ライフサイエンスコーパス: intracellular transport

1 as single or few molecules, as characterizes intracellular transport.

2 for mitosis, maintenance of cell shape, and intracellular transport.

3 ent processes such as muscle contraction and intracellular transport.

4 namics of the cytoskeleton morphology during intracellular transport.

5 hedding new light on unresolved questions in intracellular transport.

6 of downstream signaling by integrins reduced intracellular transport.

7 vities to promote membrane tubulation during intracellular transport.

8 fect on particle morphology nor nanoparticle intracellular transport.

9 cargo they tow as part of microtubule-based intracellular transport.

10 , which serve as tracks for myosin-dependent intracellular transport.

11 s utilize a cytoskeleton for their entry and intracellular transport.

12 s regarding the role of motor cooperation in intracellular transport.

13 d processes, including molecular motor-based intracellular transport.

14 actively stabilizes the Tg dimer complex for intracellular transport.

15 X domain is a suitable mechanical anchor for intracellular transport.

16 olecular motors and lipids interact to drive intracellular transport.

17 n, endosomal release, carrier unpacking, and intracellular transport.

18 ubule motor kinesin-1 plays central roles in intracellular transport.

19 racterization of their attachment, entry and intracellular transport.

20 of determining the directions and speeds of intracellular transport.

21 sses including cell division, migration, and intracellular transport.

22 probe to examine their clustering states and intracellular transport.

23 ation, complex assembly and disassembly, and intracellular transport.

24 association with other proteins involved in intracellular transport.

25 d changes in cytoskeletal dynamics influence intracellular transport.

26 gos during clathrin-mediated endocytosis and intracellular transport.

27 -induced changes in MT levels facilitate its intracellular transport.

28 irus for an intact actin cytoskeleton during intracellular transport.

29 of microtubule dynamics, cell migration, and intracellular transport.

30 microtubule-based motor proteins that power intracellular transport.

31 olecules involved in different components of intracellular transport.

32 gestive of an impairment of kinesin-mediated intracellular transport.

33 eraction with other proteins in carrying out intracellular transport.

34 ng an underlying diversity of strategies for intracellular transport.

35 xtended Ras-like family), cell motility, and intracellular transport.

36 g alpha- or beta-structure that enable their intracellular transport.

37 up-regulated genes involved in apoptosis and intracellular transport.

38 inesin-2 that is best known for its roles in intracellular transport.

39 otentially be used as a noninvasive probe of intracellular transport.

40 variants both in surface mobility and during intracellular transport.

41 ng provide rich information on mechanisms of intracellular transport.

42 in protein turnover, cellular signaling, and intracellular transport.

43 as DNA replication, RNA/protein synthesis or intracellular transport.

44 a key pathway for cell polarization through intracellular transport.

45 Knockdown of bbs3 in zebrafish alters intracellular transport, a phenotype observed with knock

46 ryptococcus neoformans is thought to rely on intracellular transport, a process not fully explored in

47 o investigate further the role of A27 in IMV intracellular transport, a recombinant vaccinia virus wa

48 n microfluidic configurations stress-induced intracellular transport across the lipid membrane can be

49 olding of the heavy chain, while the rate of intracellular transport after assembly is unaffected.

50 lations, is able to efficiently avoid active intracellular transport along microtubules, and the subs

51 ic cells rely on long-lived microtubules for intracellular transport and as compression-bearing eleme

52 te if basic amino acids in MA play a role in intracellular transport and capsid-membrane interactions

53 in is a microtubule-based motor required for intracellular transport and cell division.

54 mation required for cytoskeletal remodeling, intracellular transport and cell locomotion.

55 urthermore, the UL20 protein is required for intracellular transport and cell surface expression of g

56 f self-quenched endocytic cargo to image the intracellular transport and degradation of endocytic car

57 c peptide binding to alphabetaI early during intracellular transport and demonstrate that proteolysis

58 particular, we emphasize how the activation, intracellular transport and downstream metabolism of fat

59 estion (Ssa2128-132A3) significantly reduced intracellular transport and fungicidal activity of Hst 5

60 lgi apparatus structure and its capacity for intracellular transport and glycoprotein modification.

61 g protein for Rab11, a GTPase that regulates intracellular transport and has specific roles in endoso

62 Yet, the implications of this strategy on intracellular transport and in vivo biodistribution rema

63 Motor-based intracellular transport and its regulation are crucial t

64 ify mutations that have a critical effect on intracellular transport and its regulation using mutagen

65 -linked glycosylation can influence both the intracellular transport and lipid-transporter activity o

66 lar functions including shape determination, intracellular transport and locomotion.

