ライフサイエンスコーパス: intra-arterial

1 To date, ELIP delivery has been intra-arterial.

2 M110 (VisEn Medical, Woburn, Massachusetts), intra-arterial 2D NIRF imaging was performed in rabbit a

3 Endothelial function (response to intra-arterial acetylcholine) was assessed with forearm

4 preventable were treated with intravenous or intra-arterial acute stroke therapy while these treatmen

5 Direct excitation of a CB with intra-arterial adenosine increased VI, systolic BP, mean

6 control non-exercise vasodilator condition (intra-arterial adenosine infusion) in seven young (25 +/

7 ip circulatory arrest, and administration of intra-arterial adenosine were performed to clarify the m

8 control non-exercise vasodilator condition (intra-arterial adenosine), before and after local NO syn

9 control non-exercise vasodilator condition (intra-arterial adenosine).

10 Studies in human have been performed after intra-arterial administration of [123I]IUdR in patients

11 er saturation of P2 purinoceptors with acute intra-arterial administration of ATP (1 mg/kg per min).

12 isplayed a decreased pressor response to the intra-arterial administration of capsaicin within the hi

13 Acute intra-arterial administration of EGCG to mesenteric vasc

14 Intra-arterial administration of lactic acid (to simulat

15 In protocol 1 (n = 12), subjects received intra-arterial administration of saline (control) and th

16 provement in forearm blood flow responses to intra-arterial administration of the endothelium-depende

17 iolabelled microspheres before and after the intra-arterial administration of the selective nNOS inhi

18 ther treatment options, such as systemic and intra-arterial administration of therapeutics ( 3 - 5 ).

19 Several interventions, including intra-arterial administration of thrombolytic agents and

20 ng this model, we tested the hypothesis that intra-arterial administration of TNK-tPA, a fibrin speci

21 d in a side branch of the femoral artery for intra-arterial administration of tyramine, an agent whic

22 Intra-arterial administration of vitamin C significantly

23 This was comparable to the effect after intra-arterial administration.

24 eived intravenous alteplase and six received intra-arterial alteplase.

25 avenous alteplase and 4.5 h (3.8-24.0 h) for intra-arterial alteplase.

26 f age who had undergone pretreatment 24-hour intra-arterial ambulatory blood pressure monitoring on t

27 Patients (n=479) who underwent 24-hour intra-arterial ambulatory blood pressure monitoring on t

28 AP and ICP were monitored continuously using intra-arterial and cisterna magna catheters, respectivel

29 These data demonstrate that adjuvant intra-arterial and intravenous chemotherapy was benefici

30 ed our attention on more "protected" routes: intra-arterial and intravesicular administration.

31 chemoreduction with consolidation as well as intra-arterial and intravitreal chemotherapies.

32 g different effector populations and between intra-arterial and systemic injections.

33 by administration of acetazolamide (oral or intra-arterial) and oral raloxifene (P=0.0248, P<0.0001,

34 imaging, now widely available, is replacing intra-arterial angiography for carotid stenosis, but the

35 curacy of non-invasive imaging compared with intra-arterial angiography for diagnosing carotid stenos

36 studies comparing non-invasive imaging with intra-arterial angiography that met Standards for Report

37 Intra-arterial AO infusion was effective in these models

38 Changes in LN and CT activity following intra-arterial application of P2X agonists were compared

39 Intra-arterial application of TTX and L-NAME did not cau

40 Vasodilator responses (%FVC) during intra-arterial ATP infusions were unchanged following co

41 ffects on nitric oxide release caused by the intra-arterial ATP infusions.

42 e assessed the safety and efficacy of adding intra-arterial autologous adipose-derived MSCs into STK

43 safety, tolerability and pharmacokinetics of intra-arterial basic fibroblast growth factor (bFGF) in

44 Intra-arterial bFGF was safe and well-tolerated.

45 n 16 COI patients and 16 healthy volunteers, intra-arterial blood pressure (BP), ECG, central venous

46 noninvasive blood pressure measurement with intra-arterial blood pressure measurement in critically

47 or managing other critical illnesses suggest intra-arterial blood pressure measurement is preferred o

48 our institution and others in preference to intra-arterial blood pressure measurement remained preva

49 ed via venous occlusion plethysmography) and intra-arterial blood pressure to quantify local vasodila

