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1 thyronine and elevated levels of reverse Tri-iodothyronine.
2  DLK1-DIO3 (delta-like 1 homolog-deiodinase, iodothyronine 3) cluster on human chromosome 14.
3  due in part to decreased activity of type I iodothyronine 5'-deiodinase (5' D-I), the hepatic enzyme
4 xine dynamically regulates levels of type II iodothyronine 5'-deiodinase (5'D-II) by modulating enzym
5 f genes: (A). clone MGC: 19375; (B). Type II iodothyronine 5'-deiodinase (D2); (C). reduced expressio
6 abeling of p29 in astrocytes lacking type II iodothyronine 5'-deiodinase activity and examined the ef
7 ow that cAMP-dependent activation of type II iodothyronine 5'-deiodinase activity results from the sy
8  encodes an essential subunit of rat type II iodothyronine 5'-deiodinase and 2) identify the first no
9                                      Type II iodothyronine 5'-deiodinase catalyzes the bioactivation
10 n sequence elements from the GPX1 and type I iodothyronine 5'-deiodinase genes in RNA electrophoretic
11                                      Type II iodothyronine 5'-deiodinase is an approximately 200-kDa
12   In astrocytes, thyroxine modulates type II iodothyronine 5'-deiodinase levels by initiating the bin
13 ired to express catalytically active type II iodothyronine 5'-deiodinase.
14 aracterized by low levels of circulating tri-iodothyronine and elevated levels of reverse Tri-iodothy
15 relative concentrations of three circulating iodothyronines, as well as neurological abnormalities, i
16 y displacing an autoinhibitory loop from the iodothyronine binding site.
17 nied by free thyroxine and total or free tri-iodothyronine concentrations, which are raised (overt hy
18 ormone or free tri-iodothyronine, free tetra-iodothyronine decreased by 19% (23 to 16) in the 50 mug
19 ry, there is a persistent increase in type 2 iodothyronine deiodinase (D2) activity in the mediobasal
20  the tadpole catalyzed by the enzyme type II iodothyronine deiodinase (D2) and the local effect (cell
21                           The enzyme type II iodothyronine deiodinase (D2) converts thyroxine (T4) to
22             Although a putative human type 2 iodothyronine deiodinase (D2) gene (hDio2) encoding a si
23                                       Type 2 iodothyronine deiodinase (D2) is a recently cloned selen
24                                       Type 2 iodothyronine deiodinase (D2) is a selenoenzyme, the pro
25                                   The type 2 iodothyronine deiodinase (D2) is an integral membrane ER
26                                   The type 2 iodothyronine deiodinase (D2) is critical for the intrac
27          The cAMP-responsive gene for type 2 iodothyronine deiodinase (D2), an intracellular enzyme t
28 limiting steps in the inactivation of type 2 iodothyronine deiodinase (D2).
29 inactivating (TH-inactivating) enzyme type 3 iodothyronine deiodinase (D3) is an oncofetal protein th
30                                       Type 3 iodothyronine deiodinase (D3), the thyroid hormone-inact
31 xpresses extremely high levels of the type 3 iodothyronine deiodinase (D3), which inactivates thyroxi
32  TH (i.e. triiodothyronine (T3)), and type 1 iodothyronine deiodinase (DIO1) mRNA expression.
33 H was caused by reduced expression of type 2 iodothyronine deiodinase (Dio2), a gene that is required
34 in-releasing hormone receptor (Trhr), type 2 iodothyronine deiodinase (Dio2), mediator complex subuni
35 se 1 (Ppp1r3c, Ppp1r3d, Ppp1r3g) and type II iodothyronine deiodinase (Dio2).
36 the LV of males by ~22% and increased type 3 iodothyronine deiodinase (DIO3) mRNA expression in both
37 one peroxidase 3 (GPx3; <86.9 ng mL(-1)) and iodothyronine deiodinase (IDI; <64.8 ng mL(-1)), respect
38  and the role played by polymorphisms in the iodothyronine deiodinase 1 (DIO1) and 2 (DIO2) genes in
39 we found that the activity and expression of iodothyronine deiodinase 2 (DIO2), an enzyme that activa
40  of the sensitive-period mediator gene DIO2 (iodothyronine deiodinase 2) in the right retina.
41 iodothyronine (T3) concentrations and type 1 iodothyronine deiodinase DIO1 mRNA expression in the non
42 n to be mediated through the upregulation of iodothyronine deiodinase DIO2, a critical modulator of t
43 lenium, which is at the active center of the iodothyronine deiodinase enzymes that catalyze the conve
44 by the action of activating and inactivating iodothyronine deiodinase enzymes.
