ライフサイエンスコーパス: intramuscular injection

1 vaccination method (ie, microneedle patch vs intramuscular injection).

2 mdx mouse and in four DMD patients by local intramuscular injection.

3 e vaccines were introduced into mice through intramuscular injection.

4 , 4 mg (n=20), or 8 mg (n=15) by needle-free intramuscular injection.

5 ction of vaccine or placebo, administered by intramuscular injection.

6 vaccine evoked bactericidal antibodies after intramuscular injection.

7 otor neurons from the periphery following an intramuscular injection.

8 the myocardium with less injury over direct intramuscular injection.

9 s similar to or better than that elicited by intramuscular injection.

10 implanted into female mouse hearts by direct intramuscular injection.

11 s in a mouse model following intrajugular or intramuscular injection.

12 od to deliver cells into the heart is direct intramuscular injection.

13 lipid A (MPL) and administered with alum by intramuscular injection.

14 istered to breast cancer patients by monthly intramuscular injection.

15 n cargo into spinal cord motor neurons after intramuscular injection.

16 ikely after intravenous injection than after intramuscular injection.

17 at higher levels than those by conventional intramuscular injection.

18 stable in solution and poorly absorbed after intramuscular injection.

19 nide-poisoned mice and rabbits when given by intramuscular injection.

20 r a drug that can be given quickly, e.g., by intramuscular injection.

21 ibodies at high concentrations from a single intramuscular injection.

22 nization to RVFV in addition to conventional intramuscular injection.

23 cle is preferred over the deltoid muscle for intramuscular injections.

24 ection of acidic saline compared with pH 7.2 intramuscular injections.

25 o-reporter expression in motor neurons after intramuscular injections.

26 owth hormone following intracardiac, yet not intramuscular, injection.

27 on and placebo were administered as a single intramuscular injection (1 ml) at weeks 0, 4, 8, and 20.

28 bumin or rhVEGF was administered by a single intramuscular injection (2 microg/kg body weight) to New

29 Following intramuscular injection, a TAP fragment encoding hepatit

30 ssion when compared to concentration matched intramuscular injections, a control condition in which c

31 h placebo (all p<0.0001) and were similar to intramuscular injection (all p>0.01).

32 ch, confers protection superior to that with intramuscular injection and enables potential dose-spari

33 pression of therapeutic levels of F.IX after intramuscular injection and is a feasible strategy for t

34 ne response to AAV capsid proteins following intramuscular injection and its impact on vector readmin

35 l culture, and two in vivo delivery methods (intramuscular injection and systemic intravenous injecti

36 determined the pathogenic mechanism linking intramuscular injections and provocation poliomyelitis.

37 ntly better than that seen with conventional intramuscular injection, and comparable to that observed

38 sport by spinal cord motor neurons following intramuscular injection, and exhibited both TTC- and IGF

39 79]) and pain (11 [44%] of 25 [24-65]) after intramuscular injection; and as tenderness (33 [66%] of

40 re <50 mm Hg received placebo or HGF-plasmid intramuscular injection as follows: 0.4 mg at days 0, 14

41 We delivered the vaccines by intramuscular injection as plasmid DNA without adjuvant

42 ts randomized to a MVA-5T4 group received an intramuscular injection at a dose of 1 x 109 50% tissue

43 edle patches were at least as immunogenic as intramuscular injection at the same dose, as demonstrate

44 mmunize mice in comparison with conventional intramuscular injection at the same dose.

45 dure, consisting of a series of percutaneous intramuscular injections at a single timepoint, was not

46 Compared with an intramuscular injection boost, mice receiving the MNP bo

47 radermal injections than among recipients of intramuscular injections, but such reactions were mild a

48 We then determined AZD8529 (.03-10 mg/kg, intramuscular injection) effects on intravenous nicotine

49 e-blind, randomized study, patients received intramuscular injections every 2 weeks of placebo or lon

50 1 or rabies vaccine (both 0.5 mL per dose by intramuscular injection), given once per month at 0, 1,

51 After a single intramuscular injection hematocrit values increased and

52 Intramuscular injection in arthritic mice of plasmid DNA

53 route has theoretical advantages over direct intramuscular injection in global cell dissemination int

54 unogenicity of Nanopatch immunisation versus intramuscular injection in rats, using monovalent and tr

55 Four weeks after intramuscular injection into mouse ischemic hindlimbs, g

56 d to the spinal cord and brainstem following intramuscular injection into the diaphragm of rats.

57 We found that intramuscular injection is always associated with a weak

58 ing of this inexpensive candidate vaccine by intramuscular injection is planned.

