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1 eracting residues between intermolecular and intramolecular.
3 kH/kD approximately 150, associated with an intramolecular 1,5-hydrogen atom transfer (1,5-HAT) in t
4 al cyclization path involving reprotonation, intramolecular 1,6 proton transfer, and concerted but as
6 ubsequent reduction to ammonia is enabled by intramolecular 2H(+)/2e(-) proton-coupled electron trans
9 ing alpha,beta-unsaturated esters toward the intramolecular addition of a pendant guanidinyl nucleoph
11 with each subjected to a palladium-catalyzed intramolecular Alder-ene (IMAE) reaction, thus producing
16 led to successive gamma-C(sp(3))-H arylation/intramolecular amidation and the construction of both C-
18 igate the arylation and successive arylation/intramolecular amidation of the gamma-C(sp(3))-H bonds.
19 atalyzed C-H bond amidation proceeding by an intramolecular amide transfer in N-phenoxyacetamide deri
20 ments indicate HAT is rate-limiting, whereas intramolecular amination is product- and stereo-determin
22 iomyopathy-causing mutations that affect the intramolecular and intermolecular interactions controlli
23 to the parental strain, suggesting that both intramolecular and intermolecular PorB interactions cont
24 g of the scaffold to form functional RNAs is intramolecular and is therefore robust and concentration
26 oligomers in physiological solutions have an intramolecular antiparallel configuration that is distin
27 ics from the phosphoserine group disrupt its intramolecular association, resulting in poorer autoinhi
31 the E3 ligase, SMURF2, is antagonized by an intramolecular, autoinhibitory interaction between its C
32 les with activated aziridines followed by an intramolecular aza-Michael reaction in a domino fashion.
33 ng of the role that flexible linkers play in intramolecular binding and provides valuable information
34 the presence of the flexible linker and the intramolecular binding motif by assuming the flexible li
36 ng to our calculations and measurements, the intramolecular binding motif reduces the apparent affini
38 son now identify a novel mechanism of DENND3 intramolecular binding that is regulated by the phosphor
39 h, in unstressed conditions, is inhibited by intramolecular binding to the Vms1 leucine-rich sequence
40 nide insertion under aerobic conditions with intramolecular bis-amine nucleophiles has been developed
41 icient synthon strategy involving sequential intramolecular bisboronate homocoupling and reductive ar
42 ed to alkenes through a urea linkage undergo intramolecular C-alkenylation on treatment with base by
44 cterium tuberculosis that catalyzes a single intramolecular C-C cross-linking reaction in the biosynt
45 rting its influence on consecutive inter- or intramolecular C-C or C-X bond-forming events via result
47 lphosphido) complex (1) undergoes reversible intramolecular C-H bond activation enabling the catalyti
48 place of the heme catalyze enantioselective intramolecular C-H bond amination reactions of sulfonyl
49 ses directly unprotected secondary amines by intramolecular C-N bond forming dearomatization or aryl
51 version and stereocontrol (up to 95:5 er) in intramolecular carbolithiation reactions, outperforming
53 in the other ring, both direct and crossover intramolecular cation-nucleophile reactions occur to giv
54 ral peptides and a protein with an inter- or intramolecular cation-pi interaction between tryptophan
55 s (subtilases, SBTs) serve dual functions as intramolecular chaperones that are required for enzyme f
60 ch as photo-induced electron transfer (PET), intramolecular charge transfer (ICT), aggregation-induce
61 ylidene-expanded TCBD unit results in strong intramolecular charge transfer and lowering of the LUMO
62 ed solvatofluorochromic effects arising from intramolecular charge transfer, moderate fluorescence qu
65 analysis confirms these materials undergo an intramolecular charge-transfer event upon photoexcitatio
68 the presence of Ca(2+) and Mg(2+) inhibited intramolecular charge-transfer within photoexcited NOM,
69 , intermolecular (allosteric) cooperativity, intramolecular (chelate) cooperativity and interannular
70 tead undergoing preferential substitution in intramolecular competition with more electron-rich rings
71 sence of LDA, followed by in situ alkylation-intramolecular condensation of the resulting enethiolate
72 more compact conformation, with FliGC making intramolecular contact with FliGM of the same subunit.
