ライフサイエンスコーパス: invariable

1 nsition to a "castration-resistant" state is invariable.

2 tasis and, until recently, was thought to be invariable.

3 currences in bortezomib-treated patients are invariable.

4 stituted by glutamate, but E63 appears to be invariable.

5 secondary structure features remained nearly invariable.

6 gles is likely influenced by the more rigid, invariable 3' and 5' flanking TT dinucleotide steps and

7 1*08, the transmission of DRB1*15 was almost invariable (37 transmissions to one non-transmission).

8 n of adenine by 2-amino purine (2-AP) at the invariable A small middle dotT base pair at the -11 posi

9 neural tube and lens vesicle [2]; PCD is an invariable accompaniment to these processes, but it is u

10 y 3 and approximately 1.7, respectively, but invariable action spectra and effective antenna sizes of

11 +) due to a direct contact from the N7 of an invariable adenosine.

12 Posterior leaflet tethering is invariable after mitral annuloplasty, rendering postoper

13 Deletion of invariable amino acid residues in a conserved domain of

14 Despite having almost invariable amino acid sequences in their principal DNA-b

15 nts of MacRPA3 by replacing each of the four invariable amino acids in the zinc finger with alanine.

16 lectins share a common sequence motif of 14 invariable and 18 highly conserved aa residues known as

17 49.7mg/l); whereas phenolic content remained invariable and ascorbate content peaked near S5 in both

18 us critical illness polyneuropathy is almost invariable and can be found up to 5 yrs after intensive

19 delta, epsilon, and zeta subunits, which are invariable and ensure signal transduction.

20 fection by Mycobacterium tuberculosis is not invariable and may depend on bacillary as well as host f

21 this, herpes simplex virus 1 (HSV-1) causes invariable and rapid lethality in STING-deficient (STING

22 (variable and flexible) with the C-terminal (invariable and rigid) parts of the Ca2+-binding loop.

23 Using this feature, we found that invariable and variable epigenetic states across cell ty

24 Furthermore, mutation of the invariable aspartic acid to asparagine in VEGFR-2 lowere

25 This revealed an invariable association of perifascicular atrophy with ca

26 only three positions where the amino acid is invariable between all the predicted proteins.

27 erated by either deleting or substituting an invariable C-terminal Ile(316), wedged into a hydrophobi

28 pes, but heterozygous pups used individually invariable call sequences with less complicated call typ

29 This two- to threefold invariable CAP stimulation appears to depend on the -45

30 OCT has allowed us to demonstrate the almost invariable coexistence of the bursa premacularis and spa

31 sive proteins, act redundantly to ensure the invariable combination of L1 and L2 postsynaptic element

32 with kinetics of binding that are relatively invariable compared to HH26, which is highly specific an

33 RESISTANT6 (AXR6), which encodes CULLIN1, an invariable component of the SCF complex.

34 SCF complexes consist of three invariable components, Skp1, Cul-1 (Cdc53 in yeast) and

35 Thus, the nucleosomal response is an invariable consequence of ERK and p38 but not JNK/SAPK a

36 ystemic inflammatory states and is an almost invariable consequence of septic shock.

37 cid receptor alpha) haploinsufficiency is an invariable consequence of t(15;17)(q22;q21) translocatio

38 ogressive reduction in firing rate is not an invariable consequence of the fatigue associated with su

39 Purely invariable CpGs display a bimodal distribution with enri

40 f instead of ELR (Glu-Leu-Arg) preceding the invariable CXC motif.

41 in that carries the additional loop KSGKPLH, invariable cysteine (Cys) residues Cys-40 and Cys-168, a

42 this peptide, indicating that the C-terminal invariable domain is immunodominant.

43 oduced the entire sequence of the C-terminal invariable domain of VlsE from B. burgdorferi strain B31

44 oduced the entire sequence of the C-terminal invariable domain of VlsE was conjugated to the carrier

45 We concluded that the C-terminal invariable domain was exposed at the antigen's surface b

46 spirochetes, indicating that the C-terminal invariable domain was exposed at the antigen's surface.

47 Mouse antibody to the C-terminal invariable domain was not able to confer protection agai

48 and antigenic conservation of the C-terminal invariable domain were assessed.

49 VlsE contains two invariable domains and a variable one that includes six

50 It is not known if these two invariable domains are exposed at the surface of either

51 gen of Borrelia burgdorferi, consists of two invariable domains at the amino and carboxyl termini and

52 ntigen of Borrelia burgdorferi, contains two invariable domains located at the amino and carboxyl ter

53 munodominant variable domain and one or more invariable domains that are not antigenic.

54 irochete, Borrelia burgdorferi, contains two invariable domains, at the amino and carboxyl termini, r

55 spirochete, also contains both variable and invariable domains.

56 propagating ruptures are largely similar and invariable during the rupture process regardless of the

57 ly robust; their expression is controlled by invariable expression programs.