50 Oxygen saturation, intra-arterial blood pressure, central venous pressure,

51 n dioxide (ETCO2), oxygen saturation (SaO2), intra-arterial blood pressure, electrocardiography (EKG)

52 jects by an alternate CEU technique using an intra-arterial bolus injection of albumin microbubbles a

53 lower tonic ANS support of BP (reduction in intra-arterial BP during acute ganglionic blockade [GB]

54 All infusions were intra-arterial (brachial).

55 We measured the effects of intra-arterial bradykinin (100, 200, and 400 ng/min), ac

56 ntration gradient and forearm plasma flow to intra-arterial bradykinin and sodium nitroprusside.

57 vasive tests, used cautiously, could replace intra-arterial carotid angiography for 70-99% stenosis.

58 Here we report a dual-modality intra-arterial catheter for simultaneous microstructural

59 automated oscillometric devices pending the intra-arterial catheter insertion or after its removal.

60 on, end-tidal CO2 (PET,CO2), blood pressure (intra-arterial catheter or photoelectric plethysmograph)

61 drug carriers should be ideal for selective intra-arterial catheter-directed administration to liver

62 ore (p < .05) invasive monitoring, including intra-arterial catheters and central venous pressure cat

63 ollowing intravenous chemotherapy (n = 6) or intra-arterial chemotherapy (n = 5).

64 Concomitant intra-arterial chemotherapy (P = 0.01) and greater inher

65 6 cycles of intravenous chemotherapy and/or intra-arterial chemotherapy and subsequently developed r

66 Both intravenous and intra-arterial chemotherapy are powerful methods for ret

67 tudies are available, it is recommended that intra-arterial chemotherapy be offered selectively among

68 Importance: Intra-arterial chemotherapy has emerged as a treatment f

69 Intra-arterial chemotherapy involves single-agent inject

70 Conclusions and Relevance: Intra-arterial chemotherapy is a promising new treatment

71 Intra-arterial chemotherapy is used as primary therapy i

72 Intra-arterial chemotherapy provides excellent tumor con

73 In 2011, the era of intra-arterial chemotherapy was announced with several s

74 we face the recently popularized modality of intra-arterial chemotherapy with caution and hope.

75 After two cycles of intra-arterial chemotherapy with melphalan, the main tum

76 d; and plaque brachytherapy, chemoreduction, intra-arterial chemotherapy, and intraocular injections

77 As with eyes treated with intra-arterial chemotherapy, seed classification is pred

78 enucleation, intravenous chemoreduction, and intra-arterial chemotherapy.

79 patients treated predominantly with primary intra-arterial chemotherapy.

80 alysis to summarize the reported outcomes of intra-arterial chemotherapy.

81 ransplantation, and newer modalities such as intra-arterial chemotherapy.

82 ve endothelial cells is indeed essential for intra-arterial cluster, haematopoietic progenitor and HS

83 r endothelial cells through the formation of intra-arterial clusters and that Runx1 functions during

84 Intra-arterial co-administration of lactic acid and E-2

85 Vascular OS was assessed by intra-arterial co-infusion of vitamin C and acetylcholin

86 Intra-arterial cyclo(Gly-Gln) (5 mg/kg) and i.c.v. Gly-G

87 asminogen activators by both intravenous and intra-arterial delivery have highlighted limitations to

88 Intra-arterial delivery of antibody against TSP1 facilit

89 Intra-arterial delivery of chemotherapeutic agents offer

90 and intracranial stenosis, as well as local intra-arterial delivery of thrombolytic agents in patien

91 orter gene-labeled MAPCs are maximized after intra-arterial delivery or host irradiation and that T c

92 potentially sufficient for diapedesis after intra-arterial delivery.

93 Intra-arterial digital subtraction angiography did not i

94 Although intra-arterial digital subtraction angiography remains t

95 (TCD) have been advocated as alternatives to intra-arterial digital subtraction angiography to screen

96 istently superior results when compared with intra-arterial digital subtraction angiography.

