ライフサイエンスコーパス: involute

1 se in size and number and then progressively involute.

2 components of the immune response appear to involute.

3 arization in group A, and neovascular fronds involuted after treatment with CAI in group B.

4 n the simultaneous presence of secretory and involuting alveoli as well as resting ductules.

5 During gastrulation, organizer cells involute and form the prechordal plate anteriorly and th

6 ate postprocedure MR images that, over time, involutes and is associated with decreasing signal inten

7 trulation proceeds, the iro3 positive domain involutes and migrates to the animal pole.

8 ver granulomas developed at weeks 2 to 4 and involuted, and (iii) leishmanicidal responses to antimon

9 rate that cells fated to form myotome do not involute around the recurved epithelium of the DML but r

10 ic vesicle elongation and retinal precursors involute around the rim of the invaginating optic cup.

11 following a range of toxic insults, and also involutes as part of the aging process, albeit at a fast

12 tocranial bone layers at P7 which eventually involutes at P13.

13 samples with control coils showed primarily involuting blood elements with minimal fibroblast prolif

14 n the ability to attach to this region, only involuting cells arising from the dorsal and ventral lip

15 artially regresses and stabilizes (i.e., non-involuting congenital hemangioma [NICH]).

16 umor either involutes quickly (i.e., rapidly involuting congenital hemangioma [RICH]) or partially re

17 We report 2 cases of ulcerated rapidly involuting congenital hemangiomas (RICH) that were compl

18 7), late pregnancy (e20), lactating (day 4), involuting day 1, and involuting day 11.

19 0), lactating (day 4), involuting day 1, and involuting day 11.

20 tbx6 is expressed transiently in the involuting derivatives of the ventral mesendoderm, which

21 Cell division is also absent in involuting dorsal mesoderm during gastrulation in Xenopu

22 rst 2 weeks, renal RF thermal ablation zones involuted during the remainder of the MR imaging follow-

23 , T is also expressed during gastrulation in involuting endodermal and mesodermal cells, and in verte

24 s also activated in the hyperplastic but not involuted follicles of HIV-associated lymphadenopathy in

25 nds of transgenic females invariably fail to involute fully after lactation.

26 were depleted (to 34%-61% of vehicle), with involuted germinal centers apparent in the spleen.

27 e age-matched virgin gland in the completely involuted gland.

28 d whether the tissue microenvironment of the involuting gland is also promotional.

29 cancer patients, are recruited to the normal involuting gland.

30 her numbers of apoptotic cells were found in involuting glands at 48 h compared to control glands.

31 teinase activity in the matrix isolated from involuting glands.

32 antly in proliferating but not involuting or involuted hemangioma.

33 Cultured proliferating and involuting hemangioma endothelial cells were treated wit

34 ifferentially expressed in proliferating and involuting hemangiomas in vivo will contribute to our un

35 profiling of vessels from proliferating and involuting hemangiomas to identify differentially expres

36 Involuting hemangiomas were characterized by the express

37 al EndMT transcription factors Snail/Slug in involuting hemangiomas.

38 These goblet cells were markedly involuted however, most notably in the villi.

39 sent at embryonic day 3.5, these blastocysts involute in culture as a result of massive apoptosis.

40 derm and for rare cells of the gastrula that involute into the hypoblast, motility appears wild-type.

41 We present genetic evidence that an involuted mammary gland is fundamentally different from

42 aintenance of this epithelial subtype in the involuted mammary gland.

43 Here we report that the involuted mammary glands from transgenic mice overexpres

44 Overexpression of int-5/aromatase in involuted mammary glands of transgenic females induces h

45 However, multiparous mice, in which the involuting mammary epithelial cells have been repeatedly

46 1B is not expressed in virgin, lactating, or involuting mammary epithelium.

47 gland development showed high levels in the involuting mammary gland and in preneoplastic hyperplasi

48 Immunoprecipitations from cell culture and involuting mammary gland demonstrated that this truncati

49 ilysin expression increased apoptosis in the involuting mammary gland of mice that had undergone a si

50 volved in cell survival in the lactating and involuting mammary gland, but that overexpression of AKT

51 oreover, mCLCA5 was induced in lactating and involuting mammary gland, correlating with differentiati

52 In the involuting mammary gland, inhibition of COX-2 reduces th

53 replenishment, and stromal remodeling in the involuting mammary gland, producing a phenotype resembli

54 physiological activator of STAT3, because in involuting mammary glands of Lif(-/-) mice, pSTAT3 is ab

55 thermore, breast cancer cells exposed to the involuting mammary microenvironment acquired prolymphang

56 el, human breast cancer cells exposed to the involuting mammary microenvironment form large tumors th

57 required for the attachment and migration of involuting marginal zone (IMZ) cells were analyzed in vi

58 ling between all the inducing tissues of the involuting marginal zone and the responding prospective

59 us has "surface mesoderm" originating in the involuting marginal zone epithelium.

