ライフサイエンスコーパス: intravenous dose

1 currently recommended for adults (twice the intravenous dose).

2 metric mean ratio of the subcutaneous to the intravenous dose.

3 vided doses starting at five times the daily intravenous dose.

4 ion in the tumor was less than 1% of 20mg/kg intravenous dose.

5 micromol/L and 13 400 micromol/L for a 50-g intravenous dose.

6 rmacokinetics were determined after a single intravenous dose.

7 oral voriconazole (VRC) doses are lower than intravenous doses.

8 1 oral dose of HAV was equivalent to 10(4.5) intravenous doses.

9 ieving an MED of 1.5 mg/kg, following weekly intravenous dosing.

10 duced TNF release and shock as compared with intravenous dosing.

11 d the safety and pharmacodynamics of single, intravenous doses (0.025, 0.05, and 0.1 mg/kg) of Hemati

12 After the single intravenous dose (1.52 +/- 0.47 mg/kg), gastric pH incre

13 r patients with IgG4-RSD were treated with 2 intravenous doses (1 gram each) of rituximab.

14 Except for the maximum intravenous dose (10 microg/kg), neither delivery method

15 vasopressin receptor antagonist, at a single intravenous dose (10, 20, or 40 mg) or placebo.

16 been given a single oral (10 g) and a single intravenous dose (30 g) of exogenous L-arginine.

17 esiologist infusing a single, subanesthetic, intravenous dose, and required hospitalization for at le

18 time in tumor tissue, is well-tolerated upon intravenous dosing, and is highly efficacious in the COL

19 lethal Staphylococcus aureus infection after intravenous dosing, and one compound showed protective e

20 loride vehicle in a divided subcutaneous and intravenous dose at PN commencement.

21 re measured after administration of oral and intravenous doses at a dose range of 0.015 to 1.25 g, an

22 Intravenous-dose clearance, volume of distribution at st

23 ock the LH surge in all animals, whereas all intravenous doses consistently blocked the LH surge.

24 After administration of a single intravenous dose, each drug was rapidly cleared from pla

25 Pharmacokinetics support intravenous dosing every 28 days.

26 or 7 days (with or without an initial 400-mg intravenous dose) followed by placebo for 7 days (n = 12

27 The suggested intravenous dose for a phase II study will be 1.5 mg/m2/

28 brain and cerebrospinal fluid after repeated intravenous dosing for up to 4 months in Tg2576 transgen

29 to-plasma ratio of approximately 3 following intravenous dosing in mice.

30 ugs in use against HAT are toxic and require intravenous dosing, new drugs are needed.

31 one experiment, 2 monkeys received a single intravenous dose of (225)Ac-HuM195 at 28 kBq/kg.

32 ts (6 PC, 2 BC, and 2 UBC) received a single intravenous dose of (68)Ga-NOTA-AE105 (154 +/- 59 MBq; r

33 ts (6 PC, 2 BC, and 2 UBC) received a single intravenous dose of (68)Ga-NOTA-AE105 (154 +/- 59 MBq; r

34 Each patient received tacrolimus (4-hr intravenous dose of 0.04 mg/kg between postoperative day

35 at an oral dose of 0.8 mg/kg in rats and an intravenous dose of 0.06 mg/kg in baboons.

36 After randomization, an intravenous dose of 0.125 mg/kg lenercept or placebo was

37 ion in the allergic guinea pig by 50%, at an intravenous dose of 10 mg/kg.

38 A single preoperative intravenous dose of 1000 mg of cefazolin (cefazolin grou

39 Patients were treated with O(6)-BG at an intravenous dose of 120 mg/m(2) followed 1 hour later by

40 tructure infections received either a single intravenous dose of 1200 mg of oritavancin or a regimen

41 The drug is administered as a single intravenous dose of 1200 mg over 3 hours in adult patien

42 We have found that a single intravenous dose of 150 microCi (200 microg) 90Y-CHX-A"-

43 as not detected in plasma 5 min following an intravenous dose of 2 mg/kg.

