ライフサイエンスコーパス: intraplantar

1 In behavioral studies, intraplantar 0.1 microM APDC, a group II agonist, signif

2 Intrathecal (1-100 microg/5 microl), but not intraplantar (10 or 100 microg/50 microl), injection of

3 Inflammatory sensitization was produced by intraplantar administration of capsaicin, formalin or co

4 ement deficiencies, we demonstrated that the intraplantar administration of KLK14 results in C3-assoc

5 Pain hypersensitivity elicited by intraplantar administration of prostaglandin E2, bradyki

6 Intraplantar administration of zymosan produces inflamma

7 ses of primary afferents to thermal stimuli, intraplantar administration of zymosan resulted in signi

8 inal dorsal horn neurons to thermal stimuli, intraplantar administration of zymosan resulted in signi

9 no change or were increased significantly by intraplantar administration of zymosan.

10 ther thermal or mechanical stimuli following intraplantar administration of zymosan.

11 Intraplantar and intrathecal injection of bile acids cau

12 luence the formation of edema, caused by the intraplantar application of polysaccharide lambda-carrag

13 0.1 mg prostaglandin E(2) (PGE(2)) into the intraplantar area of the rat paw produced thermal hypers

14 his effect is dose-dependently attenuated by intraplantar but not by intravenous alpha-helical CRF.

15 Intraplantar but not systemic injection of the ET-A rece

16 s-induced antinociception (NSIA) produced by intraplantar capsaicin injection.

17 The response to intraplantar capsaicin is substantially reduced, as expe

18 Intraplantar capsaicin produced dose- and time-related p

19 eftward shift in the dose-response curve for intraplantar capsaicin-induced inhibition of synovial pl

20 were examined over a 6-h period following an intraplantar carrageenan (0.0-1.0%) injection.

21 inhibitor) or NS398 (COX-2 inhibitor) after intraplantar carrageenan administration.

22 the most notable increases that occur after intraplantar carrageenan are metabolites of 12-lipoxygen

23 nal cord 2h, 1 day, 3 days, and 7 days after intraplantar CFA injection and in the ipsilateral L4/5 d

24 Intraplantar co-application of flagellin and QX-314 (fla

25 Intraplantar coadministration of the TRPA1 receptor anta

26 mg/kg, i.p.), and thermal hyperalgesia after intraplantar complete Freund's adjuvant injection (ED(50

27 ebroventricular (ED(50)>100 nmol, i.c.v.) or intraplantar (ED(50)>500 nmol) routes suggesting that sp

28 rotonergic neurons was used to examine if an intraplantar formalin injection (an acute noxious input)

29 However, injury-induced pain produced by intraplantar formalin is reduced by 70%.

30 Animals exposed to intraplantar formalin or bradykinin injection exhibited

31 Intraplantar Formalin, known to elevate extracellular GL

32 ice showed a 70% reduction in phase 2 of the intraplantar formalin-evoked pain response but only a mo

33 en evaluated behavioral responses to noxious intraplantar formalin.

34 cant reduction of mechanical allodynia after intraplantar Freund's adjuvant (CFA).

35 Pretreatment with intraplantar galanin and bradykinin, compounds known to

36 In support of this, intraplantar GLU + LY produced heat hyperalgesia, and ex

37 inally, the pain hypersensitivity induced by intraplantar IL-1beta was reduced in CKO mice.

38 eversing spontaneous pain induced in mice by intraplantar injection in OD1, a scorpion toxin that pot

39 Intraplantar injection in rats of the ONOO(-) precursor

40 Intraplantar injection of 0.1 or 1 mM S-DHPG results in

41 Intraplantar injection of 100 microg anandamide produced

42 Intraplantar injection of 40 microM AIDA+2% formalin sig

43 Intraplantar injection of a higher dose of URB597 (100 m

44 gnaling was underscored by the findings that intraplantar injection of a monoclonal PGE(2) antibody (

45 Intraplantar injection of a PAR2 agonist caused persiste

46 Intraplantar injection of AEA (10 mug/10 mul) or URB597

47 Intraplantar injection of AEA reduced the hyperalgesia,

48 Furthermore, we determined if intraplantar injection of anandamide altered withdrawal

49 Neither intraplantar injection of anandamide nor vehicle produce

50 Blocking peripheral mGluR activity by intraplantar injection of antagonists LY341495 [(2S)-2-a

51 Similar to PGE(2), an intraplantar injection of capsaicin (0.1 mg) produced a

52 Intraplantar injection of capsaicin in an intact animal

53 Intraplantar injection of capsaicin produced an increase

54 olestanol inhibited nociceptive responses to intraplantar injection of capsaicin, formalin, or comple

55 nished the responses of remaining neurons to intraplantar injection of capsaicin.

