaging epithelial cells in small intestine and colon.

83 and their effects on inflammation within the intestine and distally at sites as anatomically remote a

84 al ileum to cause cholera, and the arthropod intestine and exoskeleton to persist in the aquatic envi

85 us system, heart, lung, skeletal muscle, and intestine and illustrate how macrophages might be exploi

86 evated trophozoite colonization in the small intestine and impaired weight gain.

87 affolds that mimic the 3-D topography of the intestine and its fluid flow.

88 ough is involved in clearance from the small intestine and longer-term clearance from the ceca.

89 t control fluid transport homeostasis in the intestine and might provide novel therapeutic avenues fo

90 cessibility during passage through the small intestine and modulated the formation of the degradation

91 3 individual epithelial cells from the small intestine and organoids of mice, which enabled the ident

92 ned in a catalytically inactive state in the intestine and other organs.

93 501-1 itself, destroyed the integrity of the intestine and pharynx.

94 ed atherogenic lipid metabolites in both the intestine and plasma via altered gut microbiota composit

95 ted with the number of infected cells in the intestine and plasma viral load.

96 :1) and lysophosphatidic acids (LPAs) in the intestine and plasma.

97 atial resolution of drug distribution in the intestine and provided experimental evidence for the sug

98 tensions, adapt to oxygen limitation in the intestine and resist host oxidative attack.

99 the ability to evaluate food quality in the intestine and respond to nutrient deficiencies with chan

100 stine HIF-2alpha inhibition markedly reduced intestine and serum ceramide levels.

101 owever, Th17 cells are present in the normal intestine and show a homeostatic phenotype; that is, the

102 infection, including both the proximal small intestine and the colon.

103 o NPs to be predominantly present within the intestine and the epithelium, and they were not colocali

104 he parental strain was observed in the small intestine and the liver.

105 one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator

106 ressed T effector cell migration between the intestine and the spleen in EAU Kaede mice.

107 merican Society of Transplantation Liver and Intestine and Thoracic and Critical Care Communities of

108 ient to create a reducing environment in the intestine and to partially modulate glucose metabolism.

109 , primary enterocytes were isolated from the intestine and transfected with the uc.173 transgene to i

110 ocyte surface in the mid-region of the small intestine and translocate through the epithelial cell mo

111 ncompass homeostasis and inflammation in the intestine and, in certain cases, extraintestinal tissues

112 express an FXR transgene specifically in the intestine, and ABCG8-knockout mice.

113 ased IL-1beta, IL-6, and IL-8 in fetal lung, intestine, and brain, and morphological abnormalities: e

114 on the function of MSI in the blood and the intestine, and discuss therapeutic strategies for target

115 troke volume, increasing fluid loss into the intestine, and increasing inflammatory cytokine producti

116 pleen, liver, kidneys, stomach, colon, small intestine, and pancreas, respectively.

117 ressor in the mouse colon, but not the small intestine, and that invasive ARID1A-deficient adenocarci

118 17 T cell generation and accumulation in the intestine, and the disease severity.

119 region-specific gene expression in the adult intestine are known, but how intestinal regional identit

120 subpopulations that induce Th2 cells in the intestine are unidentified.

121 different dendritic cell (DC) subsets in the intestine are yet to be defined.

122 tly precise turnover of the adult Drosophila intestine arises through a coupling mechanism in which e

123 can result in non-specific permeation of the intestine as well as enhancer overdosing in some areas d

124 pulations expressing CD155 in the tonsil and intestine, as well as in spinal cord neurons.

125 on, and migration in mucosal tissues (lungs, intestines), associated lymph nodes (LNs), and other lym

126 vels of EVI and MDS/EVI are expressed in the intestine at the climax of metamorphosis and are induced

127 ering work has made a new model of the human intestine available and has begun making contributions t

128 Human-intestine biopsies from individuals with or without obes

129 specific niches colonized by these bacteria (intestine, blood, or the intracellular environment, for

130 elated decline in autophagic activity in the intestine, body-wall muscle, pharynx, and neurons of wil

131 g, airways, lamina propria (LP) of the small intestine, brain, visceral adipose tissue, bone marrow (

132 st relative, GLUT7, is also expressed in the intestine but does not transport fructose.

133 y IgM(+) B cells disseminated throughout the intestine but rare in systemic lymphoid organs.

134 ls did not reduce survival of neurons in the intestine, but altered gastrointestinal motility in fema

135 des a noninvasive option to assess the small intestine, but its use with respect to endoscopic proced

136 an in vitro digestion model (mouth, stomach, intestine, but not colonic digestion).

