ライフサイエンスコーパス: inwardly

1 ation, the sporophyte dries from the outside inwardly and continues to do so after guard cells die an

2 regions, however with the open state facing inwardly and the closed state facing outwardly.

3 V) express outward K+ current that rectifies inwardly at positive potentials.

4 transmembrane cargo can be sequestered into inwardly budding vesicles for degradation, or can exit t

5 s thaliana) plasma membrane Ca(2+)-permeable inwardly conducting ion channel impairs HR and that this

6 ear-UV photon drives the complex back to the inwardly connected conformer in the repellent signaling

7 by approximately 1.5 units from that of the inwardly connected conformer.

8 auses a Schiff base connectivity switch from inwardly connected to outwardly connected states in the

9 Throughout reversion, MreB localized to inwardly curved regions of the cell, and fluorescent cel

10 pUL31 can inwardly deform membranes by oligomerizing on their inne

11 cause it is spontaneous, self-generated, and inwardly directed (inner thoughts).

12 The likelihood of the inwardly directed arrangement increases when Glu177 resi

13 ntaining electron-rich aromatic walls and an inwardly directed carboxylic acid displayed the necessar

14 A deep cavitand with an inwardly directed carboxylic acid function reacts with s

15 zed by a synthetic cavitand receptor with an inwardly directed carboxylic acid function.

16 tion of a substrate, SERT and DAT display an inwardly directed current comprised of a peak and a stea

17 When inwardly directed functional groups are present, they ca

18 around the guest species; presents them with inwardly directed functionality; and provides a generall

19 esicles, melibiose efflux is inhibited by an inwardly directed gradient of Na(+) or Li(+) and stimula

20 esence of H(+) or Na(+) and stimulated by an inwardly directed Na(+) gradient.

21 ransport of chemically diverse ligands to an inwardly directed proton electrochemical gradient.

22 ical role(s) of mammalian ATP2C1 encoding an inwardly directed secretory pathway Ca2+/Mn2+ pump that

23 rotein- and energy-dependent pathway for the inwardly directed transbilayer movement of lipids other

24 ward transport of di- or tripeptides with an inwardly directed transport of protons.

25 ins, and distinct from previous undefined or inwardly facing arms.

26 to alternate between "outwardly facing" and "inwardly facing" conformations of the transmembrane subs

27 Guard cells collapse inwardly, increase in surface area, and remain perched o

28 o the outwardly located periplasmic side and inwardly located cytoplasmic side.

29 sporter: the changes from an outwardly to an inwardly open conformation during the transport cycle us

30 e whether current conducted by KACh channels inwardly or outwardly rectifies.

31 In general, uracils with inwardly oriented backbones farther away from the dyad c

32 ackbones is 2-10-fold higher than those with inwardly oriented backbones.

33 Because we previously found that inwardly permeating Na ions facilitate dissociation of t

34 ally coordinated to water molecules and five inwardly pointing backbone phosphates.

35 Each end cap includes an inwardly projecting tubular section, which prevents dc f

36 The NE-induced current was inwardly rectified, and the reversal potential was depen

37 er concentration of cGMP and manifests as an inwardly rectified, K+-specific current with a 10.8 pS u

38 ed K(+) channel (KACh) conducts current that inwardly rectifies when activated by some ligands (such

39 ether their macroscopic current outwardly or inwardly rectifies, whereby rectification refers to a ch

40 h that GABABR activation shifts from opening inwardly rectifiying potassium channels (Kir/GIRK) to in

41 ents here, functional voltage-gated (Kv) and inwardly rectifying (Kir) K(+) channel remodeling was ex

42 e concurrent inhibition of barium-sensitive, inwardly rectifying (Kir) potassium channels and activat

43 We investigated the development of inwardly rectifying AMPA receptor-mediated currents and

44 ious results, whole-cell recordings revealed inwardly rectifying AMPAR EPSCs, a hallmark of CP-AMPARs

45 The current was inwardly rectifying and inhibited by Ba(2+) (10 mum) and

46 clic monophosphate showed the presence of an inwardly rectifying and TRAM-34-sensitive K(+) channel i

