ライフサイエンスコーパス: ion pump

1 smitter delivery from the organic electronic ion pump.

2 as well as ion channels and the Na/K-ATPase ion pump.

3 rotein interactions, in addition to being an ion pump.

4 high-resolution structure of this ATP-driven ion pump.

5 a threonine, that protein became a chloride ion pump.

6 e channel-forming small molecule and protein ion pumps.

7 perometric biosensors and organic electronic ion pumps.

8 opulations that had already evolved distinct ion pumps.

9 while eukaryotic V-type ATPases function as ion pumps.

10 tivation of vision pigments and light-driven ion pumps.

11 realized previously using organic electronic ion pumps.

12 branch of P-type ATPases, a large family of ion pumps.

13 action cycle of this family of ATP-dependent ion pumps.

14 and a member of the P-type ATPase family of ion pumps.

15 anism may be a progenitor of photobiological ion pumps.

16 is performing cellular functions other than ion pumping.

17 all design principles that are necessary for ion pumping.

18 The ion pumps (active in the membrane at numbers exceeding 2

19 sequence primarily of the ability to depress ion pumping activities of cells, macromolecular synthesi

20 ring from the vacuolar-type (V-type) sodium ion-pumping adenosine triphosphatase (Na+-ATPase) from E

21 By assessing the energy used on postsynaptic ion pumping and action potentials, we show that, instead

22 fferences between the two domains, including ion pumping and DNA replication.

23 Primary ion pumps and antiporters exist as multigene families in

24 ) in M6, also play critical roles in related ion pumps and are therefore likely to be common architec

25 ing extensively studied, the central role of ion pumps and carriers is largely ignored in current neu

26 ns is based on the operation of plasmalemmal ion pumps and carriers that establish transmembrane ion

27 s directly regulate the genes of a number of ion pumps and channels, these results suggest that Na(+)

28 f the protein may be the shared mechanism of ion pumps and G-protein related receptors.

29 ers such as inositol trisphosphate, cellular ion pumps and membrane channels has become more clearly

30 dings affirm the alternating-access model of ion pumps and offer the possibility of examining ion occ

31 hy membrane bioenergetics are universal, yet ion pumps and phospholipid membranes arose later and ind

32 ents have not been observed in retinal-based ion pumps and photoreceptors.

33 This may open new avenues for the study of ion pumps and similar electrogenic targets.

34 in this enzyme, a cytochrome c oxidase-type ion-pump and a Q-cycle mechanism, on the basis of the th

35 ermeation, mechanosensitive channels, active ion pumps, and active stresses in the cortex.

36 Ion pumps are integral membrane proteins responsible for

37 biological entities such as ion channels and ion pumps as a function of ion type and concentration.

38 Th?e atomic structure of the light-driven ion pump bacteriorhodopsin and the surrounding lipid mat

39 umping Ca(2+) (which uses 1 ATP per 2 Ca(2+) ions pumped), but by the 10th and subsequent twitches th

40 s to the previously unknown structure of the ion-pumping channel in the C-type Coxs and provides insi

41 ons contain open reading frames for a P-type ion pump (CopA) with homology to Cd2+ and Cu2+ ATPases a

42 ly are believed to be bacterial redox-driven ion pumps, coupling an oxidoreduction process to the tra

43 es E1/E2 conformational transition during an ion pumping cycle.

44 Like many voltage-sensitive ion pumps, cytochrome c oxidase is inhibited by zinc.

45 diverse protein families, including V-ATPase ion pumps, DNA-binding transcription regulators, and ser

46 oth an energy reserve, capable of sustaining ion pumping during periods of transient stress, as well

47 Steady-state measurements indicate an ion pumping efficiency of approximately 30%.

48 ells that harbor phosphorylases and kinases, ion pumps exhibiting substantial ATPase activity, and my

49 mbrane Ca(2+) ATPase 2 (PMCA2), an essential ion pump expressed exclusively in grey matter and involv

50 of these structural changes reveals how this ion pump first facilitates ion uptake deep within the ce

51 rotein promise a better understanding of how ion pumps function.

