ライフサイエンスコーパス: introduction of

1 The introduction of (18)F-labeled prostate-specific membrane

2 In addition, introduction of 3xMyc-FXR1 via adeno-associated virus in

3 n of pre-evaporated water aerosol allows the introduction of 8mg of solid sample without extinguishin

4 8.7M] reduction was projected with the 2020 introduction of a 50%-efficacy vaccine gradually scaled

5 The introduction of a carboxamide group between the thiazole

6 INTERPRETATION: Introduction of a comprehensive smoke-free policy appear

7 Moreover, introduction of a disulfide bond in the bridging sheet r

8 Through the introduction of a disulfide bond, we succeeded in arrest

9 tients from 6 months before to 2 years after introduction of a financial incentive program that provi

10 The most common strategy is the introduction of a frameshift into the open reading frame

11 Additional introduction of a FVIIa-M306D mutation to uncouple the s

12 numbers, were the exception, as indicated by introduction of a genetically and antigenically diverse

13 The introduction of a hierarchical architecture is an effect

14 it industry largely recovered because of the introduction of a less-susceptible yellow-fleshed cultiv

15 serpentine path) and was facilitated by the introduction of a lossless ion switch that allowed ions

16 Introduction of a m-fluorine in the benzyl moiety eventu

17 roof-of-concept for the TFT, by showing that introduction of a male fertility-impairing mtDNA haploty

18 Conversely, the introduction of a methyl group at the methylene hinge co

19 chloroplast protein PGRL1 was rescued by the introduction of a mitochondrial mutation affecting respi

20 Remarkably, the introduction of a non-native disulfide bond was critical

21 ble ectodomain of TF (sTF) was engineered by introduction of a nonperturbing cystine bridge (FVIIa Q6

22 The introduction of a novel ionic environment, which is comp

23 An artificial, disruptive challenge; i.e., introduction of a novel object, is used to cause reprodu

24 nt process restoring movement accuracy after introduction of a perturbation, is affected at the pre-c

25 The introduction of a plastic-crystal electrolyte interphase

26 ERPRETATION: This analysis suggests that the introduction of a PrEP programme for MSM in the UK is co

27 variate sensitivity analyses to evaluate the introduction of a PrEP programme with sexual event-based

28 ed for ethyl methacrylate, which enables the introduction of a quaternary carbon center.

29 To understand why introduction of a single CH3 group in five-position of t

30 Here, we show that the introduction of a single lipid-facing arginine residue n

31 The introduction of a standard approach to trimethoprim-sulf

32 n which VFs can be labeled in live cells via introduction of a TC tag into the muNS open reading fram

33 her engineered in multilayer graphene by the introduction of a twist angle between different layers t

34 accomplished using azidoiodinane for direct introduction of a useful azide group onto a broad scope

35 The introduction of a vaccine targeting 13 serotypes (PCV13)

36 roindene with C11(R)-configuration, (ii) the introduction of a vinyl group as a masked OH at C6, (iii

37 In addition, we have shown that the introduction of a W55T mutation impairs receptor binding

38 bination (CSR) occurs through the deliberate introduction of activation-induced cytidine deaminase (A

39 The introduction of active transition metal sites (TMSs) in

40 tion as thin films, surface development, and introduction of additional properties are very much dema

41 By introduction of Al2O3 nanoparticles, the MZ depth of Ni

42 Twenty years after the introduction of alcohol septal ablation (ASA) for the tr

43 demonstrate that the locations of origin and introduction of alien birds, and their identities, were

44 ditors, ABEs enable the direct, programmable introduction of all four transition mutations without do

45 specific type of complementary foods, early introduction of all plant-based foods was associated wit

46 The introduction of allergen molecules has had a major effec

47 ge-related within-sequence features, and the introduction of an action-related feedback cue temporari

48 rted into an As(III)-responsive repressor by introduction of an additional cysteine that allows for t

