ライフサイエンスコーパス: introduction of @2 into

1 dulation of the lipophilicity, and strategic introduction of fluorine into 1.

2 The introduction of alpha5 into 293 cells expressing alpha4+

3 ate the effects on ligand recognition of the introduction of a histidine into a hydrophobic cavity in

4 ocal optical modification of the director or introduction of colloidal inclusions into a moderately c

5 We hoped to learn how the introduction of cooperative cells into a cell population

6 g the selectable marker hph to be excised by introduction of Cre recombinase into a strain containing

7 e displays high substrate tolerance allowing introduction of D-Ala into a range of non-native substra

8 eradication is routinely attempted following introduction of disease into a new region, failure is co

9 re we show how the electrokinetically driven introduction of DNA molecules into a nanochannel is faci

10 Introduction of fdG into a DNA duplex decreases the Tm b

11 The judicious introduction of fluorine into a molecule can productivel

12 fluorinated aryl iodides also allows for the introduction of fluorine into a molecule of interest.

13 Introduction of hurP into a yaeL mutant of V. cholerae a

14 Doping--the intentional introduction of impurities into a material--is fundament

15 ic acid and fucose dependent manner, and the introduction of intact EG into a B cell line facilitated

16 Soft ionization methods for the introduction of labile biomolecules into a mass spectrom

17 work, we demonstrate for the first time the introduction of pi-complexation into a porous aromatic f

18 Introduction of PTEN into a PTEN null prostate cancer ce

19 Introduction of the mutations into a second virus also i

20 Introduction of these changes into a replication-deficie

21 Introduction of this mutant into a viral life cycle mode

22 an M41L/T215Y mutant in the presence of ZDV, introduction of this mutation into a D67N/K70R/K219Q bac

23 Health provides an example of the successful introduction of this vaccine into a developing world cou

24 glois reagent (NaSO2CF3) and TBHP allows the introduction of trifluoromethyl groups into a variety of

25 Here we report that introduction of V. cholerae into a nutrient-poor filter

26 -colonized LTACH residents may interrupt the introduction of KPCs into acute care hospitals.

27 ts in cilium development were rescued by the introduction of p27(Kip1) into Acvr1-deficient MEFs, imp

28 The stable introduction of E1A-12 into Ad5 nontumorigenic cells res

29 We expect this method to allow the introduction of fluorine atoms into advanced, highly fun

30 Introduction of point mutations into alpha-helix 7 at OR

31 Introduction of the mutation into AML1-ETO had minimal i

32 t chemical shifts calculations show that the introduction of boron into an aromatic 6pi-electron syst

33 Upon introduction of heterologous sequences into an organism-

34 er, the question as to how to achieve timely introduction of peanut into an infant's diet in a safe a

35 The introduction of percutaneous tracheostomy into an intens

36 Collectively, these results suggest that the introduction of RDDs into an individual's IL12RB1 mRNA r

37 irus to one naive animal every 7 weeks after introduction of RhCMV-WT into an uninfected cohort.

38 Introduction of the sequence into an infectious molecula

39 Electrophoretic introduction of antibody into and along the molecular si

40 The introduction of antigen into animals causes antigen-spec

41 n southern Australia was responsible for the introduction of lead pollution into Antarctica at the en

42 The introduction of mutant Muc2 into Apc(1638N/+) and Apc(Mi

43 In addition, introduction of AR into AR-negative prostate cancer cell

44 Introduction of BCR-ABL into Arf-null severe combined im

45 Moreover, the introduction of R373 into b12-sensitive NL4.3 and AD8 en

46 sting correlation methods and, if necessary, introduction of novel methods into biology is appropriat

47 Introduction of Pax6 retrovirally into bone marrow macro

48 -mediated cytotoxicity and apoptosis whereas introduction of EphA2 into both wild-type and p53-null M

49 The introduction of this technology into both research and c

50 did not result in tumorigenic conversion but introduction of Bcl-XL into c-Myc-expressing cells gener

51 sing Runx2 repression by adenoviral-mediated introduction of Runx2 into C3H10T1/2 cells can prevent t

52 Introduction of miR-22 into cancer cells reduced the lev

53 of Rap1 activity in CaP metastasis in vivo, introduction of activated Rap1 into CaP cells dramatical

54 The introduction of Candida albicans into cefoperazone-treat

55 s to reduced MHC class I expression, whereas introduction of NLRC5 into cell types with very low expr

56 hese methods have been extended to allow the introduction of caged proteins into cells by permeabiliz

57 Upon introduction of preformed seeds into cells overexpressin

58 cytology-negative results is critical to the introduction of HPV testing into cervical screening.

