ライフサイエンスコーパス: invention

1 g axis as a compelling realm for therapeutic invention.

2 uition to play a full role in the process of invention.

3 ity required a limited number of biochemical inventions.

4 rchin confirms a number of chordate specific inventions.

5 ems associated with patenting these sorts of inventions.

6 the issues that relate to patenting genomic inventions.

7 nt consequences for the supply and demand of inventions.

8 nsfer of their discoveries, innovations, and inventions.

9 ric light is one of the most important human inventions.

10 aryotic ancestor, with 40% likely eukaryotic inventions.

11 Since its invention 10 years ago, PMCA has helped to answer fundam

12 f diverse pathways suggests that these gene "inventions" along the lineage leading to animals were li

13 As in general, technological inventions also drive the development in the field of to

14 ict between hosts and viruses has led to the invention and diversification of molecular arsenals, whi

15 The invention and evolution of modern ophthalmic lasers have

16 Gero Miesenbock, and Georg Nagel 'for their invention and refinement of optogenetics'.

17 These changes reflected their invention and reinvention of the concept of a virus as i

18 ) hand anatomy, its associated grips and the invention and use of stone tools by early hominins.

19 he utility requirement for patenting protein inventions and consider the possible socioeconomic impac

20 essfully navigating the process of patenting inventions and licensing them to facilitate their use.

21 e minimum citation distance between patented inventions and prior scientific advances.

22 ration, physicochemical properties, patented inventions and recent advances of these micelles as effe

23 Innovation and invention are urgently needed to develop the in situ ins

24 d greater specialization and productivity at invention as individuals found it increasingly feasible

25 in amniote evolution and was not a mammalian invention as is usually supposed.

26 help to accelerate the rate of discovery and invention as well as improve higher education and the tr

27 he indirect pathway is a recent evolutionary invention, as might be implied from its localization to

28 avy-particle radiation therapy, is not a new invention, but it has gained considerable public attenti

29 ey are either a demonstration of independent invention by Neandertals or an indication that modern hu

30 ht about a change in the way that biological inventions can be protected by patent laws.

31 eview we describe a holistic approach to the invention, development and optimisation of biotransforma

32 hropogenic values by midcentury will require invention, development, and deployment of schemes for ca

33 cifying the identity of ovules, the landmark invention during the course of vascular plant evolution

34 ineers who had the tenacity to develop their inventions, followed by a series of technical innovation

35 sing incentives to differentiate the task of invention from that of commercializing new technologies

36 and increased in switching speed since their invention in 1947.

37 ngs identified a novel point for therapeutic invention in NSCLC that may be tractable to small-molecu

38 ss builds upon itself, with the expansion of invention in one domain propelling future work in linked

39 Since their invention in the 1950s, composite carbon electrodes have

40 Since its invention in the early 1990s, differential display (DD)

41 he most poisonous and sophisticated cellular inventions in animal evolution.

42 To what extent will KSR limit combination inventions in biotech?

43 npatentable natural phenomena and patentable inventions is crucial in preventing the patent laws from

44 hich scientific advances support marketplace inventions is largely unknown.

45 This Zeiss invention lacked only the slit illumination of today's i

46 Review, we highlight recent developments and inventions made by introducing the fourth dimension of t

47 and physical capital required for effective invention, making it increasingly desirable for individu

48 Information relating to the source invention may be incomplete, and biological information

49 e field and review contributions to reaction invention, mechanism, and application to complex molecul

50 A key component of this work is the invention of "borono-sclareolide", a terpenyl radical pr

51 Pioneered with the invention of (11)C-Pittsburgh compound B, amyloid-beta i

52 In this article, the invention of a directing group to achieve such a transfo

53 orts to address these issues have led to the invention of a large number of protecting groups that te

54 The invention of a method for the synthesis of 1,3-diols fro

55 This required invention of a method to correct for the cell artifact a

56 This report details the invention of a method to enable syntheses of psychotrimi

57 Herein we report the invention of a new guanidine-based chlorinating reagent,

58 Herein, we report the invention of a new reagent (Zn(SO(2)CF(2)H)(2), DFMS) fo

59 amatic changes in function - essentially the invention of a new regulatory protein.

