ライフサイエンスコーパス: invasive potential

1 ors with high TF, supporting their increased invasive potential.

2 nt and IBC, representing lesions with a high invasive potential.

3 f second-tier genes led to a similar loss of invasive potential.

4 cancers and contributes importantly to their invasive potential.

5 orage-independent growth, and a reduction in invasive potential.

6 eages have appreciably greater virulence and invasive potential.

7 ssue that relates to their proliferative and invasive potential.

8 ngitis is a major reservoir for strains with invasive potential.

9 ptosis of the GBM(R) cells and reduced their invasive potential.

10 prostate cancer sublines that vary in their invasive potential.

11 d that associated directly or inversely with invasive potential.

12 roliferative ductal alveolar outgrowths with invasive potential.

13 M and M-related proteins and increased skin-invasive potential.

14 ns has been shown to directly correlate with invasive potential.

15 like activity that might contribute to their invasive potential.

16 is a human-specific bacterium that varies in invasive potential.

17 cellular environment, ultimately attenuating invasive potential.

18 (-)), which also shows the greatest in vitro invasive potential.

19 hereas downregulation enhances migratory and invasive potential.

20 1/2 in all cell lines and in those with high invasive potential.

21 following ionizing radiation, and increased invasive potential.

22 ) signaling to enhance tumor cell growth and invasive potential.

23 ion to estimate changes in serotype-specific invasive potential.

24 n, signaling pathways, and the morphological invasive potential.

25 es the formation of multifocal tumors of low invasive potential.

26 l population with anchorage independence and invasive potential.

27 paB, Akt, ERK2, Tyk2, and PKC to reduce TNBC invasive potential.

28 eased Gab2-mediated tumor cell migration and invasive potential.

29 competence, growth factor independence, and invasive potential.

30 ges concomitant with increased migratory and invasive potential.

31 PA in LRP-deficient clones, attenuated their invasive potential.

32 ed with gemcitabine resistance and increased invasive potential.

33 -cell contacts and enhance cell motility and invasive potential.

34 ssion or high tissue cohesion showed limited invasive potential.

35 in tumor characteristics including increased invasive potential.

36 ponses to C. albicans strains with different invasive potentials.

37 PGE(2) also increased cellular migratory and invasive potentials.

38 romoter activity, and cellular migratory and invasive potentials.

39 on 2-fold in a wound healing assay and their invasive potential 3-fold in a transwell invasion assay.

40 ant change was detected in serotype-specific invasive potential after PCV7 introduction.

41 ce of disease caused by serotypes with lower invasive potential and among individuals with low levels

42 e chick chorioallantoic membrane lack tissue-invasive potential and fail to induce angiogenesis.

43 OCK/ARHGAP25 signaling pathway promotes ARMS invasive potential and identify these proteins as potent

44 d aggressiveness with enhanced migration and invasive potential and mesenchymal phenotypes.

45 n front, allowing for both quantification of invasive potential and molecular characterization of inv

46 ression through G(1) and inhibit the growth, invasive potential, and clonogenic ability of these pros

47 s in anchorage-independent growth, increased invasive potential, and the formation of a transformatio

48 cancer cells with the highest migratory and invasive potential are five times less stiff than cells

49 volved in tumor proliferation, survival, and invasive potential are in complex with PU-H71-bound Hsp9

50 ty to form colonies in soft agar and reduced invasive potential as tested in a matrigel in vitro inva

51 provide a novel perspective on the enhanced invasive potential associated with MSLN and MUC16 co-ove

52 sing variations in complement resistance and invasive potential between capsular serotypes.

53 h abrogated the effect of PGE(2) on cellular invasive potential but not on cellular migratory potenti

54 Several microbial pathogens augment their invasive potential by binding and activating human plasm

55 overexpression in oral SCCs decreases their invasive potential by diminishing migratory capability.

56 ostaglandin E(2) (PGE(2)) increases cellular invasive potential by inducing matrix metalloproteinase-

57 oximal to the stroma could lead to increased invasive potential by inducing novel or better interacti

58 n three uveal melanoma cell lines of various invasive potential by real-time PCR.