49 We also found that introduction of an additional fully occupied N-linked gl

50 Phyllosticta citricarpa, is the most recent introduction of an exotic citrus pathogen into Florida a

51 Following the introduction of an externally hyperpolarized compound, r

52 The aim was to investigate whether the introduction of an hsTnT assay is associated with reduce

53 m of alpha-MnO2 material, in addition to the introduction of an improved in situ TEM biasing techniqu

54 ecessary imaging contrast often requires the introduction of an optical label which can potentially c

55 interplay of multiple metal centers enables introduction of an orthogonal alkyne handle into monoclo

56 The introduction of anti-vascular endothelial growth factor

57 de life expectancy at age 15 years since the introduction of ART, and the shortfall of the population

58 We speculate that this might relate to the introduction of artemisinin-based combination therapies.

59 lt in an overinterpretation of drift and the introduction of artifact states.

60 in human physiology and pathology; thus, the introduction of artificial receptors for the real-time q

61 Reconstruction was repeated after the introduction of artificial signal voids in the AC map to

62 This objective called for the introduction of at least 1 dose of inactivated polio vac

63 trategic Plan 2013-2018 called for the rapid introduction of at least one dose of IPV into routine im

64 The introduction of azoles further revolutionized the treatm

65 review the evidence to determine whether the introduction of baked hen's egg or cow's milk into the d

66 The introduction of bare-metal stents (BMS) has represented

67 The introduction of beta-cell autoantigens via the gut throu

68 The introduction of better cardiac imaging techniques could

69 ults provide important insights into how the introduction of biologically relevant, but poorly unders

70 2016, a precautionary action to prevent the introduction of Bsal to the U.S. through the importation

71 y persist for finite time, necessitating the introduction of buffer zones, within which an appropriat

72 Introduction of bulky methionine for glycine at two poin

73 mendous success in the last decade after the introduction of cadaveric biologic scaffolds.

74 and 44 children followed a pathway after the introduction of CAEP and were tested with unaided and ai

75 at a significantly earlier age following the introduction of CAEP.

76 Since the introduction of calcium imaging to monitor neuronal acti

77 However, the introduction of carbinol units required the development

78 hanged the functionality of biochar with the introduction of carboxylic and phenolic groups, a reduct

79 The introduction of Cas9-directed genome editing has expande

80 Depletion or introduction of catalytically inactive mutation of ClpP

81 We reasoned that de novo introduction of CD22 ligands in RBCs should abolish B ce

82 comparable clinical situation occurred after introduction of cetuximab, a chimeric mouse-human antibo

83 In electronic and optical settings the introduction of chiral transport, in which carrier propa

84 second modification to the 1.54T-CUA was the introduction of chitosan and gold nanoparticles (CS/GNPs

85 The introduction of chlorine atoms on the indole ring of mal

86 etween the study recruitment in 1985 and the introduction of cognitive tests to the study in 1997.

87 The introduction of combined antiretroviral therapy has chan

88 Early introduction of complementary foods at 3-6 months of age

89 to extend exclusive breastfeeding and delay introduction of complementary foods until 6 months of ag

90 ates (TSs) for the uncatalyzed reaction, the introduction of conformational descriptors, and the use

91 The tangled1 mutant was fully rescued by introduction of cortical division site localized TANGLED

92 The introduction of cytosine nucleobase 2 into position 24 o

93 ompared with people ineligible for DACA, the introduction of DACA was associated with no significant

94 Validation of the model by introduction of data of secreted adiponectin yielded a v

95 is often used for peptide enrichment or the introduction of desirable tags.

