ライフサイエンスコーパス: invader

1 atch between the invaded environment and the invader.

2 ing a competitive advantage in favour of the invader.

3 biological control agent, is now a worldwide invader.

4 invader-degrading Cas protein complex to the invader.

5 ricking neighboring cells into taking up the invader.

6 e site of Cas nucleases in the genome of the invader.

7 anism that must be navigated by the pathogen invader.

8 y of the soil microbiota and survival of the invader.

9 ion of multiple spacers that target the same invader.

10 hestrate effector responses to eliminate the invader.

11 invicta) aids the success of this prominent invader.

12 age often persists even after removal of the invader.

13 s and immunize the host against the matching invader.

14 f cells acquire short DNA sequences from the invader.

15 triggers rapid primed adaptation against the invader.

16 sproportionate increases in herbivory on the invader.

17 ify a cleavage site within the genome of the invader.

18 d microorganisms against diverse DNA and RNA invaders.

19 has devised strategies to sequester Mn from invaders.

20 atives based upon traits of the co-occurring invaders.

21 ffered as a reason not to manage troublesome invaders.

22 e in the coevolutionary arms race with their invaders.

23 mechanism for dealing with perceived foreign invaders.

24 en that grasses comprise the most aggressive invaders.

25 arks, and facilitates clearance of microbial invaders.

26 e response that effectively limits bacterial invaders.

27 nd use them to recognize and eliminate these invaders.

28 to recognize and eliminate potential fungal invaders.

29 diates innate immune responses to pathogenic invaders.

30 p crayfish such opportunistic and successful invaders.

31 r functions, serves to protect against viral invaders.

32 endogenous proteases and/or those of biotic invaders.

33 ve antibodies against potentially pathogenic invaders.

34 or engulfing and ultimately clearing foreign invaders.

35 otes from viruses and other potential genome invaders.

36 xygen species are produced to kill microbial invaders.

37 he genome from both pathogenic and parasitic invaders.

38 y on rapid changes in morphology to ward off invaders.

39 or use in recognizing and repelling pathogen invaders.

40 s in CRISPR arrays to defend against genetic invaders.

41 ost's CRISPR-Cas immune response against its invaders.

42 alls also act as barriers against pathogenic invaders.

43 may create a window of opportunity for these invaders.

44 against bacteria, viruses, and other foreign invaders.

45 gy to defend their cytosol against bacterial invaders.

46 uctions exceeded those induced by non-native invaders.

47 with different microbial pathogens and other invaders.

48 The Invader 1.0 assay (Invader HCV Genotyping Assay, version

49 ent study, we evaluated the compatibility of Invader 1.0 with the COBAS MONITOR (COBAS AMPLICOR HCV M

50 reduce establishment of a currently prolific invader (A. petiolata) throughout New England driven by

51 For unstructured invaders, a formula for this exponent can typically be w

52 individuals over time to identify trends in invader abundance and spatial extent.

53 The increased invader abundance in AM dominant forests can further fac

54 Manipulation of invader abundance revealed both thresholds and saturatio

55 ecological effects of native and non-native invaders across levels of biological organisations and r

56 llows for the presence of a larger number of invader alleles at the wave front, where effective popul

57 lied either green leaves of the allelopathic invader Alliaria petiolata, a nonsystemic fungicide to s

58 Invaders allocate more resources to reproduction than na

59 actions between the resident species and the invader along the resource availability gradient.

60 ors from a large number of bacteria or other invaders along a 2D layer of macrophages, providing an i

61 rom reductions in allelopathic traits in the invader and evolution of tolerance in the native.

62 determined lambdac and lambdaper-year of the invader and of a common native, Trillium erectum.

63 interface, and width of the interface (where invader and resident compete directly) should increase a

64 The match between the invader and the existing native community may explain wh

65 es, the match between characteristics of the invader and those of members of the existing native comm

66 scanning the vascular surface for potential invaders and collecting deposited bacteria.

67 ant ungulates enhance demographic success of invaders and depress natives' success, with broad implic

68 crRNAs) that include sequences captured from invaders and direct CRISPR-associated (Cas) proteins to

69 ng the cytoplasm for traces of intracellular invaders and endogenous stress signals.

70 her-connectance food webs tend to host fewer invaders and exert stronger biotic resistance compared t

71 derstanding competitive interactions between invaders and functionally similar native species provide

72 In contrast, consumption by the invaders and higher predator remained additive.

73 resources can create niche opportunities for invaders and highlight the need for additional long-term

74 by capturing short DNA sequences from these invaders and integrating them into the CRISPR locus of t

75 bodies protect the host against both foreign invaders and its own damaged/apoptotic cells.