59 tinin (HA) gene suggests at least 2 separate introductions of resistance into circulating populations

60 covers several synthesis strategies for the introduction of hierarchy into "classical" porous glass

61 Although better drugs are needed, introduction of new agents into clinical trials in paedi

62 otic resistance is spreading faster than the introduction of new compounds into clinical practice, ca

63 important issues need to be addressed before introduction of these therapies into clinical practice.

64 entral nervous system side effects precluded introduction of this drug into clinical practice.

65 the drug discovery process will speed up the introduction of new drugs into clinics.

66 gy was applied to the direct, regioselective introduction of isopropyl groups into complex, biologica

67 Here we aim to provide guidance on the safe introduction of rubella vaccine into countries in the fa

68 find preliminary evidence for the beneficial introduction of exotic alleles into cultivated rice geno

69 clarify the membrane topology of NuoM by the introduction of histidine tags into different positions

70 payers to estimate the budget impact of the introduction of Mydriasert into different clinical setti

71 port an extremely simple and fast method for introduction of barcodes into DNA libraries made from 5

72 After introduction of the construct into E. coli and induction

73 The introduction of Trp into either of the two host turn seq

74 The introduction of NeuroD1 into embryonic retinal explants

75 es of secondary prevention include potential introduction of bias into epidemiologic studies estimati

76 ogenetic analyses reveal a pattern of serial introductions of multiple genotypes into Ethiopia in ass

77 teady population growth usually assumed, the introduction of agriculture into Europe was followed by

78 change factors (GEFs), we show that upon the introduction of hRgr into fibroblast cell lines, it is a

79 This study tests the hypothesis that the introduction of craniofacial sutures into finite element

80 Live cell imaging reveals that introduction of these mutations into full-length PKCalph

81 tivation, and the defects were rescued by re-introduction of Gab2 into Gab2(-/-) cells.

82 Introduction of p38alpha(Y323F) into Gadd45alpha-deficie

83 during postnatal colonisation, or after the introduction of microbiota into germ-free models.

84 Accelerated development and introduction of rotavirus vaccines into global immunisat

85 developed an RNA virus-based vector for the introduction of desired traits into grapevine without he

86 Introduction of acetate into groundwater at the Rifle In

87 ng molecular WOCs with solids along with the introduction of molecular concepts into heterogeneous WO

88 Introduction of miR132 into hippocampal neurons enhanced

89 Introduction of miR-200c into hPMR1-expressing cells red

90 Introduction of hydrophilic residues into HR2P results i

91 Lentiviral introduction of E4ORF1 into human PECs (E4ORF1(+) ECs) i

92 Introduction of F157L into human NKX2.5 substantially re

93 Unexpectedly, introduction of plexin B1 into human melanoma cell lines

94 f the exposures responsible for the sporadic introductions of MERS-CoV into human populations is urge

95 Importantly, the introduction of RDDs into IL12RB1 mRNAs negatively regul

96 The introduction of molecular devices into integrated circui

97 Furthermore, the introduction of PDEF into invasive breast cancer cells l

98 eplication but influences hepatotropism, and introduction of R194K into JHM.SD promotes replication i

99 Targeted introduction of this allele into K562 erythroleukemia ce

100 Recombinant viruses were reconstituted by introduction of these mutations into KSHV bacterial arti

101 cleases allows for the efficient and precise introduction of genetic change into livestock genomes.

102 The introduction of new reactivity into living organisms is

103 Introduction of N283 into LN40 (T283N) conferred efficie

104 Stable introduction of EphA2 into low-expressing cell lines enh

105 analyses of A(H1N1)pdm09 suggested multiple introductions of the virus into Madagascar, no antigenic

106 Introduction of ERbeta into MCF-7 cells reverses tamoxif

107 Conversely, the introduction of TRIM29 into MCF7 cells caused reversion

108 ty of natural products, we reasoned that the introduction of halides into medicinal plant metabolism

109 Introduction of these substitutions into Merlin dramatic

110 Introduction of functionalized mesopores into microporou

111 Importantly, introduction of either into mouse cortex promotes blood-

112 ctional human PERV receptors and proved that introduction of these into mouse fibroblasts allowed the

113 Strikingly, introduction of GLUD2 into murine glioma progenitor cell

114 Moreover, introduction of Symbiodinium into naive Aiptasia larvae

115 a source of fluorinated building blocks for introduction of fluorine into natural-product scaffolds.

116 thogens across international borders, or the introduction of diseases into new areas.