60 t stage 10-, a massive rotation of the lower involuting marginal zone occurs around an internal lip.

61 ior to dorsal lip formation and in the early involuting marginal zone.

62 ecording explants of deep neural tissue with involuted mesoderm attached and of deep neural tissue al

63 Dorsal-involuted mesoderm is a major source of secreted BMP ant

64 uction occurs in zebrafish in the absence of involuted mesoderm, indicating that this tissue and sign

65 which the degree of contact with underlying, involuted mesoderm-endodermal tissues was marked, and "o

66 stent vertical interactions with underlying, involuted mesoderm.

67 otemporally regulated and is detected in the involuting mesoderm during gastrulation.

68 These defects arise because the involuting mesoderm fails to move appropriately.

69 ad and migrate on FN whereas presumptive pre-involuting mesoderm, vegetal pole endoderm, and animal c

70 hat are devoid of mitotic cells, such as the involuting mesoderm.

71 ons of the blebby transitional morphology of involuting mesodermal cells in a vertebrate embryo.

72 and stroma-rich tumors were less frequent in involuted mice or in age-matched nulliparous mice.

73 epithelial cell proliferation, in virgin or involuting mice.

74 growth-arrested HC11 cell extracts and 24 h involuting mouse mammary gland extracts.

75 In the involuting mouse prostate, FasL and matrilysin colocaliz

76 c role for the transcription factor STAT3 in involuting murine mammary epithelium, resulting in delay

77 a previously suggested hypothesis regarding involuting nevi in BRAF inhibitor therapy is correct: Ne

78 Biopsy findings from 1 unchanged and 1 involuted nevus showed BRAF wild type in the unchanged n

79 e unchanged nevus, BRAFV600E mutation in the involuting nevus, and no malignant histopathologic chara

80 PCs), predominantly in proliferating but not involuting or involuted hemangioma.

81 mptive notochord and mesenchyme cells, which involute over the anterior and lateral lips of the blast

82 essed in the presumptive muscle cells, which involute over the posterior lip of the blastopore.

83 : proliferating phase, involuting phase, and involuted phase.

84 ns in the proliferating phase but not in the involuting phase and was shown by immunostaining to resi

85 During the involuting phase, an increase in several IFN-induced gen

86 three distinct stages: proliferating phase, involuting phase, and involuted phase.

87 solated from proliferating phase IH, but not involuting phase, constitutively express E-selectin, a c

88 67% reduction in the apoptotic index in the involuting prostate compared with wild-type animals, imp

89 ped normally during pregnancy; however, they involuted quickly after parturition.

90 Postnatally, the tumor either involutes quickly (i.e., rapidly involuting congenital h

91 Extracellular matrix (ECM) isolated from involuting rat mammary glands was chemotactic for macrop

92 isolated from nulliparous and postlactating (involuting) rat mammary glands differentially modulated

93 As the thymus involutes, reduction in thymocytes and thymic epithelial

94 optosis in epithelial tissues, including the involuting rodent prostate.

95 As the thymus involutes, the diversity of pathogen-specific responses

96 genetic changes, such as marginal zone cells involuting through the blastopore, somitogenic mesoderm

97 ch like that seen in isolation, is likely to involute thus providing spontaneous 'decompression' of t

98 e considered when attempts to rejuvenate the involuted thymus are made.

99 he important question remained whether aged, involuted thymus could also induce tolerance if transpla

100 thymic T-cell precursors, harvested from the involuted thymus exhibit a diminished proliferative pote

101 -specific upregulation of FOXN1 in the fully involuted thymus of aged mice results in robust thymus r

102 We report here that aged, involuted thymus transplanted as a vascularized graft in

103 -PCR analysis of stromal cells purified from involuted thymuses confirmed increased IL-7, SDF-1alpha,

104 n addition, chemokine gene array analysis of involuted thymuses revealed high levels of mRNA expressi

105 can engraft and directly drive the growth of involuted thymuses.

106 tion of lactation, transgenic mammary glands involute to a midpregnant status.

107 These cells involute to join the deeper hypoblast layer where they a

108 Importance: Infantile hemangiomas involute to some extent, but they often leave sequelae t

109 The proportion of normal lobules that were involuted was categorized by an expert pathologist as no

110 BRAF inhibitor therapy is correct: Nevi that involute while a patient is undergoing BRAF V600E inhibi

111 0% of the existing acquired melanocytic nevi involuted, while the remaining nevi did not change.

112 As the thymus involutes with age, the maintenance of peripheral naive