73 nteraction can further be facilitated by the intramolecular contacts between different extracellular
74 and biochemistry, we show that TA increases intramolecular contacts within the LBD to drive affinity
75 s of reactivity is quite powerful in a fully intramolecular context and, when terminated by a stereos
77 on has some unusual features that include an intramolecular coupled hydrogenation-dehydrogenation pro
78 at the individual plasmonic molecule level, intramolecular coupling of acoustic modes, mediated by t
79 is demonstrated by a high-yielding fivefold intramolecular coupling to form a helical ZrPAH with 16
81 r lysines drives the formation of inter- and intramolecular cross-linkages, a process critical for th
82 reover, we found that DCCD mediates discrete intramolecular cross-links of E. coli TatC involving bot
83 ar recognition and a dynamic nature to their intramolecular crosslinkers to form polymer films, and a
84 moieties along the backbone allowed for the intramolecular crosslinking of single chains via the add
86 uickly (30-45 min) via in situ formation and intramolecular cyclization of alkyl 2-[(2-alkoxybuta-2,3
89 the aminooxy functionality and a dehydrative intramolecular cyclization under mild conditions to form
93 with B(C6 F5 )3 enabled the first catalytic intramolecular cyclizations of carboxylic acid substrate
96 ent diastereoselectivity was observed in the intramolecular cycloaddition reaction producing 5 to 7-m
97 irst time as dipolarophiles in a 1,3-dipolar intramolecular cycloaddition reaction, leading to the co
99 We propose novel stereo- and regiospecific intramolecular cycloadditions, under tight functional gr
100 catalyzes amide bond formation, and then the intramolecular cyclodehydration between a Cys, Ser, or T
102 lds and better efficiencies are observed for intramolecular diboronic ester homocouplings when direct
103 derivative and (2) a highly stereoselective intramolecular Diels-Alder (IMDA) reaction of the campha
104 ollowed by three pericyclic transformations: intramolecular Diels-Alder and hetero-Diels-Alder reacti
106 e naturally existing enzymatic examples (the intramolecular Diels-Alder reaction, and the Cope and th
107 ts at thermal and several Lewis acid induced intramolecular Diels-Alder reactions remained fruitless,
110 ol-3-ium bromides undergo a copper-catalyzed intramolecular direct C arylation under mild conditions
111 , and air-stable 1 catalyzes the challenging intramolecular direct C(sp(3))-H amination of unactivate
112 pyrrolyl-1,2,4-triazoles via copper-mediated intramolecular direct C-arylation of 1,2,4-triazoles was
113 phase properly, the importance of inter- and intramolecular dispersion in solution remains yet to be
114 tion, showing that attenuation of inter- and intramolecular dispersive interaction by solvent is larg
116 activity of bGP through the formation of an intramolecular disulfide bond (Cys(318)-Cys(326)), known
118 ng six conserved cysteine residues that form intramolecular disulfide bonds, are a family of mucin-as
119 Preformed compartments generally rely on intramolecular disulfide bridging to maintain conformati
120 ethered within the NAD(+)-binding site by an intramolecular disulfide in the oxidized state dissociat
126 med that these reactions mainly proceeded by intramolecular electron transfer (ET) between the triple
127 We obtain a lower limit on the rate of this intramolecular electron transfer (IET) that is >10(4) fa
131 ism of Pd-catalyzed C-CN bond activation and intramolecular enantioselective alkene cyanoamidation.