76 Invaders and natives were themselves equally susceptible

77 ense: They internalize and destroy microbial invaders and produce signals that trigger other immune r

78 ve mechanisms designed to neutralize foreign invaders and resolve injury.

79 and eliminating danger arising from foreign invaders and tissue trauma.

80 del provides a key element to forecast novel invaders and to extend pathway-level risk analyses to in

81 dered proteins and regions to fight flexible invaders and viruses and to successfully overcome the vi

82 The invasion dynamics of a structured invader are much more complicated but an analytic soluti

83 post-canopy environments suggest eastern US invaders are driving a seasonal redistribution of forest

84 Invaders are expanding worldwide and extreme drought eve

85 ISPR-associated) genes: sequence segments of invaders are incorporated into host genomes at CRISPR lo

86 ative and invasive forest species or whether invaders are more responsive to warming trends that have

87 tive competitor from areas with highly toxic invaders are more tolerant to competition from the invad

88 the immune response induced by the foreign "invader" are important factors in determining the capaci

89 adica sebifera (Chinese tallow tree, a major invader) arises from differences among habitats in spati

90 Our laboratory studies Invaders as an alternative approach toward this end.

91 ne response by detecting bacterial and viral invaders as well as endogenous stress signals.

92 of Haloferax volcanii using a plasmid-based invader assay.

93 ce may be particularly critical for stopping invaders at early life history stages, but new species c

94 To combat these invaders, bacteria possess an arsenal of defenses, such

95 e mycorrhizal type composition of understory invaders between AM and ECM dominant forests.

96 Established colonies can therefore resist invaders by outnumbering them.

97 ncile the discrepancy in diversity loss from invaders by showing that invaded communities have lower

98 Spread of a locally dispersing invader can become motion of an interface between the in

99 Invaders can escape type I-E CRISPR-Cas immunity in Esch

100 that controls the extent to which bacterial invaders can establish.

101 ive interaction and subsequent disruption of invaders' cell membranes.

102 In the absence of the higher predator, the invader consumed significantly more basal prey than the

103 erence to predator threat on the part of the invader contributes to its success and impacts within in

104 Thus, the impacts of the invader created a positive feedback early in the invasio

105 RISPR-derived RNA (crRNA), which directs the invader-degrading Cas protein complex to the invader.

106 fection, they incorporate short fragments of invader-derived DNA into loci called clustered regularly

107 CRISPR loci contain multiple short invader-derived sequences separated by short repeats.

108 d in prokaryotic genomes, which harbor short invader-derived sequences, and the CRISPR-associated (Ca

109 he type I effector helicase and nuclease for invader destruction, Cas3.

110 ied as the nuclease responsible for ultimate invader destruction, is also essential for adaptation.

111 eing riparian specialists, and that riparian invaders disperse in more ways, including by water and h

112 m this locus, and the degradation of cognate invader DNA (protospacer).

113 ence plays a role in the initial scanning of invader DNA for a match, before base pairing of the full

114 system built from capture and integration of invader DNA into CRISPR (Clustered Regularly Interspaced

115 fection by acquiring 'spacer' sequences from invader DNA into genomic CRISPR loci.

116 ses and plasmids, by specific degradation of invader DNA or RNA.

117 his model, RecG and Cas3 proteins respond to invader DNA replication forks that are blocked by Cascad

118 tion when responding to blocked or collapsed invader DNA replication.

119 Host immunity is based on incorporation of invader DNA sequences in a memory locus (CRISPR), the fo

120 In Escherichia coli, Cascade-Cas3 degrades invader DNA to effect immunity, termed 'Interference'.

121 king sequence information (PAMs) to identify invader DNA.

122 However, invaders do colonize resource-poor environments, and the

123 ns were found above 26.5 degrees N where the invader dominated the community.

124 ly, warming shifted the plant community from invader-dominated to native-dominated but only in the pr

125 We show that invaders drive scale-dependent biodiversity loss through

126 ng energy, and recognition experiments using Invader duplexes with different +1 interstrand zippers o

127 nomers have on the recognition efficiency of Invader duplexes.

128 phagocytes of Drosophila encounter bacterial invaders early in infection and contribute to survival o

129 es with a high catabolic similarity with the invader efficiently reduced the invader relative density

130 tions can resist invasion by all multichoice invaders, even while engaging in relatively little punis

131 ing tunable CRISPR immune response to combat invader evolution.