47 We identified the underlying inwardly rectifying Ca(2+)-dependent I(CRAC) (Ca(2+) rel

48 Inwardly rectifying Ca(2+)-permeable AMPA receptors medi

49 -expressed with STIM1, Orai1 induced a large inwardly rectifying Ca(2+)-selective current with Ca(2+)

50 d orai-1 cDNAs in HEK293 cells induces large inwardly rectifying cation currents activated by ER Ca(2

51 [sulfonylurea receptor (SUR) 1 and potassium inwardly rectifying channel (Kir) 6.1] were expressed se

52 3, member 13 of subfamily J of the potassium inwardly rectifying channel family in all affected indiv

53 activity, but does not alter activity of K+ inwardly rectifying channels (ROMK channels).

54 in neurons and glia, where they form strong inwardly rectifying channels.

55 CLC-2 is a hyperpolarization-activated, inwardly rectifying chloride channel.

56 Like human CFTR, ovine CFTR formed a weakly inwardly rectifying Cl(-) channel regulated by PKA-depen

57 of multiple Kir2 family paralogues, and the inwardly rectifying conductance contributes to the regul

58 izing mutants in the same loop express large inwardly rectifying CRAC current, and two of these exhib

59 ) and (I362T+A419P) generated a constitutive inwardly rectifying current that suggests a sensitivity

60 I-AMPARs as evidenced by polyamine-dependent inwardly rectifying current-voltage (I-V) relationships,

61 ubunits are permeable to calcium and display inwardly rectifying current-voltage relationships, becau

62 0.1 versus 1.2 +/- 0.1 nA at -160 mV) or in inwardly rectifying current-voltage relationships.

63 ve varitint-waddler hair cells as a distinct inwardly rectifying current.

64 hus the SNr receives direct projections from inwardly rectifying gamma-aminobutyric acid (GABA)-ergic

65 pyrimidinium chloride, a specific blocker of inwardly rectifying hyperpolarization-activated current

66 a(2+) (CRAC)-like current while retaining an inwardly rectifying I-V characteristic.

67 N- and C-terminal cytoplasmic domains of inwardly rectifying K (Kir) channels control the ion-per

68 ree A9-elevated molecules [G-protein coupled inwardly rectifying K channel 2 (GIRK2), adenine nucleot

69 In many tissues, inwardly rectifying K channels such as the renal outer m

70 is a critical determinant of G-protein-gated inwardly rectifying K(+) (GIRK) channel activation and u

71 G(i/o) proteins to promote G protein-coupled inwardly rectifying K(+) (GIRK) channel activation.

72 omplexes from Gi/o-gated G protein-regulated inwardly rectifying K(+) (GIRK) channels and delayed GIR

73 ing cascade that activates G-protein-coupled inwardly rectifying K(+) (GIRK) channels and small condu

74 Here we demonstrate that G protein-regulated inwardly rectifying K(+) (GIRK) channels can operate as

75 Gbetagamma-activated inwardly rectifying K(+) (GIRK) channels have distinct g

76 hibitory signaling involving G-protein-gated inwardly rectifying K(+) (Girk) channels in VTA DA neuro

77 The presence of G protein-activated inwardly rectifying K(+) (GIRK) channels near excitatory

78 G protein-activated inwardly rectifying K(+) (GIRK) channels regulate neuron

79 ceptors (GABA(B)-Rs) and G protein-activated inwardly rectifying K(+) (GIRK) channels, both residing

80 nhibit neurons by activating G protein-gated inwardly rectifying K(+) (GIRK) channels, thereby modera

81 G protein-gated inwardly rectifying K(+) (Girk/K(IR)3) channels mediate

82 G-protein-gated inwardly rectifying K(+) (GIRK/Kir3) channel activation

83 G protein-gated inwardly rectifying K(+) (GIRK/Kir3) channels mediate th

84 ve small molecule agonist of G-protein-gated inwardly rectifying K(+) (GIRK/Kir3) channels.

85 nished, suggesting a defect in smooth muscle inwardly rectifying K(+) (KIR) channel function.