59 man leukemic TALL-1 cells reduces their high invasive potential, by decreasing the expression of the

60 n p53, decrease in v-myc and Bcl-2) and anti-invasive potential (decrease in integrin alpha3) of the

61 rfering RNA resulted in an increase in their invasive potential, downregulation of E-cadherin and inc

62 ns in promoting tumor cell proliferation and invasive potential due to increased complex formation as

63 s of nontypeable H. influenzae may have more invasive potential, especially in young children and pat

64 targeted against angiogenesis and tumor cell invasive potential form a new class of investigational d

65 ase screen for cancer cell deformability and invasive potential in a high-throughput microfluidic chi

66 MPs, VEGF and MCP-1 genes, and increased the invasive potential in A549 cells.

67 RIE-Tr cells demonstrated TGF-beta-dependent invasive potential in an in vitro assay and were resista

68 rmore, ZEB1 blockade decreases migratory and invasive potential in ARCaP(M) compared with the control

69 LOXL2 showed the strongest association with invasive potential in both highly invasive/metastatic br

70 ponsible for the correlation between MDR and invasive potential in cancer cells.

71 R2 or Src attenuated LDH activity as well as invasive potential in head and neck cancer and breast ca

72 A_100338 and miR-141-3p in the regulation of invasive potential in liver cancer cells.

73 TNCEGFL-expressing melanoma cells had higher invasive potential in Matrigel invasion assays, with cel

74 expression has been correlated with enhanced invasive potential in multiple tumor models.

75 hibition may represent a strategy to inhibit invasive potential in pancreatic cancer.

76 and radiation-induced apoptosis and reduced invasive potential in the GBM(S), but not in the GBM(R),

77 , features that were associated with greater invasive potential in three-dimensional cultures in vitr

78 e in invasive cells greatly diminished their invasive potential in vitro as did blocking TGF-beta sig

79 TNBC cells, augments TNBC cell migratory and invasive potential in vitro, and enhances tumorigenicity

80 cancers and has been shown to control their invasive potential in vitro, we aimed to assess the impl

81 ssion in their proliferation, migration, and invasive potential in vitro.

82 kout PDAC cells, correlating with their poor invasive potential in vivo.

83 cells display markedly higher migratory and invasive potentials in vitro, which are blocked by inhib

84 l proliferation (IGF2, FOS, JUN, cyclin D1), invasive potential (MMP1, ATF3), survival (A20, NFkappaB

85 ship can be drawn between morphology and the invasive potential of a fungus.

86 In the present study, we investigated the invasive potential of a noninvasive, CSF-1R-negative, mo

87 provide a powerful framework to evaluate the invasive potential of a species in nitrogen-limiting eco

88 hat MEK and BRAF inhibitors can increase the invasive potential of approximately 20% of human melanom

89 Moreover, the invasive potential of ARMS cells depended on ROCK activi

90 erin expression contributes to the increased invasive potential of bladder carcinoma cells.

91 ramatically increases the tumorigenicity and invasive potential of both normal and neoplastic mammary

92 ly, TBL1 knockdown significantly reduced the invasive potential of breast cancer cells by inhibiting

93 e that modulation of HP1(Hsalpha) alters the invasive potential of breast cancer cells through mechan

94 a membrane and play an important role in the invasive potential of breast-cancer cells.

95 that cotarget IGF-1R and HER2 may reduce the invasive potential of cancer cells that are resistant to

96 ubstrate activation, proliferation rate, and invasive potential of cancer cells, suggesting that furi

97 d gastric cancers, and may contribute to the invasive potential of cancer cells.

98 hich Vav1 can enhance the tumorigenicity and invasive potential of cancer cells.

99 nt of novel drugs selectively inhibiting the invasive potential of cancer cells.

100 on of the alpha6beta4 integrin increases the invasive potential of carcinoma cells by a mechanism tha

101 invasion assay, we found an increase in the invasive potential of CFPAC1 cells when they were cocult

102 promotes cell-cell adhesion and reduces the invasive potential of colon cancer cells.

103 esults suggest that PGE(2) might enhance the invasive potential of colorectal carcinoma cells via act

104 n process to compare the differentiative and invasive potential of cytotrophoblasts obtained from con

105 tion, perhaps limiting the proliferative and invasive potential of cytotrophoblasts within the uterus

106 sing the EP2 receptor, thereby enhancing the invasive potential of EP2-/- cells.

107 An increase in the invasive potential of ErbB2-overexpressing cells was obs

108 2 plays a role in suppressing the growth and invasive potential of human cancer cells, whereas others

109 emonstrate that the S100A4 gene controls the invasive potential of human CaP cells through regulation

110 ater than 90% loss of both the migratory and invasive potential of human lung adenocarcinoma cells.

