ライフサイエンスコーパス: intravesicular

1 (ii) Electron microscopy reveals intravesicular 20-nm particles, similar to those formed

2 rnal medium stimulated proton efflux and the intravesicular accumulation of radiolabeled gentamicin,

3 cal for pHi regulation as it is activated by intravesicular acid pH.

4 mal tubule was measured from the kinetics of intravesicular acidification in response to rapid mixing

5 I]IUdR in patients with liver metastases and intravesicular administration in patients with bladder c

6 more "protected" routes: intra-arterial and intravesicular administration.

7 Importantly, the intravesicular alpha-syn is more prone to aggregation th

8 Here we present a metallic pyramid array for intravesicular analysis by combining site-selective diel

9 Intravesicular Asc may also play a role in relieving cat

10 ated with a rapid transmembrane oxidation of intravesicular ascorbate by extravesicular ferricyanide.

11 on of ADP and ATP (rather than exchange with intravesicular ATP) is demonstrated by high pressure liq

12 Hederagenin induced intravesicular budding but no pore formation.

13 wo types of large vesicles with high and low intravesicular [Ca2+].

14 to resist bladder colonization in vivo after intravesicular challenge with type 1-fimbriated E. coli.

15 changes in transmitter content such that the intravesicular concentration of transmitter is maintaine

16 -ApoE and betaA suggested presence of stable intravesicular conjugates.

17 vesicles and a target membrane that releases intravesicular content through a transient, nanometer-si

18 o the cytoplasm alters the physical state of intravesicular contents in preparation for release.

19 secretory vesicles dock and fuse to release intravesicular contents to the outside during cell secre

20 Direct application of such forces to the intravesicular end of the TM domain resulted in tilting

21 ld be accessible to proteolysis in a soluble intravesicular environment.

22 e FM1-43 and an antibody directed against an intravesicular epitope of synaptotagmin I.

23 cilia with disrupted axonemes and perturbed intravesicular fluid flow in Kupffer's vesicle.

24 ntaneously, we can dissociate the effects of intravesicular free radical generation on spontaneous ne

25 this study, we acutely probe the effects of intravesicular free radical generation on synaptic vesic

26 presynaptic vesicle release regulation--the intravesicular glutamate fill state of the vesicle.

27 ues within the transmembrane regions and the intravesicular glycosylation of SV2 are required for its

28 Thus, intravesicular localization and secretion are part of no

29 acid substitutions occurred in a 56-residue intravesicular loop (IV1 domain) of the vesicle protein

30 but YqkI-dependent Na(+) uptake depended on intravesicular malate and extravesicular lactate.

31 YqkI-dependent lactate uptake depended on intravesicular malate and extravesicular Na(+).

32 icroscopy has shown that, during exocytosis, intravesicular markers escape without collapse of the ve

33 rent vesicles, without causing the mixing of intravesicular material.

34 consistent with chemical dissociation of the intravesicular matrix or gel.

35 ns from the cytosolic ascorbate (Asc) to the intravesicular matrix to provide reducing equivalents fo

36 begins with molecular rearrangements at the intravesicular membrane leaflet and not between the appo

37 Our data suggest that the intravesicular N-glycosylation site of synaptotagmin 1 c

38 The Ca(2+) uptake requires intravesicular Na(+) and is stimulated by an inside posi

39 IAP is most commonly measured using the intravesicular or "bladder" technique.

40 s indicate that exposure to high pH, whether intravesicular or extracellular, accelerates release of

41 mide, both of which are expected to increase intravesicular pH by inhibiting V-type H+-ATPase, had no

42 her these effects are attributable to raised intravesicular pH due to proton transport through VMATs.

43 ined the effect of ethanol administration on intravesicular pH in intact hepatocytes by applying a fl

44 Although intravesicular pH levels in D. discoideum show small aci

45 shown to bind to the vesicle membrane at the intravesicular pH of 5.5 and to be released from it at a

46 ns aggregated in the presence of Ca2+ at the intravesicular pH of 5.5.

47 The effects of extracellular Zn2+ and pH and intravesicular pH on insulin and 5-hydroxytryptamine (5-

48 ng active loading strategies to generate low intravesicular pH to prolong drug retention and increase

49 d these three approaches with measurement of intravesicular pH to show very fast FA binding and trans

50 The intravesicular pH was approximately 6.5, supporting only

51 Using pH-sensitive probes, the intravesicular pH was determined and found to be equival

52 Simulations to estimate the intravesicular pH were conducted to demonstrate that acc

53 r H(+)-ATPase decreased exponentially as the intravesicular pH(in) decreased, suggesting modulation o

54 the conductance of sodium and calcium ions, intravesicular pH, trafficking and excitability.

55 fined conditions allowing extravesicular pH, intravesicular pH, transmembrane pH and membrane potenti

56 tuted M2 using a pH-sensitive dye to monitor intravesicular pH, we conclude that bath pH weakly affec

57 ic weak base ammonium chloride, which raises intravesicular pH.

58 rmeate secretory vesicle membranes and raise intravesicular pH.

59 y loaded liposomal formulations having a low intravesicular pH.

60 hibition of G34 cleavage, perhaps by raising intravesicular pH.

61 lease correlated with alterations in the low intravesicular pH.

62 6 ml h(-)(1)) evoked periodic sharp rises in intravesicular pressure accompanied by rhythmic bursting

63 Triplicate intravesicular pressure measurements were performed at l

64 r transporters, and by a highly glycosylated intravesicular sequence.

65 sion in a solution that is hypertonic to the intravesicular solution decreases, and may abolish, chan

66 icles in a solution that is hypotonic to the intravesicular solution increases channel activity where

67 occurred in right-side-out vesicles when the intravesicular space contained either Na+ or K+ but not

68 nded to changes in the osmotically sensitive intravesicular space, and was saturable, exhibiting a Km

69 hen aminoglycosides were present only in the intravesicular space.

70 for K exchange allowing acidification of the intravesicular space.

71 It was concluded that intravesicular storage conditions and extracellular ions

72 lope that also enclosed the nematode-derived intravesicular structure.

73 f PfCRT, these changes would tend to promote intravesicular trapping of chloroquine (a weak base) and

74 Caspase 3-mediated apoptosis depends on intravesicular trypsinogen activation induced by CTSB, n

75 eteral bladder insertion sites and shortened intravesicular tunnel lengths that correlated with VUR.

76 ontrols; (2) after bladder inflammation with intravesicular turpentine; and (3) after bilateral hypog

77 the percentage of sealed vesicles and their intravesicular volume and sidedness using biochemical ap

78 Intravesicular volume estimated by incorporation of radi