ライフサイエンスコーパス: intracellular signaling molecule

1 Calcium is a universal intracellular signaling molecule.

2 paradigm for the specific recruitment of an intracellular signaling molecule.

3 Protein kinase C is an important intracellular signaling molecule.

4 KCNE accessory subunits and by an important intracellular signaling molecule.

5 Cyclic diguanylate (c-di-GMP) is a bacterial intracellular signaling molecule.

6 development because the ET(A) receptor is an intracellular signaling molecule.

7 ects occur in part via Nef interactions with intracellular signaling molecules.

8 ds on the concentrations and localization of intracellular signaling molecules.

9 specific targeting of Vav and other critical intracellular signaling molecules.

10 ation; however, each cytokine uses different intracellular signaling molecules.

11 xpression and ability to form complexes with intracellular signaling molecules.

12 raction of integrin cytoplasmic domains with intracellular signaling molecules.

13 lyphosphoinositides, the lipid precursors of intracellular signaling molecules.

14 through membrane-bound receptors and related intracellular signaling molecules.

15 d receptor tyrosine kinases and dysregulated intracellular signaling molecules.

16 r that interacts with numerous receptors and intracellular signaling molecules.

17 n multiple stimuli, including the binding of intracellular signaling molecules.

18 the cytoplasmic tails of the integrins with intracellular signaling molecules.

19 neurotrophic factor receptors and downstream intracellular signaling molecules.

20 nd stabilization of many protein kinases and intracellular signaling molecules.

21 ed by coordinate interactions among multiple intracellular signaling molecules.

22 rotein kinases, steroid receptors, and other intracellular signaling molecules.

23 ed by autophosphorylation and recruitment of intracellular signaling molecules.

24 enoids, which serve as lipid attachments for intracellular signaling molecules.

25 Anti-pS609 inhibited GPIb-IX binding to the intracellular signaling molecule, 14-3-3zeta.

26 of transcription 3 (STAT3) is the principal intracellular signaling molecule activated upon G-CSF li

27 ween an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1

28 It is proposed to act as an intracellular signaling molecule and can serve as the ca

29 The ability of TLRs to engage different intracellular signaling molecules and cross-talk with ot

30 hermore, VEGF-A-dependent phosphorylation of intracellular signaling molecules and endothelial prolif

31 en species (ROS) are recognized as important intracellular signaling molecules and have been implicat

32 Reactive oxygen species (ROS) act as intracellular signaling molecules and initiate apoptosis

33 ine (DA) receptors exert opposing actions on intracellular signaling molecules and often have dispara

34 ned, and flow cytometry was applied to stain intracellular signaling molecules and surface receptors.

35 lates the expression and activity of several intracellular signaling molecules and transcription fact

36 as a result of variegated surface receptor, intracellular signaling molecule, and transcription fact

37 ranscription factors, cell-surface proteins, intracellular signaling molecules, and modifiers of the

38 hat include specific cell-surface receptors, intracellular signaling molecules, and nuclear transcrip

39 ns between Trk receptor tyrosine kinases and intracellular signaling molecules are dictated both by p

40 d potentiation and rule out interaction with intracellular signaling molecules as a mechanism of comp

41 FcRgamma) and signals using many of the same intracellular signaling molecules as immune receptors.

42 These results implicate polyamines, emerging intracellular signaling molecules, as potential physiolo

43 C enzymes, in contrast, are regulated by the intracellular signaling molecules bicarbonate and calciu

44 se group behaviors are regulated by both the intracellular signaling molecule c-di-GMP and acylhomose

45 We also observe that another intracellular signaling molecule, Ca(2+), stimulates RAG

46 mate receptors mGluR1alpha and mGluR2/3; the intracellular signaling molecules calcineurin and calciu

47 s mGluR1alpha, mGluR2/3, and mGluR5; and the intracellular signaling molecules calcineurin, calcium c

48 IL-22 (rIL-22) enhances the expression of an intracellular signaling molecule, calgranulin A.

49 Moreover, we identified a novel intracellular signaling molecule, cAMP-response element

50 e cell corpse engulfment pathway mediated by intracellular signaling molecules CED-2 (homologous to t

