ライフサイエンスコーパス: intrachain

1 ins (interchain) and within a polymer chain (intrachain).

2 this behavior is sensitive to the details of intrachain and chain-solvent interactions, the collapse

3 The emissions are caused by intrachain and interchain aurophilic interactions betwee

4 cluded absence of the cysteines required for intrachain and interchain disulfide bonds.

5 The different intrachain and interchain energy transfer time scales ex

6 omagnetic (AF) ordering at T(N) = 7 K due to intrachain and interchain exchange interactions.

7 Stable intrachain and interchain H-bonds are identified as a fu

8 tematic Mn variation greatly influences both intrachain and interchain interactions and ultimately th

9 charge separation pathways originating from intrachain and interchain species.

10 ity measurements demonstrate the presence of intrachain antiferromagnetic (2) and ferromagnetic (3-5)

11 one-dimensional S = 1 Heisenberg chains with intrachain antiferromagnetic coupling.

12 0.59) scaling can simultaneously accommodate intrachain attractions and detectable long-range contact

13 a random coil or, in the presence of strong intrachain attractions, a so-called 'molten globule'.

14 s in ICBS interfaces are similar to those in intrachain beta-sheet interfaces.

15 Normal VWF has a Cys1149-Cys1169 intrachain bond.

16 , the newly synthesized Vp1 monomers acquire intrachain bonds as they fold and begin to interact.

17 are reoxidized to reform covalent inter- and intrachain bonds.

18 ium groups of conserved arginines in the two intrachain cAMP-binding sites of regulatory (R) subunit

19 se, its electronic states have a predominant intrachain character.

20 e excited states, including the formation of intrachain charge transfer excitons.

21 polymers, and demonstrate the importance of intrachain charge transport in plastic electronics.

22 ns are aligned along the fiber to facilitate intrachain charge transport.

23 significant "internal friction" arising from intrachain collisions.

24 ined using these data plus an additional 509 intrachain constraints per chain.

25 e 50-58 loop, in beta-turns, and in specific intrachain contacts between amino- and carboxyl domains.

26 anges to the pattern of local and long-range intrachain contacts.

27 A competition from intrachain coupling has also been demonstrated by compar

28 oteins has frequently been limited to use as intrachain covalent staples that reinforce existing stru

29 myosin containing RLC-C165, the yield of one intrachain cross-linked band decreased significantly whe

30 these distance constraints, as well as three intrachain cross-links, were used to further refine an i

31 This suggests that the intrachain Cys359/Cys384 disulfide bond within C9 is not

32 overy from serum, revealed that the unpaired intrachain cysteine residues (Cys22-Cys96) reformed thei

33 ts five occupied glycosylation sites and six intrachain cystine bridges with Cys-158 of the very flex

34 were decomposed into interchain motions and intrachain deformations.

35 onation of two indole side chains to form an intrachain delta(1),delta(1)'-ditryptophan derivative.

36 ing conformational transitions is set by the intrachain diffusion coefficient, D.

37 and denaturant concentration on the rate of intrachain diffusion in an unfolded protein.

38 ide] = 5.4 M) that is limited by the rate of intrachain diffusion to bring the Zn-porphyrin and Ru co

39 t (5 micros) is near the predicted value for intrachain diffusion.

40 llapse may in turn be limited by the rate of intrachain diffusion.

41 invariant cysteine that is required for the intrachain disulfide bond and, on the other chromosome,

42 red mutant of III3 that was stabilized by an intrachain disulfide bond did not interact with anastell

43 The effect was preceded by reduction of the intrachain disulfide bond encompassing the platelet-bind

44 ing one participating Cys to Ser, precluding intrachain disulfide bond formation, retained full activ

45 tion, acetylation, proteolytic cleavage, and intrachain disulfide bond formation.

46 5 and Cys-50, which are predicted to form an intrachain disulfide bond in Tva, drastically reduced th

47 This suggests that formation of an intrachain disulfide bond is required for SPC-mediated c

48 dimentation equilibrium and CD and formed an intrachain disulfide bond predicted from the structure o

49 (IgG1) contains 12 domains, and each has an intrachain disulfide bond that connects the two layers o

50 Cys326, reasoning that Cys321 would form an intrachain disulfide bond with Cys326 as in prekallikrei

51 that the propeptide should form a transient intrachain disulfide bond with the D3 domain before mult

52 41-kDa monomeric intermediate containing an intrachain disulfide bond(s).