117 . Typhi populations and help identify recent introductions of S. Typhi into new or previously endemic

118 Furthermore, introduction of Bcr-abl into non-CML cells inhibits the

119 Introduction of saxCAB genes into non-host strains enabl

120 Significantly, stable introduction of E1A-12 into nontumorigenic Ad5-transform

121 The introduction of activin A into normal muscle increased t

122 lite markers and assignment tests revealed 2 introductions of the rockweed into Nova Scotia: 1 from G

123 entrations in the reaction mixtures and that introduction of these mutations into nsP4 and the promot

124 and the geographic origins of post-European introductions of paper mulberry into Oceania.

125 The introduction of modifications into oligonucleotides is i

126 The regioselectively controlled introduction of chlorine into organic molecules is an im

127 uorination chemistry, methods for the direct introduction of fluoroalkyl-groups into organic molecule

128 ctroporation is a powerful technique for the introduction of genes into organisms.

129 survival might be because of the inadvertent introduction of pCMV into our alpha1,3-galactosyltransfe

130 In addition, introduction of this gene into P. aeruginosa PAO1 confer

131 Introduction of ARF into p53 and ARF-null human colon ca

132 such vectors is problematic, however, as the introduction of SIN vectors into packaging cells cannot

133 CRISPR-Cas9-mediated introduction of pfcpsf3 mutations into parental lines re

134 Introduction of miR-449a into PC-3 prostate cancer cells

135 Re-introduction of AP-2alpha into PECAM1(+) tumour cells re

136 Introduction of aza-residues into peptide sequences may

137 that population immunity may not prevent the introduction of human viruses into pigs, and possibly vi

138 pulation immunity is unlikely to prevent new introductions of human IAV into pigs or vice versa, rein

139 s on the methods currently available for the introduction of multiple transgenes into plants and the

140 We report the introduction of PAs into plants by combined expression o

141 iological approaches to demonstrate that the introduction of a charge into pore lumen of MscL does in

142 e past approximately 5 years that led to the introduction of these catalysts into practical applicati

143 erric nontronites was observed following the introduction of Fe(II) into predominantly-Fe(III) octahe

144 ions or following the natural or intentional introduction of the virus into previously unaffected are

145 Furthermore, introduction of Cre recombinase into primary cortical cu

146 Introduction of mutant IDH1 into primary human astrocyte

147 Following the introduction of nonsense codons into promoter-proximal g

148 onjunction with techniques for site-specific introduction of aldehydes into proteins, the Pictet-Spen

149 e a technology, based on the cotranslational introduction of azide groups into proteins and the chemo

150 This methodology should facilitate the introduction of biological probes into proteins for cell

151 ically modified amino acids are used for the introduction of bioorthogonal handles into proteins.

152 The introduction of disulfide bonds into proteins creates ad

153 Introduction of disulfide bonds into proteins entering t

154 Introduction of PpPS into PS-deficient mouse embryonic f

155 e clean genome assemblies and to prevent the introduction of contamination into public databases, con

156 nsion of the outbreak in Brazil and multiple introductions of outbreak strains into Puerto Rico, Hond

157 arly, these effects were not noted following introduction of mutant IDH1 into Ras-transformed cells o

158 Introduction of MMP-1 into RGP melanoma cells induced ge

159 Introduction of caspase-8 into RPE cells may be a potent

160 Introduction of tviA into S. enterica serotype Typhimuri

161 Introduction of exogenous transposons into schistosomes

162 Whereas previous papers have studied the introduction of cement colloids into sediments, this stu

163 The unavoidable introduction of defects into silicon during the implanta

164 to interpret responses of water chemistry to introduction of CO2 into six water-rock batches with sed

165 Furthermore, the introduction of nahG into siz1, which reduces SA accumul

166 Introduction of SWP cDNA into smp(epi) plants fully rest

167 tem cells (iPSCs) usually involves the viral introduction of reprogramming factors into somatic cells

168 n Soweto, Johannesburg, before and after the introduction of rotavirus vaccine into South Africa's na

169 Introduction of SRF-S162D into SRF null ES cells permitt

170 Introduction of miR-27b into ST14-expressing cells did n

171 ts, combinatorial strategies, vector design, introduction of therapeutics into stem cells and enrichm

172 Stable introduction of active PTK6 into SYF cells also resulted

173 Introduction of PTK6 into SYF cells sensitized these cel

174 Introduction of GATA1s into Tc1 mice resulted in a syner

175 Introduction of TERT mutants into telomerase-deficient c

176 a favorable protein conformation and by the introduction of a cavity into the fully ligated active s

177 The most common strategy is the introduction of a frameshift into the open reading frame

178 FEN1 activity than removal of the 5'-flap or introduction of a hairpin into the 5'-flap structure.

179 These phenotypes are lost by the introduction of a mutation into the p300 binding domain

180 Here, we investigate the introduction of Ag nanoparticles into the core/shell str

181 de-cross-linking protocol for more effective introduction of antibodies into the gel layer.