132 nd understory plants, whereas one understory invader excludes native species at the ground level.

133 der "novel weapons," only the initially rare invader exercises interference.

134 The invader exhibited stronger direct feeding and was also m

135 er productivity per unit leaf investment, as invaders exhibited both greater photosynthetic abilities

136 reater leaf construction and nitrogen costs, invaders exhibited greater instantaneous photosynthetic

137 emerge for a wide range of assumptions about invader fitness, competition dynamics, and network struc

138 his study will drive the design of efficient Invaders for applications in molecular biology, nucleic

139 Small RNAs target invaders for silencing in the CRISPR-Cas pathways that p

140 t it recently arrived in North America as an invader from Europe.

141 ia, as it acted as a corridor to the foreign invaders from Eurasia and Central Asia.

142 ISPR response against diversified or related invaders, giving microbes an advantage in the coevolutio

143 The invader growth was then examined as a function of reside

144 that native populations more tolerant to the invader had higher fitness when the invader was common,

145 al and restoration of habitat from which the invader has been removed, it is vital to quantify the im

146 preciated, quantifying the impacts of native invaders has important implications because human-assist

147 Invaders have been documented to modify fire regimes, al

148 comparative methods, we show that successful invaders have fast traits, such as large and frequent cl

149 Biological invaders have long been hypothesized to exhibit the fast

150 atural immune system to more easily decimate invaders, have gained attention as alternatives to broad

151 The Invader 1.0 assay (Invader HCV Genotyping Assay, version 1.0; Third Wave Te

152 traits generally associated with successful invaders (high growth rates, early reproduction and many

153 The Invader HPV (Inv2) test, by Third Wave Technologies, Inc

154 HC2) assay to that of a prototype Third Wave Invader human papillomavirus (HPV) (IHPV) analyte-specif

155 We examined how invader impacts on landscape structure influence native

156 Solidago canadensis is an aggressive invader in China.

157 a decrease in the competitive ability of the invader in species-rich vs. species-poor bacterial commu

158 has been shown to be nonmotile, to be a poor invader in vitro, and to be a poor colonizer of poultry

159 aea and bacteria by eliminating nucleic acid invaders in a crRNA-guided manner.

160 pests and to modulate responses to specific invaders in a time-of-day-dependent manner (gating).

161 CRISPR-Cas systems eliminate nucleic acid invaders in bacteria and archaea.

162 Our results indicate that woody understory invaders in ENA forests are not constrained to the same

163 her Type III systems, Cmr eliminates plasmid invaders in Pyrococcus furiosus by a mechanism that depe

164 measurements when assessing the impact of an invader, including density dependence, multifunctionalit

165 100 years have been colonized by any of the invaders investigated, despite offering climatically sui

166 These results suggest that this invader is developing evolutionary limits in its introdu

167 The transition from colonist to invader is especially enigmatic for self-incompatible sp

168 proposes that the demographic success of an invader is largely affected by the availability of resou

169 Furthermore, the predicted richness of invaders is 11%-18% significantly lower inside PAs than

170 ia and archaea from viruses and other genome invaders is hypothesized to arise from guide RNAs encode

171 the mechanism by which Cst complexes silence invaders is unknown.

172 ously identified as a defense against biotic invaders, is required for key ABA responses of guard cel

173 an organism against the myriad of microbial invaders it constantly confronts.

174 eptors (TLRs) detect molecular signatures of invaders known as pathogen-associated molecular patterns

175 Short DNA segments of the invader, known as spacers, are stored in the CRISPR arra

176 ponse, we propose that T. cruzi is a stealth invader, largely avoiding recognition by components of t

177 in's naturalization hypothesis predicts that invaders less related to native flora are more likely to

178 hairpins with similar efficiency as original Invader LNAs.

179 In 2005, we introduced Invader locked nucleic acids (LNAs), i.e., double-strand

180 bout the long-term dynamics of invasions; do invaders maintain their dominant status over long time s

181 y simple monomers will accelerate the use of Invader-mediated dsDNA recognition for applications in m

182 he performances of the Third Wave Technology Invader method and the Digene Hybrid Capture 2 assay to

183 -step sequential model in the presence of an invader mismatch.

184 st efficiently recognize the presence of the invader, mobilize cells to the site of infection, and de

185 the identification of two simpler classes of Invader monomers.

