ライフサイエンスコーパス: intraepidermal

1 Intraepidermal and corneal nerve fiber lengths were redu

2 and hair follicle palisades as well as some intraepidermal and free myelinated nerve endings.

3 ity scores, were observed when comparing the intraepidermal and superficially invasive portions with

4 phils, resulting in formation of subcorneal, intraepidermal, and subepidermal pustules.

5 disorders of skin fragility characterized by intraepidermal blistering upon mild mechanical trauma.

6 a mechano-bullous disorder characterized by intraepidermal blistering within the basal keratinocytes

7 inheritable skin disorders characterized by intraepidermal blistering, epidermal hyperkeratosis, or

8 ents with epidermolysis bullosa simplex with intraepidermal blistering.

9 une blistering skin disease characterized by intraepidermal blisters and circulating autoantibodies d

10 /7 inhibitor, protected mice from developing intraepidermal blisters and clinical disease induced by

11 At 2 days of age, mutant animals exhibit intraepidermal blisters and erosions at sites of trauma,

12 TUNEL-positive epidermal cells appear before intraepidermal blisters.

13 squamous cell carcinoma or Bowen's disease (intraepidermal carcinoma) present and confirmed in the b

14 of CD4+ T cells revealed CD69 expression by intraepidermal CD4+ as well as CD8+ T cells.

15 hat contains a unique population of immature intraepidermal dendritic cells (DCs) called Langerhans c

16 cted not only on many thin-caliber axons and intraepidermal endings but also on many large-caliber ax

17 independent and is associated with increased intraepidermal expression of IL-22 and the presence of g

18 Advances in the analysis of intraepidermal fiber densities could shorten the time co

19 roduct) 9.5 were used, with the exception of intraepidermal fibres which were not detected in the maj

20 induced increases in PGP 9.5 immunoreactive intraepidermal fine nerve endings that were normalized a

21 Intraepidermal (IENFD), sweat gland (SGNFD), and pilomot

22 vation and proliferation, we discovered that intraepidermal immunocytes, including both CD4 and CD8+

23 ous cytokines and chemokines responsible for intraepidermal inflammation independent of TNFalpha.

24 pathway and mediates chemokine induction and intraepidermal inflammation independently.

25 r, inhibiting AP-1 in vivo does not abrogate intraepidermal inflammation.

26 osis in transgenic skin, but only TPA evokes intraepidermal inflammation.

27 Intraepidermal innervation using PGP 9.5 immunostaining

28 presence of basal melanocyte hyperplasia and intraepidermal Langerhans cells.

29 rficial spreading melanoma, characterized by intraepidermal large nests.

30 ized by extensive neutrophil accumulation in intraepidermal lesions accompanied by a mononuclear infi

31 nd marker expression mimicking that of human intraepidermal MCC.

32 protein shifts from nuclear localization in intraepidermal melanoma cells to nuclear and cytoplasmic

33 A572V disease is epidermotropic and produces intraepidermal microabscesses.

34 ific for melanocytes and nerve fibers showed intraepidermal nerve endings in contact with melanocytes

35 pathological changes using the technique of intraepidermal nerve fiber (IENF) assessment and the nov

36 Intraepidermal nerve fiber (IENF) density was most sever

37 landin content, markers of inflammation, and intraepidermal nerve fiber (IENF) density were measured

38 nts [73%; 95% CI, 44% to 92%]; P < .001) and intraepidermal nerve fiber density (4 patients [27%; 95%

39 ther alterations in cutaneous LC density and intraepidermal nerve fiber density (IENFD) are present i

40 dorsal root ganglion (DRG) inflammation and intraepidermal nerve fiber density (IENFD) loss.

41 e, and nerve conduction studies, and reduced intraepidermal nerve fiber density (IENFD) plus abnormal

42 Intraepidermal nerve fiber density (IENFD) was assessed

43 Reduced intraepidermal nerve fiber density (IENFD) was seen in a

44 nitored by serial skin biopsies to determine intraepidermal nerve fiber density (IENFD).

45 urophysiology, QST, corneal sensitivity, and intraepidermal nerve fiber density (IENFD).

