ライフサイエンスコーパス: intraerythrocytic

1 e proteins that are considered unique to the intraerythrocytic agent of Anaplasma marginale and the i

2 The intraerythrocytic apicomplexan Babesia microti, the prim

3 or Maurer's clefts (Pfsbp 1 or mAb LWL1) or intraerythrocytic asexual parasite proteins (PfEMP2 or H

4 mine N-methyltransferase that block parasite intraerythrocytic asexual replication and gametocyte dif

5 of dual activity antimalarials to block both intraerythrocytic asexual replication and gametocytogene

6 f severe and fatal malaria are caused by the intraerythrocytic asexual reproduction cycle of Plasmodi

7 A recent study reveals that the intraerythrocytic asexual reproduction cycle of Plasmodi

8 A newly identified intraerythrocytic Babesia-like organism, WA1, and its re

9 type A tularemia, we showed the presence of intraerythrocytic bacteria by double-immunofluorescence

10 This sexual-stage tubular intraerythrocytic compartment (STIC) is not recognized b

11 Some of the intraerythrocytic crystals in this syndrome are unusuall

12 lu-->Lys) present red blood cells (RBC) with intraerythrocytic crystals that form when hemoglobin (Hb

13 a mild clinical course, abundant circulating intraerythrocytic crystals, and increased folded red cel

14 RBC, which in turn enhanced the formation of intraerythrocytic crystals.

15 sphoantigens were released at the end of the intraerythrocytic cycle at the time of parasite egress.

16 to promote var gene transcription during the intraerythrocytic cycle in vitro.

17 l response of P. falciparum to T4 during the intraerythrocytic cycle of this parasite.

18 During the intraerythrocytic cycle, malaria parasites metabolize la

19 ring nuclear division towards the end of the intraerythrocytic cycle.

20 molog of aminopeptidase P during its asexual intraerythrocytic cycle.

21 We hypothesized elevated intraerythrocytic deoxyHb would limit resilience to oxid

22 Polymerization of intraerythrocytic deoxyhemoglobin S (HbS) is the primary

23 acting via conversion to NO by reaction with intraerythrocytic deoxyhemoglobin.

24 At the end of intraerythrocytic development (late schizogony), there w

25 viction of nucleosomes on strong TSSs during intraerythrocytic development and demonstrate that nucle

26 ological changes in the parasites during the intraerythrocytic development by applying the interpreta

27 exhibit a higher potency after two cycles of intraerythrocytic development compared to one.

28 Gene expression during the intraerythrocytic development cycle of the human malaria

29 ession through the first part of the asexual intraerythrocytic development cycle.

30 Plasmodium falciparum intraerythrocytic development is a complex process.

31 rum revealed that fenpropimorph inhibits the intraerythrocytic development of both chloroquine- and p

32 matters over the alterations induced by the intraerythrocytic development of P. falciparum.

33 mosis) is a tick-borne disease caused by the intraerythrocytic development of protozoa parasites from

34 of potentially hundreds of genes during the intraerythrocytic development of this important human pa

35 er to analyse the expression of genes during intraerythrocytic development, DNA microarrays were cons

36 During their intraerythrocytic development, malaria parasites export

37 During intraerythrocytic development, Plasmodium falciparum exp

38 2 genes are expressed in different stages of intraerythrocytic development.

39 rane and plays an essential role in parasite intraerythrocytic development.

40 s and membrane biogenesis during the asexual intraerythrocytic development.

41 characterizing the transcriptome of the 48 h intraerythrocytic developmental cycle (IDC) for two stra

42 The asexual intraerythrocytic developmental cycle (IDC) of Plasmodiu

43 stablished the P. vivax transcriptome of the Intraerythrocytic Developmental Cycle (IDC) of two clini

44 onal activity over the course of the 48-hour intraerythrocytic developmental cycle (IDC); however, th

45 s in mining the malaria transcriptome of the intraerythrocytic developmental cycle of P. falciparum.

46 ta collected at seven time points during the intraerythrocytic developmental cycle, we (i) detect nov

47 in the cytoplasm of P. falciparum during the intraerythrocytic developmental cycle.

48 Anaplasma marginale, an intraerythrocytic ehrlichial pathogen of cattle, establi

49 he extracellular Trypanosoma brucei, unusual intraerythrocytic Endotrypanum spp., phytoparasitic Phyt

50 of an in vitro screening assay targeting the intraerythrocytic form of the malaria parasite Plasmodiu

51 be secreted shortly after activation of the intraerythrocytic gametocyte, and during sporozoite migr

52 When mature intraerythrocytic gametocytes are taken up in a blood me

53 One cyclic biphenyl ether compound inhibited intraerythrocytic growth of P. falciparum with an IC50 o

54 Intraerythrocytic growth of the human malaria parasite P

55 During intraerythrocytic growth, the parasite expresses protein

56 is prolonged from one to two generations of intraerythrocytic growth, with AZ producing 50% inhibiti

57 gesting that PfMYST is essential for asexual intraerythrocytic growth.