97 flow in the ischemic limb was determined by intra-arterial Doppler flow measurements and microsphere

98 giographic score, calf blood pressure ratio, intra-arterial Doppler flow, and microsphere distributio

99 flow in the ischemic limb (measured with an intra-arterial Doppler wire) at rest (phVEGF165 = 21.3 +

100 Intra-arterial doppler-flow studies showed increased res

101 local effect, we evaluated the effect of an intra-arterial dose on forearm blood flow (FBF), while m

102 We measured the effect of intra-arterial enalaprilat (5 micro g/min) on forearm bl

103 were evaluated during wide-ranging doses of intra-arterial (femoral) infusions of PE and AngII at re

104 laboratory animals, but their usefulness for intra-arterial gene therapy may be limited by the preval

105 Preclinical findings suggest that intra-arterial gene transfer of a plasmid which encodes

106 K(ATP) activation was modulated by intra-arterial glibenclamide (blocker) and diazoxide (op

107 Moreover, these animals have greater intra-arterial hemorrhage, which might be due to less st

108 rgoing iatrogenic BBB disruption (BBBD) with intra-arterial hyperosmotic mannitol were compared with

109 llowing intracerebro-ventricular (i.c.v.) or intra-arterial (i.a.) administration to pentobarbital-an

110 ar effects on the increase in FVC induced by intra-arterial (I.A.) infusion of adenosine (at 1.2 mg k

111 Rats were made dependent following the intra-arterial (i.a.) infusion of increasing concentrati

112 Intra-arterial (i.a.) injection of a high dose of IL-1be

113 y subsequent to the demonstrated efficacy of intra-arterial (IA) device-based therapy in multiple tri

114 es of neural tissue in a single treatment is intra-arterial (IA) injection after osmotic blood brain

115 nts with PCNSL treated with osmotic BBBD and intra-arterial (IA) methotrexate at four institutions fr

116 ective: To report up-to-date outcome data of intra-arterial (IA) treatment in patients with BAO and t

117 peripheral blood flow in CHF patients after intra-arterial infusion and after oral administration in

118 ncept for CBL0137 and its administration via intra-arterial infusion as a superior treatment compared

119 titute CBL0137 in the ILP protocol, using an intra-arterial infusion method, to safely achieve effect

120 Intra-arterial infusion of 17 beta-oestradiol significan

121 local hyperglycemia (300 mg/dL) achieved by intra-arterial infusion of 50% dextrose.

122 responses (strain-gauge plethysmography) to intra-arterial infusion of a selective blocker of ETA re

123 studied the forearm blood flow responses to intra-arterial infusion of acetylcholine (7.5 to 30 micr

124 on plethysmography and blood sampling during intra-arterial infusion of acetylcholine, bradykinin, so

125 lusion plethysmography in response to serial intra-arterial infusion of acetylcholine, sodium nitropr

126 osine kinase inhibitor-as well as continuous intra-arterial infusion of adenosine.

127 ar conductance (CalfVC) were measured during intra-arterial infusion of an alpha-adrenoreceptor agoni

128 ence of clinical therapeutic angiogenesis by intra-arterial infusion of an angiogenic protein.

129 the nanomolar range and were not reduced by intra-arterial infusion of an angiotensin-converting enz

130 Repetitive intra-arterial infusion of autologous BMMNCs into the co

131 alation study provides evidence of safety of intra-arterial infusion of autologous MSCs in patients w

132 ned to repetitive (3 times; 3-week interval) intra-arterial infusion of BMMNC or placebo.

133 is trial was to determine whether repetitive intra-arterial infusion of bone marrow mononuclear cells

134 (FBF) and net t-PA release before and during intra-arterial infusion of bradykinin (25 to 400 ng/min)

135 These effects are abrogated by an intra-arterial infusion of corticosterone.

136 Intra-arterial infusion of ET-1 significantly increased

137 found in stroke animals that received local intra-arterial infusion of human PRP lysate (p's<0.05).