86 ified in mouse macrophages: Ba(2+)-sensitive inwardly rectifying K(+) (Kir) channels and 4-aminopyrid

87 ABSTRACT: Inwardly rectifying K(+) (Kir) channels are known to be

88 Inwardly rectifying K(+) (Kir) channels are known to be

89 Inwardly rectifying K(+) (Kir) channels set the resting

90 Inwardly rectifying K(+) (Kir) channels, serving as natu

91 increase in membrane cholesterol suppresses inwardly rectifying K(+) (Kir2) channels that are respon

92 KEY POINTS: Endothelial inwardly rectifying K(+) (Kir2.1) channels regulate flow

93 Endothelial inwardly rectifying K(+) (Kir2.1) channels regulate flow

94 2 receptors activates atrial G protein-gated inwardly rectifying K(+) (Kir3) channels via the betagam

95 In adult retina, aquaporin-4 (AQP4) and inwardly rectifying K(+) (Kir4.1) channels localize to a

96 hannels are present in the lumen or when the inwardly rectifying K(+) channel blocker BaCl(2) is pres

97 perpolarization, increased G-protein-coupled inwardly rectifying K(+) channel current, and attenuated

98 rant localization, and enhanced block of the inwardly rectifying K(+) channel Kir2.1, compared with t

99 18, which encodes a skeletal muscle-specific inwardly rectifying K(+) channel Kir2.6, were reported i

100 etic neuralgia through downregulation of the inwardly rectifying K(+) channel Kir4.1 in satellite gli

101 ia development through downregulation of the inwardly rectifying K(+) channel Kir4.1 in satellite gli

102 Knockdown of the KCNJ15 gene (encoding inwardly rectifying K(+) channel Kir4.2) specifically ab

103 age-gated potassium channel (Kv), as well as inwardly rectifying K(+) channel remodeling, were invest

104 t DNA sequencing of KCNJ10, which encodes an inwardly rectifying K(+) channel, identifies previously

105 at the CaR interacts with and inactivates an inwardly rectifying K(+) channel, Kir4.1, which is expre

106 naptic inhibition in the brain by activating inwardly rectifying K(+) channels (GIRKs) and inhibiting

107 amus through activation of G-protein-coupled inwardly rectifying K(+) channels (GIRKs).

108 most circumstances, outward currents through inwardly rectifying K(+) channels are reduced at more de

109 e that this inhibition requires one of three inwardly rectifying K(+) channels encoded by the C. eleg

110 lial cell Ca(2+)-activated K(+) channels and inwardly rectifying K(+) channels in arterial myocytes.

111 ABA(B)) receptors from their G-protein-gated inwardly rectifying K(+) channels in hypothalamic neuron

112 Comparison of high-resolution structures of inwardly rectifying K(+) channels suggests a model for a

113 BaCl(2), a blocker of inwardly rectifying K(+) channels, also inhibited AITC-i

114 Ethanol activates G protein-gated inwardly rectifying K(+) channels, but the molecular mec

115 man resistance arteries is also regulated by inwardly rectifying K(+) channels.

116 urine colonic muscles express genes encoding inwardly rectifying K(+) channels.

117 nductance KCa1.1, Kv1.2/1.3, Kv7.4, hERG, or inwardly rectifying K(+) channels.

118 t investigations in this unexplored class of inwardly rectifying K(+) channels.

119 does not act via either G-protein-activated inwardly rectifying K(+) conductance (G(IRK)) or hyperpo

120 y is that ICC express the Ba(2+) -sensitive, inwardly rectifying K(+) conductance in colonic muscles.

121 tence of I(OMMKi), a novel voltage-dependent inwardly rectifying K(+) conductance located in the OMM.

122 onic muscles, expressed a Ba(2+) -sensitive, inwardly rectifying K(+) conductance.

123 we pinpointed the lack of the Kir2.1-encoded inwardly rectifying K(+) current (I(K1)) as the single m

124 There was little or no inwardly rectifying K(+) current (I(K1)) in the ED11 atr

125 kephalin (DAMGO) and endomorphin-2 activated inwardly rectifying K(+) current in a concentration-depe

126 ized fashion mainly by a G-protein-activated inwardly rectifying K(+) current.

127 ation of G proteins, and G protein-activated inwardly rectifying K(+) currents.

128 tor-mediated activation of G-protein-coupled inwardly rectifying K(+)-like currents.