58 Here, we analyzed intraerythrocytic Hb, a protein that operates at the org

59 , we quantify the volume of the DV for live, intraerythrocytic HB3 (CQS), Dd2 (CQR via drug selection

60 our knowledge, to capture a temporal view of intraerythrocytic HbC phase separation, crystal formatio

61 The reaction rate between nitric oxide and intraerythrocytic hemoglobin plays a major role in nitri

62 Babesia spp. are tick-borne, intraerythrocytic hemoparasites that use antigenic varia

63 een recognized to play a central role during intraerythrocytic infection by Plasmodium parasites, the

64 s is only part of the story, as the P. vivax intraerythrocytic life cycle is complex.

65 During the intraerythrocytic life cycle of P. falciparum, a subset

66 doplasmic reticulum expressed throughout the intraerythrocytic life cycle of the parasite but induced

67 rrested parasite growth at all stages of the intraerythrocytic life cycle.

68 ose, and GDP-fucose in Plasmodium falciparum intraerythrocytic life stages.

69 ozoite egress near the end of the parasite's intraerythrocytic lifecycle.

70 etween the host erythrocyte membrane and the intraerythrocytic malaria parasite by demonstrating for

71 We hypothesise that intraerythrocytic malaria parasite metabolism is not mer

72 Intraerythrocytic malaria parasites can obtain nearly th

73 t In(III) (R)-ENBPI metallo-complexes killed intraerythrocytic malaria parasites in a stage-specific

74 Hemoglobin degradation in intraerythrocytic malaria parasites is a vast process th

75 Intraerythrocytic malaria parasites replicate by the pro

76 Intraerythrocytic malaria parasites send hundreds of eff

77 Intraerythrocytic malaria parasites use host hemoglobin

78 e blood, including platelets, which can kill intraerythrocytic malaria parasites.

79 mportant substrate for lipid biosynthesis of intraerythrocytic malarial parasites.

80 -dimensional (3D) versus time data for live, intraerythrocytic malarial parasites.

81 e of extracellular nutrient solutes, and (3) intraerythrocytic membranes transport a parasite-encoded

82 a target for antimalarial drug design as the intraerythrocytic merozoite lifestage of P. falciparum i

83 sed from an individual schizont, termed the "intraerythrocytic multiplication factor" (IMF).

84 at hemoglobinopathic erythrocytes reduce the intraerythrocytic multiplication of P. falciparum, poten

85 stem cell transplantation revealed numerous intraerythrocytic organisms typical of the genus Babesia

86 the characterization of the carbohydrates in intraerythrocytic P. falciparum proteins and provides an

87 cine is withdrawn from the culture medium of intraerythrocytic P. falciparum, the parasite slows its

88 n reductase is essential for the survival of intraerythrocytic P. falciparum.

89 ental stage-specific biosynthesis of GPIs by intraerythrocytic P. falciparum.

90 ed to the digestive vacuolar membrane of the intraerythrocytic parasite and may function as a transpo

91 tle is known about interactions between this intraerythrocytic parasite and the macrophages of its bo

92 tric assessment and mathematical modeling of intraerythrocytic parasite development revealed an unexp

93 ted beta-hematin formation in vitro, delayed intraerythrocytic parasite development with apparent inh

94 analyzed its function and expression during intraerythrocytic parasite development.

95 The intraerythrocytic parasite itself exerts tight control o

96 identified ion channel on the surface of the intraerythrocytic parasite may provide direct access to

97 Babesia bovis, an intraerythrocytic parasite of cattle, is sequestered in

98 Infection with this organism, an intraerythrocytic parasite of the phylum Apicomplexa, ca

99 Babesia microti, a tickborne intraerythrocytic parasite that can be transmitted by me

100 Babesiosis, usually caused by the intraerythrocytic parasite, Babesia microti and transmit

101 Babesia microti, a zoonotic intraerythrocytic parasite, is the primary etiological a

102 c function essential to the survival of this intraerythrocytic parasite.

103 inositol-polyphosphate production in intact intraerythrocytic parasite.

104 on in response to the metabolic needs of the intraerythrocytic parasite.

105 of mechanisms, light microscopy showed that intraerythrocytic parasites develop slowly in HbF erythr

106 nificantly different from those expressed by intraerythrocytic parasites from the mammalian host.

107 eir relative contribution to the survival of intraerythrocytic parasites might be.