138 Forearm flow responses to intra-arterial infusion of increasing doses of acetylcho

139 was evaluated by measuring the effects of an intra-arterial infusion of incremental doses of carbacho

140 elium-dependent vasodilation was assessed by intra-arterial infusion of methacholine (0.3 to 10 micro

141 Using an intra-arterial infusion of N(G) -monomethyl-L -arginine

142 with and without NO synthase inhibition via intra-arterial infusion of N(G) -monomethyl-L -arginine

143 Intra-arterial infusion of N(G)-monomethyl-L-arginine (L

144 t nitric oxide synthase (NOS) inhibition via intra-arterial infusion of N(G)-monomethyl-L-arginine (L

145 ium-independent vasodilation was measured by intra-arterial infusion of nitroprusside (0.3 to 10 micr

146 The intra-arterial infusion of oncolytic adenoviruses warran

147 tra-arterial pressure via catheter) to local intra-arterial infusion of phenylephrine (PE; alpha1 -ad

148 ted changes in vascular conductance (FVC) to intra-arterial infusion of phenylephrine (PE; alpha1 -ag

149 Hindlimb intra-arterial infusion of pyridoxal phosphate-6-azophen

150 occlusion plethysmography before and during intra-arterial infusion of the arginase inhibitor N(omeg

151 resistance vessels (blood flow responses to intra-arterial infusion of the endothelium-dependent dil

152 hours after enalapril (20 mg) or placebo, an intra-arterial infusion of the NEP inhibitor thiorphan (

153 acologically enhanced with Mch or reduced by intra-arterial infusion of the nitric oxide inhibitor N(

154 y measuring the effects on venous tone of an intra-arterial infusion of the NO synthase inhibitor N-m

155 d, first before start of, and then during an intra-arterial infusion to, the muscle preparation of th

156 ar implantation appeared more effective than intra-arterial infusion, and mobilized peripheral blood

157 ycemia (300 mg/dL) created by dextrose (50%) intra-arterial infusion, and with coadministration of vi

158 oblastoma if administered locally via direct intra-arterial infusion.

159 man protein (rhVEGF-C; 500 microg) by direct intra-arterial infusion.

160 5.0 mg/kg) were administered as a 10-minute intra-arterial infusion; control animals received vehicl

161 ed by use of forearm blood flow responses to intra-arterial infusions of acetylcholine (a vasodilator

162 e above parameters were also assessed during intra-arterial infusions of acetylcholine and bradykinin

163 Agonist-induced vasodilation to incremental intra-arterial infusions of acetylcholine and bradykinin

164 Forearm venous occlusion plethysmography and intra-arterial infusions of acetylcholine and N(G)-monom

165 Forearm blood flow (FBF) responses to intra-arterial infusions of acetylcholine and sodium nit

166 Forearm blood flow (FBF) responses to intra-arterial infusions of acetylcholine, bradykinin, s

167 d 18 black control subjects before and after intra-arterial infusions of acetylcholine, nitroprusside

168 ascular conductance (FVC) responses to local intra-arterial infusions of ACh, ATP, and sodium nitropr

169 ation, and forearm blood flow in response to intra-arterial infusions of endothelial-dependent and -i

170 w (Q, ultrasound Doppler) at rest and during intra-arterial infusions of endothelium-dependent (acety

171 Forearm vascular responses to intra-arterial infusions of endothelium-dependent and -i

172 s occlusion plethysmography before and after intra-arterial infusions of N(G)-monomethyl-l-arginine (

173 otocols, measuring leg vascular responses to intra-arterial infusions of NG-monomethyl-l-arginine (l-

174 sures were also recorded in seven men during intra-arterial infusions of normal saline, phentolamine

175 alpha- and beta-adrenoreceptor blockade via intra-arterial infusions of phentolamine and propranolol

176 and calculated vascular conductance (FVC) to intra-arterial infusions of phenylephrine (alpha(1)-agon

177 ascular conductance (FVC) responses to local intra-arterial infusions of phenylephrine (alpha(1)-agon

178 sis were randomly assigned (1:1:1) bilateral intra-arterial infusions of placebo on days 1 and 30 (n=

179 Prior close-intra-arterial infusions of tetrodotoxin or hexamethoniu

180 in-gauge plethysmography) responses to local intra-arterial infusions of tyramine (which evokes endog

181 wth factor (rhVEGF) administered as a single intra-arterial injection (n=6), quinaprilat (n=8) or cap

182 SNA responses to contraction were reduced by intra-arterial injection into the hindlimb circulation o

183 Intra-arterial injection of 5-HT (20 microg kg-1) increa

184 we evaluated the cardiovascular responses to intra-arterial injection of AEA into the hindlimb of nor

185 ut had no effect on the pressor responses to intra-arterial injection of alpha,beta-methylene ATP or

186 ng to a compartment syndrome upon accidental intra-arterial injection of amiodarone in an emergency s

