ライフサイエンスコーパス: iodinate

1 g upon the position of the aryl ring that is iodinated.

2 pharmacological characterization of a novel iodinated 1,4-dihydropyridine KATP channel opener, [125I

3 l)(8),IAmp(9)]-SRIF-Thr-NH(2) (25) was radio-iodinated ((125)I-25) and specifically labeled sst(1)-ex

4 (125)Iodinated 19 selectively binds to sst(4)-transfected cel

5 Next, 135-150 mL of nonionic iodinated (300 mg/mL) contrast material was injected int

6 nd the selective 5-HT2A receptor ligand 123I iodinated 4-amino-N-[1-[3-(4-fluorophenoxy)propyl]-4-met

7 uminum affected the ability of radioactively iodinated Abeta to cross the in vivo BBB.

8 oteins were separated and analyzed for bound iodinated Abeta1-40.

9 e column that bind iodinated inhibin but not iodinated activin.

10 eing protonated to afford protiotriazole, an iodinating agent presumably intercepts the copper(I) tri

11 de and terminal alkyne in the presence of an iodinating agent, with 5-protio-1,2,3-triazole (protiotr

12 ared to that of the wild type as measured by iodinated alpha-bungarotoxin binding ([(125)I]-alpha-BgT

13 s study reports the identification of a lead iodinated analog 5 of the clinical PARP-1 inhibitor olap

14 An iodinated analog of the DNA-minor-groove-binding agent H

15 Moreover, we synthesized novel iodinated analogs of oleate and stearate, and we showed

16 aration and characterization of novel potent iodinated analogs of the NSAIDs indomethacin and suprofe

17 Several iodinated analogues were then synthesized as potential S

18 heir speciation to more toxic brominated and iodinated analogues.

19 h several other unique proteins that surface iodinate and migrate at approximately 15, 20, and 25 kDa

20 Biological activities of these iodinated and brominated meroditerpenes and additional n

21 diatom exudes a diverse mixture of volatile iodinated and brominated metabolites including the natur

22 However, safety concerns limit the use of iodinated and gadolinium (Gd)-based CT and MRI contrast

23 < 1.019 g/ml) from normal mouse plasma were iodinated and injected into normal C57BL/6 mice.

24 studied after intravenous administration of iodinated and tungsten cluster contrast media.

25 These antibodies were iodinated, and their clearance was studied in severe com

26 promote the formation of toxic brominated-, iodinated-, and nitrogen disinfection byproducts during

27 ticle Imaging (MPI), to replace X-ray and CT iodinated angiography, especially for CKD patients.

28 We tested the ability of iodinated annexin V to bind apoptotic cells in vitro usi

29 is investigation was to develop a method for iodinating annexin V that would be suitable for the in v

30 Coincubation of membranes with iodinated antagonist and an excess of unlabeled vasopres

31 ently described the in vivo properties of an iodinated anti-p185HER2 engineered antibody fragment [mi

32 ntibodies are retained longer in tumors than iodinated antibodies, leading to their increased use for

33 Iodinated AOMK ligands are suitable in vitro probes for

34 Iodinated apoE was consistently found in the Golgi fract

35 Receptor function was assessed by uptake of iodinated asialo-orosomucoid, immunoglobulin (Ig) A1, an

36 to those of synthetic peptides that had been iodinated at tyrosine.

37 The radiodiagnostic hypoxic markers beta-D-iodinated azomycin galactopyranoside (IAZGP) and [99mTc]

38 rbazone) and approach those of beta-D-(125)I-iodinated azomycin galactopyranoside, the optimal hypoxi

39 were prepared using Pd-mediated coupling of iodinated base derivatives with a deoxyribose precursor.

40 h were identified as Cys315 and Cys318 using iodinated beta-(4-hydroxyphenyl)ethyl maleimide.

41 Similarly, iodinated biologically active proteins (e.g., thrombin)

42 values were not significantly different from iodinated bitistatin, but uptakes were higher than other

43 The binding of iodinated botulinum toxin type B to nerve membranes was

44 Our results indicate that iodinated bovine serum albumin is removed from the circu

45 Radio-iodinated bovine serum albumin was injected into Cav-1-d

46 ndoplasmic reticulum subfractions with radio-iodinated calreticulin showed specific associations with

47 rmal in respect of superoxide production and iodinating capacity, are unable to resist staphylococcal

48 h N-iodosuccinimide (NIS) to yield the ortho-iodinated carbamate, 1e.