137 patocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specifica

138 inated enteric glia from the small and large intestines, but caused no defects in epithelial prolifer

139 y, we studied PC dynamics in the human small intestine by cell-turnover analysis in organ transplants

140 yrate, produced by fermentation in the large intestine by gut microbiota, and its synthetic derivativ

141 iome, while age is a driving force for small intestine cancer.

142 red that Giardia's colonization of the small intestine causes a systemic dysbiosis of aerobic and ana

143 mordial germ cell-like cells and E18.5 small intestine, combined with functional annotation analysis

144 expression of interferon gamma in the small intestine compared to wild-type mice exposed to smoke.

145 Mesenchymal cells in the intestine comprise a variety of cell types of diverse or

146 sociated microbiota, between small and large intestine, concordant with differences in regional oxyge

147 The small intestine contains CD4(+)CD8alphaalpha(+) double-positiv

148 ive macrophages in the lymph nodes (LNs) and intestine corresponded with an increasing number of macr

149 Misbalance of Cu and lipid in the intestine could account for gastrointestinal manifestati

150 Transplantable vascularized bioengineered intestine could restore nutrient absorption.

151 In the adult intestine, crypt fission is observed at a low frequency.

152 7b(-/-) mice had reduced Cu storage pools in intestine, Cu depletion, accumulation of triglyceride-fi

153 Analysis of ileal effluents (at end of small intestine) demonstrated that 30% of ingested anthocyanin

154 We also show that small intestine dendritic cells from pregnant, but not from no

155 trast, exaggerated expression of mst reduced intestine diameters, but increased intestinal motilities

156 l GI syndrome, focal (5 mm) radiation of the intestine did not cause any weight loss or lethality.

157 nt PKC-2 activation or inhibition in AFD (or intestine) disclosed that PKC-2 regulates initiation and

158 of miR-263a, the intraluminal surface of the intestine displays dehydration-like phenotypes, Na(+) le

159 The major iron transporters in the small intestine divalent metal-ion transporter 1 (DMT1) and fe

160 n of this key cytokine by ILC3s in the small intestine during development and under basal conditions.

161 terotoxin and beta toxin are produced in the intestines during human and animal disease, these findin

162 nt delivery to the proximal and distal small intestine elicits different outcomes.

163 r to TBI was increased crypt loss within the intestine epithelium.

164 lls and established conditions to grow "mini-intestines" ex vivo in differentiated and undifferentiat

165 utant mice the Wnt signature was lost, these intestines exhibited ubiquitous epithelial presence of n

166 f polyphenols after in vitro simulated large intestine fermentation was carried out on edible nuts.

167 xpression regionally along the length of the intestine from fish to mammals and identified a core set

168 solated from the lamina propria of the large intestine from wild type or CerS6-deficient groups showe

169 ings show that the early postnatal mammalian intestine functions as an environmental sensor of nutrit

170 the OA patients, more AYA patients had small-intestine GISTs (139 [35.5%] vs 1465 [27.3%], P = .008)

171 The human intestine harbors a dense microbial ecosystem (microbiot

172 n humans, impaired regulation of H2O2 in the intestine has been associated with early-onset inflammat

173 The impact of acrolein on the intestine has not been investigated before and is evalua

174 d metabolism, with individual regions of the intestine having distinct functional roles.

175 ch is widely expressed in the body, e.g., in intestine, heart, and brain.

176 Host factors in the intestine help select for bacteria that promote health.

177 Intestine HIF-2alpha inhibition markedly reduced intesti

178 Mechanistically, intestine HIF-2alpha regulates ceramide metabolism mainl

179 n metabolic disorders that were dependent on intestine HIF-2alpha.

180 In human intestine, HMGA1 and SOX9 are positively correlated, and

181 the early adaptive phase and the role of the intestine, however, remain ill defined.

182 While expression of rde-4(+) in intestine, hypodermis, or neurons using a repetitive tra

183 IOs) with remarkably similarity to the fetal intestine in cellular composition, architecture, and abs

184 nsporters but does not support a role of the intestine in stimulating renal clearance of Pi.