60 hese unique responsive dynamics motivate the invention of a series of optical devices triggered by mo

61 arise at all stages of innovation, from the invention of a technology through its selection, product

62 The invention of a WUS-like function within the WOX gene fam

63 pulation growth through time reveal that the invention of agriculture facilitated a fivefold increase

64 The invention of agriculture is widely assumed to have drive

65 Frequent re-invention of analogous architectures involving functiona

66 The Mangarevan invention of binary steps, centuries before their formal

67 Since the invention of biosensor, many ideas and methods have been

68 ses that the genetic code coevolved with the invention of biosynthetic pathways for new amino acids.

69 Since the invention of cancer radiotherapy, its primary goal has b

70 Similarly, the invention of cooking possibly affected the evolution of

71 omes to autosomes, which has resulted in the invention of diverse mechanisms to equilibrate gene expr

72 The invention of DNA cloning over 40 years ago marked the ad

73 As the invention of DNA sequencing in the 70s, computational bi

74 This sub-discipline was galvanized by the invention of DNA shuffling, a procedure that randomly re

75 imarily from Arabidopsis has also led to the invention of effective gene knock-down technologies that

76 olar-to-fuel energy conversion relies on the invention of efficient catalysts enabling water oxidatio

77 Following the invention of electron optics during the 1930s, lens aber

78 Although the invention of enantioselective variants is an ongoing cha

79 the optimization of existing enzymes and the invention of entirely new biocatalytic reactions that we

80 y demonstrated herein sets the stage for the invention of further multicomponent reactions in future.

81 e brought about by innovations that spur the invention of further, related, technology, and which occ

82 of the process of transformation and to the invention of innovative preventive and therapeutic cance

83 ered" via a cultural stimulus, plausibly the invention of language.

84 Since the invention of laser scanning confocal microscopy in the 1

85 The invention of metal-organic frameworks and zeolitic imida

86 -341 (bortezomib) in solid tumors led to the invention of MLN9708 (ixazomib), an orally bioavailable

87 n goal of applying them to the discovery and invention of new and better medicines, especially in are

88 Cultural change occurs chiefly through invention of new behavioral variants combined with socia

89 ch in this field has largely focussed on the invention of new catalysts and the optimization of their

90 llenge to achieving this overall goal is the invention of new catalysts for the reductive and oxidati

91 between common families, as compared to the invention of new families and recombination among these,

92 e phase of terpene biosynthesis inspires the invention of new methodologies, since working with carbo

93 posed synthetic challenges that required the invention of new methodology.

94 rs derived from Amerindian languages and the invention of new names for neotropical plants from Afric

95 ation of conserved enhancers rather than the invention of new ones.

96 uplication of existing genes rather than the invention of new ones.

97 The invention of new strategies for the design of protein-mi

98 These findings, together with the invention of new tools to study persisters, could have i

99 onic properties to a metal, will support the invention of new transformations not previously possible

100 The invention of next-generation sequencing technology has m

101 and materials sciences have resulted in the invention of numerous hybrid molecules that possess stre

102 The invention of oxygenic photosynthesis by cyanobacteria 2.

103 The invention of paper as writing materials has greatly cont

104 Prior to the invention of pars plana vitrectomy, such surgery was inn

105 ge-specific proteins rather than large-scale invention of protein-coding capacity.

