ライフサイエンスコーパス: intraepithelial

1 tion of children with STRA exhibit increased intraepithelial airway neutrophilia that correlated with

2 In conclusion, our findings demonstrate that intraepithelial and lamina propria CD8(+) T cells exhibi

3 n systemic and in mucosal tissues, including intraepithelial and lamina propria lymphocytes of the sm

4 lial cells and also establishes serous tubal intraepithelial carcinoma as the precursor lesion to hig

5 carcinoma appears to develop from an occult intraepithelial carcinoma in the fimbria of the fallopia

6 fallopian tube lesions, called serous tubal intraepithelial carcinoma.

7 n tube lesions (p53 signatures, serous tubal intraepithelial carcinomas (STICs), and fallopian tube c

8 small precursor lesions called serous tubal intraepithelial carcinomas (TICs, or more specifically,

9 whereas many type II carcinomas develop from intraepithelial carcinomas in the fallopian tube and, as

10 Intraepithelial carcinomas of the fallopian tube are put

11 ted primarily in the lamina propria, whereas intraepithelial CD4(+) T cells (CD4(IELs)), which also e

12 r with a tryptophan-rich diet, can reprogram intraepithelial CD4(+) T cells into immunoregulatory T c

13 abolished the good prognosis associated with intraepithelial CD8(+) cells.

14 alphaEbeta7) integrin induction in activated intraepithelial CD8(+) T lymphocytes.

15 These results demonstrate the importance of intraepithelial cell migration in proper positioning of

16 Mutant forms of PIK3CA may also stimulate intraepithelial cell movement, which could contribute to

17 sustaining junctional tension and inhibiting intraepithelial cell movement.

18 p53 identified residual atypical intraepithelial cells when conjunctival epithelial sloug

19 ngly affected the CD8alphaalpha cells in the intraepithelial compared with the adjacent lamina propri

20 hology confirmed malignant melanoma, with no intraepithelial component or associated melanosis.

21 separate conjunctival biopsy specimens with intraepithelial cytologic atypia, adipophilin results we

22 ive immunity contribute to the activation of intraepithelial cytotoxic T cells and the development of

23 Intraepithelial cytotoxic T cells from potential celiac

24 Intraepithelial cytotoxic T cells from relatives of pati

25 We analyzed epithelial cells and intraepithelial cytotoxic T cells in family members of p

26 review will examine the mechanisms by which intraepithelial cytotoxic T cells mediate tissue destruc

27 t in synergy with epithelial stress to allow intraepithelial cytotoxic T cells to kill epithelial cel

28 Intraepithelial cytotoxic T cells were isolated and leve

29 n in sensory nerve density and the number of intraepithelial DCs in unwounded (UW) corneas.

30 Evaluation of intraepithelial duodenal lymphocytosis (IDL) is importan

31 Intraepithelial dysplasia of the oral mucosa typically o

32 Epithelial changes seen were intraepithelial edema, fibrosis, epithelial downgrowths,

33 QAX576 significantly improved intraepithelial esophageal eosinophil counts and dysregu

34 Among 9 cases exhibiting intraepithelial extensions, 6 showed mostly granular pos

35 ons can arise from the direct stimulation of intraepithelial free nerve endings or indirectly through

36 ma-producing lineages such as Th1, ILC1, and intraepithelial gammadelta T cells.

37 land 2 genes (especially spiC) and increased intraepithelial growth in a T3SS-2-dependent manner.

38 ut not IL-15 receptor-alpha, indicating that intraepithelial ILC1 are distinct from conventional NK c

39 nd (SG) ILCs as well as liver and intestinal intraepithelial ILC1 have markers that denote tissue res

40 nt memory CD8(+) T cells share this profile, intraepithelial ILC1 may be their innate counterparts.

41 In mice, intraepithelial ILC1 were distinguished by CD160 express

42 ently noted in tumor cells but was common in intraepithelial immune cells and more frequent in POLE a

43 E1199 were evaluated for density of TILs in intraepithelial (iTILs) and stromal compartments (sTILs)

44 e anal cancer precursor, high-grade squamous intraepithelial lesion (HSIL), frequently regresses spon

45 significance (ASCUS) and low-grade squamous intraepithelial lesion (LSIL) triage study (ALTS), who w

46 HIV-infected women with a low-grade squamous intraepithelial lesion (LSIL; benchmark indication for c

47 ble analysis, a history of cervical squamous intraepithelial lesion (odds ratio [OR], 4.2; 95% confid

48 outcomes: high-risk HPV prevalence; squamous intraepithelial lesion (SIL) or cervical intraepithelial

49 Undetermined Significance/Low-Grade Squamous Intraepithelial Lesion Triage Study provided blood sampl

50 termined significance and low-grade squamous intraepithelial lesion) and CIN1+ was also significant.