56 odel of inflammation-related hyperalgesia by intraplantar injection of carrageenan in rats, inhibitio

57 Intraplantar injection of Cat-S caused inflammation and

58 hat, in addition to mechanical hyperalgesia, intraplantar injection of ceramide (10 mug) led to the d

59 Hindpaw intraplantar injection of complete Freund's adjuvant (CF

60 n by persistent inflammatory pain induced by intraplantar injection of complete Freund's adjuvant (CF

61 preclinical models of inflammatory pain: (i) intraplantar injection of complete Freund's adjuvant (CF

62 recorded in slices from rats inflamed by an intraplantar injection of complete Freund's adjuvant (CF

63 levated during skin inflammation produced by intraplantar injection of complete Freund's adjuvant (CF

64 nflammation and hyperalgesia were induced by intraplantar injection of complete Freund's adjuvant.

65 Intraplantar injection of dilute formalin evokes brief (

66 Intraplantar injection of either capsazepine (10 microg)

67 Furthermore, intraplantar injection of either H(2)O(2) or 15d-PGJ2 ev

68 Intraplantar injection of elastase to mice caused edema

69 Intraplantar injection of ET-1 in naive and, to a greate

70 duces inflammatory pain behaviors induced by intraplantar injection of formalin, carrageenan or compl

71 icking, and lifting responses resulting from intraplantar injection of formalin.

72 duced pain-related behaviours in response to intraplantar injection of formalin.

73 aint and MAP, HR and behavioral responses to intraplantar injection of formalin.

74 In mice, intraplantar injection of HQ at clinically relevant conc

75 Intraplantar injection of icilin did not evoke firing of

76 Intraplantar injection of IL-6 followed immediately by i

77 after the induction of inflammation with an intraplantar injection of lambda-carrageenan.

78 Intraplantar injection of let-7b elicits rapid spontaneo

79 ral thermal sensitization in mice induced by intraplantar injection of mGlu1/5 agonists was also bloc

80 Intraplantar injection of mice with CCL3 decreased their

81 The combined intraplantar injection of non-algesic doses of PAR2 agon

82 Intraplantar injection of PAR(2) agonist also caused pho

83 Intraplantar injection of PAR2 agonist caused mechanical

84 Intraplantar injection of PD-L1 evoked analgesia in naiv

85 tion of IL-6-induced allodynia, a subsequent intraplantar injection of prostaglandin E(2) (PGE(2)) or

86 t hind paw with a profile similar to that of intraplantar injection of prostaglandin E2 (PGE2), which

87 Intravenous or intraplantar injection of RP67580 (6.8 nmol) did not aff

88 y NF-kappaB and p38 kinase activation, since intraplantar injection of SC-514 (0.1-1 mug) or SB 20358

89 was further supported by demonstrating that intraplantar injection of soluble ONOO(-) itself (1 micr

90 Furthermore, intraplantar injection of SRIF antiserum also results in

91 In a dose-dependent manner, intraplantar injection of the SRIF receptor antagonist c

92 n Frey system was used, following unilateral intraplantar injection of TNFalpha or intraarticular inj

93 jection of AEA reduced the hyperalgesia, and intraplantar injection of URB597, an inhibitor of FAAH,

94 yperalgesia, but not inflammation, following intraplantar injection.

95 To test this hypothesis, we used intraplantar injections of interleukin-6 (IL-6) in mice

96 Here, we have demonstrated that intraplantar injections of low dose STZ evoked acute pol

97 cutaneous), spinal (intrathecal) or hindpaw (intraplantar) injections of test compounds, we determine

98 nflammatory injury, in this case produced by intraplantar (ipl) injection of complete Freund's adjuva

99 Intraplantar microinjection of TIP39 caused a paw-withdr

100 sensitivity observed in wild-type mice after intraplantar or intrathecal (spinal) administration of p

101 Furthermore, intraplantar or intrathecal administration of A-784168 b

102 Here we report that peripheral (intraplantar) or spinal (intrathecal) administration of

103 Intraplantar pretreatment with either 5 mM dextrorphan (

104 In behavioral tests, intraplantar S-DHPG (0.1, 1.0, 10 mM) does not change ta

105 Intraplantar URB597 (25 microg in 50 microl) did not, ho

106 Intraplantar URB597 (25 microg in 50 microl) significant