52 , suggesting that the signal-transducing and ion-pumping functions of Na(+)/K(+)-ATPase cooperate in

53 says confirmed the alkaline induction of two ion pump genes (ENA1 and VMA4), several ion limitation g

54 Because Rim101p activates ion pump genes, we tested the role of RIM101 in ion home

55 One example compares the inward ion pump halorhodopsin (HR) and the outward proton pump

56 Na(+)/K(+)-ATPase as an energy transducing ion pump has been studied extensively since its discover

57 ynaptic strengths or ionic conductances, and ion pumps have only rarely been demonstrated to play a d

58 of ion homeostasis that can be recovered by ion pumps if the energy supply is adequate.

59 to isolate the energetics of an electrogenic ion pump in an engineered in vitro environment to power

60 es hydrolyze ATP in the V1 domain coupled to ion pumping in VO.

61 up of P-type ATPases, an essential family of ion pumps in all kingdoms of life.

62 ach, using the fast generation of functional ion pumps incorporated into nanodiscs and their subseque

63 ating that the Drosophila Na,K-ATPase has an ion-pump-independent role in junction formation and trac

64 lthough halorhodopsin is normally a chloride ion pump, it evidently contains all structural requireme

65 more likely than a cytochrome c oxidase-type ion-pump mechanism.

66 Rhodopsins are light-driven ion-pumping membrane proteins found in many organisms an

67 A microfluidic ion pump (microFIP), capable of delivering a drug withou

68 In the related ion pumps Na(+),K(+)-ATPase and Ca(2+)-ATPase, M4 moves

69 sons: glycolytic enzymes are associated with ion pumps; neurons may increase their energy supply by a

70 The organic electronic ion pump (OEIP) provides flow-free and accurate delivery

71 r promote active or passive ion transport as ion pumps or directly light-activated channels.

72 l rhodopsins, which function as light-driven ion pumps or photosensors, have been reported.

73 x proteins that function as light-responsive ion pumps or sensory receptors.

74 tion that occlusion/deocclusion reactions of ion pumps perturb the membrane surrounding the protein,

75 stidine-tagged yeast secretory pathway/Golgi ion pump Pmr1 to near homogeneity in one step, using nic

76 nerated in the yeast secretory pathway/Golgi ion pump, Pmr1, targeting oxygen-containing side chains

77 e insight on the structural mechanism of the ion pumping process.

78 -dependent activation of an energy-consuming ion pumping process.

79 We reconstituted a model vectorial ion pump, proteorhodopsin, in liposomes of opposite char

80 d seem to be simply to optimize the enzyme's ion pumping rate under its normal physiological conditio

81 pairs may be a general feature of P2-ATPase ion pumps, reflecting a flexibility of this region that

82 ndicate that PMR1 and PMR2A, encoding P-type ion pumps required for Mn2+ and Na+ tolerance, may also

83 -ATPase are electrogenic and nonelectrogenic ion pumps, respectively.

84 Inactivation of Na+,K+ -ATPases, the ion pumps responsible for maintaining a pH above 6 withi

85 RNA interference of the H(+),K(+)-ATPase ion pump results in membrane hyperpolarization, which ha

86 which is lower than that of other microbial ion pumping rhodopsins.

87 However, organic electronic ion pumps show high operating voltages and limited trans

88 nt, suggesting activation of an electrogenic ion pump such as the H+ pump.

89 a single ion channel and the activity of an ion pump suffice to dramatically increase the propensity

90 Members of the P-type ATPase ion pump superfamily are found in all three branches of

91 recording electrodes via organic electronic ion pump technology.

92 emical model for the functioning of the V(o) ion pump that is consistent with the known structural fe

93 Na(+)/K(+)-ATPases are transmembrane ion pumps that maintain ion gradients across the basolat

94 e conductors in the form of ion channels and ion pumps that work together to form ion concentration g

95 uces ATP and the cellular processes, such as ion pumping, that consume ATP.

96 collaborating with the corresponding protein ion pumps to restore physiology.

97 lectrochemical gradients provided by primary ion pumps to translocate metabolites or drugs "uphill" a

98 g proteins, and downstream executors such as ion pumps, transporters, and plasma membrane channels th

99 -ATPase beta-subunit (betaHK) into an active ion pump upon coexpression in Xenopus oocytes.

100 , changes in the expression of several other ion pumps, vesicular proteins, mitochondrial enzymes and

101 or the rational design of novel light-driven ion pumps with optogenetic applications.