51 cells, cannot exclude a high-grade squamous intraepithelial lesion, low-grade squamous intraepitheli

52 a higher burden of anal high-grade squamous intraepithelial lesions (HSIL) and anal cancer (AC) comp

53 low-grade and 1282 with high-grade squamous intraepithelial lesions (HSILs) diagnosed cytologically;

54 associated with risk of high-grade squamous intraepithelial lesions (HSILs).

55 focal intra-anal tissue high-grade squamous intraepithelial lesions (HSILs).

56 rs and/or progression to high-grade squamous intraepithelial lesions (ie, cervical intraepithelial ne

57 significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL) who were triaged with tes

58 significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL) who were triaged with tes

59 ned significance (ASCUS), low-grade squamous intraepithelial lesions (LSILs), and high-grade SILs (HS

60 vical cancer precursors (high-grade squamous intraepithelial lesions [HSILs]).

61 nificance (ASC-US) and patients negative for intraepithelial lesions and malignancy (NILM) (P </= 0.0

62 ad a higher frequency of advanced pancreatic intraepithelial lesions and more foci of invasive cancer

63 AS mutations, and reliably detect pancreatic intraepithelial lesions in mice despite negative signals

64 increased through ASCUS, low-grade squamous intraepithelial lesions, CIN1, and CIN2 (18%-25%), up to

65 s intraepithelial lesion, low-grade squamous intraepithelial lesions, or high-grade squamous intraepi

66 raepithelial lesions, or high-grade squamous intraepithelial lesions.

67 ontrol mice and did not alter recruitment of intraepithelial leukocytes to esophageal tissues of IKKb

68 ultured IECs resulted in dramatic defects in intraepithelial localization and replication as well as

69 st selection of TCRalphabeta(+)CD8alphaalpha intraepithelial lymphocyte (IEL) progenitors (IELps), ev

70 D4(+) T helper functions and induction of an intraepithelial lymphocyte (IEL) program that included e

71 e reported that the pathogens induce a rapid intraepithelial lymphocyte (IEL) response important for

72 We reveal a local intestinal intraepithelial lymphocyte (IEL)-GLP-1 receptor (GLP-1R)

73 umed oats, 0.24; 95% CI, 0.01-4.8; P = .35), intraepithelial lymphocyte counts (standardized mean dif

74 tween groups, morphologic changes and CD3(+) intraepithelial lymphocyte counts differed significantly

75 ased intraepithelial lymphocytes, markers of intraepithelial lymphocyte cytotoxicity, gliadin-specifi

76 y stage NSCLC patient survival and increased intraepithelial lymphocyte infiltration.

77 ration and cytokine secretion in the spleen, intraepithelial lymphocyte inflammatory cytokines, and i

78 eta(+)CD4(-)CD8alpha(+)CD8beta(-) intestinal intraepithelial lymphocytes (CD8alphaalpha IELs) are an

79 tains CD4(+)CD8alphaalpha(+) double-positive intraepithelial lymphocytes (DP IELs), which originate f

80 In this context, intestinal intraepithelial lymphocytes (IEL) compose a large, highl

81 eaks, intervillous spaces, and the number of intraepithelial lymphocytes (IEL) were measured before a

82 ion of T cell receptor gammadelta-expressing intraepithelial lymphocytes (IEL), but these changes wer

83 The number of intraepithelial lymphocytes (IELs) and immune phenotypes

84 Intestinal intraepithelial lymphocytes (IELs) are a large and diver

85 Intestinal intraepithelial lymphocytes (IELs) are located at the cr

86 e of an enlarged clonal population of innate intraepithelial lymphocytes (IELs) lacking classical B-,

87 Intraepithelial lymphocytes (IELs) play an important rol

88 lial cells (ECs) is a population of resident intraepithelial lymphocytes (IELs) that provide host-pro

89 such as TCRalphabeta((+))CD8alphaalpha((+)) intraepithelial lymphocytes (IELs), require full-agonist

90 o recycling into intestinal CD4(-)CD8beta(-) intraepithelial lymphocytes (iIELs).