96 Despite introduction of diagnostic criteria and some advances in

97 ial stewardship are likely to arise from the introduction of diagnostic M. genitalium nucleic acid am

98 Early introduction of dietary peanut in high-risk infants with

99 merolae nuclear transformation method by the introduction of diphtheria toxin genes into the transfor

100 Despite the introduction of direct oral anticoagulants (DOACs), the

101 , and despite the improvements linked to the introduction of direct oral anticoagulants, more than on

102 re we show how the electrokinetically driven introduction of DNA molecules into a nanochannel is faci

103 Introduction of DOACs in routine practice was associated

104 ncreased TDP1-promoter activity, whereas the introduction of dominant-negative NRF-1 repressed such a

105 ylori infection has been associated with the introduction of double-strand breaks in epithelial cells

106 The introduction of DSBs is initiated by activation-induced

107 ychoses in rural or urban settings since the introduction of early intervention psychosis services.

108 Epidemiologic evidence suggests delayed introduction of egg might not protect against egg allerg

109 We demonstrate that introduction of equivalent stop codons in the full-lengt

110 The introduction of ester and carboxylate functionalities at

111 and visualizing RNAs typically relies on the introduction of exogenous tags.

112 edicted to emerge due to climate change, the introduction of exotic species and land-use change.

113 Introduction of expression vectors for miR-424 reduced b

114 nt self-doping accomplishes this without the introduction of external dopants, and therefore the tetr

115 ompetitor systems have no such solution; the introduction of extreme strategies can easily affect the

116 The calculations indicate that introduction of Fe dopants changes the character of the

117 erric nontronites was observed following the introduction of Fe(II) into predominantly-Fe(III) octahe

118 their physicochemical properties through the introduction of fluorine is of paramount importance in m

119 echanism of the BLUF protein AppABLUF by the introduction of fluorotyrosine (F-Tyr) analogues that mo

120 ive, we demonstrate fructose transport after introduction of four amino acids derived from GLUT5.

121 the angle of incidence usually requires the introduction of gain media into the system.

122 We propose the introduction of genetic testing early in the diagnostic

123 The oral introduction of glutamic acid increased virus acquisitio

124 Introduction of Gly770 into two dacomitinib-resistant EG

125 Followed by the introduction of gold nanoparticles coated magnetic micro

126 probably indicating ongoing invasion and re-introduction of H. halys.

127 as improved during the last decades with the introduction of high-dose methotrexate.

128 After the introduction of high-throughput sequencing, genotyping a

129 HIV-positive people have decreased since the introduction of highly active antiretroviral therapy (HA

130 INTERPRETATION: Our study suggests that the introduction of HPV vaccination in England will initiall

131 The changes in quality measures after the introduction of HVBP were assessed for matched samples o

132 The introduction of immunomodulatory drugs (IMiDs) and prote

133 ith type 2 poliovirus-containing vaccine and introduction of inactivated polio vaccine in routine imm

134 le highlights key lessons learned during the introduction of inactivated poliovirus vaccine in 3 coun

135 vaccine beginning with the type 2 component, introduction of inactivated poliovirus vaccine, strength

136 Conversely, the introduction of inducers of epithelial-mesenchymal trans

137 repeated stochastic fadeouts after multiple introductions of infectious rodents migrating from neigh

138 The introduction of "intention to split policy" resulted in

139 a challenge across all viruses tested here; introduction of international quantitative standards may

140 process and the role played by NITAGs in the introduction of IPV in the routine immunization program

141 countries were using IPV except Egypt, where introduction of IPV was delayed by a global shortage.

142 procurement and regulatory issues before the introductions of IPV and bOPV.

143 Introduction of just a few heterologous genes can endow

144 Introduction of K68R MnSOD rescued mitochondrial redox s

145 al foods claiming health benefits led to the introduction of key improvements in the production of hi

146 The introduction of kidney paired donation (KPD) programs re

147 nt advances in colorectal cancer surgery are introduction of laparoscopy and FFT implementation.

148 amenable to efficient estimation through the introduction of latent variables and the appropriate app

149 The introduction of liquid microjet and flow cell technologi

150 Introductions of low-pathogenic avian influenza (LPAI) v

151 This is accomplished by the introduction of luminance and spatial noise thereby elim

152 of innovative products has given rise to the introduction of macro and microalgae in food industry.

