1 We demonstrated two different models of
an intrinsic PEEP lung model.
2 volume air flow, internal lung pressure,
and intrinsic PEEP were measured.
3 The interactions
between intrinsic PEEP and externally applied PEEP were differen
4 However,
if intrinsic PEEP was induced without dynamic airway closur
5 It is unlikely that the difference
in intrinsic PEEP between the study groups was clinically i
6 ernal PEEP, both above and below the
initial intrinsic PEEP, were applied.
7 In the model with flow
limitation,
intrinsic PEEP was created by replacing a portion of the
8 In the model without flow
limitation,
intrinsic PEEP was generated with a fixed linear resisto
9 range, 0-3.1 cm H2O), compared with a
median intrinsic PEEP of 0.5 cm H2O (interquartile range, 0-1.5
10 mized to the 6 mL/kg protocol, with a
median intrinsic PEEP of 1.3 cm H2O (interquartile range, 0-3.1
11 both study groups, and difference of
median intrinsic PEEP between the groups was <1 cm H2O.
12 The amount
of intrinsic PEEP was very low in both study groups, and di
13 ratory circuit to produce a similar level
of intrinsic PEEP.
14 rnal PEEP has little effect on the levels
of intrinsic PEEP.
15 model may be useful for the future study
of intrinsic PEEP and pulmonary mechanics.
16 In a subgroup of ARDS Network
subjects,
intrinsic PEEP was statistically significantly higher in
17 We found
that intrinsic PEEP was higher among subjects randomized to t
18 ected if the external PEEP was less than
the intrinsic PEEP in the lung model with flow limitation.