182 s important human and animal pathogen to the introduction of antimicrobial agents into the clinical e

183 e villages, one relocated to accommodate the introduction of Asiatic lions into the sanctuary (n = 24

184 Introduction of Asn into the PqsC active site led to sig

185 the Central and South American isolates with introduction of B. pseudomallei into the Americas betwee

186 in spatial proximity, resulting in regional introduction of base J into the DNA.

187 PURPOSE OF REVIEW: Since the introduction of biologic therapies into the treatment pa

188 lds a defective virus; however, simultaneous introduction of both mutations into the heterologous Tat

189 ngth of the group attached to C20 and by the introduction of branching into the side chain.

190 However, the introduction of bulky residues into the amino acid bindi

191 cellular Ca(2+) evoked Ca(2+) influx upon re-introduction of Ca(2+) into the extracellular buffer.

192 Introduction of Ca(2+) into the nanochannels induces mit

193 This tutorial review could serve as an introduction of cardanol into the world of soft nanomate

194 migratory phenotype, which suggests that the introduction of cell motility into the model changes the

195 In contrast, introduction of changes into the muNS C-terminal region,

196 Briefly, the introduction of charges into the MscL pore lumen gates t

197 Following introduction of conidia into the lung, microarray analys

198 o evidence of this mechanism in AM following introduction of conidia into the mouse lung using transc

199 Introduction of Cys residues into the region between res

200 Moreover, the introduction of D410E into the D451E background resulted

201 ilized in the hydrogel, partitioning hinders introduction of detection antibody into the gel and, con

202 In contrast, introduction of diaromatic substituents into the 4-posit

203 -3-phenylpropanoic acids, resulting from the introduction of different substituents into the biphenyl

204 The recent introduction of disability measures into the England&Wal

205 on of the host response occurs both with the introduction of elementary bodies into the host and earl

206 ferase inhibitors and accelerate the pace of introduction of epigenetic therapies into the clinic.

207 films were more intense, indicating that the introduction of essential oil into the film matrix induc

208 ered following treatment with HA, and (3) if introduction of exogenous HA into the lens capsule promo

209 otomography sample preparation including (i) introduction of fiducial markers into the sample and (ii

210 Via introduction of flexibility into the inhibitor structure

211 we detected actin patches in the cell after introduction of fluorescent phalloidin into the medium,

212 de; however, this can be counter-balanced by introduction of fluoride into the framework to raise the

213 The introduction of fluorine into the structure of pharmaceu

214 the angle of incidence usually requires the introduction of gain media into the system.

215 tate on dimer-bending is investigated by the introduction of gamma-phosphate into the beta-tubulin to

216 hodologies for DNA sequencing has led to the introduction of genetic studies into the clinical realm.

217 In Kenya, introduction of Hib vaccine into the routine childhood i

218 Candidate lesions were tested by introduction of homologous changes into the Synechocysti

219 The controlled introduction of impurities into the crystal lattice of s

220 More recently, the introduction of intravital imaging into the GC field has

221 its low-pressure counterpart, owing to soft introduction of ions into the mobility cell with minimal

222 (iii) The introduction of lysine into the AC has little effect on

223 The introduction of methyl groups into the acridine ring cau

224 operties of ICP22 and ICP22 mutants prior to introduction of mutant genes into the viral genome.

225 Furthermore, introduction of mutations into the H10 receptor-binding

226 directed to an orthogonal mRNA, allowing the introduction of mutations into the large subunit that re

227 Introduction of mutations into the lower site had no eff

228 step impaired by antiretroviral agents or by introduction of mutations into the probe sequences requi

229 provides an extremely rapid approach for the introduction of mutations into the structural genes of W

230 We found that the introduction of mutations into the WUS-box of STF (STFm1

231 The introduction of nano-technology into the industry may re

232 Central to the method is the introduction of nanopores into the organic semiconductor

233 mechanism to overcome this problem and allow introduction of Ni into the atmosphere during eruption o

234 These results showed that the introduction of nickel into the carbonized wood improves

235 Ab initio calculations suggest that introduction of nitrogen into the aromatic system of the

236 Genetic therapies have attempted introduction of nucleic acids into the mitochondrion, nD

237 The introduction of O2 into the catechol degradation system

238 ases in the membrane potential are seen upon introduction of OXPHOS substrates into the nanofluidic c

239 The introduction of oxygen into the cell shifted the OCP to

240 ass spectrometer was undertaken to allow the introduction of ozone into the high-pressure trapping io

241 The introduction of paper into the microfluidic device for L

242 Introduction of PDE6 residues into the background of the

243 efficiency was probed through the controlled introduction of photoinactive conjugates into the assemb

244 Introduction of point mutations into the hnRNP A1-bindin

245 Introduction of point mutations into the mapped BPS led

246 ic and gene targeting approaches, as well as introduction of polymorphisms into the mouse genome.