53 nalyses revealed that C95 and C105 formed an intrachain disulfide bond, whereas C95 by itself produce

54 the cysteine is thought to be involved in an intrachain disulfide bond.

55 tide chains linked by two interchain and one intrachain disulfide bond.

56 three pairs of cysteine residues involved in intrachain disulfide bonding, a cysteine near the carbox

57 unique three-looped trefoil motif formed by intrachain disulfide bonds among six conserved cysteine

58 magglutinin major subunit that contains four intrachain disulfide bonds and is connected to the virio

59 These intrachain disulfide bonds are shielded from solvents un

60 op structure of the trefoil motif, formed by intrachain disulfide bonds in a 1-5, 2-4, 3-6 configurat

61 inically approved mucolytic drug) can reduce intrachain disulfide bonds in large polymeric proteins.

62 n with reducing agents to break the numerous intrachain disulfide bonds in Muclin's scavenger recepto

63 hese data therefore suggest that tubulin has intrachain disulfide bonds in the alpha- and beta-subuni

64 y interchain disulfide bonds but has 239-242 intrachain disulfide bonds instead.

65 The four cysteines may thus form two intrachain disulfide bonds integral to the secondary str

66 he two inter heavy chain disulfide bonds and intrachain disulfide bonds was not changed significantly

67 ry, and amino acid sequencing, the remaining intrachain disulfide bonds were characterized: Cys(1961)

68 ture, as assessed by the formation of native intrachain disulfide bonds, only approximately 50% of na

69 in disulfide bond, while for peptides having intrachain disulfide bonds, the reaction products typica

70 Each half-molecule has 6 intrachain disulfide bonds, which form loops in the carb

71 ithin lysosomes, and reduction of inter- and intrachain disulfide bonds.

72 5: four conserved cysteines allowing for two intrachain disulfide bonds.

73 The chains are linked by 29 inter- and intrachain disulfide bonds.

74 ck interheavy chain disulfide bonds and form intrachain disulfide bonds.

75 ce duplication and 10 cysteines forming five intrachain disulfide bonds.

76 ed recognition element tethered by insulin's intrachain disulfide bridge.

77 ith an associated kappa light chain with two intrachain disulfide bridges in each of the heavy and li

78 and constant domains in addition to the two intrachain disulfide bridges shared with mouse and human

79 nd that CD4 retro-translocates with oxidized intrachain disulfide bridges, and only upon proteasomal

80 The other Cys residues exclusively form intrachain disulfide bridges.

81 immunoglobulin-like domains containing three intrachain disulfide bridges.

82 s of scrambling were identified, such as the intrachain disulfide for CxxC in the heavy chain, and th

83 where 46% of the antibody was trapped in the intrachain disulfide form.

84 f a novel subvariant of IgG2-B containing an intrachain disulfide linkage in the lower hinge region i

85 ning six conserved cysteines that form three intrachain disulfide linkages known as the tumor necrosi

86 es likely are either reduced or form a tight intrachain disulfide loop rather than contribute to a me

87 cysteine masked within the native Ag via an intrachain disulfide, the latter of which is reduced dur

88 ney cells, the propeptide and D'D3 formed an intrachain disulfide-linked species in the endoplasmic r

89 ffective in the reduction of intramolecular (intrachain) disulfide bonds.

90 In addition to mapping the 4 inter- and 12 intrachain disulfides (total 16), the identification of

91 of the B chain of ricin, the elimination of intrachain disulfides in CdtC and CdtA by genetic replac

92 A diminished role for intrachain disulfides in stabilizing CdtA and CdtC may h

93 gests it may be involved in the reduction of intrachain disulfides prior to retrotranslocation.

94 hese challenges by demonstrating that strong intrachain donor-acceptor interactions are a key design

95 ell-mixed sequences, and in these sequences, intrachain electrostatic repulsions and attractions are

96 polymer leads to a quenching of short-delay intrachain emission and an increase in the long-delay ph

97 We find that rapid intrachain energy migration toward complex sites with th

98 d polymers such as MEH-PPV where much slower intrachain energy transfer was reported.

99 FM exchange behavior over 1.8-300 K with an intrachain exchange constant of Jchain/k = +22 K.

100 lymers show a substantial enhancement in the intrachain exciton migration rate, which is attributed t

101 ng between the chains but rather to dominant intrachain excitonic coupling that greatly reduces the m

102 radical ions results in RDD with significant intrachain fragmentation of acyl moieties.