91 cell receptor alphabeta(+) CD4(-)CD8beta(-) intraepithelial lymphocytes (unconventional iIELs), a ma

92 In the ileum, the proportion of intraepithelial lymphocytes and goblet cells reduced, an

93 d with excess interferon-gamma production by intraepithelial lymphocytes and Myd88 activity.

94 Immunohistochemical studies of the intraepithelial lymphocytes and PCR amplification reveal

95 2.0 afterward; P = .0007; density of CD3(+) intraepithelial lymphocytes changed from 61 to 91 cells/

96 but not in the maintenance of CD8alphaalpha intraepithelial lymphocytes in the intestine.

97 CD8alphaalpha TCRalphabeta(+) intestinal intraepithelial lymphocytes play a critical role in prom

98 of intestinal alphabeta(+) and gammadelta(+) intraepithelial lymphocytes purified from germ-free mice

99 Intraepithelial lymphocytes that express the gammadelta

100 In the epithelium, interleukin-15 activates intraepithelial lymphocytes that promote destruction of

101 response and participate in the licensing of intraepithelial lymphocytes to kill intestinal epithelia

102 illus height to crypt depth and densities of intraepithelial lymphocytes were the primary end points.

103 , CD8alphaalphaTCRalphabeta small intestinal intraepithelial lymphocytes, and innate memory phenotype

104 , CD8alphaalphaTCRalphabeta small intestinal intraepithelial lymphocytes, and innate memory phenotype

105 ce within the intestine through retention of intraepithelial lymphocytes, functional redistribution o

106 Germ-free mice developed increased intraepithelial lymphocytes, markers of intraepithelial

107 villous height:crypt depth ratio, numbers of intraepithelial lymphocytes, or serologic markers of cel

108 Secondary end points included numbers of intraepithelial lymphocytes, serology test results (for

109 d Mucida discuss development and function of intraepithelial lymphocytes, which are found within the

110 Is, biopsies showed significant increases in intraepithelial lymphocytes, which were predominantly T

111 FD promoted a decreased in the proportion of intraepithelial lymphocytes.

112 is spatially matched by Nkrp1g on subsets of intraepithelial lymphocytes.

113 Intraepithelial macrophage projections, efficient phagoc

114 IL-9(+) ILC2 population, and an increase in intraepithelial mast cell numbers in the lung.

115 it does not distinguish between conjunctival intraepithelial melanin overproduction ("hyperpigmentati

116 Intraepithelial melanocytic proliferation without atypia

117 It is recommended that "intraepithelial melanocytic proliferation" be adopted fo

118 nin overproduction ("hyperpigmentation") and intraepithelial melanocytic proliferation.

119 In mice, intraepithelial migration to epithelial cells in contact

120 all skin development by selectively deleting intraepithelial mtDNA in mice by ablating a key maintena

121 High-grade anal intraepithelial neoplasia (AIN) is present in many human

122 t the long-term yield of high-grade cervical intraepithelial neoplasia (CIN) and the influence on bio

123 re defined as women classified with cervical intraepithelial neoplasia (CIN) grade 2+ (CIN2+) (n = 10

124 istory and histologically confirmed cervical intraepithelial neoplasia (CIN) in 2.5 years after the b

125 enic human papillomaviruses (HPVs), cervical intraepithelial neoplasia (CIN) is common, and current t

126 ous intraepithelial lesion (SIL) or cervical intraepithelial neoplasia (CIN) prevalence, incidence, p

127 To determine the population-based cervical intraepithelial neoplasia (CIN) trends when adjusting fo

128 Comparison of conjunctival intraepithelial neoplasia (CIN) vs SCC revealed SCC with

129 specimens, including 38 normal, 52 cervical intraepithelial neoplasia (CIN), and 68 cervical cancer

130 ated STAT3 increased from low-grade cervical intraepithelial neoplasia (CIN1) to precancerous CIN3 le

131 nning normalcy, increasingly severe cervical intraepithelial neoplasia (CIN1- CIN3), and cervical can

132 HC2 for the detection of high-grade cervical intraepithelial neoplasia (CIN2+) in a total of 8,610 ce

133 sts for hrHPV and HPV 16/18 to find cervical intraepithelial neoplasia (grade >/=2 [CIN2+] or grade >

134 sts for hrHPV and HPV 16/18 to find cervical intraepithelial neoplasia (grade >/=2 [CIN2+] or grade >

135 (MSM) who have a history of high-grade anal intraepithelial neoplasia (HGAIN) was associated with a

136 High-grade prostatic intraepithelial neoplasia (HGPIN) is considered a precur

137 e, Pten deletion induces high-grade prostate intraepithelial neoplasia (HGPIN).