67 scovery of roles for arginine methylation in intracellular transport and mRNA splicing has focused at

68 processes, including synaptic transmission, intracellular transport and neuronal transcription.

69 processive molecular motors are critical for intracellular transport and organization, yet coordinati

70 al transduction, transcriptional regulation, intracellular transport and other processes, which likel

71 suggest a novel role for Pk2 in directional intracellular transport and our analyses show that PCP a

72 is known to interact with APP and affect its intracellular transport and processing.

73 ae, vesicular structures that participate in intracellular transport and signal transduction events,

74 important role in the spatial regulation of intracellular transport and signal transduction processe

75 e rigidity of cell membranes and controlling intracellular transport and signal transduction.

76 evels of Rab3a and Rab5 proteins involved in intracellular transport and sorting of nerve growth fact

77 evels of Rab3a and Rab5 proteins involved in intracellular transport and sorting of nerve growth fact

78 Here we characterize the intracellular transport and steady-state motor subunit c

79 Intracellular transport and surface display of integral

80 a protein associated with microtubule-based intracellular transport and synapse function.

81 Taken together, these results show that the intracellular transport and TGN localization of UL11 is

82 rane by an as yet unknown mechanism, undergo intracellular transport and then fuse with lysosomes, en

83 Intracellular transport and trafficking kinetics of the

84 me of membranes in the cell while optimizing intracellular transport and trafficking.

85 ansport-III (ESCRT-III) and is essential for intracellular transport and vacuole biogenesis.

86 that GRP94 knockdown cells are defective in intracellular transport and, consequently, negatively im

87 etter understand the motions contributing to intracellular transport and, more generally, the means f

88 tropic effect on growth, normal cytokinesis, intracellular transports and the production of several v

89 karyotic functions, including cell division, intracellular transport, and brain development.

90 elated with increased microtubule stability, intracellular transport, and ciliary assembly, yet a mec

91 systems essential for cell shape, movement, intracellular transport, and division.

92 required for normal expression, processing, intracellular transport, and incorporation into virions

93 served including cytoskeletal rearrangement, intracellular transport, and interferon signaling.

94 s of APP in neuronal development, signaling, intracellular transport, and other aspects of neuronal h

95 MTs) are essential for cell division, shape, intracellular transport, and polarity.

96 ortance of the STRA6 protein for the uptake, intracellular transport, and processing of retinol by th

97 ses, including cell motility, cell division, intracellular transport, and regulation of the microtubu

98 has a central role in morphology, migration, intracellular transport, and signaling.

99 ental processes including neurite outgrowth, intracellular transport, and synapse formation and plast

100 tosis, segregation in membrane microdomains, intracellular transport, and targeting to lysosomes regu

101 eared to be defective at an earlier stage of intracellular transport; and the remaining mutant (K33A

102 orks driving cell motility, endocytosis, and intracellular transport are assembled in seconds by the

103 conditions in which protein synthesis and/or intracellular transport are compromised.

104 influence of dynamic cytoskeletal states on intracellular transport are investigated in Dictyosteliu

105 are essential for cell shape, division, and intracellular transport are valid targets for anticancer

106 escence microscopy studies of virus particle intracellular transport, as a brighter particle will imp

107 r assays allow us to propose a framework for intracellular transport based on the binding by kinesin-

108 imide-sensitive factor, proteins involved in intracellular transport between the Golgi apparatus and

109 n, which is known to disrupt dynein-mediated intracellular transport, blocked TGFbeta-stimulated nucl

110 nelles and are a substrate for long-distance intracellular transport, but the functional linkages bet

111 e the force of actin polymerization to drive intracellular transport, but the role of actin in endocy

112 sin and dynein are fundamental components of intracellular transport, but their interactions when sim

113 Kinesin motor proteins drive intracellular transport by coupling ATP hydrolysis to co

114 n ideal model to study nuclear migration and intracellular transport by dynein and kinesin owing to i

115 large multisubunit complex, is required for intracellular transport by dynein; however, its cellular

116 tion, which impairs parasite viability after intracellular transport by LIT1.

117 folylpolyglutamate synthetase (FPGS) but not intracellular transport by the reduced folate carrier.

118 There is also evidence that cells regulate intracellular transport by tuning the number and/or rati

119 ality SPORT technique, the microtubule-based intracellular transport can be unambiguously identified

120 , cilia and flagella, and provide tracks for intracellular transport--can be highly bent by intracell

121 in many cell biological pathways, including intracellular transport, cell architecture, and primary

122 or a myriad of cellular functions, including intracellular transport, cell division, and cell shape.