49 Using iodinated cation independent MPR as a probe in a Western

50 Two novel iodinated CCK1R- and CCK2R-selective 1,4-benzodiazepine

51 1, HIV-2, and SIV can compete for binding of iodinated chemokine to CCR5.

52 re used to study binding and transcytosis of iodinated Clostridium botulinum neurotoxin serotypes A,

53 s administration of high-dose low-osmolarity iodinated CM appears safe in patients without renal dysf

54 The iodinated compound 11d was able to displace the referenc

55 The iodinated compound, I-17alpha-CH3-DHT (3), with the high

56 g, and biological profile of a new series of iodinated compounds for potential translation to the cor

57 1 receptor, preserves renal blood flow after iodinated contrast administration and has shown promise

58 fficient large-scale synthesis of a cationic iodinated contrast agent (CA4+) is described for imaging

59 and 0% to 6.25% and 93.75% for both), and an iodinated contrast agent and saline (7.6-1.6 mg per mill

60 A thickened solution of an iodinated contrast agent calibrated with a clinical mult

61 anced abdominal scan, iobitridol, a nonionic iodinated contrast agent containing 350 mg of iodine per

62 was assigned to a corresponding time-varying iodinated contrast agent to create the contrast material

63 cted with a solution containing gadodiamide, iodinated contrast agent, and gelatin.

64 mages acquired after administration of a 35% iodinated contrast agent, there was a statistically sign

65 digital mammography after administration of iodinated contrast agent.

66 distinguish gold nanoparticles (AuNP) and an iodinated contrast agent.

67 Although iodinated contrast agents are relatively safe and widely

68 Nonionic iodinated contrast agents can be divided into monomeric,

69 The application of iodinated contrast agents during diagnostic x-ray proced

70 is and evaluation of a new class of cationic iodinated contrast agents for the imaging of cartilage u

71 al times points after injections of AuNP and iodinated contrast agents.

72 ts in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-

73 injury as it relates to patients undergoing iodinated contrast exposure during critical illness.

74 Use of iodinated contrast for vascular imaging can be associate

75 MRI/A avoids the risks of arterial puncture, iodinated contrast load, and radiation exposure, while p

76 Injection of iodinated contrast material (< or = 100 mL) is tailored

77 veset trisodium) diluted in either saline or iodinated contrast material (50% and full-strength iohex

78 In 50 patients, 150 mL of 60% iodinated contrast material (iohexol or iothalamate megl

79 Group 3 (n = 22) ingested nonionic iodinated contrast material (iohexol) with a concentrati

80 (n = 21) ingested 10-mL aliquots of nonionic iodinated contrast material (iopromide) with a concentra

81 ompartments of a CT phantom were filled with iodinated contrast material diluted to attain attenuatio

82 Intravenous low-osmolality iodinated contrast material had a significant effect on

83 Nonionic iodinated contrast material in conjunction with a hypero

84 mputed tomographic (CT) images obtained with iodinated contrast material in the late 1970s.

85 was used for injection of up to 1,000 mL of iodinated contrast material into one pelvic extraperiton

86 Intravenous low-osmolality iodinated contrast material is a nephrotoxic risk factor

87 suggests the need to consider the effect of iodinated contrast material on the organ doses to patien

88 le in patients with a history of reaction to iodinated contrast material or renal insufficiency.

89 rattenuation classified at dual-energy CT as iodinated contrast material staining (n = 20, 71%), hemo

90 al-energy CT can help differentiate ICH from iodinated contrast material staining with high sensitivi

91 viously undergone nephrectomy, 100 mL of 60% iodinated contrast material was injected at 3 mL/sec (gr

92 traarterial or intravenous administration of iodinated contrast material were evaluated by using dual

93 NGAL depicted CIN in patients who received iodinated contrast material within 8 hours of contrast m

94 After intravenous administration of iodinated contrast material, a 22-gauge needle was inser

95 canning duration, scanning coverage, dose of iodinated contrast material, and mean aortoiliac attenua

96 After injection of 0.2 or 0.4 mL of iodinated contrast material, six rats with mammary adeno

97 cently received intraarterial or intravenous iodinated contrast material.

98 ropathy, as compared with similar volumes of iodinated contrast material.

99 cal polypropylene bottle filled with diluted iodinated contrast material.

100 Nine of these 12 patients received iodinated contrast material.

101 m without the need for ionizing radiation or iodinated contrast material.

102 patients after intravenous administration of iodinated contrast material.

103 to development of post-CT AKI, regardless of iodinated contrast material.

