ライフサイエンスコーパス: intracellular distribution

1 microtubules are important in this enzyme's intracellular distribution.

2 w the molecule's cell surface expression and intracellular distribution.

3 expression, their pH sensitivity, and their intracellular distribution.

4 orylation status of GSK-3beta can affect its intracellular distribution.

5 e mechanism that mediates its activation and intracellular distribution.

6 cts of mutations in dynein regulators on its intracellular distribution.

7 dependent on intact actin polymers for their intracellular distribution.

8 pression of noncanonical Wnts modulates Rok2 intracellular distribution.

9 ylation of FAK, and a dramatic change in its intracellular distribution.

10 nctional status of eIF4E is regulated by its intracellular distribution.

11 for the absence of ERMES correlates with its intracellular distribution.

12 directly impacting both the GEF function and intracellular distribution.

13 G(q/11) signaling but are different in their intracellular distribution.

14 uorescent zinc(II) complexes to assess their intracellular distribution.

15 s the properties of these proteins and their intracellular distribution.

16 e Arp2/3 complex in cells by determining its intracellular distribution.

17 associated with enhanced efflux and altered intracellular distribution.

18 FGF-2 post-translational modification to its intracellular distribution.

19 both in terms of total number of signals and intracellular distribution.

20 s were absent, junctophilin 2 had sarcomeric intracellular distribution.

21 activation of PKGI with cGMP regulated SSG1 intracellular distribution.

22 ng in instantaneous release of Ce6 and rapid intracellular distribution.

23 primarily at the levels of transcription and intracellular distribution.

24 ociation with protein partners, and thus its intracellular distribution.

25 wavelength, allowing for the observation of intracellular distribution.

26 ne cells of the ovary, they display distinct intracellular distributions.

27 in COS7 and NIH3T3 cells exhibited distinct intracellular distributions.

28 phoinositides (PPIns) from the PM alters the intracellular distribution and activity of K- and H-Ras

29 ory cells and that BDNF(Met) could alter the intracellular distribution and activity-dependent secret

30 ted to conserve ATP and to ensure its proper intracellular distribution and coordination with other m

31 This manuscript describes the distinctive intracellular distribution and enzymatic activity of the

32 hannel alpha-subunit Kv4.3 and regulates its intracellular distribution and gating properties.

33 FREB has an intracellular distribution and lacks a canonical transme

34 Intracellular distribution and metabolic changes were ob

35 olecular masses but differed considerably in intracellular distribution and solubility.

36 To assess the intracellular distribution and stability of 125I-ODN del

37 ective ASGP-Rs showed normal ligand binding, intracellular distribution and trafficking patterns, and

38 to establish their characteristic asymmetric intracellular distributions and coordinate planar polari

39 te 95% amino acid sequence identity, similar intracellular distribution, and broad tissue distributio

40 teady-state levels, kinetics of degradation, intracellular distribution, and internalization rates.

41 nhanced tumor cell internalization, improved intracellular distribution, and potentiated anticancer a

42 CH 1 (March-I) regulates surface expression, intracellular distribution, and survival of pMHC-II in D

43 evels of specific cyclins and CDKs and their intracellular distribution, and the relative levels of m

44 of wild yeast differ biochemically, in their intracellular distributions, and in their ability to pro

45 displays an intriguing cell cycle-dependent intracellular distribution, apparently moving from the c

46 r compartments and that sterol transport and intracellular distribution are regulated by PIPs.

47 owever, the dynamics of MMP-9 production and intracellular distribution as well as the mechanisms res

48 actin polymerization, network formation, and intracellular distribution, as well as inhibits beta(2)

49 o total eNOS but did not change the relative intracellular distribution between these domains.

50 es resulted in similar expression levels and intracellular distribution, but AC6mut expression was as

51 ght form of a reporter K15P molecule and its intracellular distribution change when KSHV switches fro

52 ut the intensity of the signal increased and intracellular distribution changed dramatically in both

53 We investigated whether 27HC can change the intracellular distribution cholesterol and reduce hepati

54 The GTCTR chimera had a more predominant intracellular distribution compared to the TR.

55 sma membrane, whereas BCCa-I has a punctate, intracellular distribution consistent with a vesicular l

56 nding, increased cell death, and an abnormal intracellular distribution, consistent with protein dysf

57 ent study, we analyzed bFGF internalization, intracellular distribution, degradation, and stimulation

58 Reported structural, phenotypic, and intracellular distribution differences between the two C

59 igh levels in human cardiac myocytes with an intracellular distribution distinct from that of PDE3A a

60 In contrast, as expected from its intracellular distribution, endogenous or overexpressed

61 e constitutively active Rab5Q79L enhances m4 intracellular distribution, even in unstimulated cells.

