ライフサイエンスコーパス: intratracheal

1 ient mice received 2.5 g/kg of LPS or saline intratracheal.

2 Furthermore, intratracheal administration of Ad-Stat3-EVA caused sign

3 odynamically, and animals were randomized to intratracheal administration of aerosolized AAV1 carryin

4 e to mainstream CS increases AHR after acute intratracheal administration of Aspergillus fumigatus ex

5 highly susceptible to lung injury caused by intratracheal administration of AV1-GFP, an early (E) re

6 A single intratracheal administration of CCL21 gene-modified dend

7 ved in antibacterial defenses, and exogenous intratracheal administration of CG combined with NE does

8 In anesthetized guinea pigs intratracheal administration of DEPs activated airway C-

9 Intratracheal administration of GM-CSF induced final rAM

10 Intratracheal administration of IL-17 provoked a neutrop

11 In initial studies, we found that the intratracheal administration of Klebsiella pneumoniae in

12 Lung injury was induced by intratracheal administration of lipopolysaccharide (5 mg

13 Lung inflammation was induced with intratracheal administration of lipopolysaccharide (LPS)

14 Depletion of macrophages by the intratracheal administration of liposomal clodronate att

15 In this study, we report that intratracheal administration of LMW HA (200 kDa) causes

16 Intratracheal administration of low molecular mass (LMM)

17 Intratracheal administration of LPS (1 mg/kg) in WT mice

18 lation of neuraminidase (NA) 30 min prior to intratracheal administration of LPS increased polymorpho

19 Intratracheal administration of ManLAM in mice resulted

20 ction could be achieved in the lung from the intratracheal administration of mRNA.

21 bited augmented clearance 3 and 7 days after intratracheal administration of P. murina, which correla

22 Intratracheal administration of recombinant mouse comple

23 er examined the effect of IGFBP-5 in vivo by intratracheal administration of replication-deficient ad

24 nhibition of Fas gene expression in lungs by intratracheal administration of small interfering RNA co

25 Intratracheal administration of SP-A to SP-A(-/-) mice e

26 Intratracheal administration of Sph3h was well tolerated

27 rachea of wild-type and Cxcr2(-/-) mice, but intratracheal administration of TNFalpha did not induce

28 Intratracheal administration of Wnt3a or an antibody cap

29 Their intratracheal administration resulted in increased airwa

30 Following intratracheal administration, OVA-specific CD4(+)CD25(+)

31 mor tissues persisted at least 14 days after intratracheal administration.

32 mor-targeted gene delivery in the setting of intratracheal administration.

33 ion, specifically in the upper airways after intratracheal administration.

34 vivo models in two species via intranasal or intratracheal administration.

35 profile with no signs of toxicity following intratracheal administration.

36 drive neutrophilic airways inflammation upon intratracheal adoptive cell transfer into congenic mice.

37 ase was produced in all animals following an intratracheal aerosol of 10(4) CFU delivered, with varia

38 Rats received intratracheal aerosolized LPS (5 mg/kg) or sterile water

39 term lambs were randomly assigned to receive intratracheal aerosolized surfactant or bolus surfactant

40 SPDEF was induced following intratracheal allergen exposure and after Th2 cytokine s

41 longer than B-cell-deficient mice after both intratracheal and intravenous infections.

42 Intratracheal anti-MHC class I Abs or hydrochloric acid

43 ockout (Rag2(-/-)) mice by means of repeated intratracheal applications of SplD.

44 ramin+RB2) or TXA2 receptor (SQ29548), or by intratracheal apyrase.

45 ignificantly higher mortality in response to intratracheal bacterial challenge.

46 Using an intratracheal bacterial endotoxin LPS challenge model, w

47 erium tuberculosis strain was established by intratracheal bacterial instillation followed by proper

48 Mice were given intratracheal bleomycin (0.04 units) and assessed for AE

49 ility to exacerbate lung scarring induced by intratracheal bleomycin administration.

50 in two models of pulmonary fibrosis in mice (intratracheal bleomycin and inducible TGF-beta1).