104 ter placement, cavography was performed with iodinated contrast material; these images were compared

105 Nonimmediate hypersensitivity reactions to iodinated contrast media (CM) are common.

106 a well-documented side effect of the use of iodinated contrast media (ICM) administered intravenousl

107 f suspect screening for the detection of six iodinated contrast media (ICM) and their phototransforma

108 Iodinated contrast media (ICM) are commonly administered

109 ter feeding the post-treatments consisted of iodinated contrast media (ICM).

110 n critically ill patients commonly depend on iodinated contrast media and consequently pose the risk

111 nd coronary/vascular interventions depend on iodinated contrast media and consequently pose the risk

112 efined criteria, suggesting that intravenous iodinated contrast media may not be the causative agent

113 celerated hyperthyroidism after injection of iodinated contrast media to evaluate a left hemipelvis m

114 s of ADEs submitted were reviewed for use of iodinated contrast media.

115 s over 80% of the load was due to persistent iodinated contrast media.

116 owing intravenous injection of 174-185 mL of iodinated contrast medium (300 mg iodine per milliliter)

117 Administration of oral iodinated contrast medium does not significantly improve

118 With only 25 mL of iodinated contrast medium focused on the arterial phase,

119 or 69,657 intravenous injections of nonionic iodinated contrast medium for computed tomographic exami

120 xic effect of monomeric nonionic low-osmolar iodinated contrast medium in ICU patients with multiple

121 ere included (20% more than once), before an iodinated contrast medium infusion (contrast inclusions,

122 or before an intrahospital transfer without iodinated contrast medium infusion (control inclusions,

123 Contrary to iodinated contrast medium infusion (odds ratio, 1.57; 95

124 ontrol inclusions, matched on propensity for iodinated contrast medium infusion, the incidence of acu

125 ctors for acute kidney injury, regardless of iodinated contrast medium infusion.

126 Liu et al (1) have shown that iodinated contrast medium preferentially vasoconstricts

127 Extravasation of nonionic iodinated contrast medium results only rarely in moderat

128 Among contrast inclusions, iodinated contrast medium-associated acute kidney injury

129 ration Spontaneous Reporting System, data on iodinated contrast medium-related deaths after LOCM beca

130 vasations of intravenously injected nonionic iodinated contrast medium.

131 paration or a standard preparation plus oral iodinated contrast medium.

132 d dispersion of intravascularly administered iodinated contrast medium.

133 Infusion of saline/iodinated contrast mixture excluded perforation and ensu

134 patients with virtual colonoscopy using oral iodinated contrast preceding conventional colonoscopy.

135 One quarter of all iodinated contrast X-ray clinical imaging studies are no

136 (2.5%) patients, it was necessary to perform iodinated contrast-enhanced cavography before filter dep

137 parison of cavograms obtained with CO(2) and iodinated contrast-enhanced material showed the caval si

138 omponents in the ER membrane and lumen using iodinated cross-linkable peptide derivatives.

139 contrast agents compares very favorably with iodinated CT contrast agents.

140 Compared to [125I]-31, iodinated cyclized amide derivatives [125I]-21 and [125I

141 e unfavorable properties displayed for these iodinated cyclized amide derivatives for in vivo biodist

142 hocytes, and that incubation of T cells with iodinated CyPA, followed by chemical cross-linking, resu

143 For all test compounds, iodinated daughter products are rapidly produced when fr

144 For iodinated derivative 5, maintaining potency in TP recept

145 high affinity, KD approximately 3 nM, for an iodinated derivative of glyburide, an anti-diabetic sulf

146 actions were successfully achieved using our iodinated derivatives.

147 effective at inhibiting the binding of radio-iodinated diferric glycosylated hTF from a commercial so

148 after 24 h) was transformed to known organic iodinated disinfection byproducts (DBPs) of low molecula

149 mitigate the formation of potentially toxic iodinated disinfection byproducts (I-DBPs) while control

150 Analysis of crystals with iodinated DNA shows that the operator is uniquely positi

151 py of viable V79 cells demonstrated that the iodinated dye stained the nuclei with avidity similar to

152 detected only in cases where brominated and iodinated dyes were photo-oxidized.

153 Our results suggest that iodinated Ex(9-39)NH2 may be a promising tracer for imag

154 Iodinated factor XI-N248 binds to activated platelets wi

155 compared tissue uptake and metabolism of two iodinated fatty acid analogs BMIPP and 15-(p-iodophenyl)

156 KD (620 nM) at the cloned NTR-1, NT27-I (the iodinated form of NT27) exerted a potent hypothermic eff

157 Binding of purified iodinated gonococcal LOS identified a protein of molecul

158 of excess unlabelled LOS blocked binding of iodinated gonococcal LOS.