123 y of cytoplasmic dynein, a motor involved in intracellular transport, cell division, and neurodevelop

124 les throughout eukaryotic biology, including intracellular transport, cell motility, cell division, d

125 skeleton plays an essential role in mitosis, intracellular transport, cell shape, and cell migration.

126 cal cellular and metabolic functions such as intracellular transport, cell signalling and protein tur

127 potential for exogenously added pDNA to bind intracellular transport cofactors may enhance the potenc

128 stabilizing oligomerization tags to maintain intracellular transport competence and F-triggering acti

129 retains its complete enzymatic activity and intracellular transport competence in the presence of th

130 ZFRPGR2 knockdown also resulted in an intracellular transport defect affecting retrograde but

131 Chemical inhibition of intracellular transport demonstrated that Golgi localiza

132 lternative explanation for observations that intracellular transport depends weakly on kinesin number

133 ALIX complex formation as a prerequisite for intracellular transport enabling viral capsid disassembl

134 within the Br module (cellular respiration, intracellular transport, energy coupled proton transport

135 motor cytoplasmic dynein powers a variety of intracellular transport events that are essential for ce

136 usly, confocal microscopy colocalization and intracellular transport experiments strongly suggested d

137 Neuronal microtubules support intracellular transport, facilitate axon growth, and for

138 lament bundles nucleated by formins, mediate intracellular transport for cell polarity establishment

139 Eukaryotic cells use microtubule-based intracellular transport for the delivery of many subcell

140 onent genes and the activation of genes with intracellular transport functions in cultured adult NSCs

141 f shielding against neutralizing antibodies, intracellular transport, G-F interactions, cell-cell fus

142 Protein-directed intracellular transport has not been observed in bacteri

143 l VP26-mCherry fusion for the study of viral intracellular transport.IMPORTANCE Alphaherpesviruses ar

144 nhibitors of the microtubule network reduced intracellular transport in both cell types, but movement

145 Intracellular transport in plant cells occurs on microtu

146 oles in establishing polarity and regulating intracellular transport in post-mitotic cells.

147 These findings reveal the importance of intracellular transport in steady-state lymph formation

148 and overexpression of BM2 causes a delay in intracellular transport in the exocytic pathway and caus

149 ates for the first time a functional role of intracellular transport in the optimal loading of MHC cl

150 r sequence to SCI biosynthesis, folding, and intracellular transport in transiently transfected HEK29

151 eral molecules that mediate lipid uptake and intracellular transport, including fatty-acid-binding pr

152 ost cell via the endocytic route, during its intracellular transport inside endosomes.

153 Intracellular transport involves the movement of organel

154 Intracellular transport involves the regulation of micro

155 Active intracellular transport is a central mechanism in cell b

156 Intracellular transport is a complex interplay of ballis

157 by interfering with cardiac contraction and intracellular transport is a dense microtubule network s

158 a broadly applicable tool for systems where intracellular transport is a key molecular mechanism.

159 Intracellular transport is an essential function in euca

160 Intracellular transport is essential for cytoplasm organ

161 Intracellular transport is essential for maintaining pro

162 Intracellular transport is largely driven by processive

163 Intracellular transport is mediated by molecular motors

164 in order to deliver their genome, and their intracellular transport is not fully understood.

165 Intracellular transport is typically bidirectional, cons

166 n; however, the molecular mechanism of their intracellular transport is unknown.

167 dies on the three major families involved in intracellular transport (kinesin-1, kinesin-2, and kines

168 e determinants in the cargo proteins and the intracellular transport machineries.

169 rt the first nonpeptide moiety that recruits intracellular transport machinery for nuclear targeting.

170 question in cell biology is how the general intracellular transport machinery is adapted to perform

171 of motors might work together as part of the intracellular transport machinery.

172 represent novel alleles of components of the intracellular transport machinery: specifically, kinesin

173 Thus, the intracellular transport mechanism of memapsin 2 is impor

174 The importance of such intracellular transport mechanisms is underscored by the

175 to experimental and theoretical analyses of intracellular transport mechanisms.

176 ng that numerous gene transcripts related to intracellular transport, mitochondria and the cytoskelet

177 accommodate ever-changing cellular needs for intracellular transport, morphogenesis, and migration.

178 ion (e.g., RNA polymerases and ribosomes) to intracellular transport (motor proteins such as kinesins

179 models, C-terminus-truncated DISC1 disrupts intracellular transport, neural architecture and migrati

180 o schizophrenia susceptibility by disrupting intracellular transport, neurite architecture and/or neu

181 lipid interactions, NaPCCP could function in intracellular transport of 120K in pollen tubes.