129 istent with opening of a G protein-regulated inwardly rectifying K+ (GIRK) channel.

130 hich are believed to block G-protein-coupled inwardly rectifying K+ (GIRK) channels.

131 pette, consistent with a G-protein-activated inwardly rectifying K+ (GIRK) current.

132 Inwardly rectifying K+ (Kir) channels are responsible fo

133 K+ (K(ATP)) channels are hetero-octamers of inwardly rectifying K+ channel (Kir6.2) and sulphonylure

134 calcium currents, increasing G-protein-gated inwardly rectifying K+ channel currents, and presynaptic

135 reduction in GABABR-dependent activation of inwardly rectifying K+ channel currents.

136 periments on two-dimensional crystals of the inwardly rectifying K+ channel KirBac3.1 from Magentospi

137 e frequency, increased GIRK (G-protein-gated inwardly rectifying K+ channel) current, and attenuated

138 ls of the N-, P/Q-, and R-type and G protein inwardly rectifying K+ channels (GIRK) are modulated via

139 G protein-activated inwardly rectifying K+ channels (GIRK) generate slow inh

140 The inwardly rectifying K+ channels were constitutively acti

141 Activities of these inwardly rectifying K+ channels were inhibited by Ba2+ (

142 ppocampal CA1 pyramidal neurons, we recorded inwardly rectifying K+ channels with a single-channel co

143 however, it requires synaptic activation of inwardly rectifying KARs and release of Ca(2+) from stor

144 hannels are heteromultimeric complexes of an inwardly rectifying Kir channel (Kir6.x) and sulfonylure

145 In this, they more closely resemble inwardly rectifying Kir6.2 potassium channels than the m

146 had depolarized resting potentials due to an inwardly rectifying leak conductance formed by the mutan

147 s, including the hyperpolarization-activated inwardly rectifying non-specific cation current (I(h)),

148 polarized potential (e.g. cells with a large inwardly rectifying or Ca(2+)-activated K(+) current), a

149 onstant inhibitory action of ATP on the K(+) inwardly rectifying pore.

150 that alcohol activation of a G-protein-gated inwardly rectifying potassium (GIRK or Kir3) channel is

151 G protein-activated inwardly rectifying potassium (GIRK or Kir3) channels ar

152 lular pathways that regulate G protein-gated inwardly rectifying potassium (GIRK or Kir3) channels ar

153 etween GPCRs, G proteins and G protein-gated inwardly rectifying potassium (GIRK or Kir3) channels.

154 postsynaptic activation of G-protein-linked inwardly rectifying potassium (GIRK) and depression of v

155 REM sleep; likewise, with G-protein-coupled inwardly rectifying potassium (GIRK) channel blockade.

156 Tertiapin Q (TPQ), a G protein-dependent inwardly rectifying potassium (GIRK) channel inhibitor,

157 For example, in excitable cells inwardly rectifying potassium (GIRK) channels are activa

158 G protein-gated inwardly rectifying potassium (GIRK) channels are critic

159 iously, we demonstrated that G-protein-gated inwardly rectifying potassium (GIRK) channels are expres

160 G protein-gated inwardly rectifying potassium (GIRK) channels are import

161 G-protein-coupled inwardly rectifying potassium (GIRK) channels contribute

162 the effect of cholesterol on G protein-gated inwardly rectifying potassium (GIRK) channels expressed

163 onist baclofen to activate G protein-coupled inwardly rectifying potassium (GIRK) channels in hypotha

164 rnalization of M(2)R and G-protein-activated inwardly rectifying potassium (GIRK) channels in neurona

165 s revealed the expression of G protein-gated inwardly rectifying potassium (GIRK) channels in these c

166 latonin receptors activate G-protein-coupled inwardly rectifying potassium (GIRK) channels in Xenopus

167 Activation of G protein-gated inwardly rectifying potassium (GIRK) channels leads to a

168 G protein-activated inwardly rectifying potassium (GIRK) channels mediate sl

169 jor subunits of neuronal G protein-activated inwardly rectifying potassium (GIRK) channels that media

170 eurons by avidin-mediated cross-linking, and inwardly rectifying potassium (GIRK) channels were used

171 G-protein-gated inwardly rectifying potassium (GIRK) channels, which hel

172 ) virally overexpressing G-protein-activated inwardly rectifying potassium (GIRK) channels.