159 We characterized a new iodinated, high affinity, linear V1a vasopressin antagon

160 These iodinated humic acids are stable with respect to photoly

161 Iodinated IL-4 delta 2 was found to bind specifically to

162 /safety profile comparable to or better than iodinated imaging agents.

163 The radio-iodinated imidazopyridine derivative (123)I-ABC577 was d

164 ldiynes 1 with one equivalent of iodine gave iodinated indeno[1,2-c]chromenes 3 in good chemical yiel

165 cytes from patients with lepromatous leprosy iodinate ingested bacteria normally.

166 pinal ganglion and trigeminal ganglion-bound iodinated inhibin A.

167 oteins were eluted from the column that bind iodinated inhibin but not iodinated activin.

168 formation may occur via a transiently stable iodinated intermediate rather than by direct single-elec

169 roalkynyl- analogues, prepared from a common iodinated intermediate via Sonogashira coupling reaction

170 t methods because it does not produce stable iodinated intermediates.

171 percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber

172 rauma, or both were imaged with simultaneous iodinated intravenous and bismuth subsalicylate enteric

173 n solution phantoms and in a rabbit in which iodinated intravenous and bismuth subsalicylate oral con

174 e were 57 adverse events related to nonionic iodinated intravenous contrast material in 12,494 consec

175 tero exposure to water-soluble, low-osmolar, iodinated intravenous products, such as iohexol, is unli

176 1-42) and showed that, after i.v. injection, iodinated JV-1-42 (131I-JV-1-42) enters the brain intact

177 ichoic acid, and hsp60 also competed against iodinated L-37pA.

178 A-I, and L-37pA efficiently competed against iodinated L-37pA.

179 These results were confirmed by iodinated laminin and merosin overlay of electrophoretic

180 The binding of iodinated LARC, the chemokine ligand for CCR6, to CCR6-t

181 tas of mice by measuring the accumulation of iodinated LDL particles in the arterial wall.

182 , foam cell content, and aortic pool size of iodinated LDL particles of aortic atherosclerotic plaque

183 weeks before injection with preparations of iodinated LDL particles.

184 ent despite an unchanged pool size of aortic iodinated LDL particles.

185 synthesis and properties of a high-affinity iodinated ligand that selectively binds the alpha/delta

186 low background activity associated with this iodinated ligand.

187 Radioimmunoassay (RIA) employing iodinated ligands represents a popular measurement metho

188 These data indicate that the new iodinated ligands showed high binding affinities and bet

189 The iodinated linear vasopressin antagonist therefore allows

190 Model peptides blocked uptake of iodinated LPS in both mock transfected and CLA-1-overexp

191 s with the cells was quantitated using radio-iodinated LPS.

192 odal approach using a single fluorinated and iodinated melanin-targeting structure and offering both

193 a conventional contrast material and a novel iodinated MMCM.

194 urrent CT contrast agents are based on small iodinated molecules.

195 dose, AHF was measured by dilution of radio-iodinated monkey albumin perfused through the anterior c

196 nous injection of a contrast agent formed of iodinated nanoparticles dispersed with surfactant.

197 The iodinated nature of this compound offers additional util

198 nd after intravenous bolus administration of iodinated non ionic contrast agent; CT images demonstrat

199 from pulmonary embolization of Lipiodol, an iodinated oil commonly used during the procedure.

200 5'-Iodinated oligonucleotides (prepared by an automated cyc

201 mb ischemia, for which the administration of iodinated or gadolinium-based contrast agents is contrai

202 mmatory drugs (10.2%), acetaminophen (3.9%), iodinated or magnetic resonance imaging contrast media (

203 ted when exposed to combustion of either the iodinated or noniodinated powders.

204 halogenated organic compounds, particularly iodinated organic molecules, are absent from inland natu

205 order rate constants for the chlorinated and iodinated oxidants.

206 Cleavage of iodinated PA containing the sequence RKKR or RAAR was de

207 Furthermore, we provide evidence for iodinated PBDEs and direct attention toward the contribu

208 e an antisense imaging agent comprised of an iodinated peptide nucleic acid (PNA) conjugated to a mon

209 irmed by experiments in which the binding of iodinated peptide was blocked by unlabeled Qdm and not b

210 tatin retains the functional activity of the iodinated peptide, has higher DVT and PE uptakes than ot

211 tides labeled with lanthanides-MeCAT-IA, and iodinated peptides, respectively, were obtained.