51 Of note, lung fibrosis induced after intratracheal bleomycin challenge in mice could be preve

52 (+)CD25(hi)Foxp3(+) cells in the lung during intratracheal bleomycin challenge; however, this unexpec

53 Intratracheal bleomycin exposure results in substantial

54 ly) daily for 7 days beginning 10 days after intratracheal bleomycin had improved survival over contr

55 two different models of pulmonary fibrosis, intratracheal bleomycin instillation and thoracic irradi

56 decreases lung hydroxyproline content after intratracheal bleomycin to levels comparable with that o

57 To test this hypothesis, mice treated with intratracheal bleomycin were exposed to low-concentratio

58 eater lung neutrophil influx at 1 week after intratracheal bleomycin, greater weight loss during the

59 After intratracheal bleomycin, L188Q SFTPC-expressing mice dev

60 protected from pulmonary fibrosis induced by intratracheal bleomycin, with minimal alterations in the

61 F-beta activation in the lungs 14 days after intratracheal bleomycin.

62 Cs) in draining lymph nodes was inhibited by intratracheal but not intraperitoneal delivery of AAL-R.

63 Intratracheal, but not i.v., administration of naive lun

64 and 10 mg/kg, respectively), intubated using intratracheal cannula, and ventilated (9 mL/kg, 150 min)

65 Intratracheal cardiolipin administration in mice recapit

66 Intratracheal challenge of transgenic mice with Gram-pos

67 Mice that undergo i.p. sensitization and intratracheal challenge with 10(6) S. chartarum spores d

68 ctin-1 (Dectin-1(-/-)) are more sensitive to intratracheal challenge with A. fumigatus than control m

69 28 levels peaked in the lungs 24 hours after intratracheal challenge with CRA, whereas eotaxin expres

70 r challenge with lipopolysaccharide (LPS) or intratracheal challenge with Escherichia coli.

71 Intratracheal challenge with Haemophilus influenza enhan

72 impaired pulmonary bacterial clearance after intratracheal challenge with Klebsiella pneumoniae.

73 ed the responses of BALB/c mice following an intratracheal challenge with S. pneumoniae after 5 weeks

74 onent 4 knockout (C4 KO) mice against lethal intratracheal challenge with serotype 8 pneumococcus, bu

75 anced pulmonary bacterial clearance after an intratracheal challenge with Streptococcus pneumoniae.

76 d in sterilizing immunity upon an aggressive intratracheal challenge with the 2009 H1N1 pandemic viru

77 lmonary immune response of Ag-primed mice to intratracheal challenge with the particulate T cell-depe

78 Using a validated mouse model of intratracheal challenge, we investigated the role of TLR

79 Intratracheal coadministration of IL-17A and TNF-alpha i

80 eal and to a lesser extent intramuscular and intratracheal deliveries led to trafficking of mRNA-LNPs

81 particle structure-function relationships on intratracheal delivery and related biodistribution and p

82 Transduction efficacy after intratracheal delivery of AAV1 was confirmed by beta-gal

83 d NF-kappaB activity in airway epithelium by intratracheal delivery of adenoviral vectors expressing

84 stablished PAH, gene transfer of SERCA2a via intratracheal delivery of aerosolized adeno-associated v

85 Intratracheal delivery of aerosolized monoclonal antibod

86 nflammation, injury, and mortality following intratracheal delivery of Escherichia coli LPS.

87 Intratracheal delivery of stem cells into injured or dis

88 In this report, we show that intratracheal delivery of the chiral sphingosine analog

89 Intratracheal delivery of water-soluble S1P(1) receptor

90 vaccine was delivered by both intranasal and intratracheal delivery than when it was delivered intran

91 The lung inflammatory response caused by intratracheal deposition of IgG immune complexes (IC) in

92 lergic airway inflammation received a single intratracheal dose of ovalbumin (OVA), 2 days after the

93 el in A/J mice, on day 60 following a single intratracheal dose with or without single intravenous pa

94 onal microparticles on day 21 after a single intratracheal dosing of dry powders in A/J mice.

95 pressor transgene overexpression or sham and intratracheal E. coli inoculation, rats underwent 4 hour

96 (100 mg/m(3) total particulate matter) or by intratracheal elastase injection.

97 A second group was treated with intratracheal elastase to induce emphysema.

98 In a mouse model of intratracheal endotoxin-induced alveolitis, coexposure t

99 isplayed augmented inflammatory responses to intratracheal endotoxin.