185 BACKGROUND & AIMS: The role of the intestine in the maintenance of cholesterol homeostasis

186 rp9b or other inflammasome components in the intestine in vivo resulted in enhanced susceptibility of

187 Because the intestine includes a diverse array of cell types, howeve

188 to study intestinal glycan expression, huNoV-intestine interaction, and huNoV infection in the intest

189 Barrier dysfunction in the intestine is a common characteristic of aging organisms.

190 The intestine is a frequent site of metastases in melanoma p

191 However, the intestine is able to maintain the regenerative capacity

192 The mammalian intestine is colonized by trillions of bacteria that per

193 ry that GLP-2 promotes mucosal growth in the intestine is described, and key findings from both precl

194 Asymmetric rotation of the intestine is directed by forces outside the gut, but the

195 f obesity-associated insulin resistance, the intestine is emerging as a new site for immunologic chan

196 The ability to colonize the small intestine is essential for enterotoxigenic Escherichia c

197 udy suggests that drug exposure in the large intestine is essential for generating a superior in vivo

198 ls (FDC) in the Peyer's patches in the small intestine is essential for the efficient spread of disea

199 te here that the attachment of spores to the intestine is essential in the development of CDI.

200 RBP4-retinol uptake in developing liver and intestine is necessary to provide sufficient substrate f

201 The intestine is one of the organs most severely affected by

202 The human large intestine is populated by a high density of microorganis

203 s suggest that low-grade inflammation in the intestine is promoted by consumption of dietary emulsifi

204 Strikingly, ATP7A in the intestine is regulated in the opposite manner - low syst

205 wever adhesion and colonization to the human intestine is required for STEC pathogenesis.

206 unity assembly in the Caenorhabditis elegans intestine is sufficient to produce strong interworm hete

207 E), characterized by loss of proteins in the intestine, is a devastating complication in patients wit

208 in particular CD11b-expressing DCs from the intestine, is sufficient to prime S. mansoni-specific Th

209 In the intestine, it increased the expression of retinoic acid-

210 increases the abundance of E. rectale in the intestine, likely because it successfully captures the p

211 exhibit analogous effects on both liver and intestine lipid homeostasis.

212 lating levels of metabolites flowing through intestine, liver, and kidney.

213 erial metabolite concentrations in the large intestine luminal content, notably after changes in the

214 Barrier tissues, such as the intestine, lung, skin and liver, are exposed constantly

215 lymphocytes, dominant T cell subsets in the intestine, mediate both regulatory and pathogenic roles,

216 6SF2 deficiency resulted in defects in small intestine metabolism in response to dietary lipids, incl

217 questions on the impact of HPDs on the large intestine mucosa homeostasis.

218 osition and metabolic activity and for large intestine mucosal homeostasis.

219 ved an enlarged Th17 population in the small intestine of C57BL/6.IgA(-/-) mice compared with wild-ty

220 segmented filamentous bacteria in the small intestine of IgA(-/-) mice.

221 nsepithelial resistance, is increased in the intestine of mice with global deletion of Lpar1, Lpar1(-

222 genitors from tunica muscularis of the small intestine of newborn (postnatal day 0) wild-type C57BL/6

223 ssociated microbiota along the length of the intestine of piglets, and determined the effect of SUCRA

224 By using the intestine of premetamorphic tadpoles treated with or wit

225 colonization and proliferation in the small intestine of the host may, however, disrupt the ecologic

226 Intestines of Atp7b(-/-) mice had reduced Cu storage poo

227 iously identified enteroadherent EPEC in the intestines of deceased kittens.

228 Crude extract was obtained from intestines of fish Nile tilapia (Oreochromis niloticus)

229 e expression and histamine production in the intestines of Hdc(-/-) mice.

230 ntestinal epithelial cells (IECs) and in the intestines of mice, and studied the mechanisms of these

231 sistance against VRE and clears VRE from the intestines of mice.

232 We investigated the importance of the large intestine on the bioavailability of anthocyanins from bi

233 Bioengineering intestine on vascularized native scaffolds could bridge

234 intraoperative enterotomy, suture repair of intestine, or bowel resection.

235 Mucosal sites such as the intestine, oral cavity, nasopharynx, and vagina all have

236 cavity, esophagus, stomach, small and large intestines, pancreas, and liver.

237 siding in adipose tissues, as well as in the intestine, participate in this process.

238 ns between the enteric microbiota and distal intestine play important roles in regulating human healt

239 The intestine plays a central role in digestion, nutrient ab

240 s that promote IL-22 expression in the human intestine remain poorly understood.

241 of oral bacteria ectopically colonizing the intestine remains unclear.

242 ) and within the lamina propria of the small intestine, respectively (C.

243 CD4(+) T cell subsets in SLOs and the small intestine, respectively (C.

244 In nematodes, the intestine senses and integrates early life dietary cues

245 The fluids of the intestine serve as a physical barrier to pathogens, a me

246 ur distinct Mf subpopulations in human small intestine (SI).