44 plasminogen activator (tPA) using a standard intravenous dose of 3.3mg/kg (20% bolus, 80% infused), w

45 lant protein c2 was administered as a single intravenous dose of 30 mug/kg body weight at onset of he

46 a 31% T/C at its solubility-limited maximum intravenous dose of 33 micromol/kg in MDA-MB-435 breast

47 atic malignancies were administered a single intravenous dose of 5 mCi 111In-diethylenetriaminepentaa

48 al resection were each administered a single intravenous dose of 5 mg of isothiocyanatobenzyl diethyl

49 Cetuximab was given as an intravenous dose of 500 mg/m(2) every 2 weeks with regim

50 We infused a single intravenous dose of a codon-optimized adeno-associated v

51 Single intravenous dose of AB103 (0.5 or 0.25 mg/kg) within 6 h

52 nteractive web response system to receive an intravenous dose of ALD403 1000 mg or placebo.

53 No safety concerns were noted with an intravenous dose of ALD403 1000 mg.

54 ntidepressant effects resulted from a single intravenous dose of an N-methyl-D-aspartate antagonist.

55 ntidepressant effects resulted from a single intravenous dose of an N-methyl-D-aspartate antagonist;

56 Nurses then administered an intravenous dose of an opioid from a sliding scale presc

57 The evidence favors an intravenous dose of around 1 mg of elemental iron per da

58 A or Ad5PA and then challenged with a lethal intravenous dose of Bacillus anthracis lethal toxin.

59 ed by measuring changes in blood T2 after an intravenous dose of BMS 180550 were used to determine cl

60 Patients received four intravenous dose of bortezomib (1.3 mg/m(2)) over 2 week

61 gram, to receive either a single, continuous intravenous dose of brexanolone or placebo for 60 h.

62 atients were recruited and received a single intravenous dose of cefazolin (15 mg/kg) and tobramycin

63 f oral doxycycline, with or without a single intravenous dose of ceftriaxone, or 20 days of oral doxy

64 In the present study a single intravenous dose of clomipramine (200 mg) was compared w

65 Two days later, a single intravenous dose of diclofenac (2 mg/kg) (treated animal

66 Ten pigs (35-45 kg) received an intravenous dose of disrupted mitochondrial products and

67 e sequentially allocated to receive a single intravenous dose of either 0.1, 1, 5, or 10 mg/kg of MRA

68 atment in a randomized fashion with a single intravenous dose of either CDP571 (5 mg/kg) or an equiva

69 > 20, ability to swallow, and </= one single intravenous dose of empiric antibiotic therapy before st

70 5 concomitant with or 4 hours after a single intravenous dose of hemoglobin abolished hemoglobin-indu

71 , 8, 20, and 40 mg/kg) and received a single intravenous dose of HGS004 or placebo.

72 naive Wistar rats immediately after a single intravenous dose of indinavir.

73 in rats administered a nontoxic 0.5 mumol/kg intravenous dose of inorganic mercury with or without 2.

74 Rapid anti-OCD effects from a single intravenous dose of ketamine can persist for at least 1

75 trecogin alfa (activated) infusion before an intravenous dose of lipopolysaccharide.

76 A low intravenous dose of M8-B did not affect T(b) at either a

77 was reduced for at least 7 days by a single intravenous dose of mAb 2021.

78 treated rejection (P=0.035) and lower median intravenous dose of methyl-prednisolone (P=0.017) than N

79 s, which regressed completely after a single intravenous dose of MV-NIS, and in MM1 myeloma xenograft

80 Patients were randomized to receive a single intravenous dose of placebo or an infusion of ibutilide

81 Patients received a single intravenous dose of placebo, 10 000 U/kg of pegorgotein,

82 In contrast, a high intravenous dose of probenecid (250 mg/kg) only slightly

83 ith magnetic resonance imaging (MRI) that an intravenous dose of protamine labeled with gadolinium ac

84 he kidney and that a single 50- to 200-ng/kg intravenous dose of purified Stx-1 results in thrombocyt

85 After a single intravenous dose of rifampin (1 mg/kg), a 1.7-fold incre

86 ry immune thrombocytopenia received a single intravenous dose of rozrolimupab ranging from 75 to 300

87 Most of an intravenous dose of species C adenovirus serotype 5 (Ad5

88 -blind, placebo-controlled trial of a single intravenous dose of synthetic human secretin in 60 child

89 00 mg) was administered followed by the same intravenous dose of tacrolimus, and subsequent samples w

90 mouse model of IP, we administered a single intravenous dose of the adeno-associated virus (AAV) vec

91 We assessed the effects of a single 20 mg intravenous dose of the arginine vasopressin receptor 1A

92 Within 90 minutes after receiving a single intravenous dose of the drug, all six volunteers had a s

93 ients with treatment-resistant MDD, a single intravenous dose of the low-trapping NMDA channel blocke

94 A single intravenous dose of thrombopoietin (0.3 to 2.4 microgram

95 lysis on transporter-deficient mice after an intravenous dose of topotecan (4 mg/kg).