138 uman prostate cancer and high-grade prostate intraepithelial neoplasia (HGPIN).

139 l transgenic mice developed murine prostatic intraepithelial neoplasia (mPIN) and prostatic adenocarc

140 tive stroma activation surrounding prostatic intraepithelial neoplasia (mPIN) lesions found both in i

141 ) in mice harboring oncogene-driven prostate intraepithelial neoplasia (mPIN).

142 stem (CNS) occurs as early as the pancreatic intraepithelial neoplasia (PanIN) 2 stage.

143 ), and KC(iMist1) mouse models of pancreatic intraepithelial neoplasia (PanIN) and analyzed by confoc

144 hat underwent ADM can progress to pancreatic intraepithelial neoplasia (PanIN) and eventually pancrea

145 A) develops predominantly through pancreatic intraepithelial neoplasia (PanIN) and intraductal papill

146 velopment and is induced in mouse pancreatic intraepithelial neoplasia (PanIN) and pancreatic ductal

147 ce of oncogenic KRAS, accelerates pancreatic intraepithelial neoplasia (PanIN) formation and the deve

148 ates acinar-to-ductal metaplasia, pancreatic intraepithelial neoplasia (PanIN) formation, and PanIN p

149 We previously demonstrated that pancreatic intraepithelial neoplasia (PanIN) formation, which prece

150 progressively develop high-grade pancreatic intraepithelial neoplasia (PanIN) lesions and neoplasia

151 transition from early to advanced pancreatic intraepithelial neoplasia (PanIN) lesions, we assessed w

152 to-ductal metaplasia and in early pancreatic intraepithelial neoplasia (PanIN) lesions.

153 ed and analyzed for inflammation, pancreatic intraepithelial neoplasia (PanIN), and PDAC.

154 C and its preinvasive precursors, pancreatic intraepithelial neoplasia (PanIN), arise via reprogrammi

155 ys, methylation analysis of early pancreatic intraepithelial neoplasia (PanIN), mouse models for PDAC

156 scin deficiency on development of pancreatic intraepithelial neoplasia (PanIn), PDAC, and metastasis.

157 n is expressed in human and mouse pancreatic intraepithelial neoplasia (PanIN), suggesting that N-cad

158 of PDA and its precursor lesion, pancreatic intraepithelial neoplasia (PanIN), we examined the effec

159 Using a murine model of pancreatic intraepithelial neoplasia (PanIN), we found that Kras(G1

160 , thus resisting the formation of pancreatic intraepithelial neoplasia (PanIN)-derived PDA.

161 ing initiation and development of pancreatic intraepithelial neoplasia (PanIN).

162 the formation and maintenance of pancreatic intraepithelial neoplasia (PanINs) in p48Cre; TetO-KrasG

163 iation and expansion of low-grade pancreatic intraepithelial neoplasia (PanINs), likely through diffe

164 titute hallmark features of human pancreatic intraepithelial neoplasia (PanINs), the precursor to pan

165 sufficient to induce formation of pancreatic intraepithelial neoplasia (PanINs)-a precursor of PDAC.

166 tubular complexes (TC) and early pancreatic intraepithelial neoplasia (PanINs).

167 EGLs) in men, including condyloma and penile intraepithelial neoplasia (PeIN).

168 s in wild-type mice rarely induced prostatic intraepithelial neoplasia (PIN) in dorsal prostates (one

169 used tumors in multiple organs and prostatic intraepithelial neoplasia (PIN) in mice.

170 Further, prostatic intraepithelial neoplasia (PIN) progressed to carcinoma

171 d loss of Akap12 and Rb results in prostatic intraepithelial neoplasia (PIN) that fails to progress t

172 sed the prevalence and severity of prostatic intraepithelial neoplasia (PIN), a premalignant lesion.

173 controls, and eventually developed prostatic intraepithelial neoplasia (PIN).