247 c interface redesign strategy has led to the introduction of positive charges into the vicinity of th

248 However, introduction of Pro residues into the leader peptide str

249 Then, introduction of PSA antigen, into the anti-PSA immobiliz

250 f class 1 resistance integrons (RIs) and the introduction of Pseudomonas spp. into the bacterial comm

251 Following the introduction of PSS1 into the soybean cultivar Williams

252 us reaches the ER and can be bypassed by the introduction of Py DNA into the cytosol.

253 The first is the introduction of random errors into the genome by the vir

254 Computer-controlled ballistic introduction of reactant droplets into the levitated dro

255 ogical consequences that occur in mice after introduction of ricin into the pulmonary system.

256 We present evidence for the recent introduction of rok into the B. subtilis-Bacillus lichen

257 Introduction of rotavirus vaccines into the world's poor

258 Following introduction of RV1 into the national immunization progr

259 In vivo, the introduction of sHz into the peritoneal cavity produces

260 s in which starch turnover is occurring, and introduction of starch synthesis into the cytosol.

261 The introduction of steric clashes into the siderophore stru

262 Introduction of structural defects into the array by cou

263 uble bond, allows the highly stereoselective introduction of substituents into the alpha-position of

264 By contrast, introduction of T215F into the D67N/K70R/K219Q backgroun

265 864 submarine sunk during WWII and potential introduction of that Hg into the marine food chain have

266 An intubation attempt was defined as the introduction of the laryngoscope into the patient's mout

267 1/D1 West population argues against a recent introduction of the pathogen into the UK, but rather sug

268 g that increased dynamic freedom accompanies introduction of the protein into the biofilm state.

269 The introduction of these changes into the parental virus co

270 B N216S and NS5A C465S) were identified, and introduction of these mutations into the chimera rescued

271 The introduction of these residues into the rat beta1 distal

272 Introduction of this mutation into the biologically acti

273 Introduction of this polymorphism into the PB2 subunit o

274 addition to altering the particle shape, the introduction of TiF(4) into the synthesis results in TiO

275 genitor cells in vitro Consistent with this, introduction of TRBP into the mouse embryonic brain in u

276 Introduction of Trp residues into the Trp-devoid wild-ty

277 ole-derived alpha,beta-alkynyl ketones, (ii) introduction of various substituents into the alkyne fun

278 Introduction of various substituents into the alkyne fun

279 c variants of virus were identified, ongoing introduction of virus into the population helped perpetu

280 Introduction of vitamin D into the diet at weaning resul

281 Introduction of WIP into the patient's T cells restored

282 c and molecular clock analyses show a single introduction of ZIKV into the Americas, which we estimat

283 ences revealed between 24 and 33 independent introductions of H1N1/09 into the UCSD community, compri

284 Epidemiologic evidence of multiple introductions of infection into the population was subst

285 ly distinct lineages, indicative of multiple introductions of this virus into the city.

286 The results indicate that, despite multiple introductions of virus into the brain over the course of

287 and 2-hydroxyethyl methacrylate lead to the introduction of controlled degradability into these wide

288 Introduction of Fes into these lines with a recombinant

289 odels suggested several possible avenues for introduction of knots into these models, and these insig

290 On the introduction of NSCaTE into these channels, spatial Ca2+

291 neer vasculature in vivo has allowed for the introduction of instructions into tissues by genetically

292 t of TM3 with a secretory reporter domain or introduction of proline residues into TM3 changed the TM

293 ists face a major obstacle when planning the introduction of multigene traits into transgenic plants.

294 neck squamous cell cancer, particularly the introduction of biological agents into treatment paradig

295 Introduction of Gly770 into two dacomitinib-resistant EG

296 Here we found that introduction of trifluoromethyl groups into two differen

297 tocols have been achieved that permit facile introduction of s-tetrazine into unprotected peptides an

298 ommercial TOF-SIMS instrument permitting the introduction of surfaces into vacuum and SIMS analysis b

299 This novel system for AAV-mediated introduction of a mutation into wild-type mice has broad

300 Conversely, the introduction of excess Tbx5 into zebrafish embryos and m