59 Recently, it has been reported that intramuscular injections may also increase the likelihoo

60 er, in contrast to mice treated with GDNF by intramuscular injection, mice receiving GDNF:TTC reveale

61 Compared to conventional intramuscular injection, microneedle vaccination resulte

62 eceived 600 micrograms vaccine or placebo by intramuscular injection monthly for 6 months then every

63 aking risperidone or paliperidone by regular intramuscular injection (n=8), and healthy comparison su

64 With intramuscular injection, no prolongation was found at th

65 to aerosolized anthrax spores, and a single intramuscular injection of 1 mg/kg of body weight fully

66 ne, when given to healthy adults as a single intramuscular injection of 1, 4, or 10 microg/serogroup,

67 We assessed the effects of a single intramuscular injection of 10 mg vitamin B-12 (which als

68 A single intramuscular injection of 100 micrograms pSK-GHRH DNA e

69 a prime-boost vaccination regime comprising intramuscular injection of 100mug CN54gp140+200mug R848

70 oporation at baseline and week 4 followed by intramuscular injection of 108 plaque forming units of M

71 f early syphilis support the use of a single intramuscular injection of 2.4 million U of benzathine p

72 Intramuscular injection of 3 doses of quadrivalent HPV v

73 All participants received intramuscular injection of 4 mg vaccine.

74 Following the intramuscular injection of 5% hypertonic saline, 49% of

75 After intramuscular injection of 5, 10, and 20 x 10(6) myoblas

76 kg during days 8 to 10 (group 4), and daily intramuscular injection of 5.0 mg of ceftiofur hydrochlo

77 Intramuscular injection of 6 mg/kg xylazine induced an i

78 Twenty-four hours after a single intramuscular injection of [3H]thymidine, labeled cells

79 myofibers were intensely blue following the intramuscular injection of a beta-galactosidase expressi

80 Intramuscular injection of a clostridial toxin preparati

81 disease in mice and hemophilic dogs through intramuscular injection of a recombinant adeno-associate

82 In this study, we demonstrate that a single intramuscular injection of a recombinant adeno-associate

83 We sought to determine whether intramuscular injection of a recombinant adeno-associate

84 Towards this objective, we show that intramuscular injection of a replication-incompetent, re

85 e side only of the spinal cord by unilateral intramuscular injection of a retrogradely transported fo

86 A single intramuscular injection of a self-replicating RNA immuno

87 ng a nonsense mutation, can be skipped after intramuscular injection of a specific 2'-O-methyl phosph

88 exaggerate the immune response induced after intramuscular injection of AAV serotype 2 vector.

89 s, we examined immune responses to FIX after intramuscular injection of AAV with simultaneous activat

90 y transferred into mice that had received an intramuscular injection of AAV-lacZ 10 days earlier.

91 ruitment and activation of DCs subsequent to intramuscular injection of AAV.

92 In addition, inhibiting myostatin using intramuscular injection of AAV1-follistatin ameliorates

93 ependent of the cAMP pathway by 1 week after intramuscular injection of acid.

94 Intramuscular injection of AdCA5 into the ischemic limb

95 enting HIF-1alpha levels in ischemic limb by intramuscular injection of AdCA5, an adenovirus encoding

96 nce to coagulation factor IX (FIX) by direct intramuscular injection of adeno-associated virus (AAV)-

97 When R333Q-hFIX mice were challenged by intramuscular injection of adeno-associated virus expres

98 We show that intramuscular injection of adeno-associated virus seroty

99 of recombinant adenoviruses, and boosted by intramuscular injection of adjuvanted F and G proteins,

100 ere is universal expert agreement that rapid intramuscular injection of adrenaline is life-saving and

101 naphylactic shock, which was relieved by the intramuscular injection of adrenaline.

102 toxin-neutralizing antibody titers than did intramuscular injection of alum-adsorbed rPA.

103 d toxicity, we initiated a clinical study of intramuscular injection of an AAV vector expressing huma

104 Recent studies have shown that intramuscular injection of an adeno-associated viral (AA

105 We performed intramuscular injection of an adeno-associated virus (AA

106 been supplemented for this growth factor via intramuscular injection of an adenoviral vector encoding

107 Intramuscular injection of an adenovirus encoding domina

108 Intramuscular injection of an inflammatory irritant, mus

109 Intramuscular injection of an unadjuvanted HIV-1 envelop

110 Preclinical studies provide evidence that intramuscular injection of autologous CD34+ cells improv

111 Intramuscular injection of BALB/c mice with a DNA plasmi

112 We show that intramuscular injection of BCG reduced by 76% (Odds rati

113 Subcutaneous or intramuscular injection of both conjugates elicited a 50

114 Intramuscular injection of Botox resulted in a significa

115 We prevented limb use by the intramuscular injection of botulinum toxin A into select

116 the final regression model, subcutaneous or intramuscular injection of BTH was the only behavior ass

117 enuates masseter hypersensitivity induced by intramuscular injection of capsaicin.