173 rons through activation of G-protein-coupled inwardly rectifying potassium (GIRK) channels.

174 Cl2 , characteristics of a G protein-coupled inwardly rectifying potassium (GIRK) conductance.

175 and D2L receptor-dependent G protein-coupled inwardly rectifying potassium (GIRK) currents.

176 oltage clamp, Dyn-A opened G-protein-coupled inwardly rectifying potassium (GIRK)-like channels on PO

177 The G-protein coupled inwardly rectifying potassium (GIRK, or Kir3) channels a

178 ted by GABA(B) receptors and G protein-gated inwardly rectifying potassium (GIRK/Kir(3)) channels, ho

179 G protein-gated inwardly rectifying potassium (GIRK/Kir3) channels media

180 es D2-receptors on MSNs, G protein activated inwardly rectifying potassium (GIRK2; Kir 3.2) channels

181 G-protein-gated inwardly rectifying potassium (GIRK; also known as Kir3)

182 Here, we show that inwardly rectifying potassium (Irk) channels regulate re

183 G protein-gated inwardly rectifying potassium (K(+)) (Girk/Kir3) channel

184 Although inwardly rectifying potassium (K(IR)) channels are known

185 via the activation of Na(+)/K(+)-ATPase and inwardly rectifying potassium (K(IR)) channels in humans

186 e antiviral immune response by ATP-sensitive inwardly rectifying potassium (KATP) channels.

187 nted during exercise following inhibition of inwardly rectifying potassium (KIR ) channels and Na(+)

188 ilatation that is dependent on activation of inwardly rectifying potassium (KIR ) channels, with a mo

189 The inwardly rectifying potassium (Kir) 2.x channels mediate

190 Nearly all members of the inwardly rectifying potassium (Kir) channel family share

191 ics simulations containing >100 copies of an inwardly rectifying potassium (Kir) channel which forms

192 in human sequence databases) that encodes an inwardly rectifying potassium (Kir) channel, Kir2.6.

193 ypothesized that RH occurs via activation of inwardly rectifying potassium (KIR) channels and Na(+)/K

194 llular polyamines are endogenous blockers of inwardly rectifying potassium (Kir) channels and underli

195 Inwardly rectifying potassium (Kir) channels are charact

196 Inwardly rectifying potassium (Kir) channels are gated b

197 Inwardly rectifying potassium (Kir) channels form gates

198 Control of surface expression of inwardly rectifying potassium (Kir) channels is importan

199 Inwardly rectifying potassium (Kir) channels play an imp

200 Inwardly rectifying potassium (Kir) channels play an imp

201 Inwardly rectifying potassium (Kir) channels regulate mu

202 Inwardly rectifying potassium (Kir) channels were the fi

203 annels are prokaryotic homologs of mammalian inwardly rectifying potassium (Kir) channels, and recent

204 Cholesterol modulates inwardly rectifying potassium (Kir) channels.

205 sphate (PIP(2)) is an activator of mammalian inwardly rectifying potassium (Kir) channels.

206 ive potassium channels, most consistent with inwardly rectifying potassium (Kir) channels.

207 , we show that the voltage dependence of the inwardly rectifying potassium (KIR) conductance activate

208 ular complexes with neuronal G protein-gated inwardly rectifying potassium (Kir3 or GIRK) channels.

209 Expression of this photoinducible inwardly rectifying potassium (PIRK) channel in rat hipp

210 The inwardly rectifying potassium 3.2 (Kir3.2) channel is fo

211 crystallization conditions for a prokaryotic inwardly rectifying potassium channel (>130 different co

212 xpressing rat MOR1 as well G protein-coupled inwardly rectifying potassium channel (GIRK) channel sub

213 ce that reversed at -93 mV, indicative of an inwardly rectifying potassium channel (GIRK) mechanism.

214 KOR-induced tyrosine phosphorylation of the inwardly rectifying potassium channel (GIRK) subunit Kir

215 nal excitability through co-expression of an inwardly rectifying potassium channel (Kir2.1).

