ライフサイエンスコーパス: iodination

1 is the first use of N-iodoamide for C-H bond iodination.

2 d intrinsic ability to form T3 upon in vitro iodination.

3 cinimide followed by the silver(I)-catalyzed iodination.

4 e UK, which has no programme of food or salt iodination.

5 similar to that of the electronic effects in iodination.

6 C) lost its binding affinity to heparin upon iodination.

7 and tested for their heparin affinity after iodination.

8 F-1 retained its heparin affinity even after iodination.

9 iO(1.5)](n) (n = 8, 10, 12) via ICl-promoted iodination (-40 to -60 degrees C) with overall yields of

10 loped different protocols for the arylation, iodination, acetoxylation, and olefination of these subs

11 9-dicarboxylates followed by decarboxylative iodination affords a 2,9-diiododipyrroketone which gives

12 The hydrogen-atom transfer mechanism for C-H iodination allows C-H oxidation to proceed with minimal

13 ne-directed, Pd(II)-catalyzed sp(3) C-H bond iodination and acetoxylation reactions as reported in pr

14 Surface iodination and Man-6-P/IGF-II receptor affinity chromato

15 r was achieved in one pot through sequential iodination and O-arylation of phenol under mild reaction

16 iiodopropenyl phosphonate, via electrophilic iodination, and alpha-fluoro-gamma-amino-alpha,beta-unsa

17 permeable to dye and accessible to tyrosine iodination, and have aberrant collagen protein expressio

18 Using surface iodination, anti-CD44 immunoprecipitation and immuno-bin

19 Plot shapes for iodination are compared to those of other reactions, suc

20 close proximity, in which case the extent of iodination at each residue may be difficult to determine

21 uantitative evaluation of the likelihood for iodination at each site.

22 rosine residue, similar chemistry occurs via iodination at histidine.

23 f the 2-amino group of 10 and regioselective iodination at the 5-position followed by palladium-catal

24 a strong Pd-DG interaction increases the EC iodination barrier and reduces the I-I oxidative additio

25 ion is believed to take place via an in situ iodination-based oxidative elimination of formaldehyde.

26 nd sst(4)-selective ligands amenable to (125)iodination, could not be achieved satisfactorily.

27 lyl/crotyl/alkoxyallylboration-hydroboration-iodination-cyclization reaction sequence.

28 Pd-catalyzed ortho-C-H iodination directed by a weakly coordinating amide auxil

29 ch for the determination of chlorination and iodination disinfection byproducts based on solid-phase

30 echnique was applied to the determination of iodination disinfection byproducts from individual precu

31 Negishi carbometalation-iodination established the (E)-iodoalkene, and addition

32 n) is essential to deliver Tg to its site of iodination for thyroxine biosynthesis.

33 m 2-(benzyloxy)-5-deoxyascorbic acid (15) by iodination (I2, PPh3, Imd), iodo substitution with lithi

34 via a three-step protocol consisting of (i) iodination, (ii) zincation followed by Pd-catalyzed viny

35 d be prevented by pretreatment of cyt c with iodination, implying that the tyrosine residue of cyt c

36 ing dihydropyrazoles undergo dehydration and iodination in the presence of ICl and Li2CO3 at room tem

37 y of deiodination from T4 We found that upon iodination in vitro, de novo T3 formation in TG was decr

38 same glands and processed similarly, without iodination in vitro.

39 via palladium-catalyzed enantioselective C-H iodination in which one of the enantiomers of a racemic

40 n and mass spectrometry to localize sites of iodination in whole proteins.

41 Site specific identification of the sites of iodination is important for many of these uses.

42 The reaction proceeds through sequential iodination, Kornblum oxidation, and amidation in one pot

43 The reaction involves consecutive iodination, Kornblum oxidation, and intramolecular amida

44 The invertive desilylative iodination leads to the total synthesis of isodomoic aci

45 benzyl-1H-imidazole and a regioselective C-4 iodination method to acquire starting material for our a

46 n lead to inactive peptides due to excessive iodination, nonspecific iodination, or oxidative damage

47 pharmaceutical formulation demonstrated that iodination of a conserved tyrosine (Tyr(B26)) enhances k

48 which a 5-iodo-1,2,3-triazole is formed via iodination of a copper(I) triazolide intermediate by the

49 Iodination of a lone tyrosine residue in each sequence d

50 the palladium(II)-catalyzed bromination and iodination of a variety of alpha-hydrogen-containing car

51 ad proceeding by electrophilic selenation or iodination of a vinyl boronate complex followed by stere

52 e of palladium(II)-catalyzed beta-C(sp(3))-H iodination of a wide range of ketones using a commercial

53 C-H chlorination and bromination, the direct iodination of alkanes represents a great challenge.

54 Direct iodination of annexin V on tyrosine residues is a poor t

55 A mild and rapid method for the iodination of arenes that utilizes silver(I) triflimide

56 The facile iodination of aromatic compounds under mild conditions i

57 henol derivatives and allowed the late-stage iodination of biologically active compounds such as PIMB

58 Iodination of different aromatic compounds with this rea

59 Iodination of either 2-(1'-hydroxy-6'-methylphen-2'-yl)-

60 Rh(III)-catalyzed selective bromination and iodination of electron-rich heterocycles is reported.

61 A one-pot, high-yielding iodination of hydroxypyridines and hydroxyquinolines is

62 etected at the cell surface as determined by iodination of intact cells and the lack of susceptibilit

63 od has been developed for selective benzylic iodination of methylarenes.