45 e delta-like homolog 1 gene and the type III iodothyronine deiodinase gene (Dlk1-Dio3) is located on
46                                       Type I iodothyronine deiodinase is a approximately 50-kDa, inte
47  thyroid hormone (TH) receptor or a type-III iodothyronine deiodinase transgene in the nervous system
48                                       Type 2 iodothyronine deiodinase, an enzyme involved in the conv
49 s the actin-based endocytosis of the type II iodothyronine deiodinase.
50 or reciprocal regulation of types II and III iodothyronine deiodinases (Dio2 and Dio3, respectively),
51                                              Iodothyronine deiodinases (Dios) are important selenopro
52 hat antithyroid drug treatment and targeting iodothyronine deiodinases (DIOs) to suppress cellular tr
53                                              Iodothyronine deiodinases (IDs) are mammalian selenoenzy
54 ly (GPX1, GPX2, GPX3, and GPX4), one or more iodothyronine deiodinases and two thioredixin reductases
55                                          The iodothyronine deiodinases are a family of oxidoreductase
56                                Types 1 and 3 iodothyronine deiodinases are known to be selenocysteine
57 ins containing redox-active cysteines or the iodothyronine deiodinases containing an active site sele
58                                    Targeting iodothyronine deiodinases locally in the retina is a the
59 d selenoprotein genes encoding type I and II iodothyronine deiodinases, respectively.
60 oral dependency, we investigated the role of iodothyronine deiodinases, which in target tissues conve
61 Cl(-) uptake was inhibited differentially by iodothyronine derivatives.
62 r TH level is mainly regulated by deiodinase iodothyronine (DIO)-2 and -3.
63 and experimental evidence for the use of tri-iodothyronine during cardiac surgery are reviewed.
64 s of thyroid-stimulating hormone or free tri-iodothyronine, free tetra-iodothyronine decreased by 19%
65                       A new study shows that iodothyronines induce metamorphosis in the cephalochorda
66                                              Iodothyronine-induced metamorphosis may be an ancestral
67  with decreased concentrations of plasma tri-iodothyronine, low thyroxine, and normal range or slight
68 lled in a randomized controlled trial of tri-iodothyronine+/-methylprednisolone [MP] therapy) undergo
69  and liothyronine (the synthetic form of tri-iodothyronine) nor the use of desiccated thyroid extract
70 eceptors, rapid (5 s) actions of a series of iodothyronines on muscimol-stimulated uptake of (36)Cl(-
71 at Tyr130 is an important donor of the outer iodothyronine ring.
72                                   The type 3 iodothyronine selenodeiodinase (D3) is an integral membr
73                                 This low tri-iodothyronine state may have significant hemodynamic con
74                              Clinically, tri-iodothyronine supplementation after cardiac surgery impr
75 evidence has accumulated suggesting that tri-iodothyronine supplementation to the ischemically injure
76 tual and motor disability and high serum tri-iodothyronine (T(3)) concentrations (Allan-Herndon-Dudle
77     Thyroid hormone thyroxine (T(4)) and tri-iodothyronine (T(3)) production is regulated by feedback
78 lls treated (24 h) with a combination of tri-iodothyronine (T(3), 10 nM) and dexamethasone (200 nM).
79                   Thyroid hormone 3,5,3'-tri-iodothyronine (T3) binds and activates thyroid hormone r
80 hyperthyroidism, we administered 200 mug tri-iodothyronine (T3) in 7- and 27-mo-old rats for 14 d.
81 accomplished by injecting suspensions of tri-iodothyronine (T3) in coconut oil into the midbrain vent
82 Both glucose-insulin-potassium (GIK) and tri-iodothyronine (T3) may improve cardiovascular performanc
83  deiodinases (DIOs) to suppress cellular tri-iodothyronine (T3) production or increase T3 degradation
84                        Here we show that tri-iodothyronine (T3) treatment in mice acutely and specifi
85 fter stimulation, in vivo, for 24 h with tri-iodothyronine (T3).
86  (subnormal ratio of free thyroxine:free tri-iodothyronine [T3], low concentration of total reverse T
87                         Thyroid hormones are iodothyronines that control growth and development, as w
88 ing the reductive elimination of iodide from iodothyronines through a poorly understood mechanism.
89 f the delta-like homolog 1 (Dlk1)-deiodinase iodothyronine type III (Dio3) locus are up-regulated in
90  insulin, cortisol, parathyroid hormone, tri-iodothyronine uptake (T3 uptake), and free thyroxine ind
91             Molecular modeling of the active iodothyronines using the Gaussian03 series of programs i