216 r-mediated activation of G-protein-activated inwardly rectifying potassium channel (Kir3.X) (GIRK) co

217 multimeric protein complex composed of four inwardly rectifying potassium channel (Kir6.2) and four

218 study, we focused on the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) gene tha

219 e randomly mutagenized the G protein-coupled inwardly rectifying potassium channel 3.2 (GIRK2) bearin

220 xpression of tetanus toxin light chain or an inwardly rectifying potassium channel also inhibits cond

221 mutations in KCNJ6 (GIRK2), which encodes an inwardly rectifying potassium channel and maps to the Do

222 ings of ligand activated G-protein-activated inwardly rectifying potassium channel currents in mouse

223 mutation in the gene encoding the G-protein inwardly rectifying potassium channel Girk2, exhibits a

224 specific amino acid mutations in the Kir2.1 inwardly rectifying potassium channel have been found to

225 Mutations that disrupt function of the human inwardly rectifying potassium channel KIR2.1 are associa

226 use visual system to ectopically express the inwardly rectifying potassium channel Kir2.1 in individu

227 us activity due to the overexpression of the inwardly rectifying potassium channel Kir2.1 in the olfa

228 n of a photoreactive Uaa into the pore of an inwardly rectifying potassium channel Kir2.1.

229 iesterase (PDE) 1C, and PDE9A; and channels: inwardly rectifying potassium channel Kir2.4, transient

230 mediated via the G protein-coupled receptor inwardly rectifying potassium channel Kir3.Our findings

231 Inwardly rectifying potassium channel Kir4.1 is critical

232 The inwardly rectifying potassium channel Kir4.2 is sensitiv

233 The inwardly rectifying potassium channel Kir6.2 assembles w

234 The inwardly rectifying potassium channel Kir6.2 is the pore

235 ng the sulfonylurea receptor 1 (SUR1) or the inwardly rectifying potassium channel Kir6.2, respective

236 P(a) < 0.08), as well as with ATP-sensitive inwardly rectifying potassium channel subunit Kir6.2 (KC

237 t of Gbetagamma on GIRK (G protein activated inwardly rectifying potassium channel) activation.

238 TA neurons, NK receptor activation closes an inwardly rectifying potassium channel, and moreover inhi

239 l, cytoplasmic domain of the G-protein-gated inwardly rectifying potassium channel, K(ir)3.1 facilita

240 ned by mutations in a novel gene encoding an inwardly rectifying potassium channel, Kir2.6.

241 The KCNJ13 gene encodes the inwardly rectifying potassium channel, Kir7.1.

242 igand-induced coupling of MC4R to closure of inwardly rectifying potassium channel, Kir7.1.

243 larke et al. now present 11 structures of an inwardly rectifying potassium channel, providing evidenc

244 ptor-mediated opening of a G-protein-coupled inwardly rectifying potassium channel.

245 d postsynaptic activation of G-protein-gated inwardly rectifying potassium channels (GIRKs) electroph

246 The subfamily of G-protein-linked inwardly rectifying potassium channels (GIRKs) is couple

247 ought to determine whether G protein-coupled inwardly rectifying potassium channels (GIRKs) modulate

248 ave investigated the role of G-protein-gated inwardly rectifying potassium channels (GIRKs), a recent

249 trimers to interact with G-protein regulated inwardly rectifying potassium channels (GIRKs), and we s

250 nd specific members of the G-protein-coupled inwardly rectifying potassium channels (GirKs).

251 ylation, and activation of G protein-coupled inwardly rectifying potassium channels (GIRKs).

252 rated by the activation of G-protein-coupled inwardly rectifying potassium channels (GIRKs).