174 n paraffin-embedded VSCC and adjacent vulvar intraepithelial neoplasia (VIN) and VLS specimens, in ca

175 n of oncogenic KRAS, premalignant pancreatic intraepithelial neoplasia 1 (PanIN1) lesions rarely beco

176 Development of cervical intraepithelial neoplasia 2/3 was rare in women with red

177 ening algorithm found more disease (cervical intraepithelial neoplasia 3 or worse [CIN3+]) and also f

178 ly increased with disease severity (cervical intraepithelial neoplasia [CIN] 3, 17.9% [+/-7.2] vs CIN

179 enign prostatic hyperplasia [BPH], prostatic intraepithelial neoplasia [PIN], inflammation, and atrop

180 s to surgery for female patients with vulval intraepithelial neoplasia after exclusion of occult inva

181 ients, including 11 low-grade, 14 high-grade intraepithelial neoplasia and 12 invasive carcinoma in 3

182 normal mammary epithelium, developed ductal intraepithelial neoplasia and DCIS, and progressed to in

183 (Fl/Fl)) failed to progress beyond prostatic intraepithelial neoplasia and did not harbor genomic CNA

184 es local conservative treatment for cervical intraepithelial neoplasia and early invasive cervical ca

185 diminished SC chemoattraction to pancreatic intraepithelial neoplasia and increased abdominal hypers

186 low but increases significantly in cervical intraepithelial neoplasia and invasive squamous cervical

187 that Olfm4-knockout mice developed prostatic intraepithelial neoplasia and prostatic adenocarcinoma.

188 l, leading to early onset of mouse prostatic intraepithelial neoplasia and the progression of prostat

189 , safe, and feasible for treatment of vulval intraepithelial neoplasia and warrant further investigat

190 1 induced histological features of prostatic intraepithelial neoplasia at 7 months of age; these feat

191 ce exhibited metaplasia-associated prostatic intraepithelial neoplasia at a low frequency.

192 diagnosed cytologically; 1198 with cervical intraepithelial neoplasia grade 1 (CIN1), 456 with CIN2,

193 nst 6-month persistent infection or cervical intraepithelial neoplasia grade 1 or greater (CIN1+) ass

194 nst 6-month persistent infection or cervical intraepithelial neoplasia grade 1 or higher (CIN1+) asso

195 , clinical performance in detecting cervical intraepithelial neoplasia grade 2 (CIN2) or more severe

196 ic diagnosis of controls (less than cervical intraepithelial neoplasia grade 2 [<CIN2]) or cases (cer

197 nce of high-grade cervical disease (cervical intraepithelial neoplasia grade 2 or 3, adenocarcinoma i

198 Cumulative risks of cervical intraepithelial neoplasia grade 2 or greater (CIN-2+; th

199 the Xpert HPV for the detection of cervical intraepithelial neoplasia grade 2 or higher (CIN2+) and

200 eoplasia grade 2 [<CIN2]) or cases (cervical intraepithelial neoplasia grade 2 or higher [CIN2+]) for

201 des 2/3 and adenocarcinoma in situ (cervical intraepithelial neoplasia grade 2 or higher [CIN2+]) in

202 The sensitivity of Xpert for cervical intraepithelial neoplasia grade 2 or more severe diagnos

203 n have used the disease endpoint of cervical intraepithelial neoplasia grade 2 or worse (CIN2+).

204 ce in vaccine efficacy (VE) against cervical intraepithelial neoplasia grade 2 or worse in HPV-naive

205 ICIA criteria, VE estimates against cervical intraepithelial neoplasia grade 2 or worse, regardless o

206 nclarity assay for the detection of cervical intraepithelial neoplasia grade 2+ (CIN2+) and CIN3+ was

207 Both assays detected >/=91.7% of cervical intraepithelial neoplasia grade 2+ (CIN2+) lesions.

208 result, we identified 90 women with cervical intraepithelial neoplasia grade 2+ (CIN2+), including 43

209 lastic lesions and invasive cancer (cervical intraepithelial neoplasia grade 2+ [CIN2+]) compared to

210 low specificities for the detection of anal intraepithelial neoplasia grade 2/3 (AIN2/3) in this pop

211 uamous intraepithelial lesions (ie, cervical intraepithelial neoplasia grade 2/3 [CIN 2/3]) and (2) i

212 s from patients with HPV-associated cervical intraepithelial neoplasia grade 2/3 and murine skin disp

213 vulvar cancer), and vaginal disease (vaginal intraepithelial neoplasia grade 2/3, vaginal cancer) rel

214 cervical carcinoma), vulvar disease (vulvar intraepithelial neoplasia grade 2/3, vulvar cancer), and

215 alignancies in women diagnosed with cervical intraepithelial neoplasia grade 3 (CIN3).