106 Since the invention of quantum mechanics, even the simplest exampl

107 The invention of signals decreasing uncertainty about relati

108 The invention of single molecule localization microscopy (SM

109 The recent invention of super-resolution fluorescence microscopy br

110 The recent invention of superresolution microscopy has brought up m

111 Here, we suggest that the invention of synthetic ligand--GPCR pairs (aka DREADDs,

112 ounds was added to the main subjects and the invention of the atomic force microscope provided new wa

113 ral conditions were developed long after the invention of the electric devices suspected of delaying

114 The invention of the esophagoscope confirmed that GERD was a

115 These data also strengthen the argument for invention of the genetic code in an RNA world and for th

116 The invention of the Kalman filter is a crowning achievement

117 has been the desire of scientists since the invention of the laser 40 years ago.

118 The invention of the laser has resulted in many innovations,

119 Since the invention of the laser more than 50 years ago, scientist

120 ork of multiple investigators leading to the invention of the laser, its biophysical effects on ocula

121 he foot colliding with the ground before the invention of the modern shoe.

122 targeted the phonon laser (saser) since the invention of the optical laser over 50 years ago.

123 The invention of the placenta facilitated the evolution of m

124 The invention of the scanning tunnelling microscope revoluti

125 The invention of thermally resistant ceramic cooking vessels

126 that prehistoric transaction records and the invention of writing for recordkeeping were linked to in

127 rmation of the human diet resulting from the inventions of agriculture and animal husbandry.

128 that followed for thousands years until the inventions of agriculture?

129 esis posits that DNA and proteins were later inventions of early life, or the chemistry that gave ris

130 The issue of patents on inventions of genomic research is the subject of intense

131 Reading, one of the most important cultural inventions of human society, critically depends on poste

132 in himself and others, civic activities, and inventions of medical devices.

133 he Haber Bosch process is among the greatest inventions of the 20th century.

134 evolve cell designs is a product of communal invention, of the universal HGT field, not intralineage

135 Like the two sides of a coin, any new invention or discovery also possess their two faces.

136 The role of creativity in the discovery and invention processes is also discussed.

137 Biotechnology inventions raise both moral and technical dilemmas.

138 proceeded largely by gene duplication and/or invention rather than by modification of extant proteins

139 Since its invention, SAGE has been widely applied to analyzing gen

140 s an ancient and highly conserved eukaryotic invention, self-incompatibility systems such as mating t

141 mental illness, some group-level anti-stigma inventions show promise and merit further assessment; (3

142 ver, notwithstanding eukaryote-specific gene inventions, single-gene phylogenies have never traced eu

143 rs mediating tumor outgrowth and therapeutic invention strategies against lymphoma.

144 The patent system was developed to protect inventions such as the Spinning Jenny and Stevenson's Ro

145 and some of them presaged later dinosaurian inventions, such as thickened skull roofs.

146 ST, freely accessible over the web at http://invention.swmed.edu.

147 ion database, are freely available at http://invention.swmed.edu/ and http://spore.swmed.edu/dejavu

148 ly accessible through the Internet at http://invention.swmed.edu/etblast/etblast.shtml, where users c

149 ith implications for the definition of novel invention targets (e.g., activin A and CD36) to prevent

150 paradoxical, given that reading is a recent invention that could not have influenced the genetic evo

151 g patent applications directed to biological inventions that are claimed in more conventional terms.

152 served non-coding elements (CNEs) are recent inventions that postdate the divergence of Eutheria and

153 In the 25-year period since its invention, the STM has helped uncover a wealth of phenom

154 databases continue to yield new insights and inventions, the commercial incentive to conflate race an

155 vings now underway can be traced to a single invention--the blue light-emitting diode.

156 f the human brain and represents evolution's invention to enable the nervous system to escape the res

157 and animal kingdoms, DRP5B is a plant/algal invention to facilitate the division of their organelles

158 ecognized by the 2007 ACS Award for Creative Invention, we discuss the discovery of a new synthetic r

159 evement of a high level of specialization at invention well before the rise of large-scale research l

160 ocation and duration of disease, and medical inventions were analyzed.

161 now seek to protect certain aspects of their inventions, which include software, methods of doing bus

162 multiple times due to the filing of the same invention with multiple patent offices, or the use of th

163 Since their invention, XTEN polypeptides have been utilized to exten