111 inversely with Crk levels, motility and the invasive potential of human mammary carcinoma cells.

112 f furin causes a significant increase in the invasive potential of human tumor cells of low and moder

113 Re-expression of FoxM1 restored the invasive potential of IGF-1R knockdown cells treated wit

114 protease nexin-1 as causative for the highly invasive potential of LRC in melanomas.

115 Loss of AK4 expression suppressed the invasive potential of lung cancer cell lines, whereas AK

116 lizing antibody (Abs4A) reversed the subdued invasive potential of maspin transfectant cells in a dos

117 dvance the means of controlling the size and invasive potential of medfly populations.

118 deleted on chromosome 10 (PTEN), alters the invasive potential of melanoma cells in response to WNT/

119 n of Hif-1 activity is necessary to maintain invasive potential of migrating epithelial cells.

120 family kinase inhibitor, also decreased the invasive potential of N-cadherin transfectants and resul

121 ssociated with distinct phenotypes and hence invasive potential of N. meningitidis strains.

122 and local scales, as well as the outstanding invasive potential of Pelophylax aliens.

123 5 (S536E-NFkappaB-p65) significantly rescues invasive potential of PKCzeta-depleted breast cancer cel

124 acts as a signaling molecule that increases invasive potential of prostate cancer cells by NF-kappaB

125 Functional studies showed that the increased invasive potential of S100P-overexpressing cells was at

126 been shown to be a positive indicator of the invasive potential of some tumors.

127 pectively, varied linearly with the in vitro invasive potential of the 5 melanoma cell lines (A375P,

128 resence of flagella is required for the full invasive potential of the bacterium in tissue culture an

129 The invasive potential of the cell lines in vitro was measur

130 ) of HeyA8 cells significantly decreased the invasive potential of the cells and also increased docet

131 rage-independent growth, and suppressing the invasive potential of the cells in vitro.

132 functional MMP activity was measured by the invasive potential of the cells using a membrane invasio

133 Importantly, CYP1B1 depletion decreased the invasive potential of the endometrial cancer cells and e

134 The tumorigenicity and invasive potential of the luminal-like cancer cells reli

135 Also, SFRP1 depletion decreased the invasive potential of the metastatic RCC cell line, sugg

136 the cancer stem cell marker, CD44, leads to invasive potential of the tumor cells.

137 The invasive potential of the wild boar therefore probably l

138 Tivozanib decreased invasive potential of these cells, concomitant with redu

139 erved that FVIIa increased the migratory and invasive potential of these cells.

140 n-coated surfaces and increased the in vitro invasive potential of these cells.

141 as that may alter both the proliferative and invasive potential of these tumors.

142 e of Leptospira interrogans to elucidate the invasive potential of this spirochete.

143 ten silencing exacerbated the clonogenic and invasive potential of Tp53-deficient bone marrow-derived

144 letion of Rb in stromal fibroblasts enhances invasive potential of transformed epithelia.

145 t H1299 cells also significantly reduced the invasive potential of tumor cells by down-regulating exp

146 ession was associated with a decrease in the invasive potential of VCaP cells.

147 The invasive potential of wild boar in the Neotropics is pro

148 We explored the mechanism of VGSC-mediated invasive potential on the basis of reported links betwee

149 ongoing within-host evolution could increase invasive potential, possibilities that future studies sh

150 a (SCC), but the molecular events conferring invasive potential remain poorly defined.

151 The enhanced invasive potential required the presence of MMP-9 and at

152 xhibited both higher AREG levels and greater invasive potential than exosomes from isogenically match

153 tic make-up of a cancer cell may realize its invasive potential through a clonal evolution process dr

154 ays, c-src transfectants displayed a gain of invasive potential through Matrigel without an accompany

155 pare the abilities of strains with different invasive potentials to degrade this protein; and (iii) t

156 om 1.04 in the WM 35 melanoma cell line (low invasive potential) to 0.1 and 0.02 in the WM 983A and 1

157 Using cells of differing invasive potentials (uPAR-negative T-47D wild-type and u

158 Their invasive potential was also greatly reduced.

159 ollagenase, demonstrating that the decreased invasive potential was not due to a down-regulation of g

160 Because gelatinase B expression is linked to invasive potential, we studied the expression of gelatin

161 Na(+) channel activity and invasive potential were inhibited pharmacologically by t