118 s medialis muscle were selectively killed by intramuscular injection of cholera toxin-conjugated sapo

119 Motoneurons were labeled by intramuscular injection of cholera toxin-horseradish per

120 ical signs of impaired cobalamin function, 1 intramuscular injection of cobalamin resulted in biochem

121 Direct intramuscular injection of compound RTC14 did not result

122 In two baboons studied, the intramuscular injection of CVF (0.25 mg/kg) was followed

123 A second intramuscular injection of CVF on day 14 was ineffective

124 Intramuscular injection of dexamethasone had a profound

125 They received a single 75-mg (3 mL) intramuscular injection of diclofenac (n = 27) or simila

126 One intramuscular injection of dMAb produced antibodies in v

127 Intramuscular injection of DNA plasmids produced a diffe

128 Intramuscular injection of DNA vaccines elicits potent h

129 Intramuscular injection of DTX caused cytopathology in m

130 Focal infection was induced in rats by an intramuscular injection of E. Coli in the right thigh.

131 randomly assigned to receive a single 0.5-mL intramuscular injection of either V710 vaccine, 60 mug (

132 s were randomly assigned to receive a single intramuscular injection of either vaccine or saline.

133 measure local blood flow at the site of the intramuscular injection of exotoxins from an invasive M-

134 were retrogradely labeled after percutaneous intramuscular injection of Fluorogold (FG) into the EAS.

135 were retrogradely labelled in adult rats by intramuscular injection of Fluorogold and examined with

136 As compared with an intramuscular injection of full-dose influenza vaccine,

137 atients were randomized to receive either an intramuscular injection of fulvestrant 250 mg once month

138 dministered DATS orally and/or given a local intramuscular injection of green fluorescent protein-lab

139 The Study to Assess the Safety of Intramuscular Injection of Hepatocyte Growth Factor Plas

140 hat modulating satellite cell quiescence via intramuscular injection of HGF increases the penetrance

141 Intramuscular injection of HGF plasmid was safe and well

142 A single intramuscular injection of IGF-1, but not PBS, markedly

143 e EGG recording was started 20 minutes after intramuscular injection of ketamine and azaperone (perio

144 normal human F.IX levels) can be reached by intramuscular injection of mice using a 2- to 4-fold low

145 Intramuscular injection of mice with an adeno-associated

146 ocytic sarcoma could be similarly induced by intramuscular injection of MLL-AF9 leukemia cells.

147 Intramuscular injection of MuLE viruses expressing oncog

148 1 or vehicle was administered for 3 weeks by intramuscular injection of murine ischemic hindlimbs.

149 red human TIMP-4 by electroporation-mediated intramuscular injection of naked DNA using the rat adjuv

150 y be cautiously interpreted to indicate that intramuscular injection of naked plasmid DNA achieves co

151 h levels of foreign gene expression from the intramuscular injection of naked plasmid DNA in mice and

152 Intramuscular injection of Nano-11-antigen formulations

153 Intramuscular injection of nonautologous MSCs can be saf

154 Here we report that intramuscular injection of nonreplicating recombinant ad

155 A single intramuscular injection of pCBWN DNA induced protective

156 Intramuscular injection of pDNA encoding GAD65-IgGFc and

157 ravenously with pentoxifylline 90 min before intramuscular injection of penicillin; 4 patients were n

158 infected adults were randomized to receive 1 intramuscular injection of placebo (n=6) or vaccine at d

159 We have previously shown that intramuscular injection of plasmid DNA encoding the nucl

160 Direct intramuscular injection of PNA-ssODNs targeting the mdx(

161 ' duration were treated with either a single intramuscular injection of polyethylene glycol-modified

162 A single 10 mg intramuscular injection of pSP-HV-GHRH DNA followed by e

163 table transgene expression in mice following intramuscular injection of purified recombinant AAV (rAA

164 ly diagnosed NOD mice were provided a single intramuscular injection of recombinant adeno-associated

165 on-sarcoglycan, was fully restored following intramuscular injection of recombinant delta-sarcoglycan

166 er amounts of dystrophin were detected after intramuscular injection of RTC13.

167 Intramuscular injection of ssGnih-3 provoked a significa

168 Intramuscular injection of succinate also significantly

169 Intramuscular injection of superantigen plasmid DNA in v

170 e, an effect that could not be reproduced by intramuscular injection of superantigen protein.

