ライフサイエンスコーパス: inverted terminal repeat

1 ins that form the capsid, and the right-hand inverted terminal repeat.

2 d polymerase to specific sequences in the Ad inverted terminal repeat.

3 ouble-stranded DNA (dsDNA) genome with large inverted terminal repeats.

4 he starting element, i.e., at the end of the inverted terminal repeats.

5 replication centers and recognize the viral inverted terminal repeats.

6 ial genes in a central region and in 6.5-kbp inverted terminal repeats.

7 A molecule of 16,687 nucleotides with 143-bp inverted terminal repeats.

8 thin the hairpin structure formed by the AAV inverted terminal repeats.

9 ette flanked by adeno-associated virus (AAV) inverted terminal repeats.

10 e is flanked by adeno-associated virus (AAV) inverted terminal repeats (Ad.LCR-beta-GFP).

11 g adenovirus sequences adjacent to the right inverted terminal repeat and by incorporated a number of

12 rates: the Rep binding site within the viral inverted terminal repeat and one of the terminal hairpin

13 er form, and vectors were created with AAV-2 inverted terminal repeats and AAV-1 Rep and Cap function

14 us (CMV)-TNFR:Fc vector (containing the AAV2 inverted terminal repeats and AAV5 capsid) to the rat lu

15 l coding region bounded by identical 3.7-kbp inverted terminal repeats and contains 150 putative gene

16 l coding region bounded by identical 2.4 kbp-inverted terminal repeats and contains 156 putative gene

17 l coding region bounded by identical 9.5-kbp inverted terminal repeats and contains 260 open reading

18 of a central coding region bounded by 7-kbp inverted terminal repeats and contains 267 open reading

19 The 212-kbp genome contained 7.5-kbp inverted terminal repeats and lacked extensive terminal

20 rus containing the Ad7 genome except for the inverted terminal repeats and packaging sequence from Ad

21 ition sequence (RRS) found in both the viral inverted terminal repeats and the AAVS1 integration locu

22 in vivo approach to address the role of the inverted terminal repeats and the covalently linked term

23 on their structures and the sequences of the inverted terminal repeats and the putative transposase p

24 report we identify a single AD domain of the inverted terminal repeat as a minimal origin of cAAV rep

25 to the rest of the genes, forming a part of inverted terminal repeat characteristic of linear mtDNA

26 The existence of double-D inverted terminal repeat circular intermediates in SCID

27 d sequence features with the exception of an inverted-terminal-repeat consensus sequence that has sim

28 Sequence analysis reveals that the 145 bp inverted terminal repeats contain the 5'-TGellipsisCA-3'

29 tegration into chromosome 19 when present in inverted terminal repeat-containing recombinant AAV (rAA

30 and-specific endonuclease cut within the AAV inverted terminal repeat DNA.

31 Candida salmanticensis, is characterized by inverted terminal repeats each consisting of several tan

32 e placed between late region 5 and the right inverted terminal repeat, efficiently expressed fiber an

33 y the p5IEE occurs in the absence of the AAV inverted terminal-repeat elements.

34 nce element which functions in cis to an AAV inverted terminal repeat-flanked target gene.

35 A-mediated transposable elements with short, inverted terminal repeats, have been reported in a wide

36 m interacts with the D-sequence in the viral inverted terminal repeat, inhibits viral second strand D

37 he single-stranded D sequence within the AAV inverted terminal repeats, inhibits viral second-strand

38 palindrome (BB'), necessary for optimal Rep-inverted terminal repeat interaction, does not contribut

39 duction over phage and that incorporation of inverted terminal repeats is associated with improved fa

40 To characterize the role of the AAV inverted terminal repeat (ITR) cis-acting sequences in t

41 , we show that DNA-PKcs and Artemis open AAV inverted terminal repeat (ITR) hairpin loops in a tissue

42 protein to the rep-binding site (RBS) of AAV inverted terminal repeat (ITR) in males compared with fe

43 ind the hairpin structures formed by the AAV inverted terminal repeat (ITR) origins of replication, m

44 V nonstructural proteins (Rep) in trans, and inverted terminal repeat (ITR) sequences in cis.

45 e sought to evaluate the mechanisms by which inverted terminal repeat (ITR) sequences mediate intermo

46 majority of AAV2 breakpoints were within the inverted terminal repeat (ITR) sequences, which contain

47 vealed the ubiquitous presence of a double-D inverted terminal repeat (ITR) structure, which implied

48 ation is dependent on two copies of a 145-bp inverted terminal repeat (ITR) that flank the AAV genome

49 ranscription initiation site within the AAV5 inverted terminal repeat (ITR), and mapping of the AAV5

50 Within the inverted terminal repeat (ITR), several base changes wer

51 tein (GFP) transgene cassette flanked by AAV inverted terminal repeats (ITRs) (Ad.AAV-LCR-GFP), trans

