ライフサイエンスコーパス: inviable

1 tion, because a Deltaisu1Deltaisu2 strain is inviable.

2 or growth, but mga2 spt23 double mutants are inviable.

3 hich either of these motifs is disrupted are inviable.

4 e interaction of the J domain with Hsp70 are inviable.

5 combinations of spt3 and mot1 mutations are inviable.

6 sporulate poorly and the spores produced are inviable.

7 of the XY sex are preferentially sterile or inviable.

8 olynucleotide phosphorylase were found to be inviable.

9 n cell growth, spt23 mga2 double mutants are inviable.

10 and that spt3 delta toa1 double mutants are inviable.

11 n2 cln3 triple mutant is Start defective and inviable.

12 yeast cells lacking both Bem2p and Dbm1p are inviable.

13 e fraction that are either female sterile or inviable.

14 use pfy1-111, but not wild-type, cells to be inviable.

15 is essential as trf4 trf5 double mutants are inviable.

16 Tyr residues mutated to Phe (Rpb1-Y1F) were inviable.

17 placing the wild-type gene, the cells became inviable.

18 s in yeast, and spa2delta cdc10-10 cells are inviable.

19 s of selfing, but selfed progeny were mostly inviable.

20 F(1), and almost all hybrid self-progeny are inviable.

21 the progeny of these divisions are typically inviable.

22 lpha1 and alpha2 together rendered the cells inviable.

23 le but sterile: the gametes they produce are inviable.

24 etions, cln3 delta ccr4 delta cells are also inviable.

25 ng the killer element fail to mature and are inviable.

26 s carrying null mutations of either gene are inviable.

27 in "crisis," a period when most cells become inviable.

28 knockout mutations in them are by definition inviable.

29 tants lacking both atToc120 and atToc132 are inviable.

30 phorylase (PNPase) and RNase R activities is inviable.

31 ants are viable whereas the double mutant is inviable.

32 s and fertility, but the double mutants were inviable.

33 Null mutants of each are inviable.

34 mutants gradually died, and the plants were inviable.

35 ell because a strain lacking both kinases is inviable.

36 ts combining mutations in two RFC genes were inviable.

37 in region II in Pol delta or Pol epsilon are inviable.

38 nd pcl1 Delta pcl2 Delta cdc42-1 strains are inviable.

39 ve, temperature-sensitive, and anaerobically inviable.

40 We found that rpaA-null mutants are inviable after several hours in the dark and compared th

41 elta dnf2Delta dnf3Delta quadruple mutant is inviable, although any one member of this group can main

42 ding these hydrolytic enzymes are considered inviable, although their exact nature has not been studi

43 Strains lacking both NCS1 and NOH1 were inviable and arrested as unbudded cells, implying that P

44 Clb2p-depleted cells were inviable and arrested with hyper-elongated projections c

45 g individual mcd1 or smc3 mutant alleles are inviable and defective for both sister chromatid cohesio

46 ppc89Delta cells are inviable and exhibit defects in SPB integrity, and hence

47 over, cells lacking Clb5, Clb6, and Pds1 are inviable and lose cohesion during an unperturbed S phase

48 ada3 swi1, and gcn5 swi1 double mutants are inviable and that mutations in SIN1 allow viability of t

49 GTP or that bind but cannot hydrolyze it are inviable and unable to support nuclear transport of RNAP

50 nations of FG-nups from the pore to simulate inviable and viable NPCs that were previously studied ex

51 helicase and the Mus81/Mms4 endonuclease are inviable, and indirect studies implicate homologous reco

52 metophytes lacking both DRP2A and DRP2B were inviable, arresting prior to the first mitotic division

53 Mutants of dnaAcos are inviable at 30 degrees C because DnaAcos hyperinitiates,

54 pe A and serotype D calcineurin mutants were inviable at 37 degrees C and avirulent in mice, whereas

55 We found that Deltaelm1 Deltaswe1 cells are inviable at 37 degrees C and that a large proportion of

56 The null mutant is inviable at 37 degrees C, demonstrating that the OST4 ge

57 were alive but misshapen at 30 degrees C and inviable at 37 degrees C.

58 Cells from which BEM4 was deleted were inviable at 37 degrees C.

59 ells, but it rendered the nup116 null strain inviable at all temperatures and coincidentally resulted

60 ls accumulate toxic 4-carboxysterols and are inviable at high temperature.