216 igibility criteria were biopsy-proven vulval intraepithelial neoplasia grade 3 and at least one lesio

217 aseline specimens from 482 cases of cervical intraepithelial neoplasia grade 3 or cancer (CIN3+) and

218 Similar results were observed for cervical intraepithelial neoplasia grade 3 or higher (CIN3+) (n =

219 The primary endpoint was cervical intraepithelial neoplasia grade 3 or more severe (CIN3+)

220 ancer, 6.68 (95% CI, 3.64 to 12.25) for anal intraepithelial neoplasia grade 3, 4.97 (95% CI, 3.26 to

221 er, 13.66 (93% CI, 9.69 to 19.25) for vulvar intraepithelial neoplasia grade 3, 86.08 (95% CI, 11.98

222 , 25.65 (95% CI, 10.50 to 62.69) for vaginal intraepithelial neoplasia grade 3, and 5.51 (95% CI, 1.2

223 gnificance or greater (ASCUS+), and cervical intraepithelial neoplasia grades 1/2 or greater (CIN1+,

224 1 (HPV31) DNA loads and the risk of cervical intraepithelial neoplasia grades 2 and 3 (CIN2-3) was ev

225 % CI = 37.9 to 68.3) for diagnosing cervical intraepithelial neoplasia grades 2/3 (CIN2/3) on histolo

226 implemented mandatory reporting of cervical intraepithelial neoplasia grades 2/3 and adenocarcinoma

227 D2A resulted in the development of prostatic intraepithelial neoplasia in mice, demonstrating that JM

228 g a significant increase in the frequency of intraepithelial neoplasia in patients who received a lip

229 ntly accelerates the initiation of prostatic intraepithelial neoplasia in this model.

230 cally attenuates the formation of pancreatic intraepithelial neoplasia induced by mutant Kras(G12D),

231 Prostatic intraepithelial neoplasia is a precursor to prostate can

232 Vulval intraepithelial neoplasia is a skin disorder affecting t

233 standard treatment for patients with vulval intraepithelial neoplasia is surgery, but this approach

234 ic introduction of an oncogene for prostatic intraepithelial neoplasia lesion development.

235 eficient mice exhibited widespread prostatic intraepithelial neoplasia lesions in all prostatic lobes

236 ce and the replicative activity of prostatic intraepithelial neoplasia lesions in the dorsal prostate

237 l metaplasia (ADM)-a precursor of pancreatic intraepithelial neoplasia lesions that can progress to P

238 psy-proved squamous cell carcinoma or vulvar intraepithelial neoplasia occurred during follow-up in 0

239 of residual or recurrent high-grade cervical intraepithelial neoplasia of grade two or worse (CIN2+)

240 High-grade anal intraepithelial neoplasia or worse (HG-AIN+) was diagnos

241 nactivation of this GTPase at the pancreatic intraepithelial neoplasia stage promotes pancreatic tiss

242 PDAC tissues and in premalignant pancreatic intraepithelial neoplasia tissues isolated from Pdx-1-Cr

243 d cancer is not suspected, usual-type vulvar intraepithelial neoplasia treatment, including medical a

244 increased dramatically when only pancreatic intraepithelial neoplasia were apparent.

245 syndrome, clonal hematopoiesis, and cervical intraepithelial neoplasia which also serve as models for

246 at either noninvasive precursor (pancreatic intraepithelial neoplasia) or the PDAC stage led to inva

247 rly neoplastic lesions (high-grade prostatic intraepithelial neoplasia) with striking nuclear atypia

248 tal intraepithelial neoplasias (eg, cervical intraepithelial neoplasia).

249 eads to the formation of kidney cysts, renal intraepithelial neoplasia, and invasive papillary renal

250 ally accelerated the progression of prostate intraepithelial neoplasia, by promoting cell proliferati

251 t epithelial atypia (controls); conjunctival intraepithelial neoplasia, carcinoma in situ (CIS); and

252 normal prostate glands, high-grade prostatic intraepithelial neoplasia, invasive adenocarcinoma, or p

253 human pancreatic cancer cells and pancreatic intraepithelial neoplasia, the early lesion of pancreati

254 ntial reduction of ADM as well as pancreatic intraepithelial neoplasia-1 (PanIN-1), PanIN-2, and PanI

255 e without affecting hyperplasia or prostatic intraepithelial neoplasia.