52 They bind specifically to the AAV inverted terminal repeats (ITRs) and possess ATPase, hel

53 concatemers with occasional deletions of the inverted terminal repeats (ITRs) and their flanking sequ

54 The inverted terminal repeats (ITRs) are also unique compare

55 AV7 and AAV8 were generated by using rep and inverted terminal repeats (ITRs) from AAV2 and were comp

56 left-hand open reading frame (ORF) and both inverted terminal repeats (ITRs) have the highest homolo

57 ncluded a DNA element encompassing two viral inverted terminal repeats (ITRs) in a head-to-tail orien

58 termed the D sequence, from both ends of the inverted terminal repeats (ITRs) in the adeno-associated

59 s derived from recombination between (i) AAV inverted terminal repeats (ITRs) in the recombinant plas

60 ssociated virus type 2 (AAV) genome contains inverted terminal repeats (ITRs) of 145 nucleotides.

61 primers designed to match the right and left inverted terminal repeats (ITRs) of the transposon.

62 These inverted terminal repeats (ITRs) play an important role

63 1287 base pairs (bp) long, has 30 bp perfect inverted terminal repeats (ITRs), and encodes a 343 amin

64 Rep recognition sequences (RRSs) in the AAV inverted terminal repeats (ITRs), the AAV p5 promoter, a

65 E3, and late genes, but containing the viral inverted terminal repeats (ITRs), transgene expression c

66 ing of the proviral genome played by the AAV inverted terminal repeats (ITRs), which consist of a pal

67 was flanked by adeno-associated virus (AAV) inverted terminal repeats (ITRs).

68 ated by adeno-associated virus (AAV) Rep and inverted terminal repeats (ITRs).

69 ration locus, the viral p5 promoter, and the inverted terminal repeats (ITRs).

70 ion of the AAV genome: Rep78/68 proteins and inverted terminal repeats (ITRs).

71 of the junction sequences involving the AAV inverted terminal repeats (ITRs).

72 nced by using viral DNA packaging sequences (inverted terminal repeats [ITRs]) derived from AAV genot

73 By contrast, miniature inverted terminal repeats (MITEs) occur at a similar fre

74 taining the target sequence derived from the inverted terminal repeat; nontarget DNA stimulates ATPas

75 the integration of a plasmid containing AAV inverted terminal repeats occurred at high frequency, su

76 is evidence of genome recombination, as the inverted terminal repeat of HAdV-4vac is initially ident

77 Additionally, mutation of the inverted terminal repeat of the rAAV genome, which has b

78 with one breakpoint precisely located at an inverted terminal repeat of the retained starting elemen

79 The AAAV genome has inverted terminal repeats of 142 nucleotides, with the f

80 heterologous DNA sequences cloned within the inverted terminal repeats of AAV and subsequently packag

81 he sequences of regulatory protein (rep) and inverted terminal repeats of AAV into an HSV amplicon ve

82 ella virus PBCV-1, the SC-1A genome contains inverted terminal repeats, one of which is adjacent to t

83 placement of the p5 RBE with either the AAV2 inverted terminal repeat or the AAVS1 RBE sequence eleme

84 quences derived from PER.C6 cells flanked by inverted terminal repeat, packaging signal, and transgen

85 The AAV inverted terminal repeats, present in cis, were not esse

86 EAMs contain only the inverted terminal repeats required for replication and f

87 lasmid in a way that is dependent on the AAV inverted terminal repeat sequence.

88 n which CFTR gene was expressed from the AAV inverted terminal repeat sequence.

89 , first-generation Ad vectors containing AAV inverted terminal repeat sequences (ITRs) flanking a rep

90 anking expression cassettes of interest with inverted terminal repeat sequences (ITRs) from adeno-ass

91 is approximately 3.1 kb in length with 19-bp inverted terminal repeat sequences having a single misma

92 showed that Himar1 transposase binds to the inverted terminal repeat sequences of its cognate transp

93 that was further increased by including the inverted terminal repeat sequences of the adeno-associat

94 r of AAV5, within viral constructs that lack inverted terminal repeat sequences, displays a high basa

95 eletions and extensive rearrangements in the inverted terminal repeat sequences.

96 duplicated IRs, Ad packaging signals, and Ad inverted terminal repeat sequences.

97 th the single-stranded D sequence within the inverted terminal repeat structure of the AAV genome and

98 ind to imperfect palindromic elements in the inverted terminal repeat structures at the 3'- and 5'-en

99 ains a small single-stranded DNA genome with inverted terminal repeats that form hairpin structures.

100 The piggyBac (IFP2) short inverted terminal repeat transposable element from the c

101 and crystallography have deciphered several inverted terminal repeat-transposase complexes that are

102 g on itself and replication back through the inverted terminal repeat, using itself as a template.

103 A pair of inverted terminal repeats was detected in YSLPV1, sugges

104 omain, and specific DNA sequences containing inverted terminal repeats with similarity to piggyBac tr