171 same order of magnitude as those produced by intramuscular injection of the commercially available re

172 Subcutaneous or intramuscular injection of the conjugates elicited a 28-

173 Intramuscular injection of the higher-dose of AVI-4658 r

174 ially induce a stronger immune response than intramuscular injection of the same plasmid DNA.

175 nt of the usual dose), and 119 to receive an intramuscular injection of the standard dose of 15 mug o

176 s by a factor of 14.9, 7.1, and 15.3 for the intramuscular injection of the standard dose.

177 Intramuscular injection of the vaccine protected the lun

178 icles induced comparable immune responses as intramuscular injection of them, but transcutaneous immu

179 Electroporation-mediated intramuscular injection of TIMP-4 expression plasmid res

180 pleural injection of talc (400 mg/kg) and an intramuscular injection of triamcinolone (0.8 mg/kg) 1 d

181 n = 20) in a randomized fashion, followed by intramuscular injection of trivalent influenza vaccine 1

182 Local inflammation induced by the intramuscular injection of turpentine (50 microl/100 gm

183 male Swiss-Webster mice received a 20-microL intramuscular injection of turpentine into the right thi

184 sterile soft-tissue inflammation induced by intramuscular injection of turpentine.

185 in vivo regulation of gene expression after intramuscular injection of two separate adenovirus or ad

186 luated T-cell responses to AAV capsids after intramuscular injection of vectors into mice and nonhuma

187 per limit of the reference value received an intramuscular injection of vitamin K.

188 and, 4 wk postinoculation (WPI) treated with intramuscular injections of 10 mg kg(-1) wk(-1) ActRIIB.

189 [HRT]; men: testosterone enanthate, biweekly intramuscular injections of 100 mg) (n = 35); GH + place

190 Patients also received twice weekly intramuscular injections of 20 mug/kg poly-ICLC.

191 with twin gestations were assigned to weekly intramuscular injections of 250 mg of 17P or matching pl

192 oids and randomly assigned to receive weekly intramuscular injections of 30 microg interferon beta-1a

193 nts were randomly assigned to receive weekly intramuscular injections of 30 microg of interferon beta

194 Each volunteer received 3 spaced intramuscular injections of 50 microg (n = 8), 100 micro

195 0.4 microg of DNA and boosted intradermal or intramuscular injections of 50 microg of DNA failed to p

196 duction of any neuronal protein and supports intramuscular injections of a small interfering RNA-enco

197 Intramuscular injections of Ad-PlGF-1 significantly incr

198 Intramuscular injections of Alhydrogel (plus CpG) adjuva

199 ocked for at least several hours after daily intramuscular injections of alpha-bungarotoxin.

200 n were made before and for 39 weeks after 11 intramuscular injections of ALT-711 at 1.0 mg/kg body we

201 udy, we evaluated the safety and efficacy of intramuscular injections of autologous CD34+ cells in su

202 Intramuscular injections of botulinum toxin A reduce spa

203 ation of stroke, and it is uncertain whether intramuscular injections of botulinum toxin type A reduc

204 Intramuscular injections of compound 41 (the decanoate e

205 The animals were treated with daily intramuscular injections of CsA using doses selected to

206 t chinchillas received three subcutaneous or intramuscular injections of dLOS-conjugated tetanus toxo

207 Intramuscular injections of DNA encoding the CR1 genes p

208 Mice receiving two intramuscular injections of expression plasmid (50 micro

209 ere identified using retrograde labeling via intramuscular injections of Fast Blue or Fluoro Gold, re

210 Intramuscular injections of haloperidol decanoate 25 to

211 Vaccine recipients received 3 intramuscular injections of HIV DNA (4 mg) coding for cl

212 Intramuscular injections of interferon-beta-1a increased

213 ose of either 5 mg or 10 mg) or once-monthly intramuscular injections of leuprolide acetate (at a dos

214 t period and, after safety assessment, three intramuscular injections of long-acting cabotegravir 800

215 uman recombinant IL-2 (PEG-IL-2) or multiple intramuscular injections of murine recombinant IL-12; un

216 Intramuscular injections of NT3 to Egr3-/- mice during t

217 Two patients who had been treated with intramuscular injections of pegylated bovine ADA (PEG-AD

218 We evaluated whether intramuscular injections of plasmids with cDNA encoding

219 s were randomly assigned (2:1) to receive 13 intramuscular injections of recMAGE-A3 with AS15 immunos

220 We then performed in vivo intramuscular injections of recombinant adeno-associated

221 Intramuscular injections of saline (n = 3) or insulin (n

222 Intramuscular injections of Tetanus Toxin C-fragment (TT

223 Overall, the intramuscular injections of the drug exerted salutary ef

224 therapy, each subject received at least four intramuscular injections of the vaccines on days 0, 30,

225 Patients received eight intramuscular injections of their assigned treatment in

226 two visits 21 days apart, subjects received intramuscular injections of vaccine that contained 0.48

227 igned (1:1:1) to receive fulvestrant (500 mg intramuscular injection on day 1, followed by 250 mg dos

228 over 28-day cycles) plus 500 mg fulvestrant (intramuscular injection on days 1 and 15 of cycle 1; the

229 ine or the qHPV vaccine in a series of three intramuscular injections on day 1 and at months 2 and 6.