61 Homozygous cdc28-4(ts) clb5 diploids were inviable at room temperature.

62 ine; consequently, many meiotic products are inviable because of aneuploidy.

63 Hybrids between species are often sterile or inviable because the long-diverged genomes of their pare

64 sbp1(-) yeast were inviable but could be rescued by all four exogenous prot

65 Delta cln1 Delta cln2 Delta strains are also inviable, but are rescued by osmotic stabilization with

66 An oxidase-deficient Mia40 mutant is inviable, but can be partially rescued by the addition o

67 imals defective in both sag-1 and eat-16 are inviable, but reducing function in egl-30 restores viabi

68 ession of eIF2 subunits rescued an otherwise inviable cdc123 deletion mutant.

69 e-induced genes, and a morphologically mixed inviable cell fate.

70 uction box resulted in rapid accumulation of inviable cells, frequently multiply budded, with DNA con

71 nondisjunctional progeny, to account for the inviable classes.

72 bition is likely due to the formation of an "inviable complex" which becomes degraded, rather than by

73 and mutants lacking both Elo2p and Elo3p are inviable confirming that the very long-chain fatty acids

74 ble mutant in calcineurin (CNB1) and FKS1 is inviable due to a deficiency in FKS2 expression.

75 apn1 apn2 rad1 yeast are inviable due to accumulation of abasic sites and strand

76 Embryos from mex-5 single-mutant mothers are inviable due to the misexpression of SKN-1, a transcript

77 All of the transgenic lines were homozygote inviable, dying neonatally and exhibiting heart malforma

78 However, they produce inviable embryos that succumb to failure of mitosis caus

79 cking Heterochromatin Protein 1E (HP1E) sire inviable embryos that undergo catastrophic mitosis.

80 , by observing uric acid deposits in unfixed inviable embryos, we identified five previously describe

81 propriately processed, leading to permeable, inviable embryos.

82 ssion of UvsW allows growth of an (otherwise inviable) Escherichia coli recG rnhA double mutant, cons

83 Whereas vti1Delta cells are inviable, expression of hVti1 allows vti1Delta cells to

84 umption that genotype fitness can only be 0 (inviable genotype) or 1 (viable genotype).

85 escued by mutations known to rescue normally inviable hybrid males.

86 Drosophila melanogaster mutation Hmr rescues inviable hybrid sons from the cross of D. melanogaster f

87 educing Hmr(+) activity can rescue otherwise inviable hybrids.

88 nsiently hypermutable fraction that would be inviable if cells were haploids.

89 Cells depleted of Pfh1 were inviable if they also lacked the human TIMELESS homolog

90 (R275Q, E295K, and A302D) caused cells to be inviable in an in vivo assay in which the mutant beta' i

91 dentified in a screen for mutations that are inviable in combination with a top1 null mutation.

92 constant light conditions, but renders cells inviable in cycling conditions when light and dark perio

93 UBR2-/- mice are inviable in some strain backgrounds and are defective in

94 vation that if only one gender is sterile or inviable in species hybrids, it is nearly always the het

95 s of wild-type morphology, but the mutant is inviable in the absence of fixed nitrogen and unable to

96 d to as "petite-positive" and those that are inviable in the absence of mitochondrial DNA are termed

97 mperature-sensitive growth phenotype and are inviable in the absence of mitochondrial DNA.

98 ing, we screened for yeast mutants that were inviable in the absence of sterol esterification.

99 ed and polysumoylated proteins, and they are inviable in the absence of the Sgs1 DNA helicase.

100 Many pollen grains were collapsed and inviable in the gsl1-1/gsl1-1 gsl5/+ and gsl1-1/+ gsl5/g

101 Haploid cells lacking cdc24(+) are inviable, indicating that cdc24(+) is an essential gene.

102 dna2-1 rad27/rth1 delta double mutants are inviable, indicating that the mutations are syntheticall

103 riately progress through meiosis, generating inviable meiotic products.

104 de the pore does not exceed 185 mg/mL in the inviable NPCs, whereas for the wild-type and viable NPCs

105 An inp51 inp52 inp53 triple mutant is inviable on standard medium, but can grow weakly on medi

106 ell aneuploidy and subsequent development of inviable or abnormal progeny.