64 te ([*I]SGMIB), an agent useful in the radio-iodination of proteins, including monoclonal Abs, and pe

65 be delivered at the cell surface to catalyze iodination of secreted thyroglobulin.

66 3-alkylation, N3-borane complexation, and C4-iodination of some of these were investigated in order t

67 nversely, de novo T3 that can be formed upon iodination of TG secreted from PCCL3 (rat thyrocyte) cel

68 rene 6 has been achieved by copper-catalyzed iodination of the 1,3-bistriflate ester 2a of p-tert-but

69 ransformations was lithiation and subsequent iodination of the 4-(2,2,2-trifluoro-1-hydroxyethyl)pyra

70 eliminary mechanistic studies reveal in situ iodination of the amine as the putative mode of activati

71 t, shown in Scheme 1, involves diazotization/iodination of the corresponding aminofluoresceins.

72 The electrophilic aromatic iodination of the corresponding trimethylstannyl interme

73 An efficient regioselective iodination of the Fischer-Borsche ring has been achieved

74 estigated whether iodine replacement through iodination of the irrigation water would decrease infant

75 cyclic chelation in a nonpolar solvent, (3) iodination of the naphthyridine at C(3), and (4) CuI-med

76 If iodination of the protein is carried out under natively

77 low) up to 244), coupled with the subsequent iodination of the remaining enantiomerically enriched st

78 rior to the copper iodide catalyst, as ortho-iodination of the substrates could be prevented.

79 Thyroidal T4 production results from iodination of thyroglobulin (TG) at residues Tyr(5) and

80 Iodination of tyrosine residues in proteins has many use

81 iodination with IODO-BEADS, resulting in the iodination of tyrosine residues; and use of the Bolton-H

82 s capable of a direct and efficient C-H bond iodination of various cyclic and acyclic alkanes providi

83 Traditional methods of iodination often lead to inactive peptides due to excess

84 an betaPP-wt cells after either cell surface iodination or [35S]methionine labeling, indicating that

85 Electrophilic iodination or bromination of a 5,10-diaryl-substituted c

86 Iodination or bromination of a free base 5,10-diaryloxoc

87 des due to excessive iodination, nonspecific iodination, or oxidative damage to the peptide.

88 1, upon oxidation to cysteic acid during the iodination procedures, would interact with lysine-126 an

89 The iodination proceeds under mild conditions, and the produ

90 Furthermore, the one-pot direct iodination process is extended to the concise synthesis

91 To this end, regioselective iodination protocols were developed for 7-deaza-2'-deoxy

92 general, and practical ortho bromination and iodination reaction of different classes of aromatic com

93 An efficient iodination reaction of electron-deficient heterocycles i

94 An enantioselective C-H iodination reaction using a mono-N-benzoyl-protected ami

95 A stereochemically divergent desilylative iodination reaction was developed to convert the cycliza

96 nylglycine-derived 1,6-enyne, a desilylative iodination reaction, as well as an alkenyl-alkenyl silic

97 ting the missing version of the Wohl-Ziegler iodination reaction.

98 tereospecific chlorination, bromination, and iodination reactions.

99 ues was either conjugated with (124)I via an iodination reagent or coupled with deferoxamine (Df) and

100 roiodate (1, TMADCI) as a mild and efficient iodination reagent was prepared.

101 d 65-98 MBq (1.7-2.6 mCi) of (124)I using an iodination reagent.

102 e, because they are the most prominent early iodination sites in this part of thyroglobulin, and beca

103 TG synthesis, iodination, storage in follicles, and degradation contro

104 lated thyrocytes alters the structure of the iodination substrate in a way that enhances de novo T3 f

105 Here we report a low-cost decarboxylative iodination that occurs simply from readily available ben

106 ves binding up to 1 order of magnitude after iodination through interactions that can be interpreted

107 atalyzes bromination but not fluorination or iodination; (v) SgcC3 can utilize both (S)- and (R)-beta

108 The efficiency of IODO-BEADS iodination was just below 30%; with the Bolton-Hunter pr

109 iculum (ER) before its export to the site of iodination, where it serves as the precursor for thyroid

110 131S) was able to bind to heparin even after iodination while bovine FGF-1 (S131C) lost its binding a

111 (125)I using 2 different techniques: direct iodination with IODO-BEADS, resulting in the iodination

112 hanistic details of the Pd(II)-catalyzed C-H iodination with molecular I2 as the sole oxidant.

113 th olefins, hydroarylation with alkynes, and iodination with N-iodosuccinimide is reported here.

114 g was with (125)I or (131)I, by conventional iodination; with (111)In using the chelator benzyl-dieth

115 In addition, the iodination works on both 2- and 4-hydroxypyridines and -

116 .d.) of 91%+/-8% was achieved, comparable to iodination yields.