96 ndomly assigned patients to receive a single intravenous dose of ustekinumab (either 130 mg or approx

97 After intravenous doses of 1 or 10 mg/kg body weight were admi

98 (10-25 mg weekly) were randomized to receive intravenous doses of 10 mg/kg MDX-1100 (n = 35) or place

99 Intravenous doses of 200, 600, and 1500 mg/kg were admin

100 After intravenous doses of 250 units/g body weight were admini

101 After intravenous doses of 250 units/g of native GALNS, and 25

102 ic monoclonal antibody against TNF-alpha, in intravenous doses of 3 or 10 mg per kilogram of body wei

103 adult patients with HPP received 3 ascending intravenous doses of 5, 10, and 20 mg/kg BPS804, a fully

104 abeled mAb B72.3 in combination with various intravenous doses of AP.

105 Specifically, rats were given intravenous doses of CsA 2.5 mg/kg and SRL 1 mg/kg, alon

106 The effects of four increasing intravenous doses of diazepam on saccadic eye movement v

107 The hemodynamic effects of cumulative intravenous doses of FE 204038, terlipressin, or vehicle

108 tent of tissue deposition following multiple intravenous doses of gadolinium-based contrast agent (GB

109 y comparing GCV levels after single oral and intravenous doses of GCV.

110 the effects of acute administration of small intravenous doses of heroin on rates of glucose utilizat

111 9 bpm) and decreased heart rate responses to intravenous doses of isoproterenol.

112 uential placebo injections and one after two intravenous doses of methylphenidate.

113 okers received saline followed by escalating intravenous doses of nicotine (0.5 and 1.0 mg/70 kg) giv

114 We administered intravenous doses of nivolumab and ipilimumab in patient

115 ynamic contrast enhanced MRI that sequential intravenous doses of protamine in 12 tumor-bearing rats

116 dose (MTD) and safety of single and multiple intravenous doses of PV701 as a single agent in patients

117 kinetics, and antitumor activity of multiple intravenous doses of rhApo2L/TRAIL in patients with adva

118 of trial entry, were recruited to receive 2 intravenous doses of rituximab (1,000 mg), administered

119 hetic baroreflex sensitivity was assessed by intravenous doses of sodium nitroprusside and phenylephr

120 reshold device, abdominal binding, and large intravenous doses of sodium nitroprusside.

121 Single intravenous doses of this oligonucleotide were given to

122 Participants received initial intravenous doses of trastuzumab deruxtecan from 0.8 to

123 to be nonemetic in a canine emesis model at intravenous doses of up to 3 mg/kg.

124 s, with a plasma elimination half-life after intravenous dosing of 4.5 h, oral bioavailability of 77%

125 In subsequent experiments, standard systemic intravenous dosing of stabilized siRNA 72 hours after in

126 Carboplatin was administered as a single intravenous dose once every 21 days at a target area und

127 Patients received one 1000 microg intravenous dose or 1000 microg daily for 7 days inhaled

128 -5, which was administered as either a 75-mg intravenous dose or a 100-mg subcutaneous dose, or place

129 lprednisolone (1 mg/kg) plus four additional intravenous doses over 24 h, and Group B received intrav

130 ate that PEG-rmMGDF administered as a single intravenous dose potently stimulates platelet production

131 Four PV701 intravenous dosing regimens were evaluated: (1) single d

132 The pharmacokinetic study of DMA at oral and intravenous doses showed its C(max) = 1 hour, bioavailab

133 olae-immunotargeted fluorophores even at low intravenous doses showed rapid and robust pumping across

134 0%) after the 2 largest oral doses and the 1 intravenous dose, suggesting 100% bioavailability of the

135 trations were higher after administration of intravenous doses than after administration of oral dose

136 o be treated 18 hours before craniotomy with intravenous doses that ranged between 40 and 100 mg/m2 g

137 -daily oral doses and 200-300 mg twice-daily intravenous doses, the predicted probabilities of achiev

138 metabolites after administration of a bolus intravenous dose to rats.

139 r levels of NTP predictive of efficacy after intravenous dosing to rats.

140 Temsirolimus was administered in a 250-mg intravenous dose weekly.

141 us rituximab and 40 (45%) patients given the intravenous dose, with differences between administratio