103 ions does not give rise to product ions from intrachain fragmentation of the fatty acyl moieties.

104 s an addition to all relaxation times due to intrachain friction sources.

105 ils is a network of hydrogen (H) bonds: both intrachain H-bonds between neighboring monomers of a sin

106 ing that equilibration of the interchain and intrachain hinge disulfide pairing was not always attain

107 We study the occurrence and effect of intrachain homocoupling defects in alternating push-pull

108 The loss of the longer chains involves intrachain hydride transfer from the C(alpha)-H bond to

109 Thus, increased intrachain hydrogen bonding guides secondary structure a

110 at differences in hydrogen bond strength for intrachain hydrogen bonds and amide...water hydrogen bon

111 Since it is extended, flexible, lacks intrachain hydrogen bonds and is fully hydrated in aqueo

112 ctively preventing formation of the regular, intrachain hydrogen bonds that stabilize peptide alpha-h

113 igomers become more rigid and likely to form intrachain hydrogen bonds, like those found in crystals.

114 The solenoid is reinforced by intrachain hydrogen bonds, side-chain salt bridges, and

115 ckbone chirality and their inability to form intrachain hydrogen bonds.

116 The simulations indicate that intrachain interactions and dihedral angle rotation corr

117 n be understood only by considering specific intrachain interactions and intermediate (and hierarchic

118 Only intrachain interactions are considered, including one ad

119 ctions were observed, as well as stabilizing intrachain interactions between residues of opposite cha

120 into compact conformations due to extensive intrachain interactions between Ub subunits, this topolo

121 favorable chain-solvent interactions causes intrachain interactions to be repulsive, on average.

122 epeats are highly dynamic random coils, lack intrachain interactions, and exhibit significant entropi

123 Stiff polymers with strong intrachain interactions, in contrast, are expected to co

124 istical mechanical calculations of inter and intrachain interactions.

125 the folding free energy surface arising from intrachain interactions.

126 es as well as an estimate of the strength of intrachain interactions.

127 ns or binding of MDM2 changed the pattern of intrachain kinetics.

128 A procedure for the efficient preparation of intrachain-linked polypeptides is presented, and it is d

129 Measuring the rate at which this 62 residue intrachain loop forms under both folding and unfolding c

130 ng beta integrin subunits and lies within an intrachain loop implicated in subunit association.

131 Cysteines, postulated to form an intrachain loop, are present in the IgSF domain and are

132 The intrachain loops are conserved in fibrinogens of differe

133 , the formation of short (<10 peptide bonds) intrachain loops around the heme group.

134 d mutagenesis, the cysteines, which form the intrachain loops, to serine or alanine.

135 el mechanism for chitin binding, mediated by intrachain LysM dimerization, leading to a chitin-bindin

136 om the appropriate balance of interchain and intrachain metal ion coordination by Gla residues in sim

137 The conformational diffusion coefficient for intrachain motions in biopolymers, D, sets the timescale

138 ide exhibits 123 sequential and medium range intrachain NOE cross peaks per chain, characteristic of

139 le and by, second, calculating intraplane or intrachain nucleus-independent chemical shifts that quan

140 charge state) generated from peptides having intrachain peptides were subjected to collision-induced

141 SDS-PAGE showed that, for RLC-C18, the intrachain photo-cross-linking in myosin was inhibited b

142 These structures allow the study of possible intrachain photoinduced charge separation, in contrast t

143 thesized pi-conjugated polymers that contain intrachain platinum (Pt) atoms separated by one (Pt-1) o

144 ugated polymers with strong SOC that contain intrachain platinum atoms, to weak SOC polymers, to C60

145 ss peaks, which therefore identify reference intrachain proximities.

146 and folded states is expected to arise from intrachain reorganization in the protein.

147 r arginine, which is probably involved in an intrachain salt bridge, has no effect on the assembly.

148 ectron donor, it assists the formation of an intrachain singlet exciton that has a strong charge-tran

149 By removing 6-O-sulfates from specific HS intrachain sites on the cell surface, Sulf1 has been sho

150 c Heisenberg S = 1/2 linear chain model with intrachain spin coupling J = -52.3 cm(-1).

151 activation barrier that separates the local intrachain state and the excimer-like state in the forme

152 ility of this material to adopt higher order intrachain structures.