153 recent hospital C difficile infection rates, introduction of mandatory surveillance in individuals ol

154 educed ejection fraction with the sequential introduction of medications including angiotensin-conver

155 In preparation for the introduction of MenAfriVac, a meningococcal group A conj

156 the lesions were no longer visible after the introduction of metallic artifacts.

157 Recent years have heralded the introduction of metasurfaces that advantageously combine

158 pecific biological mechanisms underlying the introduction of methane-derived carbon into the food web

159 during postnatal colonisation, or after the introduction of microbiota into germ-free models.

160 open gastrectomy (OG) for cancer during the introduction of MIG in the Netherlands.

161 referably enter into the zeolite-Y pores and introduction of Mn(2+) would cause aggregation of each o

162 ng molecular WOCs with solids along with the introduction of molecular concepts into heterogeneous WO

163 ne methyltransferase 7 (PRMT7) catalyzes the introduction of monomethylation marks at the arginine re

164 lower hemoglobin concentrations, while early introduction of most animal-based foods was not.

165 rm MRSA surveillance study revealed multiple introductions of MRSA CC398 in a UK Equine Hospital, ide

166 NHAs) and syngeneic mouse glioma models, the introduction of mutant IDH1 or treatment with 2HG reduce

167 d in this system using genetic correction or introduction of mutations via CRISPR/Cas9 and that this

168 With metallic MoB, the introduction of n-type semiconductive g-C3 N4 induces a

169 Central to the method is the introduction of nanopores into the organic semiconductor

170 ly hazardous antipsychotics halved after the introduction of national dementia strategies.

171 In addition, we show that introduction of negative charge at tyrosine 18 shifts Ta

172 The introduction of new and more complex medical devices wil

173 These new probes work well but require the introduction of new labels that may interfere with the p

174 lation was only transiently disturbed by the introduction of new lineages before a new equilibrium wa

175 nsive and laborious to produce; however, the introduction of new rAb fragments and single-domain Abs

176 ed engineering of endogenous pathways or the introduction of new traits.

177 The introduction of next-generation sequencing and array-bas

178 amplified SPR response is observed upon the introduction of nonlinear HCR system.

179 Examples include the introduction of novel immunohistochemical markers that s

180 l melanoma metastases has changed due to the introduction of novel systemic treatments that can resul

181 Although the introduction of novel targeted agents has improved patie

182 The introduction of novel technologies with faster scan spee

183 f FL patients has recently improved with the introduction of novel therapies, there is significant he

184 s.IMPORTANCE IAV pandemics are caused by the introduction of novel viruses that are capable of effici

185 tarting point for clinicians considering the introduction of one of the rules.

186 The introduction of open, high-field, 1.0T (HFO) MR scanners

187 ts receiving only breast milk and those with introduction of other foods before 6 months were categor

188 nsion of the outbreak in Brazil and multiple introductions of outbreak strains into Puerto Rico, Hond

189 onditions persisted for several months after introduction of oxidizing conditions, presumably due to

190 ass spectrometer was undertaken to allow the introduction of ozone into the high-pressure trapping io

191 es, RP=BR, and demonstrate their use for the introduction of P=B units into organic systems.

192 4 and XBP1 and upregulation of BCL6, whereas introduction of p52 or p100 into GC cells resulted in di

193 nds for specified aetiologies in relation to introduction of PCR testing and measles-mumps-rubella (M

194 cal disease in each of the 4 years after the introduction of PCV13 alone or PCV10 and PCV13 with the

195 4 years after the introduction of PCV13 alone or PCV10 and PCV13, the pool

196 sed prevalence of MDR serotype 35B after the introduction of PCV13 was directly associated with the e

197 Medical guidelines on the introduction of peanut as well as other allergenic foods

198 trategies are under investigation, but early introduction of peanut has been advised as a public heal

199 We sought to assess the effect of early introduction of peanut on the development of allergic di

200 allenges), and the timing and approaches for introduction of peanut-containing foods in the health ca

201 iatrics in 2000, which recommended a delayed introduction of peanut.