253 tyrosine phosphorylation of G-protein-gated inwardly rectifying potassium channels (K(ir)3 or GIRK)

254 ated vasodilatation occurs via activation of inwardly rectifying potassium channels (KIR ), and synth

255 consequent upon loss or reduced function of inwardly rectifying potassium channels affecting various

256 ha(i/o)-coupled receptors, G protein-coupled inwardly rectifying potassium channels and adenylate cyc

257 We tested the hypothesis that activation of inwardly rectifying potassium channels and the sodium-po

258 receptors couple via G-proteins to activate inwardly rectifying potassium channels and to inhibit ca

259 Strongly inwardly rectifying potassium channels are blocked by in

260 Regulation of inwardly rectifying potassium channels by intracellular

261 hloroquine and related compounds can inhibit inwardly rectifying potassium channels by multiple poten

262 Inwardly rectifying potassium channels enforce tight con

263 ore, whether Cav-1 regulates the function of inwardly rectifying potassium channels Kir2.1 that play

264 r and its downstream GIRK (G protein-coupled inwardly rectifying potassium channels) channels (IK,Ado

265 -THCs enable CB1-mediated optical control of inwardly rectifying potassium channels, as well as adeny

266 er L-glutamate or expressing G-protein-gated inwardly rectifying potassium channels, hepatic lineage

267 through the activation of G-protein-coupled inwardly rectifying potassium channels.

268 oding Trpv4, Aqp4, and the Kir4.1 subunit of inwardly rectifying potassium channels.

269 iated by the mGlu2 subtype that activates an inwardly rectifying potassium conductance in the dendrit

270 ine-mediated activation of G protein-coupled inwardly rectifying potassium conductance was measured u

271 ing to the activation of a G protein-coupled inwardly rectifying potassium conductance.

272 tion (61%) of KF neurons by activation of an inwardly rectifying potassium conductance.

273 es have postulated an important role for the inwardly rectifying potassium current (I(K1)) in control

274 wo critical ionic current mechanisms are the inwardly rectifying potassium current (I(K1)), which is

275 sarcoplasmic reticulum Ca2+ concentrations, inwardly rectifying potassium current (IK1) density, and

276 emonstrate that NPY specifically enhances an inwardly rectifying potassium current via NPY-Y1 recepto

277 The activation of G protein-coupled inwardly rectifying potassium current was measured using

278 lancing interplay between sodium current and inwardly rectifying potassium current with increasing fi

279 ors by (1) activation of a G protein-coupled inwardly rectifying potassium current, (2) inhibition of

280 types of TH neuron through G-protein coupled inwardly rectifying potassium currents mediated by delta

281 nist baclofen both elicited increases of the inwardly rectifying potassium currents that could be blo

282 G protein-gated inwardly rectifying potassium ion (GIRK/Kir3) channels,

283 ltage-dependent inward rectification of Kir (inwardly rectifying potassium) channels arises from bloc

284 receptor desensitization from a linear to an inwardly rectifying shape, in contrast to their heterome

285 currents in primary hippocampal neurons are inwardly rectifying upon desensitization.

286 in NIH/3T3 cells, full-length rClC-2 yielded inwardly rectifying whole-cell currents with very slow a

287 by submicromolar concentrations of 5-HT, is inwardly rectifying with a reversal potential near the e

288 he current-voltage relationship was slightly inwardly rectifying with a reversal potential of -52 +/-

289 ons from refractory and late SE animals were inwardly rectifying, and philanthotoxin-sensitive; simil

290 of capsaicin-induced mEPSCs, from linear to inwardly rectifying, indicating an increased prevalence

291 We conclude that TRPML1 is an inwardly rectifying, proton-impermeable, Ca(2+) and Fe(2

292 and TRPML3 to be measured and identified as inwardly rectifying, proton-impermeant, Ca(2+)-permeant

293 ontrast to WT TASK3 channels, the current is inwardly rectifying.

294 ), the potassium channel regulator potassium inwardly-rectifying channel Isk-like (IRK2) and ADAM 10

295 g from GABAB receptor to the G protein-gated Inwardly-rectifying K+ (GIRK) channels.

296 potassium, which are largely mediated by the inwardly-rectifying potassium channel Kir4.1, and to tak

297 -targeted CaMKII directly phosphorylates the inwardly-rectifying potassium channel, Kir6.2 (alpha sub

298 e desensitization of the G protein-activated inwardly-rectifying potassium current evoked by receptor

299 of each individual cell protruding from the inwardly regressive arm of the cell-cell interface, and

300 l periphery from where activation propagates inwardly through Ca(2+)-induced Ca2+ release (CICR) from