247 w, spleen, lymph nodes), and mucosal (lungs, intestines) sites from a population of brain-dead organ

248 s expressed predominantly in liver and small intestine, sites for triglyceride-rich lipoprotein bioge

249 his correlation was verified in mice with an intestine-specific disruption of Hif2a, in which high-fa

250 We report here that the intestine-specific homeobox protein ISX is critical to c

251 Some mice with intestine-specific knockout of FXR were given daily inje

252 ith C57Bl/6J mice, as well as with mice with intestine-specific knockout of the farnesoid X receptor

253 ministration decreases ATP7A suggesting that intestine-specific non-autonomous regulation of ATP7A ab

254 er, skin-specific proteins Sbsn and Dmkn and intestine-specific proteins Dmbt1, Krt19, and Maoa, amon

255 with the observed dose dependence in cells, intestine-specific Sirt1 heterozygous mice have enhanced

256 enhanced intestinal tumor formation, whereas intestine-specific Sirt1 homozygous knockout mice have r

257 ells were reduced in the blood compared with intestine; T-cell responses that we detected had an incr

258 chloride/bicarbonate channel in airways and intestine that is activated through ATP binding and phos

259 The development of in vitro artificial small intestines that realistically mimic in vivo systems will

260 -apoptotic activity in mouse thymi and small intestines, the chromosomal instability caused by Atf3 d

261 ly significant site of Ret expression in the intestine: the intestinal epithelium.

262 ation of glucuronide-conjugated drugs in the intestine, thereby reducing drug toxicity.

263 ulation of electrogenic ion transport in the intestine through effects on neurons and possibly direct

264 ivation of caspase-3 could be tracked in the intestine through multiphoton laser scanning microscopy

265 have shown that CAMK2gamma protects against intestine tissue injury by increasing IEC survival and p

266 alters the metabolic environment of the host intestine to enhance bacterial pathogenicity.

267 delivery of nutrients into the distal small intestine to promote satiety and suppress food intake pr

268 rt bowel syndrome lack sufficient functional intestine to sustain themselves with enteral intake alon

269 s epithelial cells before spreading from the intestine to the cells of the liver and spleen.

270 stem cell-derived enteroids from human small intestines to study enterovirus infections of the intest

271 signaling molecules (e.g. gut microbiome-to-intestine-to-blood-to-liver-to-kidney-to-urine).

272 rase staining and embryonic day 12.5 (E12.5) intestine transcriptome by RNA-sequencing.

273 ng survival, presence of myenteric plexus or intestine transcriptome.

274 nteraction between the two genes influencing intestine transcriptome.

275 jection after liver transplantation (LTx) or intestine transplantation (ITx) in small cohorts of chil

276 sosome-like organelles (gut granules) in the intestine under copper overload conditions for copper de

277 al barrier and secretomotor functions of the intestines under physiological conditions is not clear.

278 ll patients for toxigenic C difficile in the intestine upon admittance, from October 1, 2012, to Janu

279 in maintenance of epithelial barrier in the intestine via regulation of apical junction integrity.

280 nt in the reference material would reach the intestine wall.

281 city in site-of-contact tissues (e.g., small intestine) was generally more than dose-additive and the

282 Next, focusing on the developing chick small intestine, we determined that Bmp2 expressed in the dors

283 goal of modeling human disease of the large intestine, we sought to develop an effective protocol fo

284 Recipients of all organs except intestine were included, and the follow-up periods were

285 infection, these concentrations in the large intestine were the sole predictors of the observed in vi

286 g/mouse for 3-6 hours) or vehicle (control); intestines were collected and analyzed by immunofluoresc

287 Intestines were collected and analyzed histologically an

288 Intestines were collected from mice and gene expression

289 macrophages in resolving inflammation in the intestine, where it helps protects against colitis-assoc

290 essed at the crypt base throughout the small intestine, where it is enriched in crypt base columnar s

291 103(+) DCs induce Th2 responses in the small intestine, whereas CD11b(+)CD103(-) DCs perform this rol

292 fection altered the metabolic profile of the intestine, which directly enhanced bacterial expression

293 ococcus) were found in the stomach and small intestine, while anaerobic Lachnospiraceae and Ruminococ

294 integration of inflammatory signals from the intestine with efferent neural inputs.

295 Mst expression was detected in the adult intestine with its prominent localization to actin filam

296 C. jejuni requirements to colonize the mouse intestine with those necessary to grow in different cult

297 ormal multicellular composition of the mouse intestine, with luminal flow to control perturbations (e

298 itting proper placement of the lengthy small intestine within the confines of the body cavity.

299 s immotile, thus they pass through the small intestine without colonizing.

300 tal in maintaining immune homeostasis in the intestine, yet studies on the origin and heterogeneity o