62 GFP to Pex7p's COOH terminus shifts Pex7p's intracellular distribution from predominantly cytosolic

63 ration dependent manner marked by a shift in intracellular distribution from punctate spots to diffus

64 P1 (K38A and D231N) dramatically changed its intracellular distribution from punctate vesicular struc

65 se in myosin phosphorylation and a change in intracellular distribution in fibroblasts on fibrotic lu

66 We show here that GLUT8 has a novel intracellular distribution in hippocampal neurons and is

67 t the factors that regulate their uptake and intracellular distribution in living cells.

68 the function of syntaxin 13 we examined its intracellular distribution in nonpolarized cells.

69 cell-cell interactions, but their prominent intracellular distribution in vivo and different knock-o

70 ed on four viral proteins that have distinct intracellular distributions in infected cells, hemagglut

71 ng to cell type and have different roles and intracellular distributions in vivo.

72 f the time-dependence of cellular uptake and intracellular distribution, in evaluating and advancing

73 s localized to two cell types with differing intracellular distributions, insofar as staining was see

74 hibit cytotoxicity, and are characterized by intracellular distributions invariably dictated by their

75 revisiae, high affinity manganese uptake and intracellular distribution involve two members of the Nr

76 We also show that PML intracellular distribution is altered in NPM1-mutated AM

77 ence techniques indicate that this change in intracellular distribution is characterized by a shift o

78 results demonstrate that the dynamic Vangl2 intracellular distribution is coordinated with and neces

79 e, is quite similar in all fibers, but their intracellular distribution is fiber type-dependent.

80 associate with the plasma membrane, and its intracellular distribution is unaffected by mutations in

81 r understanding of cellular internalization, intracellular distribution mechanisms and interactions o

82 oes not alter beta-catenin protein levels or intracellular distribution nor does it induce an inhibit

83 As a demonstration, we show that the intracellular distribution of a fluorescein-labeled TFO

84 In this study we show for the first time the intracellular distribution of a K39 kinesin homologue in

85 Pb altered the levels, characteristics, and intracellular distribution of Abeta staining and amyloid

86 These findings suggest that intracellular distribution of activated TNF receptors ma

87 by confocal microscopy indicated a distinct intracellular distribution of Alexa-568-labeled GV-LDL a

88 In addition, the intracellular distribution of antioxidative enzymes may

89 he cis -acting sequence requirements and the intracellular distribution of APOBEC-1 in yeast were sim

90 Here, we have further investigated the intracellular distribution of AtELP.

91 nant clone expressing ipaH(7.8) restored the intracellular distribution of bacteria to that seen with

92 Both compounds altered the intracellular distribution of beta-catenin and GSK3beta

93 ding on regulation of PI3Kgamma activity and intracellular distribution of betaARs.

94 or dominant negative Rab mutants changed the intracellular distribution of capsids and affected the i

95 The intracellular distribution of CAS resembles that of tubu

96 The intracellular distribution of CbpA alters dramatically w

97 First, the intracellular distribution of CCS determines SOD1 partit

98 onfocal microscopy analyses revealed altered intracellular distribution of CD1d and LAMP-1 in LT-trea

99 differ with regard to how they influence the intracellular distribution of CD1d, its rate of internal

100 Here we show that Rad24 controls the intracellular distribution of Cdc25.

101 tigate the mechanisms of cellular uptake and intracellular distribution of cell-penetrating peptides.

102 vity is highly specific to Rev function: the intracellular distribution of cellular poly(A)(+) mRNA,

103 The intracellular distribution of CF3CO-adducts was studied

104 cells and in the mouse lung and altered the intracellular distribution of clathrin heavy chains.

105 The key role in the intracellular distribution of copper belongs to the rece

106 In the present study, the intracellular distribution of CPD was examined in AtT-20

107 pr and Vpx functions and also shows that the intracellular distribution of CUL4A and CUL4B can vary b

108 dings suggest that Roughex can influence the intracellular distribution of cyclin A and define Roughe

109 exit from mitosis, possibly by altering the intracellular distribution of cyclin B1.

110 orylation plays a key role in regulating the intracellular distribution of cyclins.