187 ic contraction, passive stretch and hindlimb intra-arterial injection of capsaicin in sham and CHF ra

188 re identified: group A neurones responded to intra-arterial injection of low doses of cholecystokinin

189 -anaesthetized recipient rats in response to intra-arterial injection of lymph close to the upper GI

190 radiation therapy (or radioembolization) by intra-arterial injection of radioactive yttrium-90-loade

191 Upon intra-arterial injection, a direct antithrombotic and va

192 jor uptake site after intravenous injection, intra-arterial injections were tested and found to resul

193 Intra-arterial insulin administration did not significan

194 led trials in which patients received either intra-arterial IOCM iodixanol (n = 1,382) or LOCM (n = 1

195 In contrast, none of the animals given intra-arterial islets showed even transient insulin inde

196 Intra-arterial L-NAME partially inhibited increases in U

197 ent between Marfan and control subjects, and intra-arterial L-NMMA produced similar reductions in bra

198 overy period, endotoxemia was initiated with intra-arterial lipopolysaccharide (1 mg/kg) in the prese

199 sside before and after the administration of intra-arterial losartan (10 mg).

200 went a set of three pairs of noninvasive and intra-arterial measurements at each site (arm, ankle, th

201 , to date, only intravenous thrombolysis and intra-arterial measures to restore perfusion have shown

202 Following intra-arterial mechanical injury, FGF2-deficient vessels

203 mbolysis (IVT) alone with IVT and adjunctive intra-arterial mechanical thrombectomy (MT) in patients

204 itreous seeds and the inadequate response to intra-arterial melphalan treatment, intravitreal melphal

205 ex vivo in aortic lesions with a customised intra-arterial NIRF detection catheter.

206 normal human subjects at baseline and after intra-arterial norepinephrine (1.2 micrograms) and nitro

207 h of treatment, vasoconstrictor responses to intra-arterial norepinephrine (NE) were compared in rest

208 FeCl(3) treatment resulted in intra-arterial occlusive thrombogenesis within 10 min in

209 Intra-arterial or automated cuff blood pressure and arte

210 Angioplasty and intra-arterial papaverine were used in patients with vas

211 200 microM) or PPADS (200 microM) applied by intra-arterial perfusion each antagonised the rapid incr

212 alpha,beta-meATP (100-300 microM, n = 14) by intra-arterial perfusion.

213 y for retinoblastoma, including intravenous, intra-arterial, periocular, and intravitreal techniques.

214 terial propranolol (IA PROP, 25 microg/min), intra-arterial phentolamine (IA PHEN, 12 microg/min per

215 vasculature as the final determinants of the intra-arterial pressure in hypertension.

216 nductance (FVC; Doppler ultrasound, brachial intra-arterial pressure via catheter) to local intra-art

217 nous phentolamine (IV PHEN, 500 microg/min), intra-arterial propranolol (IA PROP, 25 microg/min), int

218 atment options; long-term outcomes following intra-arterial radiation are unknown.

219 d postoperative therapies, including hepatic intra-arterial radiation, may improve the outlook for so

220 ombolysis, consisting of 7 intravenous and 5 intra-arterial recombinant tissue plasminogen activator

221 tion (assayed at the 2-day time point) by an intra-arterial replication-conditional HSV of tumor cell

222 We investigated whether one or two doses of intra-arterial rFGF-2 improves exercise capacity in pati

223 Intra-arterial rFGF-2 resulted in a significant increase

224 Intra-arterial route is very promising, but MSCs are mis

225 for retinoblastoma using intravenous versus intra-arterial route.

226 In protocol 2 (n = 10), subjects received intra-arterial saline (control) and combined L-NMMA-amin

227 A Paratrend 7 intra-arterial sensor was placed through either an 18- o

228 lic or pulmonary complications resulted from intra-arterial splenic hepatocyte infusion.

229 Expandable intra-arterial stents are widely used for treating coron

230 case of microemboli from the polymer coating intra-arterial stents starting months after placement an

231 Using intra-arterial streptozotocin infusion, we rendered four

232 One iliac artery was subjected to intra-arterial subablative infrared irradiation via a di

233 othelial Progenitor Cells via Transcutaneous Intra-arterial Supplementation (JUVENTAS) trial (NCT0037

234 othelial Progenitor Cells via Transcutaneous Intra-arterial Supplementation (JUVENTAS) trial is a ran

235 Studies comparing the efficacy of intra-arterial therapy (IAT) and medical therapy in redu

236 the relationship with treatment benefit from intra-arterial therapy (IAT).

