ライフサイエンスコーパス: ion conductance

1 nction (altered basolateral --> apical Cl(-) ion conductance).

2 this stabilization is a major determinant of ion conductance.

3 finity for the transmitter and no measurable ion conductance.

4 ion of epithelial calcium-activated chloride ion conductance.

5 p is independent of changes in E(m) or total ion conductance.

6 ly rises up to tenfold and is accompanied by ion conductance.

7 of the cardioprotective significance of this ion conductance.

8 he latter phase concurrent with the start of ion conductance.

9 llular side of transmembrane domain three in ion conductance.

10 but only A(A799I) exhibits an A(A799V)-like ion conductance.

11 l applications requiring chemical control of ion conductance.

12 ila neurons that was not based on changes in ion conductance.

13 romoting vesicle aggregation, and regulating ion conductances, all in a Ca2+-dependent manner.

14 switches between an open state that permits ion conductance and a closed state that prevents permeat

15 o-tip direction, the funnel exhibits a lower ion conductance and a higher electroosmotic flow velocit

16 p-to-base direction, the funnel has a higher ion conductance and a lower electroosmotic flow velocity

17 We combined nanoscale live-cell scanning ion conductance and fluorescence resonance energy transf

18 in folding and design, and the mechanisms of ion conductance and gating, but also in more applicative

19 The temporal correlation between ion conductance and hydration of helices holds for fast

20 Herein, we have examined the barriers to ion conductance and origins of ion selectivity in models

21 We have developed a hybrid scanning ion conductance and scanning near-field optical microsco

22 t lumen width, through calculations of their ion conductance and selectivity based on all-atom molecu

23 00 side chains are major determinants of RyR ion conductance and selectivity.

24 O2, mediate the photocurrents with different ion conductance and selectivity.

25 pens the way to elucidating the mechanism of ion conductance and selectivity.

26 the plasma membrane that counteracts inward ion conductance and therefore limits neuronal excitabili

27 f PKC is required for PDBu activation of VR1 ion conductance, and is independent of the vanilloid sit

28 aracteristics, their expression of intrinsic ion conductances, and their responsiveness to chronic 6-

29 Our simulated ion conductance approaches that obtained experimentally

30 ional model in which detailed morphology and ion conductance are paired with intracellular ATP produc

31 Water efflux and the cessation of the ion conductance are synchronized as well, with a time co

32 c phospholemman, Mat-8 and renal CHIF, large ion conductances are activated when gamma subunits are e

33 urrent at -60 mV suggested that at least two ion conductances are involved in the pacemaking of the c

34 However, it is unclear which ion conductances are responsible for PKA-induced nocicep

35 ese transitions are well-defined in terms of ion conductance, but their structural basis is poorly un

36 ed the ability to bind to PA pores and block ion conductance, but they were unable to translocate acr

37 These structural features explain high ion conductance by RyRs and the long-range allosteric re

38 n permeation free energy profile and maximum ion conductance calculated from the MS-EVB simulation da

39 that both mechanisms may lead to changes in ion conductances, cell excitability and Ca(2+) influx un

40 PPase signature residues located outside the ion conductance channel identified earlier in PPases usi

41 and human AMs were characterized by scanning ion conductance, confocal, and electron microscopy.

42 novel method, we have recently described an ion conductance consistent with mitochondrial permeabili

43 ctive drug dexpramipexole (DEX) inhibited an ion conductance consistent with this c-subunit channel (

44 owing in the rate at which a Mg(2+)-specific ion conductance deactivates following membrane excitatio

45 r buffer with submicrometer resolution using ion conductance distance control to demonstrate the feas

46 and the influence of the modified dipoles on ion conductance estimated.