132 we identified an enzyme that can perform an intramolecular enantioselective hydroalkoxylation reacti
134 /2) iron complex ((Ar)L)Fe which features an intramolecular eta(6)-arene interaction and can be utili
136 r to spectroscopically evaluate in-depth the intramolecular exchange interactions in this type of pro
137 with SnI2 than FA+ ions will facilitate the intramolecular exchange with FA+ ions, thereby enabling
139 s the first enzyme for which catalysis of an intramolecular [Formula: see text]-cycloaddition has bee
141 ed via a highly selective conjugate addition/intramolecular Friedel-Crafts acylation sequence to deli
143 des six C-C ring-closure steps that, through intramolecular Friedel-Crafts-type reactions, allow the
144 ociated with meiosis-specific DSBs fold into intramolecular G-quadruplex and i-motif structures, both
147 n of the bisallylic group, followed by rapid intramolecular H(*) transfer, yielding allylic radicals
148 s of four Gd complexes capable of forming an intramolecular H-bond to the coordinated water ligand, a
149 ulations supported the formation of a stable intramolecular H-bond, while alternative hypotheses that
150 nsight into the interplay between inter- and intramolecular H-bonded conformer topologies for the sam
151 ble bonds separating the recognition sites), intramolecular H-bonding is favored, and the folded stat
153 adverse steric interactions are removed when intramolecular H-bonds are formed and therefore provide
156 xy peroxy radical (C5H11O6.) must undergo an intramolecular H-shift with a net forward rate constant
157 as a base in DMF, followed by Pd(0)-mediated intramolecular Heck coupling in the presence of K2CO3 in
158 r complexity and employs an enantioselective intramolecular Heck reaction to set the absolute stereoc
159 have been developed via in situ or stepwise intramolecular heteroannulation of newly synthesized 4,5
160 Interestingly, the U3 and A6 bases form an intramolecular Hoogsteen base pair and directly contact
161 ing reaction to assemble the polyene, and an intramolecular Horner-Wadsworth-Emmons olefination to fo
162 synthesis include macrolactonization through intramolecular Horner-Wadsworth-Emmons olefination, Yama
163 of stereospecific transformations, including intramolecular Hosomi-Sakurai reactions, to set vicinal
166 mine esters undergo copper hydride-catalyzed intramolecular hydroamination with a high degree of regi
167 facile synthesis of amidyl radicals used in intramolecular hydroaminations to produce isoindolinones
169 readily mediates both enyne cyclization and intramolecular hydroarylation reactions, at room tempera
170 nary mechanistic hypothesis characterized by intramolecular hydrogen atom transfer, radical fluorinat
171 effects associated with the existence of an intramolecular hydrogen bond (CH...N) between the six-me
173 proximity, high ionic strength that promotes intramolecular hydrogen bond formation, and deformation
175 udies showed the presence of bifurcated weak intramolecular hydrogen bonding (F...HN) and N(+)...F(de
176 s toward the North-East sugar pucker, due to intramolecular hydrogen bonding and hyperconjugation eff
179 defluorination of fluorines that can undergo intramolecular hydrogen bonds that form 5-8-membered cyc
180 ironments underlines the competition between intramolecular hydrogen migration of peroxy radicals and
181 enerative peroxy radical formation following intramolecular hydrogen shifts-is known to be important
185 nosilylsilylene 1, which readily performs an intramolecular insertion into a C horizontal lineC bond
186 by which this phosphorylation regulates the intramolecular interaction between CAR's DBD and ligand-
187 osphomimetic mutation of Ser-561 promotes an intramolecular interaction between GK and the nearby Src
188 domain that overlaps with the known site of intramolecular interaction between the J domain and the
190 ese simulations pointed to a key role for an intramolecular interaction between the pseudopilin N-ter
192 Our results also demonstrate that, once this intramolecular interaction is released, the integrin-bou
194 odelling revealed that two mutations disrupt intramolecular interaction of PTEN and open its conforma
195 ation of GEF activity is achieved through an intramolecular interaction that is controlled by a key r
197 osphorylation destabilizes an autoregulatory intramolecular interaction within eIF2alpha; and (ii) th
199 n of Von Willebrand factor is accelerated by intramolecular interactions and increases GPIbalpha diss
200 backbones (fewer than five rotatable bonds), intramolecular interactions are not observed, and foldin
203 that RAF inhibitors induce the disruption of intramolecular interactions between the kinase domain an
205 results in a completely different network of intramolecular interactions between the SCCH and adenyla
207 no precedent in TCBD chemistry, results from intramolecular interactions in the excited state between
208 analyses demonstrate that these competitive intramolecular interactions negatively regulate Npm hist
210 zation sensitivity results from weakening of intramolecular interactions that maintain Env integrity.