100 LPS; 5 mg/kg of body weight) was followed by intratracheal Escherichia coli (10(6) CFU) in wild-type

101 In animals (n = 142) administered intratracheal Escherichia coli challenge, compared to pl

102 onomicrobial pulmonary infection by using an intratracheal Escherichia coli infection model of pneumo

103 We observed that repeated intratracheal exposure to SplD led to IL-33 and eotaxin

104 HO-1 induction inhibited PMC migration after intratracheal fibrogenic injury.

105 tory epithelial permeability, as revealed by intratracheal FITC-dextran tracking, serum Club Cell pro

106 n apoptosis was noted in the lungs following intratracheal flu infection of iNOS knockout mice.

107 In initial studies, we found that the intratracheal (i.t.) administration of L. pneumophila to

108 model of pulmonary LPS tolerance induced by intratracheal (i.t.) administration of LPS.

109 s (s.c.) administration of c-di-GMP prior to intratracheal (i.t.) challenge with Klebsiella pneumonia

110 CBA/J mice were highly susceptible to intratracheal (i.t.) Cryptococcus neoformans infection r

111 As a model of ALI, we administered intratracheal (i.t.) LPS to mice and observed peak lung

112 Compared with mice given intratracheal IL-13 alone, those exposed to IL-13 and IL

113 Intratracheal IL-33 challenge resulted in decreased C5aR

114 osinophilic lung inflammation in response to intratracheal IL-4 and exogenous histamine restores resp

115 Intratracheal immunization with a higher dose of a heter

116 Using a murine intratracheal infection model, our results demonstrated

117 odel, pili were critically important with an intratracheal infection model.

118 Intratracheal infection of cynomolgus macaques with thes

119 Intratracheal infection of Syrian hamsters with Ad14p1 c

120 ges and less inflammation in the lungs after intratracheal infection than control mice.

121 in in the pulmonary vasculature following an intratracheal infection with a systemic viral pathogen.

122 n of K-Ras(G12V) expression in lung cells by intratracheal infection with adenoviral-Cre particles ge

123 survival compared with wild-type mice after intratracheal infection with K. pneumoniae.

124 double-knockout mice were studied following intratracheal infection with VV, VVDeltaK3L, or VVDeltaE

125 o the airways of naive wild-type mice before intratracheal inhalation of GC frass resulted in signifi

126 ve BALB/c mice were challenged with a single intratracheal inhalation of GC frass.

127 t, BALB/c mice were challenged with a single intratracheal inhalation of Hsp72 and killed 4 h later.

128 This potentiating effect was rescued by intratracheal injection of apyrase.

129 increased on day 7, 14, and 21 after single intratracheal injection of bleomycin (BLM).

130 Using intratracheal injection of bleomycin or hydrochloric aci

131 Intratracheal injection of crocidolite asbestos in mice

132 Both groups of mice then underwent intratracheal injection of either Pseudomonas aeruginosa

133 in the model of acute lung injury caused by intratracheal injection of LPS.

134 Intratracheal injection of PLY caused lethal acute lung

135 of palpable tumors, all animals received an intratracheal injection of Pseudomonas aeruginosa.

136 Intratracheal injection of S. mucilaginosus in C57BL/6 m

137 ophil response in G-CSFR(-/-) mice following intratracheal injection with Pseudomonas aeruginosa-lade

138 muL of sterile saline was delivered through intratracheal injection.

139 pulmonary pathogen Pseudomonas aeruginosa by intratracheal injection.

140 cellular infection, they were defective upon intratracheal inoculation into the lungs of A/J mice, an

141 Conventional intratracheal inoculation of a liquid suspension of H5N1

142 allergic bronchopulmonary mycosis following intratracheal inoculation of Cryptococcus neoformans 240

143 model of pulmonary cryptococcosis induced by intratracheal inoculation of Cryptococcus neoformans.

144 A single intranasal/intratracheal inoculation of juvenile baboons with BPZE1

145 Likewise, after intratracheal inoculation of Naip5+ mice, the yield of L

146 olized bacteria, the rat model has relied on intratracheal inoculation of organisms because of safety

147 We hypothesized that intratracheal inoculation of rats with a USA300 CA-MRSA

148 erated in C57BL/6 mice by low- and high-dose intratracheal inoculation with Pseudomonas aeruginosa.