202 tion while breast-feeding paired with direct introduction of peanuts in the first year of life was as

203 mportant improvement in recent years was the introduction of peptide receptor radionuclide therapy wi

204 The introduction of periods of fast replication by MTC leads

205 essitate a degree of selection driven by the introduction of PfHRP2-based RDT-guided treatment.

206 gery has advanced to the point that Kelman's introduction of phacoemulsification and use of intraocul

207 Moreover, the introduction of PhCN to the reactions involving secondar

208 sources to evaluate the association between introduction of PMI and child mortality rates in sub-Sah

209 Introduction of PMI was associated with increased covera

210 for all-cause pneumonia associated with the introduction of pneumococcal conjugate vaccines (PCVs) i

211 The introduction of "poison" oligonucleotides that specifica

212 sma robustness resulting from the concurrent introduction of pre-evaporated water aerosol allows the

213 Introduction of primary HPV screening from 2019 could re

214 ns that can be drastically diminished by the introduction of protective H2 gas at ambient pressure.

215 The introduction of Pseudomonas syringae pv. actinidiae (Psa

216 Following the introduction of PSS1 into the soybean cultivar Williams

217 Introduction of PTEN into a PTEN null prostate cancer ce

218 The introduction of realistic seasonality in vector populati

219 A set of PCR cassettes facilitates the introduction of recombinant DNA sequences into the lambd

220 howed that both the doping of sulfur and the introduction of rGO worked as designed, and the TiO2-S/r

221 the metal-ligand framework, affected by the introduction of rigidity and in the presence of external

222 .043) comparing phase 1 and phase 2 (formal introduction of risk stratification).

223 (N = 500, phase 1) performed prior to formal introduction of risk stratification.

224 variants has increased dramatically with the introduction of RNA-sequencing technology, which enables

225 ) in Australia compared with the theoretical introduction of routine-only (12-13 years) vaccination.

226 The development of iNTS vaccines and the introduction of S Typhi conjugate vaccines should be con

227 Introduction of sample-specific barcodes during reverse

228 With the introduction of selective n-type doping and a nonrelief

229 ation of this state can be influenced by the introduction of serine or threonine at sequence position

230 pidemics were the result of intercontinental introductions of seventh pandemic El Tor V. cholerae and

231 very, with an emphasis on case studies where introduction of silicon has created a benefit over its a

232 anced by methylation of the quinoline and by introduction of simple chiral moieties, resulting in a c

233 The recent introduction of simultaneous whole-body PET/MR scanners

234 eins (RNPs) can facilitate the high-fidelity introduction of single-base substitutions via HDR follow

235 Further, the introduction of SOD1(G93A) and TDP43(A315T), established

236 e in a dose-dependent manner, even after the introduction of solid foods.

237 With the introduction of spectral domain optical coherence tomogr

238 The introduction of stents resulted in more stable early res

239 opriate chiral acids as catalysts or through introduction of stoichiometric boronic acid-based additi

240 of long-avoided aryne intermediates for the introduction of structural motifs that have conventional

241 Introduction of such a PrEP programme, with around 4000

242 able capacity for self-organization and that introduction of such macromolecular complexes may advanc

243 Peninsula) seem to indicate that an earlier introduction of such technique in Europe around 0.96-0.7

244 The regiodivergent introduction of sugars at the C3, C5, and C11 positions

245 With the recent introduction of surveillance guidelines for gastric atro

246 Moreover, introduction of Symbiodinium into naive Aiptasia larvae

247 Current methodologies for the exogenous introduction of synthetic biomolecules often result in s

248 Remarkably, introduction of T150D K5 mutants into KtyII-lacking (Kty

249 e two components of the liquid caused by the introduction of the alcohol.