51 R-B) and stimulates marked elevations of the intracellular signaling molecule, cGMP.

52 Identification of intracellular signaling molecules controlling this chann

53 Calcium, a ubiquitous intracellular signaling molecule, controls a diverse arr

54 These data position CD2AP as a major intracellular signaling molecule coordinating NGF signal

55 h the development of fluorescent sensors for intracellular signaling molecules coupled with improved

56 rved for strains with elevated levels of the intracellular signaling molecule cyclic di-GMP (c-di-GMP

57 zed in this study is increased levels of the intracellular signaling molecule cyclic di-GMP (c-di-GMP

58 ator of biofilm formation in bacteria is the intracellular signaling molecule cyclic diguanylate (c-d

59 The intracellular signaling molecule cyclic-di-GMP (c-di-GMP

60 The intracellular signaling molecule, cyclic-di-GMP (c-di-GM

61 tol phosphates are a family of water-soluble intracellular signaling molecules derived from membrane

62 Very few studies addressed how intracellular signaling molecules differentially specify

63 lr), Apolipoprotein receptor 2 (Apoer2), and intracellular signaling molecule Disabled-1 (Dab1).

64 an extracellular protein, Reelin (Reln), an intracellular signaling molecule, Disabled-1 (Dab1), and

65 The intracellular signaling molecule Dishevelled (Dvl) media

66 Arhgef1 is an intracellular signaling molecule expressed by myeloid ce

67 Thus, afadin is a key intracellular signaling molecule for cadherin recruitmen

68 a specific ROS, superoxide anion, acts as an intracellular signaling molecule for RGC death after axo

69 tor-associated kinases (IRAKs) are essential intracellular signaling molecules for transduction of TL

70 kin disease (45 cases and 3 cell lines) of 5 intracellular signaling molecules found in B cells.

71 own that Sod2 also serves as a source of the intracellular signaling molecule H(2)O(2).

72 sis of inositol hexakisphosphate (IP(6)), an intracellular signaling molecule implicated in the regul

73 kinases (MAPKs), ERK1 and ERK2, are critical intracellular signaling molecules important for transduc

74 Cyclic GMP (cGMP) is an important intracellular signaling molecule in the cardiovascular s

75 Reactive oxygen species (ROS) function as intracellular signaling molecules in a diverse range of

76 CTGF rapidly activates several intracellular signaling molecules in human mesangial cel

77 Since sHSP are known to be regulated by many intracellular signaling molecules in other cells types o

78 Therefore, we examined the role of these intracellular signaling molecules in our primary neurona

79 plasmic proteins that associate with several intracellular signaling molecules in regulation of vario

80 ed reorganization of the T cell membrane and intracellular signaling molecules in response to T cell

81 3 is a scaffolding protein, integrating many intracellular signaling molecules in specialized areas c

82 ine kinase inhibitors to examine the role of intracellular signaling molecules in Stx-mediated cytoki

83 st that PI(4,5)P2 and/or PI(4)P may serve as intracellular signaling molecules in these primary senso

84 However, ROS can also act as intracellular signaling molecules in vascular cells.

85 eading edges of pseudopods; 2) activation of intracellular signaling molecules including focal adhesi

86 d has been reported to interact with various intracellular signaling molecules including the epiderma

87 nal transduction is mediated by a complex of intracellular signaling molecules including TRADD, TRAF2

88 DOKL contains features of intracellular signaling molecules, including an N-termin

89 mulates breast tumorigenesis via a number of intracellular signaling molecules, including PI3K/AKT an

90 lation and translocation into the nucleus of intracellular signaling molecules, including Smad1, Smad

91 eptor in cells results in activation of many intracellular signaling molecules, including transcripti

92 ion factors, neurotransmitter receptors, and intracellular signaling molecules induced by repeated co

93 This suggests that Rac1 is an important intracellular signaling molecule involved in a spinal de

94 Ras is an intracellular signaling molecule involved in cell prolif

95 mitogen-activated protein kinase, is a major intracellular signaling molecule involved in inflammatio

96 cellular signal-regulated kinase (ERK) is an intracellular signaling molecule involved in nucleus acc

97 Mitogen-activated protein kinases (MAPK) are intracellular signaling molecules involved in cytokine s

98 However, the downstream intracellular signaling molecules involved in the develo

99 There is static information on the intracellular signaling molecules involved in these resp

100 It is not clear which intracellular signaling molecule is responsible for this

101 activated protein (MAP) kinase, an important intracellular signaling molecule, is activated in the gl

102 critical role in processing information from intracellular signaling molecules, is capable of undergo

103 n (SAP), an src homology 2 domain-containing intracellular signaling molecule known to interact with

104 pe II receptors to induce phosphorylation of intracellular signaling molecules known as Smads.