256 yperplasia, or dysplastic lesions/pancreatic intraepithelial neoplasia.

257 fficient to induce hyperplasia and prostatic intraepithelial neoplasia.

258 ulation, leading to development of prostatic intraepithelial neoplasia.

259 arly as at the stage of high-grade prostatic intraepithelial neoplasia.

260 ve to surgery in female patients with vulval intraepithelial neoplasia.

261 and tolerable for treating usual-type vulvar intraepithelial neoplasia?

262 r the ability to predict high-grade cervical intraepithelial neoplasias (CIN2 or worse) in correspond

263 anogenital warts, oral warts, and anogenital intraepithelial neoplasias (eg, cervical intraepithelial

264 s the development of premalignant pancreatic intraepithelial neoplasias (PanINs) and cystic lesions i

265 cinar-to-ductal metaplasia (ADM), pancreatic intraepithelial neoplasias (PanINs) and ultimately pancr

266 as HPV DNA is detected in up to 90% of anal intraepithelial neoplasias and anal cancers.

267 and RAC1 were increased in human pancreatic intraepithelial neoplasias and PDAs compared with health

268 rom the transgenic mice regenerated prostate intraepithelial neoplasias and prostatic adenocarcinoma

269 was upregulated in patients with pancreatic intraepithelial neoplasias grade 3 and PDAC lesions rela

270 reater number and higher grade of pancreatic intraepithelial neoplasias than KC mice, and 1 mouse dev

271 (2 benign papillomas, 2 grade 2 conjunctival intraepithelial neoplasias, 7 in situ squamous carcinoma

272 decreased formation of high-grade pancreatic intraepithelial neoplasias, and accelerated development

273 y analyzed for formation of IPMN, pancreatic intraepithelial neoplasias, and PDAC, in addition to pro

274 nic KRAS in both the formation of pancreatic intraepithelial neoplasias, the most common precursor le

275 d acinar-to-ductal metaplasia and pancreatic intraepithelial neoplasias, which rapidly progressed to

276 is an essential component of the pancreatic intraepithelial neoplasias-to-PDAC route in Kras(G12D)-d

277 pancreatic ducts, referred to as pancreatic intraepithelial neoplasias.

278 mice, but did not alter growth of pancreatic intraepithelial neoplasias.

279 yses of precursor lesions, termed pancreatic intraepithelial neoplasm (PanINs) lesions, makes two pre

280 as in pancreatic tissues, develop pancreatic intraepithelial neoplasms (PanIN) that progress to pancr

281 rous pancreatic lesions, known as pancreatic intraepithelial neoplasms (PanIN), and describe a unique

282 ary mucinous neoplasms or grade 3 pancreatic intraepithelial neoplasms).

283 g increases detection of high-grade cervical intraepithelial neoplastic lesions and invasive cancer (

284 Children with STRA had increased intraepithelial neutrophils, which positively correlated

285 Intraepithelial nonproliferative melanocytic pigmentatio

286 Ten sebaceous carcinomas (8 invasive, 2 intraepithelial only) were stained immunohistochemically

287 Eight cases displaying an intraepithelial (or pagetoid) component of spread also s

288 Regarding intraepithelial (or pagetoid) spread, androgen receptor

289 Invasive or intraepithelial ovarian/tubal/peritoneal neoplasms were

290 lasms (IPMN), 2 adenocarcinomas, 1 low-grade intraepithelial pancreatic neoplasia, and 1 case of poly

291 e downregulation of tbpAB and hmbR, while an intraepithelial replication defect was consistent with t

292 Invasive growth and intraepithelial spread were analyzed separately.

293 The cells found in intraepithelial spread were strongly EMA and p53 positiv

294 ose an alternative mechanical model based on intraepithelial stresses generated by differential tensi

295 Hence, intraepithelial T cell activation offers an overt means

296 phabeta double-negative (DN) TCRalphabeta(+) intraepithelial T cells, although numerous, have been gr

297 plex (MHC) restriction of DN TCRalphabeta(+) intraepithelial T cells.

298 Intraepithelial T lymphocyte cells (IEL) are the first i

299 nting the accumulation of CD8 T cells in the intraepithelial versus lamina propria compartment.

300 he ablated areas, which appeared to be small intraepithelial vesicles.