250 While introduction of the amide-motif in the phytosphingosine

251 -concentrating mechanism will necessitate co-introduction of the ancillary molecular components requi

252 h the first spectra acquired 7 minutes after introduction of the antibiotic.

253 Spontaneous gating caused by the introduction of the beta2(L285R) mutation was also reduc

254 Once the Dha is installed, the introduction of the desired functionality is limited onl

255 The introduction of the endosymbiotic bacterium Wolbachia in

256 , meningitis, and death, was unchanged after introduction of the EOS calculator.

257 The introduction of the guidelines had no appreciable effect

258 Introduction of the heptavalent pneumococcal conjugate v

259 s (CCMV) are able to perform catalysis after introduction of the His-tag.

260 We have found that introduction of the MALDI-generated ions into an electro

261 Subsequent introduction of the methyl group and functional group tr

262 In contrast, the introduction of the mutation seen in our family led to a

263 We suggest that introduction of the pdm2009 H1 virus, to which most of t

264 Here we show that the introduction of the protic additive phenol to ethers can

265 er-type extra ccmB 5' termini only after the introduction of the RPF4 allele from Ler.

266 Introduction of the shed ectodomain of NgR1 is sufficien

267 Additionally, introduction of the three missense mutations from the af

268 theoretical evaluation demonstrated that the introduction of the triazole core in the scaffold of non

269 substrate spectrum for aromatic compounds by introduction of the triple mutation A74G/F87V/L188Q and

270 creased by 98% (from 0.60 to 0.01) after the introduction of the two-dose MMR vaccine.

271 the rate of diagnosis of dementia after the introduction of the UK National Dementia Strategy (p<0.0

272 atients has increased substantially with the introduction of the Xpert MTB/RIF test, used for tubercu

273 The introduction of these changes into the parental virus co

274 We aimed to measure the impact of the introduction of these vaccines on pneumonia incidence.

275 -molecule rotation assays indicated that the introduction of this Mycobacterium-specific domain decre

276 ee to which increasing experience during the introduction of this procedure, separated from other out

277 served in 1960, less than one year after the introduction of this second generation beta-lactam antib

278 tic tool based on enumeration, but since the introduction of this tool to the clinic in 2004, further

279 ged to carry out the decision, planning, and introduction of this vaccine and subsequent switch to th

280 everal classes of repeated sequences and the introduction of thousands of designer changes may affect

281 The introduction of transcatheter aortic valve replacement (

282 aches for the speedy, stable and marker-free introduction of transgenes encoding the DiCre recombinas

283 1A locus to enable phiC31 integrase mediated introduction of transgenes has been generated.

284 genitor cells in vitro Consistent with this, introduction of TRBP into the mouse embryonic brain in u

285 The subsequent introduction of Triton X-100 and CoQ10 causes the MLs ly

286 us TCR alpha and beta genes, followed by the introduction of tumor-specific TCR genes, and that prove

287 Introduction of two humanizing mutations in the S6 segme

288 emission was weakened or even canceled upon introduction of two or three strong EWGs, the emission o

289 Introduction of two SIVmac316 CD4-binding site residues

290 demic in sub-Saharan Africa, and despite the introduction of universal hepatitis B vaccination and ef

291 cts into a ketone would enable the selective introduction of unnatural functionality.

292 In comparison, the introduction of uracil nucleobase 3 had a minimal effect

293 observe how these rates have varied with the introduction of vaccines and improved diagnostics.

294 This reaction enables introduction of various aryl groups to construct triaryl

295 is new strategy allows full control over the introduction of various sensitive functional groups at d

296 With the introduction of WebGL and HTML5 technologies in recent y

297 Introduction of whole-egg powder into the diets of high-

298 Introduction of wild type pgp1 into 11168-GS did not res

299 This event followed the suspected introduction of ZIKV in Brazil in 2013.

300 We estimate that the first introduction of ZIKV to Brazil likely occurred between A