182 st roles for beta-arrestins in mediating the intracellular transport of a 7TMR to its obligate subcel

183 Here we characterized the early steps of intracellular transport of a fluorescent glycosphingolip

184 Unlike surface mobility, intracellular transport of betaNrxn(+) STVs was faster t

185 rect and reciprocal space to investigate the intracellular transport of branched gold nanostars (GNSs

186 Intracellular transport of cargo particles is performed

187 into the role of the COPII machinery in the intracellular transport of cargo, including chylomicrons

188 Intracellular transport of cargos along microtubules is

189 Intracellular transport of cargos, including many viruse

190 vement of a cyclophilin in the regulation of intracellular transport of CD147.

191 Nervous system function requires intracellular transport of channels, receptors, mRNAs, a

192 e transporter G1 (ABCG1) plays a role in the intracellular transport of cholesterol.

193 Understanding the mechanisms involved in the intracellular transport of chylomicrons and chylomicron-

194 V (MyoV) motors have been implicated in the intracellular transport of diverse cargoes including ves

195 srupted in yeast strains with defects in the intracellular transport of exogenous Q, the bc(1) comple

196 n most abundant in liver, is associated with intracellular transport of fatty acids, nuclear signalin

197 The initial step of the intracellular transport of G protein-coupled receptors,

198 Intracellular transport of Hst 5 was significantly impai

199 The intracellular transport of human immunodeficiency virus

200 e multiple particle tracking to quantify the intracellular transport of hundreds of individual nonvir

201 The utility of polyamines as vectors for the intracellular transport of iron chelators is further des

202 fect in neurons by causing the disruption of intracellular transport of key organellar cargo, such as

203 oteins function in concert to facilitate the intracellular transport of lipids from the lysosome to o

204 ter and binding proteins, and are capable of intracellular transport of long-chain FA.

205 tion of translated SR-B1 via reduced binding/intracellular transport of Lp(a).

206 plex plays a key role in the recognition and intracellular transport of many membrane proteins destin

207 Intracellular transport of membrane organelles occurs al

208 Clathrin-coated vesicles mediate sorting and intracellular transport of membrane-bound proteins.

209 l to study the distribution and mechanism of intracellular transport of Merlin and its mutants.

210 eacts with membrane phospholipids, enhancing intracellular transport of metals.

211 uggest that LFABP functions in the efficient intracellular transport of MG.

212 CPV reduced surface levels and inhibited the intracellular transport of MHC I early during infection.

213 MPV did not interfere with MHC expression or intracellular transport of MHC molecules.

214 Intracellular transport of motor-driven cargo faces the

215 suggesting that there was an increase in the intracellular transport of MVBs to the cell periphery by

216 e 6-phosphate receptor (CI-MPR) mediates the intracellular transport of newly synthesized lysosomal e

217 Intracellular transport of organelles and proteins is dr

218 data suggest that SFC is required for normal intracellular transport of PIN1 from the plasma membrane

219 The Sar1 family of proteins initiates the intracellular transport of proteins in COPII (coat prote

220 , an important process in the activation and intracellular transport of proteins vital for a wide var

221 Intracellular transport of proteins, their translocation

222 belongs to a family of proteins involved in intracellular transport of receptors to the plasma membr

223 Intracellular transport of recombinant adeno-associated

224 oated vesicles provide a major mechanism for intracellular transport of select cargo, which may be so

225 y and subcellular membrane fractionation the intracellular transport of silaffin Sil3.

226 that the rapid cellular uptake kinetics and intracellular transport of SNAs stem from the arrangemen

227 We showed previously that the intracellular transport of sphingolipids (SLs) is altere

228 Current models for the intracellular transport of Tau protein suggest motor pro

229 ons as a "dimerization domain," facilitating intracellular transport of Tg to the site of thyroid hor

230 olvement of an unconventional pathway in the intracellular transport of TGBp3.

231 Through direct binding, Ii also directs intracellular transport of the class II major histocompa

232 iciently blocking proteolytic processing and intracellular transport of the envelope protein.

233 SSP is critical for intracellular transport of the GPC complex to the cell s

234 step in infection, probably by facilitating intracellular transport of the HIV-1 ribonucleoprotein c

235 d at a subsequent step by blocking efficient intracellular transport of the virus.

236 The intracellular transport of therapeutic gene carriers is

237 The intracellular transport of these receptors has tradition

238 We demonstrate intracellular transport of this peptide, its binding and

239 e investigate how these mutations affect the intracellular transport of TREM2.