230 ndomly assigned (1:1) to fulvestrant (500 mg intramuscular injection; on days 0, 14, 28, then every 2

231 ate, 100 mg (n = 14), or placebo (n = 15) by intramuscular injection once a week for 6 months.

232 d to receive either fulvestrant (250 mg, via intramuscular injection, once monthly; n = 313) or tamox

233 of rAd5-based vectors after either a single intramuscular injection or a DNA prime/rAd boost.

234 DNA vaccines are usually given by intramuscular injection or by gene gun delivery of DNA-c

235 zed either systemically with H7 flagellin by intramuscular injection or mucosally via the rectum with

236 ring the immunogenicity of IPV2 delivered by intramuscular injection or Nanopatch immunisation.

237 e strain) (1) by microneedle patch or (2) by intramuscular injection, or received (3) placebo by micr

238 are worker administered microneedle patch or intramuscular injection, or self-administered microneedl

239 l injection, posterior periocular injection, intramuscular injection, or topical eye drops.

240 and block sizes of 2 and 2 to receive three intramuscular injections over 6 months of 9vHPV or qHPV

241 Intramuscular injection provides more rapid and higher p

242 or house-to-house vaccination campaigns (the intramuscular injections require health professionals),

243 igher level of hFIX compared to tail vein or intramuscular injections, respectively.

244 Factor IX gene to skeletal muscle by direct intramuscular injection resulted in therapeutic levels o

245 Intramuscular injections resulted in low expression of a

246 nt with IFNbeta-1a, 30 microg once weekly by intramuscular injection, resulted in a significant decre

247 By intramuscular injection, species D vaccines were markedl

248 tical properties and must be administered by intramuscular injections that limit the total amount of

249 humoral and cellular immune responses, after intramuscular injection the DNA vector encoding the Sc-G

250 rypsin (rAAV-hAAT) vectors were delivered by intramuscular injection to either C57BL/6 (DNA-PKcs(+))

251 al particles) or placebo, administered by 20 intramuscular injections to each leg.

252 U) AdVEGF121, or placebo, administered as 20 intramuscular injections to the index leg in a single se

253 ver, nonreplicating vaccines administered by intramuscular injection using a syringe and needle elici

254 current inactivated vaccines administered by intramuscular injection using a syringe and needle elici

255 XR-NTX was monthly intramuscular injections (Vivitrol; Alkermes) and BUP-NX

256 tivated influenza vaccine (TIV) licensed for intramuscular injection was compared with that of trival

257 s formulations over a period of 28days after intramuscular injection was evaluated by the observed in

258 causal prophylactic antimalarial activity by intramuscular injection, was previously prepared by trea

259 net removal, OTR4120 was administered via an intramuscular injection weekly for up to 4 weeks.

260 inverted question mark, was administered by intramuscular injection weekly.

261 Intramuscular injections were distributed into 8 sites w

262 sal secretions and sera than in animals with intramuscular injection, which showed stronger systemic

263 to protective antigen 14 days after a single intramuscular injection, which were further increased up

264 Pigs in group 3 were vaccinated by intramuscular injection with 10(3.5) 50% tissue culture

265 Pigs in group 1 were vaccinated by intramuscular injection with 200 microg of the chimeric

266 Antimicrobial treatments included daily intramuscular injection with 66,000 IU of procaine penic

267 Five horses were immunized by direct intramuscular injection with a mixture of retroviral vec

268 either by intramuscular needle injection, by intramuscular injection with a needleless injection devi

269 Although other muscles atrophy after intramuscular injection with Botox, extraocular muscles

270 Priming was performed via intramuscular injection with gag and env DNA adsorbed to

271 t velocities of jaw opening before and after intramuscular injection with hypertonic saline (HS, 5%,

272 ged than that we had observed after a single intramuscular injection with inactivated influenza vacci

273 Intramuscular injections with 10(8) CFU of the LHBc-NEO(

274 Mice were immunized by intramuscular injections with a eukaryotic expression ve