149 bility to infect the lungs of A/J mice after intratracheal inoculation, indicating that legiobactin i

150 recovered only from nasal epithelium; after intratracheal inoculation, it was recovered also from tr

151 enovirus primed a response to the subsequent intratracheal inoculation, suggesting a route to optimiz

152 Following intratracheal inoculation, Y. pestis was rapidly interna

153 in the African green monkey (AGM) following intratracheal inoculation.

154 d for attenuation of virulence in mice after intratracheal inoculation.

155 er virus titers in the nasal turbinates than intratracheal inoculation.

156 hesus macaques as a model for MERS-CoV using intratracheal inoculation.

157 cruitment of neutrophils to the lung on D-DT intratracheal installation of C57BL/6J mice with an EC50

158 ted eosinophilic inflammation in response to intratracheal installation of IL-13.

159 Intratracheal instillation (IT) of the aqueous extracts

160 ley (SD) or Fisher 344 (F344) rats following intratracheal instillation (IT).

161 neutrophils with purified vitronectin before intratracheal instillation decreased efferocytosis in vi

162 ther group of C57BL/6J mice received IL-4 by intratracheal instillation for 7 days.

163 en proposed as a useful alternative to rapid intratracheal instillation for the delivery of exogenous

164 se of paclitaxel by up to 100-fold following intratracheal instillation in healthy mice.

165 , in vivo augmentation of lung ceramides via intratracheal instillation in rats significantly decreas

166 Following intratracheal instillation into naive mice, PS50G were p

167 Importantly, intratracheal instillation of 8-pCPT-cGMP in BALB/c mice

168 Intratracheal instillation of a lethal dose of ricin (20

169 y enhanced its anti-tumor efficacy following intratracheal instillation of a single dose in a Lewis l

170 g in human neutrophils and demonstrated that intratracheal instillation of a TAT-conjugated PKCdelta

171 ach, the secondary challenge was replaced by intratracheal instillation of allergen-pulsed bone marro

172 Intratracheal instillation of anti-MHC class I Abs, but

173 -type or EC-SOD-null mice were exposed to an intratracheal instillation of asbestos or bleomycin.

174 ne model of pulmonary fibrosis induced by an intratracheal instillation of bleomycin (control mice we

175 To investigate this issue, we used intratracheal instillation of bleomycin as a model of ac

176 s induced in female C57BL/6 mice by a single intratracheal instillation of bleomycin.

177 development of pulmonary fibrosis after the intratracheal instillation of bleomycin.

178 After 11 challenges, intratracheal instillation of bone marrow-derived dendri

179 Rats were colonized by intratracheal instillation of Candida albicans.

180 on or i.p. administration of live E. coli or intratracheal instillation of carrageenan plus myelopero

181 The single intratracheal instillation of caspase-3 siRNA not only a

182 ory distress syndrome was induced in rats by intratracheal instillation of E. coli (1.5-2 x 10 CFU/kg

183 Intratracheal instillation of either lipid caused substa

184 Intratracheal instillation of endotoxin-free HA (25 mug)

185 Intratracheal instillation of endotoxin-free low molecul

186 In addition, intratracheal instillation of IL-36alpha enhanced mRNA e

187 e day postburn, some of the animals received intratracheal instillation of Klebsiella pneumoniae and

188 Intratracheal instillation of L-selectin-deficient (L-Se

189 Intratracheal instillation of leptin at a dose that was

190 Wild-type or tlr4 mice were challenged by intratracheal instillation of lipopolysaccharide (0.3 mg

191 Moreover, intratracheal instillation of lipopolysaccharide induced

192 long-term macrophage depletion by repetitive intratracheal instillation of liposomal clodronate.

193 One h after intratracheal instillation of liposomal fasudil, mean pu

194 Intratracheal instillation of low concentrations of aden

195 g ECs freshly isolated from mice showed that intratracheal instillation of LPS induced ROCK activatio

196 However, intratracheal instillation of LPS resulted in accelerate

197 After intratracheal instillation of LPS, ROS generation was im

198 als overexpressing Activin-A or treated with intratracheal instillation of LPS.

199 her by ectopic expression of Activin-A or by intratracheal instillation of LPS.