111 an examination of the quantity, quality and intracellular distribution of deltaAg and deltaRNA in se

112 rk that opens up new venues for the study of intracellular distribution of dinuclear transition metal

113 ous fractionation technique to determine the intracellular distribution of DMAPP in isoprene-emitting

114 The precise intracellular distribution of each of these proteins dep

115 proteins in COS-7 and CHO cells to study the intracellular distribution of ELOVL4 and to identify pos

116 A comparison was made with the intracellular distribution of endogenous cytochrome c ba

117 mic reticulum, had no apparent effect on the intracellular distribution of F13L-GFP, suggesting that

118 rtment, and observed a diurnal change in the intracellular distribution of Fabp7 mRNA in molecular la

119 Images of the intracellular distribution of FFP18 show that >65% is lo

120 We have characterized the intracellular distribution of fluorescently tagged phosp

121 ient to ensure efficient cellular uptake and intracellular distribution of fully unprotected peptides

122 The expression and intracellular distribution of G1-phase regulatory protei

123 onfocal analysis revealed markedly different intracellular distribution of GAPDH between nucleus and

124 The novel intracellular distribution of Gbeta(5).RGS protein compl

125 on of the Rho GAP domain of ExoS changed the intracellular distribution of GFP-Rac and GFP-Cdc42 from

126 Thus, the intracellular distribution of GSK-3 beta is dynamically

127 LANA was found to alter the intracellular distribution of GSK-3beta so that nuclear

128 s P-bodies (PBs) indicating that the dynamic intracellular distribution of hAgo2 in SGs, in PBs or at

129 We examined the intracellular distribution of Hendra virus F following e

130 Analysis of the intracellular distribution of incorporated iron revealed

131 Whereas EGF promoted a more uniform intracellular distribution of initially centrally locali

132 We have previously described the detailed intracellular distribution of inositol-1,4,5-trisphospha

133 ts of five NFL mutations on the assembly and intracellular distribution of intermediate filaments (IF

134 ed to enhance receptor binding and alter the intracellular distribution of internalized FGF-2.

135 ge iron metabolism, the uptake, release, and intracellular distribution of iron in the murine macroph

136 found that beta-arr2-/- neurons show altered intracellular distribution of JNK and cJun, and that mor

137 ant colocalization were also observed in the intracellular distribution of KIF5B and beta'-COP, a com

138 anding the mechanism underlying the distinct intracellular distribution of KSHV ORF45, we identified

139 Examination of the intracellular distribution of late viral mRNAs revealed,

140 Levels and intracellular distribution of Lyn, CD45, COOH-terminal S

141 cardiac fibroblasts, dramatically alters the intracellular distribution of M6P/IGF2R as well as that

142 d GFP as a molecular reporter to monitor the intracellular distribution of MBP-GFP fusion proteins in

143 tions at each of these positions altered the intracellular distribution of mCD1d and reduced its abil

144 vided the means for mapping the cellular and intracellular distribution of metallothionein, thus yiel

145 Thus, vasculature of the tissue and the intracellular distribution of mitochondria can play key

146 The proper intracellular distribution of mitochondria is assumed to

147 nin 2A may play a role in maintenance of the intracellular distribution of mitochondria.

148 transporters, NRAMP2, which functions in the intracellular distribution of Mn.

149 The VSV-M protein altered the intracellular distribution of murine CD1d molecules, res

150 or proper endosomal sorting, we analyzed the intracellular distribution of mutant forms of the recept

151 We propose that the intracellular distribution of Nim1 and Wee1 may serve to

152 These p7 mutations altered the intracellular distribution of NS2 and E2 and appeared to

153 this study was to establish the cellular and intracellular distribution of osteopontin in the rat kid

154 to the YGG(C/A)RRC sequence also altered the intracellular distribution of other endogenous tRNAs, su

155 The primarily intracellular distribution of PAI-2 also may indicate a

156 e ATP-binding pocket of PI(4)K, altering the intracellular distribution of phosphatidylinositol-4-pho

157 Thus, this study demonstrates that the intracellular distribution of PKD isoenzymes are distinc

158 chanisms associated with GPCR signaling, the intracellular distribution of PKD was analyzed in live c

159 ists (GPCR) on the regulatory properties and intracellular distribution of PKD3.

160 by the distinctive substrate specificity and intracellular distribution of PKDs.

161 o hours and, additionally, information about intracellular distribution of polyphosphate and heteroge

162 al but misplaced cell poles, we assessed the intracellular distribution of proteins that localize spe

163 Cellular uptake and intracellular distribution of PS ASOs are mediated by pr

164 revisiae is located in the mitochondria, the intracellular distribution of Q indicates the existence

165 Intracellular distribution of radioactivity revealed a t

166 er than 1 year of age, though changes in the intracellular distribution of red/green cone opsin were

167 The study of intracellular distribution of RGS3 indicated its unique

168 The intracellular distribution of Rh-CT(5-HT1A) resembles th

169 ization of replication complexes, reveal the intracellular distribution of RNA replication products,

170 The intracellular distribution of RNAs depends on interactio

171 triction at the point of division limits the intracellular distribution of RomR.

172 , we used confocal microscopy to examine the intracellular distribution of several RGS proteins in CO

173 oducing TGFbeta1 and the phosphorylation and intracellular distribution of SMAD2/3.