105 The expression of Grb, Ras, Raf, and Erk, intracellular signaling molecules known to be downstream

106 The development of methods to analyze intracellular signaling molecules on microarrays would m

107 Several genes encoding either intracellular signaling molecules or neurotransmitter re

108 transforms by binding to and activating key intracellular signaling molecules, phosphatidylinositol

109 ription in vivo can be mimicked by using the intracellular signaling molecule potassium glutamate in

110 cAMP, the intracellular signaling molecule produced in response to

111 ore than 90 other binding partners including intracellular signaling molecules, receptors, ion channe

112 hosphorylation by activated receptors, these intracellular signaling molecules recruit various downst

113 involves receptor-ligand pair clustering and intracellular signaling molecule recruitment with a coin

114 ) is characterized by underexpression of the intracellular signaling molecule RhoH.

115 the TGF-beta type I receptor (ALK-5) and its intracellular signaling molecule Smad3 were necessary fo

116 TGFBIp also induced phosphorylation of intracellular signaling molecules SRC, FAK, AKT, JNK and

117 owth factor-beta, which was dependent on the intracellular signaling molecule STAT1 but was independe

118 LPS-induced activation of intracellular signaling molecules, STAT1 Tyr-701, STAT1

119 Phosphorylation of proto-oncogenic intracellular signaling molecules Stat3, Erk1/2, and P38

120 ing prenylation of RhoA and effects on other intracellular signaling molecules such as NF-kappaB and

121 tant posttranslational lipid attachments for intracellular signaling molecules such as the Rho GTPase

122 thus they initiate signaling by interacting intracellular signaling molecules such as TNFR associate

123 eta through the timed activation of discrete intracellular signaling molecules, suggesting pathways i

124 (2)) is increasingly being appreciated as an intracellular signaling molecule that affects inflammato

125 One intracellular signaling molecule that integrates converg

126 is a SRC-homology-2 (SH2) domain-containing intracellular signaling molecule that is required for T

127 These findings demonstrate that GBDR1 is an intracellular signaling molecule that may play a role in

128 nosine monophosphate (c-di-GMP) is a dynamic intracellular signaling molecule that plays a central ro

129 rotein (WASP), a hematopoietic cell-specific intracellular signaling molecule that regulates the acti

130 kinases (MAPKs; also known as ERKs) are key intracellular signaling molecules that are ubiquitously

131 accompanied by up-regulation of several key intracellular signaling molecules that critically regula

132 pha, beta, gamma, and delta, are a family of intracellular signaling molecules that play important ro

133 now permit spatial distributions of specific intracellular signaling molecules to be observed in real

134 to delineate cell types simultaneously with intracellular signaling molecules to measure biological

135 s) by various contractile agonists activates intracellular signaling molecules to result in an increa

136 The intracellular signaling molecule TRAF6 is critical for T

137 ivator of NF-kappaB), which recruits various intracellular signaling molecules via specific motifs in

138 ulation in the acute phase of TBI, levels of intracellular signaling molecules were assessed followin

139 We found that these intracellular signaling molecules were complexed with P-

140 Genotoxic stresses activate intracellular signaling molecules, which lead to growth

141 Intracellular signaling molecules, which negatively regu

142 as ASC and PYCARD, TMS1 encodes a bipartite intracellular signaling molecule with proposed roles in

143 TMS1/ASC is an intracellular signaling molecule with proposed roles in

144 in cyclic adenosine monophosphate (cAMP), an intracellular signaling molecule with several known rest

145 kage between a GPI-anchored receptor and the intracellular signaling molecules with which it is physi