200 Intratracheal instillation of neuraminidase (NA) 30 min

201 ung neutrophils were isolated 24 hours after intratracheal instillation of PBS or S. pneumoniae, and

202 Similarly, intratracheal instillation of PGD(2) enhanced removal of

203 Intratracheal instillation of PLY into C57BL6 mice cause

204 Twenty-four hours after the intratracheal instillation of PM(2.5), wild-type mice sh

205 study, we observed that pneumonia induced by intratracheal instillation of Pseudomonas aeruginosa (PA

206 Intratracheal instillation of recombinant mouse IL-36alp

207 Intratracheal instillation of siRNA did not induce lung

208 either intraperitoneal delivery of AAL-R nor intratracheal instillation of the non-phosphorylatable s

209 Intratracheal instillation of the PAR1-specific peptide

210 In the present study, intratracheal instillation of this PKCdelta inhibitor re

211 anaesthetized, spontaneously breathing rats, intratracheal instillation of trypsin (0.8 mg ml(-1), 0.

212 Treatment of mice with intratracheal instillation of TSG6 prevented LPS-induced

213 utrophil-mediated pulmonary injury evoked by intratracheal instillation or i.p. administration of liv

214 We found that upon intratracheal instillation, particulates such as aluminu

215 recombinant replicated in the monkeys after intratracheal instillation, the first demonstration of r

216 ore efficiently than control PA01 2 hours of intratracheal instillation.

217 impaired compared with BLT1(+/+) BMDCs after intratracheal instillation.

218 delivered therapeutically to rats after LPS intratracheal instillation.

219 omeric IP-10 were retained in the lung after intratracheal instillation.

220 D was readily detected in the lung 5 h after intratracheal instillation.

221 CD8+ T cells into the airways of mice after intratracheal instillation.

222 optosis were assessed 72 h after a single PM intratracheal instillation.

223 ays after transplantation, the mice received intratracheal instillations of the Fas-activating mAb Jo

224 inoculation of monkeys via the subcutaneous, intratracheal, intravenous, or oral-nasal-conjunctival r

225 ion of the virus by intranasal inhalation or intratracheal intubation.

226 ination, and reduced survival in response to intratracheal K. pneumoniae administration.

227 activation of NF-kappaB and MAPKs following intratracheal K. pneumoniae infection.

228 ophils to the lung triggered by inhaled LPS, intratracheal KC chemokine, and intratracheal Klebsiella

229 response to neutrophil migration induced by intratracheal keratinocyte chemokine.

230 inhaled LPS, intratracheal KC chemokine, and intratracheal Klebsiella pneumoniae and impairs pulmonar

231 (5 ng/g b.wt.) in the presence or absence of intratracheal lipopolysaccharide (51 microg).

232 After intratracheal lipopolysaccharide instillation, preterm n

233 In the intratracheal lipopolysaccharide model, 1,500 IU of intr

234 We administered intratracheal lipopolysaccharide to wild-type mice and o

235 ne models of cecal ligation and puncture and intratracheal lipopolysaccharide were undertaken in norm

236 In control lambs, intratracheal lipopolysaccharides caused septic shock an

237 eutrophil recruitment in the lungs following intratracheal LPS administration in dfy(-/-) and dfy(+/+

238 lammation and hyperresponsiveness induced by intratracheal LPS administration.

239 esolution, we exposed wild type (WT) mice to intratracheal LPS and assessed the response at intervals

240 As a model, we administered intratracheal LPS and observed peak lung injury at 3 d,

241 In mice challenged with intratracheal LPS and then exposed to febrile range hype

242 Male C57BL/6J mice received 300 microg/kg intratracheal LPS and were exposed to acrolein (5 parts

243 transferred into lungs of naive mice before intratracheal LPS challenge diminished proinflammatory c

244 Intratracheal LPS elicited an exaggerated systemic infla

245 llular apoptosis in C57BL/6J mice exposed to intratracheal LPS for 24 h.

246 nase-M, Toll-interacting protein, and A20 by intratracheal LPS in vivo and in macrophages in vitro wa

247 In vivo, aerosolized intratracheal LPS induced lung injury with profound incr

248 Intratracheal LPS induced release of pro-interleukin-1al

249 to four different groups: control, MV only, intratracheal LPS only, and MV + LPS.

250 In mice treated with intratracheal LPS or keratinocyte chemokine, neutrophil

251 he combination of mechanical ventilation and intratracheal LPS produces significantly more injury to

252 s had pulmonary inflammatory responses after intratracheal LPS that were similar to those of wt mice.