174 BoNT E expression altered the intracellular distribution of SNAP25, shifting it from a

175 k) is a ubiquitous enzyme functioning in the intracellular distribution of terminal phosphate bond en

176 esent a general response to cell stress, the intracellular distribution of the associated responses n

177 rin internalization and an alteration in the intracellular distribution of the cation-independent man

178 In this study, we examined the intracellular distribution of the chemoreceptors by immu

179 In this study, we examine the intracellular distribution of the cornified envelope pre

180 horbol esters, suggesting that change in the intracellular distribution of the enzyme is a mechanism

181 in normal skeletal muscle that regulates the intracellular distribution of the fatty acid transport p

182 Disease-associated mutations disrupt intracellular distribution of the FP/TMEM127 protein.

183 re characterized by discrete patterns of the intracellular distribution of the immunoreaction product

184 The intracellular distribution of the insulin-responsive ami

185 concentrations in membranes, to examine the intracellular distribution of the lipid within living ce

186 The intercellular and intracellular distribution of the movement protein (MP)

187 The role of MTs in the intracellular distribution of the MP also was analyzed b

188 The intracellular distribution of the NR2 subunits was strik

189 l of this study was to determine whether the intracellular distribution of the proapoptotic enzyme gl

190 Cleavage of MEKK1 at D68 changes the intracellular distribution of the protein from a Triton-

191 id also altered the detergent solubility and intracellular distribution of the protein when it was ex

192 P1 or PABP1-GFP resulted in heterogeneity of intracellular distribution of the protein.

193 The cellular uptake and intracellular distribution of the radioligands were char

194 play the predominant role in determining the intracellular distribution of the receptor.

195 evidence that the phosphorylation status and intracellular distribution of the RNA CUG-binding protei

196 Intracellular distribution of the SiNPs was evaluated wi

197 enin expression did not perturb the level or intracellular distribution of the tumor suppressor adeno

198 Thus, the intracellular distribution of the various ADAR1 isoforms

199 rity of both domains not only determines the intracellular distribution of the VEEV capsid but is als

200 Based on the intracellular distribution of the well established Abeta

201 In this study we investigated the intracellular distribution of the wild type (WT) and mut

202 ggesting that methylation is relevant to the intracellular distribution of these forms of FGF-2.

203 e expressed in skeletal muscle; however, the intracellular distribution of these hexokinase isoforms

204 Determination of the intracellular distribution of three previously uncharact

205 The involvement of MTs in the intracellular distribution of tobacco mosaic virus MP is

206 linked carbohydrates, and measurement of the intracellular distribution of TPO has often relied on th

207 h as angiotensin II and appears to alter the intracellular distribution of TRPC6 protein.

208 Expression, localization, and intracellular distribution of TRPP Ca(2+) channels were

209 oxygen species, and that cells can regulate intracellular distribution of YHb in accordance with thi

210 tive in the GEF activity of TRAPP II and the intracellular distribution of Ypt1 and Ypt31/32.

211 Neither did zinc deficiency affect the intracellular distribution of ZIP7 in mammalian cells.

212 , or after dissection from the lens, and the intracellular distributions of crystallins were examined

213 Intracellular distributions of filamentous actin (F-acti

214 oexpress VGF and SAAS peptides, and that the intracellular distributions of these peptides in arcuate

215 We also demonstrate that the intracellular distributions of ZnT6 as well as ZnT4 are

216 lective, because insulin does not affect the intracellular distribution or cell-surface localization

217 the actin filaments without inhibiting their intracellular distribution or the activity of the myosin

218 te with the human CD1b isoform, which has an intracellular distribution pattern similar to that of mu

219 ent in hippocampal projection neurons, their intracellular distribution patterns differ.

220 rmal folding and overall Slo1 and caveolin-1 intracellular distribution patterns.

221 s is necessary to achieve appropriate IGF-IR intracellular distribution point to the important role t

222 restingly, individual isoforms show distinct intracellular distributions: QKI-6 and QKI-7 are localiz

223 ic activity impacts on NAD(+) levels and its intracellular distribution remains unclear.

224 Identifying S100 intracellular distribution, site of action, and protein

225 fferent GPI-anchored proteins have different intracellular distributions; some (such as the folate re

226 in enterocytes maintains a homeostatic TLR9 intracellular distribution, supporting mucosal tolerance

227 Based on their copurification and intracellular distribution, vaults may be involved in th

228 reduced basicity were synthesized, and their intracellular distribution was evaluated.

229 Their intracellular distribution was similar to that of the en

230 81W mutant had an endoplasmic reticulum-like intracellular distribution, whereas L22V and wild-type A

231 adate inhibited the cell cycle dependency of intracellular distribution, while okadaic acid had littl

232 s, and a rho 1-GFP fusion gene showed mostly intracellular distribution with a faint fluorescence tow