58 Eosinophilia is a common, but not invariable, feature of these diseases.

59 t activation and microthrombus formation are invariable features of xenograft rejection and the vascu

60 Hypofrontality is a common but not invariable finding in schizophrenia.

61 ell requirement for these interactions is an invariable finding, however, is less clear.

62 evealed a 2.9-Mb region that was essentially invariable for all 31 8.1 AHs.

63 ticulum from building blocks that include an invariable glycerol backbone and variable fatty acyl cha

64 er of intragenic recombination events nearly invariable in a given population, suggesting that the re

65 Intractable seizures are invariable in children with ISOD; however, to our knowle

66 hromosome, believed to be nonrecombining and invariable, is a classic example of the effect of natura

67 pathophysiology of sepsis that includes the invariable loss of the host's microbiome with the emerge

68 ype XA21 and the kinase-dead mutant with the invariable Lys736 residue mutated to glutamic acid were

69 mice resulted in respiratory dysfunction and invariable neonatal death, related to the complete absen

70 rom a single point mutation, which alters an invariable nucleotide in the splice donor site after exo

71 kemia cells, a G1 arrest is a common, if not invariable, occurence and takes place after the appearan

72 An important caveat is the invariable occurrence of GVHD that precludes long-term s

73 e neutral theory where most sites are either invariable or neutral.

74 infrared spectra of TiO(2)-adsorbed OFX were invariable over a wide concentration and pH range and we

75 als form tetrad synapses that incorporate an invariable pair of postsynaptic elements, one each from

76 osition and cognitive dysfunction, which are invariable pathological features in patients with Alzhei

77 As cerebral amyloid angiopathy is an almost invariable pathological finding in Alzheimer's disease,

78 for approximately 12 h, and then display an invariable pattern of migration to distinct regions of t

79 Each single mutation at an invariable position resulted in a protein containing les

80 proteins harboring a mutation at one of the invariable positions bound to single-stranded DNA weakly

81 of protein structure, mutations at the other invariable positions led to larger structural changes.

82 However, with the nearly invariable progression of this disease to androgen indep

83 ia, is characterized by its insidious onset, invariable progression to chronic renal failure and a st

84 ynthetic peptide (C(6)), based on the 26-mer invariable region (IR(6)) of the variable surface antige

85 Invariable region (IR)(6), an immunodominant conserved r

86 the full-length dbpA gene combined with the invariable region 6 of the vlsE gene (DbpA/C6) and (b) t

87 rabbit antibody raised against the conserved invariable region 6 of VlsE, as assessed by indirect imm

88 peptide (C6) that reproduces the sequence of invariable region 6 of VlsE, the antigenic variation pro

89 ked immunosorbent assay antigens to map this invariable region in infected monkeys, mice, and human L

90 In contrast, antibody to the more conserved invariable region IR(6) of VlsE was present in all of th

91 Only one invariable region, IR(6), was antigenic in all animals o

92 contains a 26-amino-acid-long immunodominant invariable region, IR(6).

93 ithin the VlsE variable domain there are six invariable regions (IR1-6) that together amount to half

94 iable one that includes six variable and six invariable regions (IRs).

95 for an antibody response to each of the six invariable regions (IRs; i.e., IR(1) to IR(6)) of VlsE,

96 Short, nonantigenic, invariable regions also may be present within the variab

97 resent study, the antigenicity of all of the invariable regions in B. burgdorferi-infected monkeys, h

98 Surprisingly, unlike the invariable regions of variable major protein, variant su

99 The latter contains six invariable regions, IR(1) to IR(6), and six variable reg

100 Leu349 was another invariable residue.

101 B. germanica GST contained 18 of the 26 invariable residues identified in mammalian GST by x-ray

102 -shift conservation between fibrils revealed invariable secondary-structure properties, however, with

103 ds allowing for intersite rate variation and invariable sites confirms that centrohelid heliozoa are

104 This invariable stimulation is by two- to threefold and occur

105 nition site and the nuclease active site are invariable, suggesting potential targets for antivirals

106 Cys111 is the invariable third half-cystine of the second complement c

107 le thresholds persist longer than those with invariable thresholds because inactive workers perform t

108 rt wavelength band (460 nm) was found almost invariable throughout the titrations.

109 l to incorporate other risk factors, and are invariable to patient preference.

110 r alone or in collaboration with ECNA) is an invariable trigger of paroxysmal atrial tachyarrhythmias

111 ostly in numerous ways of extensions from an invariable trimannosyl core and terminal modifications.

112 phasic response to glucose were essentially invariable up to passage 38 but thereafter declined.

113 he plasma membrane proteome remained largely invariable, we observed pronounced alterations in severa

114 ro-adapted rabbit and dog BSE agent remained invariable with respect to the original cattle BSE prion