253 ra2b to ALI, utilizing a two-hit model where intratracheal LPS treatment is followed by injurious mec

254 When iNOS-/- mice were exposed to intratracheal LPS, early lung injury was attenuated; how

255 In response to intratracheal LPS, neutrophils migrate into the lung, an

256 ADD45a(-/-) mice are modestly susceptible to intratracheal LPS-induced lung injury and profoundly sus

257 n and animals allocated at random to receive intratracheal maternal administration of nitrogen (n=8)

258 Results from a group of mice receiving intratracheal normal saline without surgical interventio

259 Upon a combination of intratracheal, ocular, oral, and intranasal inoculation

260 We found that C57BL/6 mice given intratracheal or s.c. immunization of conidia prior to c

261 flagellin induced strong protection against intratracheal P. aeruginosa-induced lethality, which was

262 -induced PAH rats than oral, intravenous, or intratracheal plain sildenafil did, when administered at

263 ild-type mice to develop edema with low-dose intratracheal PLY, correlating with reduced pulmonary EN

264 g protein L-plastin (LPL) succumb rapidly to intratracheal pneumococcal infection.

265 Intratracheal post-treatment with LPA (5 microm) reduced

266 Intratracheal pretreatment with a leptin receptor inhibi

267 and increased mortality when challenged with intratracheal Pseudomonas as compared with nonseptic con

268 We compared intratracheal Pseudomonas infection in wild type and cav

269 ed sepsis followed by secondary challenge by intratracheal Pseudomonasaeruginosa.

270 Intratracheal recombinant human SP-D prevented shock cau

271 to the systemic circulation was prevented by intratracheal recombinant human SP-D.

272 Administration of intratracheal recombinant MCP-1 (rMCP-1) to MCP-1(-/-) m

273 Finally, the intratracheal reconstitution of IL-23 in TLR9(-/-) mice

274 from the Ad recombinants (intramuscular and intratracheal, respectively), too few DNA priming immuni

275 Intriguingly, administration of intratracheal rG-CSF to MCP-1(-/-) mice after K. pneumon

276 Intratracheal rhSOD and/or iNO rapidly increase oxygenat

277 Intratracheal rhSOD decreased the enhanced lung 3-nitrot

278 Early intratracheal rhSOD treatment improves oxygenation in pr

279 (ALI), we delivered LPS or bleomycin by the intratracheal route to MMP-8(-/-) mice versus wild-type

280 to bleomycin, we delivered bleomycin by the intratracheal route to wild-type (WT) versus Mmp-8(-/-)

281 ependent part of the trachea, leading to an "intratracheal route" of colonization of the lungs.

282 s of African green monkeys by the intranasal/intratracheal route.

283 with influenza virus A/Anhui/1/2013 via the intratracheal route.

284 us A/Netherlands/602/09 by the intranasal or intratracheal route.

285 n of rhesus macaques via both intranasal and intratracheal routes with MuV-IA led to the typical clin

286 mental infection in pigs, via intranasal and intratracheal routes, was performed using one representa

287 e and female mice were treated with 0.2 g/kg intratracheal silica, and lung injury was assessed 1, 3,

288 ted from mice, 48 hours after treatment with intratracheal small interfering RNA targeting Fas, contr

289 Administration of intratracheal SP-A to Sp-a(-/-) mice induced the translo

290 ferred about 50% protection against a lethal intratracheal spore challenge by the virulent B. anthrac

291 ene delivery system that offers an effective intratracheal strategy for administering lung cancer gen

292 erfused hearts harvested after sepsis alone (intratracheal Streptococcus pneumoniae, 0.4 mL of 1 x 10

293 Despite relatively mild lung injury, intratracheal TNF-alpha-treated TRAF1-/- mice exhibited

294 ted with anti-MHC I antibody in vitro before intratracheal transfer failed to modulate AHR or inflamm

295 Furthermore, naive mice receiving intratracheal transfer of airway CD8 TRM cells lacking t

296 ith anti-Thy1.2 mAb and replaced by means of intratracheal transfer of ex vivo expanded Thy1.1 ILC2s.

297 mined by determining the response of mice to intratracheal transfer of OVA-pulsed or OVA-alpha-galact

298 Intratracheal transfers of enriched CD68(+) cells isolat

299 in familial interstitial pneumonia and (ii) intratracheal treatment with the protein misfolding agen

300 With a complementary model, intratracheal tunicamycin treatment failed to induce lun