46 Taken together, our findings suggest that intraepidermal nerve fiber density and changes in NCV an

47 ht-based equivalent of human dose, increased intraepidermal nerve fiber density and improved multiple

48 Secondary outcomes included intraepidermal nerve fiber density and nerve conduction

49 Low-dose Metanx increased intraepidermal nerve fiber density but did not prevent m

50 Intraepidermal nerve fiber density declined maximally by

51 Valuable markers of neuropathy such as intraepidermal nerve fiber density from skin biopsies ha

52 altered sensory nerve action potentials and intraepidermal nerve fiber density had a shorter CNFL (P

53 e total number of regenerating axons and the intraepidermal nerve fiber density in the skin were redu

54 ies in the same participants showed that the intraepidermal nerve fiber density is lower in the finge

55 on and electrochemical skin conductance) and intraepidermal nerve fiber density quantification.

56 subjects had skin biopsies for evaluation of intraepidermal nerve fiber density.

57 myelin changes accompanied by a reduction in intraepidermal nerve fiber density.

58 V and alleviation of thermal hypoalgesia and intraepidermal nerve fiber loss but not tactile allodyni

59 a, and thermal hypoalgesia in the absence of intraepidermal nerve fiber loss or axonal atrophy.

60 iculum stress, peripheral nerve dysfunction, intraepidermal nerve fiber loss, and sciatic nerve and s

61 Intraepidermal nerve fiber loss, axonal degeneration, im

62 ial nerve myelinated fiber diameter, but not intraepidermal nerve fiber loss.

63 ity, thermal hypoalgesia, and a reduction in intraepidermal nerve fiber profiles.

64 onduction velocity, thermal hypoalgesia, and intraepidermal nerve fiber profiles.

65 to small-diameter peripheral nerve axons and intraepidermal nerve fibers (IENF).

66 All of the drugs ablated intraepidermal nerve fibers and produced axonopathy, wit

67 Since many intraepidermal nerve fibers are afferent nerves that act

68 ypothesize that patients with SFN would lose intraepidermal nerve fibers at the distal leg more quick

69 ciated with severe DRG pathology and loss of intraepidermal nerve fibers in SIV-infected macaques.

70 stimuli) and pathological (transient loss of intraepidermal nerve fibers) signs of peripheral neuropa

71 nd a remarkable ( approximately 78%) loss of intraepidermal nerve fibers.

72 nerve conduction studies and skin biopsy for intraepidermal nerve fibre assessment.

73 members and revealed in six of them reduced intraepidermal nerve fibre density consistent with small

74 Evaluation of intraepidermal nerve fibre density showed a striking los

75 tive sprouting was assessed by the return of intraepidermal nerve fibre density through regenerative

76 The intraepidermal nerve fibre density was markedly reduced

77 gp120 and/or ddC and there is a reduction in intraepidermal nerve fibre density, comparable to that s

78 nt neuropathies lead to a clear reduction in intraepidermal nerve fibre density, which was independen

79 skin biopsy showed a significant decrease in intraepidermal nerve fibre density.

80 nd nerve action potential amplitude, loss of intraepidermal nerve fibres and significant degeneration

81 erproliferation, acanthosis, hyperkeratosis, intraepidermal neutrophil microabscesses, and increased

82 Intraepidermal neutrophilic IgA dermatosis, a rare skin

83 glein 3 is identified as a target antigen in intraepidermal neutrophilic IgA dermatosis.

84 -PKCalpha mice) exhibit acute CXCR2-mediated intraepidermal neutrophilic inflammation and a strong ep

85 K5-PKCalpha transgenic mice exhibit severe intraepidermal neutrophilic inflammation and disruption

86 pressing PKCalpha in the skin exhibit severe intraepidermal neutrophilic inflammation and keratinocyt

87 5-PKCalpha mice) exhibit an inducible severe intraepidermal neutrophilic inflammation and systemic ne

88 hemokines regulated by PKCalpha that promote intraepidermal neutrophilic inflammation, a condition th

89 ly benign lesions, intermediate lesions, and intraepidermal or invasive melanomas.

90 complex disorders that are characterized by intraepidermal (pemphigus) and subepidermal blistering (

91 ancroid are characterized by the presence of intraepidermal pustules, keratinocyte cytopathology, and

92 In two patients, intraepidermal resident CD8+ T cells were induced to pro

93 eficit was greater compared to reductions in intraepidermal sensory innervation of adjacent epidermis

94 yndrome which is characterized by a specific intraepidermal separation of layers of the skin.

95 Intraepidermal T cell migration and related lesion forma

96 ided in a temporal fashion with depletion of intraepidermal T cells in all five patients studied.

97 An intraepidermal Wnt signal is necessary and sufficient fo

98 We hypothesized that intraepidermal Wnt signaling might influence LC developm