240 ne of the engineered UL20 mutations affected intracellular transport of UL20p to trans-Golgi network

241 In bacteria, ParABS systems mediate intracellular transport of various cargos, including chr

242 ein is the motor protein responsible for the intracellular transport of various organelles and other

243 on of the polyamine backbone as a vector for intracellular transport of various pharmacophores has fo

244 Intracellular transport of vesicles and organelles along

245 ctures that serve as tracks for myosin-based intracellular transport of vesicles and organelles in bo

246 r proteins are involved in cell division and intracellular transport of vesicles and organelles, and

247 glycans not only orchestrate the folding and intracellular transport of viral glycoproteins but also

248 s system is dependent upon the long-distance intracellular transport of viral particles in axons.

249 roteins, not only play a central role in the intracellular transport of virus particles but also regu

250 Intracellular transport of virus particles in neurons is

251 Analysis of the assembly and intracellular transport of viruses as well as of the rol

252 tical for proper protein oligomerization and intracellular transport or for membrane fusion triggerin

253 o elucidate the mechanisms that regulate the intracellular transport or trafficking of hERG, because

254 atively little is known about their folding, intracellular transport, or secretion from mammalian cel

255 motors and polymer ratchets as they mediate intracellular transport, organelle dynamics, cell locomo

256 echanism can control a biochemically complex intracellular transport pathway.

257 The study of intracellular transport pathways at epithelial cell barr

258 illuminated an important role for defects in intracellular transport pathways to lysosomes.

259 min function in membrane fission in distinct intracellular transport pathways, but whether their func

260 organization, cell biogenesis, development, intracellular transport, phospholipid metabolism, protei

261 Regulation of intracellular transport plays a role in a number of proc

262 Intracellular transport plays an essential role in maint

263 argoes are resolved accurately to render the intracellular transport process in live cells.Distinguis

264 tion in the fly eye and disrupts fundamental intracellular transport processes that are likely to con

265 irus that enters neuronal cells and utilizes intracellular transport processes to establish infection

266 propose this dependence has implications for intracellular transport processes, especially for bidire

267 S-nitrosylation reactions that can regulate intracellular transport processes.

268 We conclude that ClC-3 is primarily an intracellular transport protein that is transiently inse

269 compartment and are related to prototypical intracellular transport proteins.

270 y tunable and have more substantial roles in intracellular transport regulatory mechanisms compared w

271 uired for entry, membrane translocation, and intracellular transport remain to be elucidated.

272 he extent to which motor copy number affects intracellular transport remains controversial.

273 Functions, like signaling and intracellular transport, require the abilities to bind t

274 tors, we found that liposome endocytosis and intracellular transport required clathrin, dynamin, an i

275 interferes with at least two steps in Pmel17 intracellular transport, resulting in defects in melanos

276 ane fusion, but assigning SNAREs to specific intracellular transport routes is challenging with curre

277 echanosensors in diverse functions including intracellular transport, signaling, cell migration, musc

278 Spindly-like motifs in adaptors involved in intracellular transport suggests a common mechanism for

279 mate receptor - prominently regulating early intracellular transport, synaptic targeting and anchorin

280 their overall organization, regulation, and intracellular transport that both facilitate and modulat

281 sin-1 is a dimeric motor protein, central to intracellular transport, that steps hand-over-hand towar

282 d surface expression, indicating a defect in intracellular transport, though this mutation had no eff

283 l flow strength or flow channel geometry for intracellular transport through a MS channel.

284 al toxins are believed to undergo retrograde intracellular transport through the Golgi apparatus to t

285 anging from structural to enzymatic and from intracellular transport to chaperones, have been describ

286 ce proteins on Candida albicans, followed by intracellular transport to cytoplasmic effectors leading

287 asite adapted a process well established for intracellular transport to mediate the extracellular mov

288 increasingly common in studies ranging from intracellular transport to the movements of whole organi

289 ealed that viral attachment, cell entry, and intracellular transport to the nuclear periphery still o

290 ause long QT syndrome (LQT2) by reducing the intracellular transport (trafficking) of the channel pro

291 insights into the functional constraints on intracellular transport under which cells have evolved c

292 of a multi-modular protein whose function in intracellular transport underlies the growth, differenti

293 Fusion of intracellular transport vesicles requires soluble N-ethy

294 nnel is delivered to the plasma membrane via intracellular transport vesicles, it remains localized a

295 hesizing that mutant COPA leads to defective intracellular transport via coat protein complex I (COPI

296 Intracellular transport via processive kinesin, dynein,

297 Intracellular transport via the microtubule motors kines

298 o probe the forces exerted on cargoes during intracellular transport, we examined latex beads phagocy

299 ly in T. brucei, at least 30 are involved in intracellular transport, whereas fewer than eight are li

300 d GTPase Rab8 plays an important role in the intracellular transport, while we have previously shown