237 mall number of studies were published on the intra-arterial therapy of stroke in the past year.

238 ree-phase study, 8 healthy subjects received intra-arterial thiorphan (30 nmol/min), the endothelin E

239 nts (blood pressure >160/100 mm Hg) received intra-arterial thiorphan (30 nmol/min).

240 onstrated strong positive data in support of intra-arterial thrombectomy procedures.

241 Intra-arterial thrombin infusion during ischemia signifi

242 odels of thrombotic stroke induced by either intra-arterial thrombin injection or ferric chloride app

243 ion of this receptor may also be relevant in intra-arterial thrombogenesis and myocardial ischemia-re

244 There is ongoing investigation of intra-arterial thrombolysis and of acute intra-arterial

245 HT regions after intra-arterial thrombolysis had lower permeability value

246 nous thrombolysis, but other methods such as intra-arterial thrombolysis or mechanical thrombectomy c

247 sue plasminogen activator or catheter-guided intra-arterial thrombolysis), the structural reorganizat

248 idging therapy of combining intravenous with intra-arterial thrombolysis, and trials of new thromboly

249 ients with acute ischemic stroke who receive intra-arterial thrombolysis.

250 of these data it has become evident that the intra-arterial thrombolytic therapy of acute ischemic st

251 The major development in the field of intra-arterial thrombolytic therapy over the past year w

252 e hemispheric cerebral ischemia treated with intra-arterial thrombolytic therapy within 6 hours of sy

253 of intra-arterial thrombolysis and of acute intra-arterial thrombus extraction for treatment of sele

254 significant diagnostic potential for imaging intra-arterial thrombus.

255 ator within 3 h of symptom onset followed by intra-arterial tissue plasminogen activator or EKOS ultr

256 lasminogen activator or EKOS ultrasound plus intra-arterial tissue plasminogen activator.

257 osphere platform was developed for selective intra-arterial transcatheter drug delivery to liver tumo

258 Intra-arterial treatment (IAT) for acute ischemic stroke

259 Acute intra-arterial treatment (IAT) in the setting of extracr

260 496 patients-232 (47%) in the intra-arterial treatment and usual care group and 264 (5

261 functional outcome according to the mRS for intra-arterial treatment and usual care than for usual c

262 hemicraniectomy, the differences between the intra-arterial treatment and usual care versus usual car

263 Exposures: Intra-arterial treatment by mechanical thrombectomy and/

264 Intra-arterial treatment did not cause a significant inc

265 We noted no significant difference in intra-arterial treatment effect between the ASPECTS subg

266 We estimated the intra-arterial treatment effect for all patients in MR C

267 Whether infarct size modifies intra-arterial treatment effect is not certain, particul

268 core (ASPECTS) on the safety and efficacy of intra-arterial treatment in a subgroup analysis of the M

269 ed, controlled, open-label, phase 3 trial of intra-arterial treatment in patients (aged >/=18 years f

270 Intra-arterial treatment may be at least as effective in

271 ature review on anesthetic considerations of intra-arterial treatment of acute ischemic stroke emphas

272 PURPOSE OF REVIEW: Efforts in intra-arterial treatment of acute ischemic stroke mainly

273 tients had recurrent ischaemic stroke in the intra-arterial treatment plus usual care group than in t

274 occlusion of the anterior circulation, given intra-arterial treatment within 6 h of stroke onset.

275 trast CT ASPECTS of more than 7 benefit from intra-arterial treatment, data from this study suggest t

276 FVC responses to intra-arterial tyramine (evokes endogenous noradrenaline

277 sponses to endogenous noradrenaline release (intra-arterial tyramine) were significantly blunted duri

278 In seven cases, intra-arterial urokinase was administered after the thro

279 entation of cardiac output, angioplasty, and intra-arterial vasodilators.

280 We determined the effects of acute intra-arterial vitamin C administration and chronic oral

281 d clinical outcomes of patients treated with intra-arterial yttrium-90 microspheres (Y90).