211 insically disordered, yet utilizes transient intramolecular interactions with the DNA-recognition hel
213 220), forming a fuzzy complex via inter- and intramolecular interactions, mainly through hydrophobici
214 ely stabilize individual EGF repeats through intramolecular interactions, thereby regulating Notch tr
218 ns and to investigate the effect of distinct intramolecular motifs on xylan conformation and on the i
219 hereas linkage in the beta-position prevents intramolecular N...S interaction, resulting in a less pr
220 at the alpha-position allows both inter- and intramolecular N...S interaction, whereas linkage in the
223 yl-B(Naph(Br,R))2 (3a-c) are subjected to an intramolecular Ni-mediated Yamamoto reaction to close th
225 nium intermediate, followed by an asymmetric intramolecular nucleophilic addition to form chiral cycl
227 a-Haloalkylphosphine derivatives undergo the intramolecular nucleophilic substitution reaction upon t
230 collected samples, which is consistent with intramolecular oxidation of DOM moieties by (3)DOM*.
231 bearing a 2-keto or formyl group through the intramolecular oxidative aza-annulation of enynyl azides
232 nzo[b]furans via a regioselective 5-exo-trig intramolecular oxidative cyclization of ortho-cinnamyl p
233 rst time, that only E-enamides could undergo intramolecular oxidative cyclization under the optimized
236 nformed our choice to pursue and develop the intramolecular oxyacylation of alkenes via quinoline-dir
238 fective molarities (EM) for the formation of intramolecular phenol-amide H-bonds as a function of sol
243 tion is amine 4 that undergoes excited-state intramolecular proton transfer (ESIPT) in neat CH3CN whe
247 bind early in the catalytic cycle, allowing intramolecular proton-coupled electron transfer to lower
249 an effective metalloradical catalyst for the intramolecular radical aziridination of this type of car
250 sites and shine light on the preference for intramolecular rather than intermolecular recognition of
251 ogether in the center of C1 and an intricate intramolecular reaction mechanism for activation of C1r
252 (Cak1), and Y209 is autophosphorylated in an intramolecular reaction that requires the meiosis-specif
253 ternal heteroarenes proceeds faster than the intramolecular reaction, allowing the formation of 1,2-d
256 ered a mild and metal-free C-H sulfenylation/intramolecular rearrangement cascade reaction employing
258 s through a degradative, charge-neutralizing intramolecular rearrangement, leading to intracellular r
260 w approach that is based on the quantitative intramolecular reductive cyclization of an oligo(diyne)
261 in repeats of Trio, allowing them to relieve intramolecular repression of Trio GEF activity by the Tr
262 anscriptome identified thousands of putative intramolecular RG4s that readily assemble in vitro but s
264 since the tetravalent molecule can form two intramolecular rings with different "stabilities" due to
265 ne vapors caused a significant change in the intramolecular rotation, increasing the known activation
266 tructures of fluorophores to impart hindered intramolecular rotations, leading to desirable solid-sta
267 predicted physiological ionic strengths, the intramolecular searching ability of Pol beta is at least
268 f 7b showed that the molecule, due to strong intramolecular secondary Se...N interactions, is complet
271 haperone regulation via dynamic and specific intramolecular shielding of histone interaction sites.
272 ions stabilize the spirolactone and prevent intramolecular side reactions during chemical labeling,
276 l-molecule activation 1 allows access to the intramolecular silanone-borane 3 featuring a Si=O-->B in
281 In comparison, the loop residues and the intramolecular strand-strand interface have low hydratio
282 related substrates undergo copper-catalyzed intramolecular sulfamidation at the benzylic methylene t
283 method for the catalytic, enantioselective, intramolecular sulfenoamination of alkenes with aniline
285 ings when directly compared to the analogous intramolecular Suzuki-Miyaura cross-couplings or reducti
290 arbinyl cations, which undergo ring opening, intramolecular trapping by the neighboring ester group,
292 high water solubility, without any signs of intramolecular triple helix formation or fiber-fiber agg
293 ions favorable for H-DNA formation, a stable intramolecular triplex DNA structure predominated; where
295 N-deprotonated 1,2-azaborines followed by an intramolecular version of the boron deprotection reactio
297 lecular systems is often strongly coupled to intramolecular vibrations that can promote, suppress and
298 g the reaction coordinate reveals details of intramolecular vibronic coupling before a slower vibrati
300 (3))-H), the nature of the process involved (intramolecular with a directing group or intermolecular)
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