47 +), explaining the >100 times larger maximal ion conductance for the latter, in qualitative agreement

48 Loss of CFTR-mediated chloride ion conductance from the apical plasma membrane of epith

49 nd assessed the impact of defective chloride ion conductance, genotype, and colonization status on mi

50 with that of genes involved in transmembrane ion conductances (i.e., channels), exocytosis, and rho/r

51 B011 was the most potent blocker of the AQP1 ion conductance (IC50 of 14 muM), with no effect on wate

52 t a method based on superresolution scanning ion conductance imaging of small synapses in culture at

53 suggest that Gly 230 is critical for normal ion conductance in hClC-1 and that this residue resides

54 and are found to irreversibly inhibit sodium ion conductance in recombinantly expressed wild-type sod

55 bic constriction is the major determinant of ion conductance in the GLIC pentameric ion channel.

56 n indole side chains have a direct impact on ion conductance in the gramicidin channel.

57 ny Kv channels undergo a progressive loss of ion conductance in the presence of a prolonged voltage s

58 In order to examine ion conductance in the stem of the channel, we used Venu

59 cyclosporine A (CSA) inhibited increases in ion conductance in whole rat brain-derived mitochondria

60 Specific ion conductances in subcellular compartments must also b

61 ttern results from combinations of intrinsic ion conductances, inhibitory and excitatory synaptic inp

62 The basic idea is that there is a change of ion conductance inside a nanopipet probe when it approac

63 We show that ion conductance is mediated, in part, by hydrogen bondin

64 ce is presented that shows that the membrane ion conductance is not increased during the complete cyc

65 Two-pore domain potassium (K2P) channel ion conductance is regulated by diverse stimuli that dir

66 How ABC proteins regulate ion conductances is unknown, but must generally involve

67 ning ion conductance microscopy (P-SICM) for ion-conductance measurement in polymer membranes and epi

68 f simultaneous quantitative voltammetric and ion conductance measurements and also identify a general

69 High-resolution ion conductance measurements through the Tom40 channel i

70 e substrate is a working electrode, and both ion-conductance measurements between the QRCEs in the tw

71 studies have also allowed us to identify the ion conductance mechanism and its relation to water move

72 Combined scanning electrochemical-scanning ion conductance microcopy (SECM-SICM) has been used to m

73 namic flow through a nanopipet in a scanning ion conductance microscope (SICM) can exert localized fo

74 The scanning ion conductance microscope (SICM) is a powerful tool for

75 The scanning ion conductance microscope (SICM) is an emerging tool fo

76 lize, but recent work has shown the scanning ion conductance microscope (SICM) to be a very promising

77 e was studied with a four-electrode scanning ion conductance microscope (SICM).

78 stems, as demonstrated herein for a scanning ion conductance microscope setup.

79 sible with previous versions of the scanning ion conductance microscope.

80 ingMode atomic force microscope and scanning ion conductance microscope.

81 be the development of a bioinspired scanning ion conductance microscopy (bio-SICM) approach that coup

82 cently, we described potentiometric-scanning ion conductance microscopy (P-SICM) for ion-conductance

83 trumental technique, potentiometric scanning ion conductance microscopy (P-SICM), that utilizes a nan

84 h a technique termed potentiometric scanning ion conductance microscopy (P-SICM).

85 integrating plasmonic imaging with scanning ion conductance microscopy (SICM) and other scanning pro

86 nanopipet that enables simultaneous scanning ion conductance microscopy (SICM) and scanning electroch

87 tein nanopores with high-resolution scanning ion conductance microscopy (SICM) extends the utility of

88 al imaging is demonstrated, using a scanning ion conductance microscopy (SICM) format.

89 Scanning ion conductance microscopy (SICM) has developed into a p

90 Scanning ion conductance microscopy (SICM) is a nanopipette-based

91 Scanning ion conductance microscopy (SICM) is a powerful techniqu

92 Scanning ion conductance microscopy (SICM) is a scanned probe mic

93 Scanning ion conductance microscopy (SICM) is a scanning probe te

94 Scanning ion conductance microscopy (SICM) is a super-resolution

95 Scanning ion conductance microscopy (SICM) is demonstrated to be

96 ll surfaces that allows noninvasive scanning ion conductance microscopy (SICM) of cells and which mus

97 Scanning ion conductance microscopy (SICM) offers the ability to

98 Scanning ion conductance microscopy (SICM) offers the ability to

99 d use of nanoscale dual function pH-scanning ion conductance microscopy (SICM) probes is reported.