108 Accordingly, intraerythrocytic parasites scavenged radiolabelled lipo

109 Using live, synchronized intraerythrocytic parasites under continuous perfusion,

110 s widespread protein and lipid damage inside intraerythrocytic parasites, necessitating macromolecule

111 tentially life-threatening disease caused by intraerythrocytic parasites, which usually are tickborne

112 nd in the digestive vacuole (DV) membrane of intraerythrocytic parasites.

113 t in two subcellular compartments in asexual intraerythrocytic parasites; that is, the food vacuole,

114 both the trophozoite and merozoite stages of intraerythrocytic parasitism.

115 asite Plasmodium falciparum replicates in an intraerythrocytic parasitophorous vacuole (PV).

116 The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV).

117 e Plasmodium falciparum replicates within an intraerythrocytic parasitophorous vacuole (PV).

118 The parasite divides within an intraerythrocytic parasitophorous vacuole until rupture

119 protozoan parasite that replicates within an intraerythrocytic parasitophorous vacuole.

120 Our results reveal a novel intraerythrocytic phase during F. tularensis infection.

121 During the intraerythrocytic phase of the life cycle, malaria paras

122 s by glycosylphosphatidylinositols (GPIs) of intraerythrocytic Plasmodium falciparum is believed to c

123 aging of hemozoin within live, synchronized, intraerythrocytic Plasmodium falciparum malarial parasit

124 cteria, two mammalian cancer cell lines, and intraerythrocytic Plasmodium falciparum, which they were

125 me released during hemoglobin proteolysis in intraerythrocytic Plasmodium falciparum.

126 s is important for hemoglobin degradation in intraerythrocytic Plasmodium parasites.

127 ays an important role in the pathogenesis of intraerythrocytic Plasmodium parasites.

128 Because hemoglobin (Hb) is the most abundant intraerythrocytic protein and reacts rapidly with NO, th

129 osis, a tickborne zoonotic disease caused by intraerythrocytic protozoa of the genus babesia, is char

130 alth problem in humans, is caused by related intraerythrocytic protozoa with a similar pathogenesis a

131 B. bovis, an intraerythrocytic protozoal parasite, establishes chroni

132 Babesia microti, a tick-transmitted, intraerythrocytic protozoan parasite circulating mainly

133 Bovine anaplasmosis caused by the intraerythrocytic rickettsial pathogen Anaplasma margina

134 Anaplasma marginale is an intraerythrocytic rickettsial pathogen of cattle in whic

135 re the activity of existing antimalarials on intraerythrocytic sexual stage gametocytes and identify

136 xamined the expression of STEVOR proteins in intraerythrocytic sexual stages, gametocytes, and extrac

137 Here we show that (1) both cell-free and intraerythrocytic SNO-Hb (SNO-RBC) inhibit platelet aggr

138 ere a transcriptome-wide characterization of intraerythrocytic splicing events, as captured by RNA-Se

139 During the intraerythrocytic stage of infection, the malaria parasi

140 During the intraerythrocytic stage of Plasmodium falciparum's lifec

141 required for both a prolonged period of the intraerythrocytic stage of Plasmodium infection, as well

142 ia parasite Plasmodium falciparum during the intraerythrocytic stage of the parasite's lifecycle.

143 t the major carbohydrate modification in the intraerythrocytic stage P. falciparum proteins; 2) in co

144 anchors are crucial for the survival of the intraerythrocytic stage Plasmodium falciparum because of

145 e and extent of carbohydrate modification in intraerythrocytic stage Plasmodium falciparum proteins h

146 tols (GPIs) are the major glycoconjugates in intraerythrocytic stage Plasmodium falciparum.

147 lobin (Hb) as a major nutrient source in the intraerythrocytic stage, during which heme is converted

148 ies of gene expression throughout the entire intraerythrocytic stage.

149 althy RBCs and RBCs parasitized to different intraerythrocytic stages by the malaria-inducing parasit

150 Intraerythrocytic stages efficiently trigger Vgamma9Vdel

151 1o is fast acting and highly active against intraerythrocytic stages of chloroquine-sensitive and re

152 he growth of the parasite during the asexual intraerythrocytic stages of infection.

153 t pathway may contribute to the virulence of intraerythrocytic stages of malarial infection.

154 d synthase and lipoic acid protein ligase in intraerythrocytic stages of P. falciparum.

155 Our systematic experiments cover all intraerythrocytic stages of parasite development under p

156 Plasmodium-infected erythrocytes during all intraerythrocytic stages of parasite development.

157 Northern analysis of RNA from intraerythrocytic stages of the parasite demonstrates th

158 The intraerythrocytic stages of the protozoan parasite Plasm

159 s expressed as a long and a short version in intraerythrocytic stages.

160 ipoate scavenging is critical for Plasmodium intraerythrocytic survival.