ライフサイエンスコーパス: intracellular release

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1 til they are taken up into cells followed by intracellular release.

2 assively target antigen-presenting cells for intracellular release.

3 showed high extracellular stability and fast intracellular release.

4 ncapsulating a TLR8 agonist, allowing direct intracellular release after selective uptake by DCs.

5 ensory discharge, these results suggest that intracellular release and influx of Ca2+ occur during hy

6 and elevates [Ca(2+)](i) by first augmenting intracellular release and then the influx of extracellul

7 nts of 'drug retention in circulation versus intracellular release' and 'stealthy in circulation vers

8 ed [Ca(2+)](i) increase was not dependent on intracellular release from InsP(3)R or ryanodine recepto

9 are supported by LBPA, contribute to PS-ASO intracellular release from LEs.

10 the bound drugs in conditions mimicking the intracellular release media (10mM glutathione and pH 5.2

11 the pathogenesis of Alzheimer's disease, and intracellular release of a cytoplasmic tail fragment.

12 flow cytometry, we quantified the real-time intracellular release of a fluorescein at a single-cell

13 gnition of phosphoinositides and concomitant intracellular release of Ca(2+) is pivotal to almost eve

14 ; GE Healthcare, Princeton, NJ) and measured intracellular release of Ca(2+), calcineurin activation

15 ent of the calcium signalling network is the intracellular release of calcium in response to the prod

16 Intracellular release of cisplatin from 4 was further co

17 s suggested a bioreductive mechanism causing intracellular release of copper, which directly inhibite

18 e by cells, suggesting a mechanism involving intracellular release of DNA triggered by disulfide bond

19 ggesting a mechanism of action involving the intracellular release of FdUMP.

20 osis leads to disulfide linker reduction and intracellular release of free drug, but direct demonstra

21 ing intramolecular rearrangement, leading to intracellular release of functional mRNA and highly effi

22 is led to rapid loss of nuclear membrane and intracellular release of granule proteins with subsequen

23 cases, undergoes a cleavage resulting in the intracellular release of its C-terminal tail (CTT).

24 cles, there is very little data available on intracellular release of molecules encapsulated in membr

25 n the secondary site allosterically triggers intracellular release of Na(+) and substrate from the pr

26 tly decrease Na(+) affinity, indicating that intracellular release of Na(+) is facilitated.

27 pid conjugate internalization, and effective intracellular release of payload.

28 -site degradation of TH and facilitating the intracellular release of siRNA.

29 dyl nucleoside phosphoramidates involves the intracellular release of the active nucleotide following

30 haloethylamine nucleoside prodrugs involving intracellular release of the nucleotide.

31 conformational change enables translocation, intracellular release of the substrates, and reorientati

32 o modulate the NF-kappaB pathway through the intracellular release of the two bioactives.

33 they are disassembled by the low pH, causing intracellular release of their drug load.

34 switch that leads to the autoprocessing and intracellular release of toxin-effector domains.

35 n species, which were all dependent upon the intracellular release of zinc.

36 pyridine (DTDP), a compound that induces the intracellular release of zinc.

37 +) influx via capacitative Ca(2+) entry than intracellular release, whereas MHA eNOS activity was mor

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