186 sponse is host protective to contain foreign invaders, much of today's pharmacopeia can cause serious

187 However, ultimately, successful invaders must have positive growth rates that longer ter

188 When invader mutation blocks this interference activity, Casc

189 ated (Cas) proteins to destroy corresponding invader nucleic acids.

190 nto effector complexes that destroy matching invader nucleic acids.

191 Dominance by exotic invaders occurs with moderate initial frequencies of exo

192 ple act of nutritional warfare, starving the invader of an essential element, is an effective means o

193 a lamprey (Petromyzon marinus), a vertebrate invader of the Laurential Great Lakes, that a synthesize

194 Surprisingly, invaders of deciduous forests show the same small-genome

195 sts show the same small-genome tendencies of invaders of more open habitats, supporting genome size a

196 Furthermore, the invaders' offspring follow a unique life-history strateg

197 Invaders often have greater rates of production and prod

198 re due to a proportionately larger effect of invaders on common species, suggesting that rare species

199 hat lead to AD are derived not from external invaders or amyloid but from oxidative damage of our own

200 of resident inflammatory cells by microbial invaders or endogenous ligands.

201 stion is: What is the probability that a new invader (or a new mutant) will take over a resident popu

202 set of DNA transposon families dubbed SPACE INVADERS (or SPIN) whose consensus sequences are approxi

203 ends on two factors: the covariances between invader parameters and resident populations and the shif

204 Importance: To contain invaders, particularly RNA viruses, plants have evolved

205 An invader plasmid assay showed that mutation either in the

206 is effective in triggering degradation of an invader plasmid carrying the matching protospacer sequen

207 he development and validation of a prototype Invader Plus method for the qualitative detection of her

208 Invader population growth rates were negative only at th

209 demonstrate that certain pseudocomplementary Invader probe designs result in very efficient and speci

210 The resulting ONs and Invader probes are characterized by thermal denaturation

211 Herein, we introduce pseudocomplementary Invader probes as a step in this direction.

212 Invader probes based on large intercalators efficiently

213 present study, we explore the properties of Invader probes based on larger intercalators, i.e., pery

214 Invader probes have been proposed as alternatives to pol

215 between pseudocomplementary DNA (pcDNA) and Invader probes, which are activated for mixed-sequence d

216 y to recognize and destroy virus and plasmid invaders, prokaryotic CRISPR-Cas systems capture fragmen

217 re we report proof-of-concept results for an Invader(R) assay-based genotyping procedure that can det

218 : a real-time measurement of the fluorescent Invader(R) signal and analysis with a specifically desig

219 this, we assessed the growth of a bacterial invader, Ralstonia solanacearum, when introduced into co

220 xotic recruitment following removal of adult invaders (reinvasion pressure) influences restoration ou

221 ity with the invader efficiently reduced the invader relative density, while at high resource availab

222 While the invader remained rare for two decades, a decline in gran

223 immune system defends the lung against these invaders remains unclear.

224 fficiently allocate a limited budget between invader removal and restoration of habitat from which th

225 Some fungal invaders reported here have been detected in other locat

226 Phagocytosis of microbial invaders represents a fundamental defense mechanism of t

227 Studying invader responses to disturbance can help us to understa

228 ies in ecosystems challenged by allelopathic invaders: RFS mutualism disruption drives carbon stress,

229 This is problematic because low invader richness can indicate invasion resistance by the

230 ribes an unbiased approach to this using the Invader RNA assay (Third Wave Technologies, Inc.) to qua

231 ctioning as a standalone RNase that degrades invader RNA transcripts, but the mechanism linking invad

232 Here we show that invader RNAs also activate the Cmr complex to cleave DNA

233 complex as a novel DNA nuclease activated by invader RNAs containing a crRNA target sequence and a rP

234 complex of the Type III-B Cmr system cleaves invader RNAs recognized by the CRISPR RNA (crRNA ) of th

235 functions by homology-dependent cleavage of invader RNAs.

236 t interference can significantly increase an invader's competitiveness, and its growth when rare, if

237 nvaded environment are key predictors of the invader's distribution.

238 The invader's fate in soil was determined in the presence of

239 ll CRISPR RNAs that are complementary to the invader's genome and specify the targets of RNA-guided C

240 ssive introgression of local alleles into an invader's genome.

241 Interference never enhances a rare invader's growth in the homogeneously mixing approximati

242 niche divergence, which would facilitate the invader's integration into the community and their coexi

243 d both interface width and the most advanced invader's lead scaled with front length.