107 ne chromosome, is deleterious and results in inviable or defective progeny if passed through the germ

108 s": those alleles whose interaction produces inviable or infertile interspecific hybrids but does not

109 ses the production of diploid males that are inviable or infertile, imposing a high cost on matings b

110 arp7 delta and arp9 delta mutants are either inviable or show greatly impaired growth and Swi-/Snf- m

111 Diploid males, which are inviable or sterile in almost all cases studied, are the

112 The rate of male-specific inviable or sterile mutations is 5 x 10(-4)/generation,

113 the heterogametic sex are more likely to be inviable or sterile than the homogametic sex because som

114 Diploid males are developmentally inviable or sterile, and the likelihood of diploid male

115 the rate at which homogametic hybrids become inviable or sterile.

116 nd represent a genetic load because they are inviable or sterile.

117 males are genetic dead ends because they are inviable or sterile.

118 ocus become diploid males, which are usually inviable or sterile.

119 of the paternal genome that renders embryos inviable or unable to complete diploid development in cr

120 These microbial partners are inviable outside of specialized host tissues, and theref

121 ot package any DNA, (4) four mutants, though inviable, package the entire lambda chromosome, and (5)

122 Expression of human PDK1 in otherwise inviable pkh1Delta pkh2Delta cells permitted growth.

123 h convert a basal proliferative cell into an inviable rigid squame.

124 ngation-defective and termination-proficient inviable rpoB alleles that affect highly conserved resid

125 ploid A. lyrata and A. arenosa causes mainly inviable seed formation, revealing a strong postzygotic

126 4 plants have diminished stature and produce inviable seeds.

127 ng diploid males, which are often sterile or inviable, sl-CSD can generate substantial inbreeding dep

128 her a red nor a hop1 mutation can rescue the inviable spores produced by a rad52 spo13 strain; this p

129 Finally, mum4-1 mutants produce inviable spores.

130 nes, fail to secrete AcbA and, thus, produce inviable spores.

131 eferentially forms viable spores rather than inviable stalk cells.

132 t the ybr159Deltaayr1Delta double mutant was inviable, suggesting that Ayr1p is responsible for the r

133 the ER-mitochondria encounter structure) are inviable, suggesting that the EMC also functions as a te

134 Deltapch1 cells are inviable, therefore S. pombe has two essential genes tha

135 Inviable TRA1 mutants all showed defects in SAGA and NuA

136 elicases with Deltarep DeltauvrD cells being inviable under rapid growth conditions.

137 with an inactive endogenous vma-1 gene were inviable unless a functional copy of the gene cosegregat

138 Cells are inviable upon BRCA2 loss, which leads to replication str

139 to methylmethane sulfonate, and they become inviable upon introducing either the sgs1Delta or rad54D

140 vertebrates, and mouse Nbs1-null mutants are inviable, we tested the hypothesis that the NBS1 657del5

141 haploid and heterozygous tub1-724 cells are inviable when another microtubule effector, PAC2, is ove

142 m30) allele become sterile and their progeny inviable when fed Q7-containing bacteria.

143 f Saccharomyces cerevisiae mutants that were inviable when present in a rad52 null mutation backgroun

144 s involved in morphogenesis are specifically inviable when the Pho85-associated G1 cyclins encoded by

145 Double mutants of dpl1 and ysr2 were inviable, whereas dpl1 ysr2 lcb4 triple mutants were via

146 rdgB recBC cells are inviable, whereas rdgB recF cells are healthy, suggestin

147 ila simulans are mated, the male progeny are inviable, whereas the female progeny display manifold ma

148 of endosperm development and are completely inviable, while others develop relatively normally at fi

149 re isolated in a screen for mutants that are inviable with deletions in the G1 cyclins CLN1 and CLN2.

150 le in the presence of full-length Ent1p, but inviable with only Ent1DeltaCBMp; these strains were nam

151 eins are genetically redundant, as cells are inviable without at least one of the two BDF genes.

152 Cells lacking all three nucleases are inviable without RecG.

153 value of males, caused by the production of inviable Y0 embryos in X0 x X'Y matings, can outweigh an

154 Otherwise inviable ypk1Delta ykr2Delta cells were fully rescued by