212 In vivo, tissue distribution of iodinated, poorly oxidized beta-methyliodophenyl pentade

213 Binding of the di-iodinated probe was saturable (K(d) = 200 nM) and compet

214 trate enantiomers into enantiomerically pure iodinated products.

215 Ligand binding studies with iodinated prokineticin revealed the presence of a high-a

216 vine FGF-1 did not reduce the ability of the iodinated protein to bind to heparin.

217 did not restore the heparin affinity of the iodinated protein.

218 d hormone/PTHrP receptor-mediated binding of iodinated PTHrP or steady-state receptor message by Nort

219 ding characteristics of the Mpl receptor, we iodinated purified 70-kD recombinant human Tpo using the

220 Iodinated purified fimbriae also bound to the same two e

221 tibodies were used to inhibit the binding of iodinated purified fimbriae as well as the binding of P.

222 on intact cells, we show specific binding of iodinated Qdm peptide to Qa-1b expressing cells.

223 the interaction-binding between a series of iodinated quinazolinone derivatives and human placental

224 ptor autoradiographic technique utilizing an iodinated radioligand [(125)I]ZM 241385, which has great

225 Although iodinated radiopharmaceuticals usually contain a small q

226 sue sections by in situ ligand binding using iodinated recombinant human inhibin A and 125I-labeled r

227 Iodinated recombinant mouse TSP2 bound to NIH 3T3 cells

228 romide and its metabolites revealed that the iodinated ring remains intact and that minor transformat

229 Mono-iodinated RLF tracers were produced and characterized sp

230 p to 86% greater in cells than with directly iodinated RS7.

231 tly (with Texas Red) tagged SAA (TxR-SAA) or iodinated SAA ((125)I-SAA).

232 A from the cell cultures was cleaving scHGF, iodinated scHGF was added to intact cells in the presenc

233 (125)RISA (radio-iodinated serum albumin) was used as an intraperitoneal

234 IC, we infused mice intravenously with radio-iodinated SIC made of OVA and rabbit IgG anti-OVA.

235 , and 15 mm in diameter) filled with various iodinated solutions to simulate hypervascular liver lesi

236 ne to simulate the unenhanced state and with iodinated solutions to simulate the three levels of rena

237 six simulated lesions filled with different iodinated solutions were calculated.

238 influence of secretagogues on the binding of iodinated SP-A to alveolar type II cells.

239 We have tuned the half-lives of the iodinated structures from 3 h to 3 days.

240 cycloheximide markedly decreased binding of iodinated systemin to the cells, indicating that the bin

241 to small molecules and proteins and generate iodinated tetrazines for bioorthogonal chemistry has bee

242 osine into beef thyroid slices, isolated and iodinated the [14C]thyroglobulin (Tg I), separated its N

243 nnyl)benzoate (Boc-SGMTB, 3) was first radio-iodinated to [*I]Boc-SGMIB, a derivative of [*I]SGMIB wi

244 work shows that copper(I) triazolide can be iodinated to afford iodotriazoles.

245 llicular compartment, where thyroglobulin is iodinated to form the protein precursor to T(4) and T(3)

246 s from purified hydrogenosomes obtained from iodinated trichomonads confirmed the specific surface la

247 ed HAN and regulated THM formation; however, iodinated trihalomethane formation was observed at lower

248 peciation toward formation of brominated and iodinated trihalomethanes (THMs) and brominated haloacet

249 These compounds can be lithiated or iodinated under electrophilic conditions without decompo

250 MORAb-004 was directly iodinated with (125)I and (124)I, and in vitro binding a

251 Annexin V was iodinated with (125)I using 2 different techniques: dire

252 These products could then be iodinated with chloramine T to give the 125I-derivatives

253 sistance to biological wastewater treatment, iodinated X-ray contrast media (ICM) have been detected

254 The transformation of the iodinated X-ray contrast media (ICM) iopamidol, iopromid

255 cals (antibiotics, antimycotics, antivirals, iodinated X-ray contrast media, antiinflamatory, cytosta

256 sport and biochemical transformations of the iodinated X-ray contrast medium (ICM) iomeprol were stud

257 The iodinated X-ray contrast medium diatrizoate is known to

258 This result was identical for both surface-iodinated YT cells and immunoprecipitates that were prob

259 ds based on Sonogashira cross-coupling of an iodinated zinc phthalocyanine with acetylenic bombesin o