100 We report a novel scanning ion conductance microscopy (SICM) technique for assessin

101 oscience, particularly when used in scanning ion conductance microscopy (SICM) to determine, in a non

102 Scanning ion conductance microscopy (SICM) was used to interrogat

103 With scanning ion conductance microscopy (SICM), a noncontact scanning

104 clamping, confocal microscopy, and scanning ion conductance microscopy (SICM).

105 We used scanning ion conductance microscopy and conventional cell-attache

106 We conclude that scanning ion conductance microscopy can be used to follow the tim

107 Scanning ion conductance microscopy imaging of battery electrodes

108 ied by intact axons identified with scanning ion conductance microscopy in primary hippocampal cultur

109 We describe hopping mode scanning ion conductance microscopy that allows noncontact imagin

110 in-coated pit dynamics in living cells using ion conductance microscopy to directly image the changes

111 We used scanning ion conductance microscopy to image changes in the surfa

112 rements were performed by utilizing scanning ion conductance microscopy to measure the change in resi

113 a novel recording approach based on scanning ion conductance microscopy to resolve tight junction per

114 ing a combination of macropatch and scanning ion conductance microscopy we show that loss of Scn1b in

115 ing a combination of macropatch and scanning ion conductance microscopy we show that loss of Scn1b in

116 signals, using a combined nanoscale scanning ion conductance microscopy-Forster resonance energy tran

117 ording, we identified a novel determinant of ion conductance near the point of entry of permeant ions

118 on-selective, and calcium-activated vacuolar ion conductance of 320 pS (yeast vacuolar conductance, Y

119 lization with individual oligomers producing ion conductances of <10 pS/pore.

120 that conclusively explain ChR activation and ion conductance on the basis of chromophore isomerizatio

121 processes and despite a strong dependence of ion conductances on temperature.

122 glial stimulation did not affect transmural ion conductance or cell-impermeant dye flux but the base

123 es oriented toward the bilayer center on the ion conductance pathway for the Streptomyces K(+) channe

124 t be close to the extracellular mouth of the ion conductance pathway.

125 eir ability to interact with lipids, opening ion conductance pathways in artificial membranes, and in

126 es into artificial lipid bilayer openings of ion conductance pathways.

127 We propose that these major ion conductances play an essential role in membrane volt

128 olecular determinants that define the unique ion conductance properties of this protein are not well

129 ransporters mediate multidrug resistance and ion conductance regulation.

130 RCEs in the electrolyte channels provides an ion conductance signal that is used to control and posit

131 of these residues was observed to affect the ion conductance, suggesting the seven His-144 to compris

132 Cross-correlation analysis revealed that ion conductance tallies with peptide backbone amide I vi

133 The ion selectivity of a membrane ion conductance that is inactivated by extracellular cal

134 cking, but several studies have described an ion conductance that results from PLM expression in oocy

135 vious studies suggest that the unique set of ion conductances that drive spontaneous, rhythmic firing

136 Measurements of ion conductance through alpha-hemolysin pore in a bilaye

137 s reminiscent of earlier reports of possible ion conductance through PLN pentamers.

138 by a measurable change in the single channel ion conductance through pores of the ion channel-forming

139 diseases in which alterations in control of ion conductance through the central pore of ion channels

140 ulations, we investigated the feasibility of ion conductance through the pore of the bellflower model

141 or cell-impermeant dye flux but the baseline ion conductance was more variable in Sox10::CreER(T2+/-)

142 elucidate the cation permeability pathway of ion conductance, we performed cysteine scanning mutagene

143 changes in transmembrane potential (E(m)) or ion conductance, we studied electrical currents and drug

144 their permeability to dyes and small atomic ions (conductance) were not proportional.

145 Among them, Gln-56 is important for ion conductance, whereas Ser-63, Thr-250, and Asn-258 ar

146 ion-controlled to water-splitting controlled ion conductance, with a large ion current signature that

147 mutants (D4938N, D4945N) showed a reduced K+ ion conductance, with D4938N also exhibiting a reduced s