244 on-native prey displace native prey, then an invader's net influence should depend on both its abunda

245 That is, interference can increase an invader's success when colonization of open sites depend

246 ptive traits are important in determining an invader's success.

247 are reached, specific receptors bind to the invader's surface, initiating phagocytosis, phagosome fo

248 r RNA transcripts, but the mechanism linking invader sensing to Csm6 activity is not understood.

249 partial Csa (Type I-A) module (lacking known invader sequence acquisition and crRNA processing genes)

250 with CRISPR-Cas immune systems capture short invader sequences within the CRISPR loci in their genome

251 d the relative location of the most advanced invader should each scale with interface length.

252 The increased litter quantity and quality of invaders should increase nutrient cycling through faster

253 heir genomic CRISPR arrays for use in future invader silencing.

254 valuated as a function of dispersal rate and invader source region relative to a control without nati

255 ects of invasion and impacts associated with invader source region.

256 invasibility relationship that was robust to invader source region.

257 climate change may decrease the barriers to invader species' spread.

258 terized two hAT elements, TcBuster and Space Invaders (SPIN), that are members of a recently describe

259 cate that a single base pair mismatch in the invader stalls branch migration and displacement occurs

260 e was found as the main determinant of plant invader success (i.e., establishment, growth, and flower

261 esting that competition is the main limit on invader success at low elevations, as opposed to low-gro

262 short fragments of DNA (mainly from foreign invaders such as viruses and plasmids) and subsequent de

263 immune systems that protect prokaryotes from invaders such as viruses and plasmids.

264 iated), to provide resistance against mobile invaders, such as viruses and plasmids.

265 rs are more tolerant to competition from the invader, suggesting coevolutionary dynamics between the

266 sident species became more important for the invader suppression.

267 QS were less effective at defending against invaders targeted by any of the three CRISPR-Cas systems

268 n the repeat sequences to release individual invader targeting RNAs.

269 er adjacent motif (PAM) that is critical for invader targeting.

270 effector complex that is comprised of small invader-targeting RNAs from the CRISPR loci (termed prok

271 leotide CRISPR repeat sequence tag 5' of the invader-targeting sequence.

272 resistance depends on latitude, habitat and invader taxon, in addition to distinguishing between com

273 zoic temperate zones evidently received more invaders than the tropics or poles, but this dynamic cou

274 ral principles for the optimal control of an invader that damages its environment.

275 , Drosophila suzukii (Matsumura) is a recent invader that infests intact ripe and ripening fruit, lea

276 ut labile litter, whereas the soils under an invader that input labile litter (kudzu, Pueraria lobata

277 pend on any intraspecific differences of the invader that may alter establishment success.

278 ess in a glasshouse experiment with a forest invader that produces known anti-fungal allelochemicals.

279 S. aureus (MRSA) is a potential bloodstream invader that requires aggressive antimicrobial treatment

280 e new asexual lineages really those powerful invaders that could quickly displace their sexual ancest

281 fungal symbionts (RFSs) for soil resources, invaders that disrupt plant-RFS mutualisms can significa

282 NAs) contain sequence elements acquired from invaders that guide CRISPR-associated (Cas) proteins bac

283 vailability most benefits another aggressive invader, the nitrogen-fixing tree Morella faya.

284 he functions that are most often affected by invaders; the relationships between changes to ecosystem

285 tects bacteria and archaea from nucleic acid invaders through an RNA-mediated nucleic acid cleavage m

286 e there are fewer resources available for an invader to use.

287 postintroduction phenotypic changes may help invaders to compensate for reductions in adaptive potent

288 ems function by acquiring genetic records of invaders to facilitate robust interference upon reinfect

289 rstanding of how postintroduction changes in invader traits affect invasion processes.

290 Plants perceive microbial invaders using pattern recognition receptors that recogn

291 Plants can detect invaders via the recognition of pathogen-associated mole

292 t to the invader had higher fitness when the invader was common, but these traits came at a cost when

293 e generally decreased as the mismatch in the invader was encountered earlier in displacement.

294 on, but these traits came at a cost when the invader was rare.

295 We found that the relative density of the invader was reduced by increasing resident community ric

296 The impacts of native invaders were primarily manifested at the individual lev

297 ce against the competitive effects of strong invaders, which likely promoted their persistence in inv

298 latory mechanisms that eliminate these nasty invaders while also constraining collateral damage to vi

299 gle species may inadvertently create harmful invaders with high adaptive potential.

300 must distinguish self from non-self to repel invaders without inducing autoimmunity.